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License and Collaboration Agreements - Additional Information (Details) - USD ($) |  |  | 1 Months Ended | 3 Months Ended | 12 Months Ended |
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Feb. 13, 2018 | Aug. 23, 2017 | Apr. 30, 2018 | Sep. 30, 2017 | Aug. 31, 2017 | Mar. 31, 2016 | Oct. 31, 2010 | Dec. 31, 2021 | Sep. 30, 2021 | Jun. 30, 2021 | Mar. 31, 2021 | Dec. 31, 2020 | Sep. 30, 2020 | Jun. 30, 2020 | Mar. 31, 2020 | Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018 | Jan. 09, 2020
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Potential future additional payments for development milestones |  |  |  |  |  |  |  | $ 1,700,000,000 |  |  |  |  |  |  |  | $ 1,700,000,000 |  |  |  |
Accounts receivable |  |  |  |  |  |  |  | 22,492,000 |  |  |  | $ 38,889,000 |  |  |  | 22,492,000 | $ 38,889,000 |  |  |
Revenue recognized from contracts with customers |  |  |  |  |  |  |  | 25,009,000 | $ 24,921,000 | $ 28,330,000 | $ 23,647,000 | 23,462,000 | $ 30,033,000 | $ 48,847,000 | $ 50,573,000 | 101,907,000 | 152,915,000 | $ 114,617,000 |  |
Bristol Myers Squibb Collaboration Agreement | Nektar 214 | Nektar's |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Global commercialization profits and losses sharing percentage | 65.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of sharing production costs | 65.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront and milestone payments received from license agreements |  |  | $ 1,000,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Maximum total additional cash payments receivable upon achievement of certain development and regulatory milestones |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 1,400,000,000 |  |  |  |
Bristol Myers Squibb Collaboration Agreement | Nektar 214 | Maximum | Nektar's |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eligible additional cash payments receivable upon achievement of certain sales milestones |  |  | $ 350,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Bristol Myers Squibb Collaboration Agreement | Nektar 214 | Opdivo | Nektar's |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of sharing development costs | 32.50% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Nektar-358 | Nektar's |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Received upfront and milestone payment |  |  |  | $ 150,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of sharing in Phase 2 development costs |  | 25.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
NKTR-358 | Nektar's |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred revenue |  |  |  |  |  |  |  | 0 |  |  |  |  |  |  |  | 0 |  |  |  |
Nektar |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of upfront payment, market access milestones, royalties and sales milestones |  |  |  |  |  | 40.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |
Bristol-Myers Squibb | Purchase Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued (in shares) |  |  | 8,284,600 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Sale of stock consideration received |  |  | $ 850,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Bristol-Myers Squibb | Nektar 214 | Research and Development |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Reimbursement of expenses |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 101,500,000 | 128,200,000 |  | $ 105,400,000 |
Bristol-Myers Squibb | BMS Collaboration Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Accounts receivable |  |  |  |  |  |  |  | 21,400,000 |  |  |  | $ 38,700,000 |  |  |  | 21,400,000 | 38,700,000 |  |  |
Company share of development costs, annual cap |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 125,000,000 | 4,000,000 |  |  |
Bristol-Myers Squibb | Bristol Myers Squibb Collaboration Agreement | Purchase Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Total consideration received under agreements |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 1,850,000,000 |
Estimated fair value of shares |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 790,200,000 |
Remaining amount allocated to transaction price |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 50,000,000 |  | $ 1,059,800,000 |
Potential future development, regulatory and sales milestones |  |  |  |  |  |  |  | $ 1,800,000,000 |  |  |  |  |  |  |  | $ 1,800,000,000 |  |  |  |
Bristol-Myers Squibb | Bristol Myers Squibb Collaboration Agreement | Nektar 214 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Global commercialization profits and losses sharing percentage | 35.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of sharing production costs | 35.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Bristol-Myers Squibb | Bristol Myers Squibb Collaboration Agreement | Nektar 214 | Opdivo |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of sharing development costs | 67.50% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eli Lilly and Company | Nektar-358 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Amount of transaction price allocated to performance obligation |  |  |  | 125,900,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue recognized from contracts with customers |  |  |  |  | $ 125,900,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eli Lilly and Company | Nektar-358 | Nektar's |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of regulatory milestones payments will be reduced under certain conditions |  | 50.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of regulatory milestones payments will be reduced if conditions occur |  | 75.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eli Lilly and Company | Nektar-358 | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Potential future additional development and regulatory milestones |  | $ 250,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eli Lilly and Company | Nektar-358 | Maximum | Nektar's |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of funding phase 3 development costs on an indication by indication basis borne |  | 25.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eli Lilly and Company | Nektar-358 | Minimum | Nektar's |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of funding phase 3 development costs on an indication by indication basis borne |  | 0.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eli Lilly and Company | Phase 1 Clinical Development | Nektar-358 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Amount of transaction price allocated to performance obligation |  |  |  | 17,600,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eli Lilly and Company | Drug Product Development | Nektar-358 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Amount of transaction price allocated to performance obligation |  |  |  | $ 6,500,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eli Lilly | Nektar-358 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of sharing in Phase 2 development costs |  | 75.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Amgen, Inc. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Received upfront and milestone payment |  |  |  |  |  |  | $ 50,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |
Amgen, Inc. | Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2022-01-01 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue period of recognition |  |  |  |  |  |  |  | 10 years |  |  |  |  |  |  |  | 10 years |  |  |  |
Other |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Potential future additional payments for development milestones |  |  |  |  |  |  |  | $ 40,000,000 |  |  |  |  |  |  |  | $ 40,000,000 |  |  |  |
Terminated Partnership |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred revenue |  |  |  |  |  |  |  | $ 2,000,000 |  |  |  |  |  |  |  | $ 2,000,000 |  |  |  |
Milestone One | Bristol Myers Squibb Collaboration Agreement | Nektar 214 | Nektar's |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Potential future additional payments for development milestones |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 25,000,000

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