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License and Collaboration Agreements - License, Collaboration and Other Revenue (Detail) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
License And Collaboration Agreements [Line Items]        
Total license, collaboration and other revenue $ 314 $ 1,631 $ 396 $ 55,421
Bristol-Myers Squibb Company | Bempegaldesleukin        
License And Collaboration Agreements [Line Items]        
Total license, collaboration and other revenue 0 0 0 50,000
Eli Lilly and Company | NKTR-358        
License And Collaboration Agreements [Line Items]        
Total license, collaboration and other revenue 0 0 0 1,259
Other        
License And Collaboration Agreements [Line Items]        
Total license, collaboration and other revenue $ 314 $ 1,631 $ 396 $ 4,162