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Liabilities Related to Sales of Future Royalties - Estimates of Annual Interest Rate (Details) | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2021 | Sep. 30, 2020 | Sep. 30, 2021 | Sep. 30, 2020
2012 Purchase and Sale Agreement |  |  |  |
Liability Related to Sale of Future Royalties [Line Items] |  |  |  |
Implicit interest rate over the life of the agreement | 20.20% | 20.20% | 20.20% | 20.20%
Prospective effective interest rate | 48.00% | 48.00% | 48.00% | 48.00%
2020 Purchase and Sale Agreement |  |  |  |
Liability Related to Sale of Future Royalties [Line Items] |  |  |  |
Implicit interest rate over the life of the agreement | 16.00% |  | 16.00% |
Prospective effective interest rate | 16.00% |  | 16.00% |

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- Definition Estimated annual interest rate over life of royalty liability. + References No definition available. + Details
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- Definition Liability related to sale of future royalties. + References No definition available. + Details
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- Definition Prospective interest rate percentage. + References No definition available. + Details
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- Details
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- Details
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