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Fair Value Measurement (Details) - USD ($) $ in Thousands	Sep. 30, 2021	Dec. 31, 2020
Level 2
Assets:
Available-for-sale investments	$ 891,145	$ 1,003,348
Recurring
Assets:
Total assets	939,481	1,182,650
Liabilities:
Development derivative liability	21,387	0
Recurring | Corporate notes and bonds
Assets:
Available-for-sale investments	329,339	687,469
Recurring | Corporate commercial paper
Assets:
Available-for-sale investments	555,924	313,497
Recurring | Obligations of U.S. government agencies
Assets:
Available-for-sale investments	5,882	2,382
Recurring | Money market funds
Assets:
Money market funds	48,336	179,302
Recurring | Level 1
Assets:
Total assets	48,336	179,302
Liabilities:
Development derivative liability	0	0
Recurring | Level 1 | Corporate notes and bonds
Assets:
Available-for-sale investments	0	0
Recurring | Level 1 | Corporate commercial paper
Assets:
Available-for-sale investments	0	0
Recurring | Level 1 | Obligations of U.S. government agencies
Assets:
Available-for-sale investments	0	0
Recurring | Level 1 | Money market funds
Assets:
Money market funds	48,336	179,302
Recurring | Level 2
Assets:
Total assets	891,145	1,003,348
Liabilities:
Development derivative liability	0	0
Recurring | Level 2 | Corporate notes and bonds
Assets:
Available-for-sale investments	329,339	687,469
Recurring | Level 2 | Corporate commercial paper
Assets:
Available-for-sale investments	555,924	313,497
Recurring | Level 2 | Obligations of U.S. government agencies
Assets:
Available-for-sale investments	5,882	2,382
Recurring | Level 2 | Money market funds
Assets:
Money market funds	0	0
Recurring | Level 3
Assets:
Total assets	0	0
Liabilities:
Development derivative liability	21,387	0
Recurring | Level 3 | Corporate notes and bonds
Assets:
Available-for-sale investments	0	0
Recurring | Level 3 | Corporate commercial paper
Assets:
Available-for-sale investments	0	0
Recurring | Level 3 | Obligations of U.S. government agencies
Assets:
Available-for-sale investments	0	0
Recurring | Level 3 | Money market funds
Assets:
Money market funds	$ 0	$ 0

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