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Commitments and Contingencies (Details) | 12 Months Ended |  |
--- | --- | --- | ---
Dec. 31, 2021 USD ($) action | Dec. 31, 2020 USD ($) | Dec. 31, 2019 USD ($)
Loss Contingencies [Line Items] |  |  |
Purchase commitments related to contract manufacturing, clinical development and certain other items | $ 8,200,000 |  |
Mulquin Action And Damiba Action |  |  |
Loss Contingencies [Line Items] |  |  |
Previous claims | action | 2 |  |
Derivative Action |  |  |
Loss Contingencies [Line Items] |  |  |
New claims | action | 3 |  |
Legal Matters |  |  |
Loss Contingencies [Line Items] |  |  |
Litigation matters, liabilities | $ 0 |  | $ 0
Indemnification Obligation |  |  |
Loss Contingencies [Line Items] |  |  |
Litigation matters, liabilities | 0 | $ 0 |
Merger and Acquisition Related Claims | Maximum |  |  |
Loss Contingencies [Line Items] |  |  |
Obligations under Director and Officer Indemnifications per incident | 10,000,000 |  |
Securities Related Claims |  |  |
Loss Contingencies [Line Items] |  |  |
Obligations under Director and Officer Indemnifications per incident | 10,000,000 |  |
Non-Securities Related Claims |  |  |
Loss Contingencies [Line Items] |  |  |
Obligations under Director and Officer Indemnifications per incident | $ 10,000,000 |  |

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