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Liabilities Related to the Sales of Future Royalties - Schedule of Liability Related to Potential Future Royalties (Detail) - USD ($) $ in Thousands | 12 Months Ended | 118 Months Ended
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Dec. 31, 2021 | Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2021
Liability Related To Sale Of Future Royalties [Roll Forward] |  |  |  |  |
Liabilities related to the sales of future royalties—beginning balance | $ 205,255 |  |  |  | $ 0
Royalty monetization proceeds | 0 |  |  |  | 274,000
Non-cash royalty revenue | (77,746) |  | $ (48,563) | $ (36,303) | (333,451)
Non-cash interest expense | 47,313 |  | 30,267 | $ 25,044 | 244,273
Payments to RPI | 0 |  |  |  | (10,000)
Loss on revaluation of liability related to the sale of future royalties | (23,522) |  |  |  | (23,522)
Liabilities related to the sales of future royalties – ending balance | 198,344 | $ 198,344 | 205,255 |  | 198,344
Less: unamortized transaction costs | (2,917) | (2,917) |  |  | (2,917)
Liabilities related to the sales of future royalties, net | 195,427 | 195,427 | 200,340 |  | 195,427
2012 Purchase and Sale Agreement |  |  |  |  |
Liability Related To Sale Of Future Royalties [Roll Forward] |  |  |  |  |
Liabilities related to the sales of future royalties—beginning balance | 65,880 |  |  |  | 0
Royalty monetization proceeds | 0 |  |  |  | 124,000
Non-cash royalty revenue | (37,578) |  |  |  | (282,658)
Non-cash interest expense | 26,458 |  |  |  | 223,418
Payments to RPI | 0 |  |  |  | (10,000)
Loss on revaluation of liability related to the sale of future royalties | (23,522) |  |  |  | (23,522)
Liabilities related to the sales of future royalties – ending balance | 78,282 | 78,282 | 65,880 |  | 78,282
Less: unamortized transaction costs | 0 | 0 |  |  | 0
Liabilities related to the sales of future royalties, net | 78,282 | 78,282 |  |  | 78,282
2020 Purchase and Sale Agreement |  |  |  |  |
Liability Related To Sale Of Future Royalties [Roll Forward] |  |  |  |  |
Liabilities related to the sales of future royalties—beginning balance | 139,375 | 0 |  |  |
Royalty monetization proceeds | 0 | 150,000 |  |  |
Non-cash royalty revenue | (40,168) | (50,793) |  |  |
Non-cash interest expense | 20,855 | 20,855 |  |  |
Payments to RPI | 0 | 0 |  |  |
Loss on revaluation of liability related to the sale of future royalties |  | 0 |  |  |
Liabilities related to the sales of future royalties – ending balance | 120,062 | 120,062 | $ 139,375 |  | 120,062
Less: unamortized transaction costs | (2,917) | (2,917) |  |  | (2,917)
Liabilities related to the sales of future royalties, net | $ 117,145 | $ 117,145 |  |  | $ 117,145

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- Definition Gain (Loss) ON Revaluation Of Liabilities Related To The Sale Of Future Royalties, Gross + References No definition available. + Details
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- Definition Liabilities on sale of future royalties, unamortized transaction costs. + References No definition available. + Details
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- Definition Liability Related To Sale Of Future Royalties + References No definition available. + Details
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- Definition Liability related to sale of potential future royalties noncurrent. + References No definition available. + Details
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- Definition Liability related to sale of potential future royalties non current net of issuance costs. + References No definition available. + Details
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- Details
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