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License and Collaboration Agreements - Additional Information (Details) - USD ($) |  |  | 1 Months Ended | 3 Months Ended |  |
--- | --- | --- | --- | --- | --- | ---
Feb. 13, 2018 | Aug. 23, 2017 | Apr. 30, 2018 | Sep. 30, 2017 | Mar. 31, 2022 | Mar. 31, 2021 | Dec. 31, 2021 | Dec. 31, 2020
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Accounts receivable |  |  |  |  | $ 30,220,000 |  | $ 22,492,000 |
Bristol Myers Squibb Collaboration Agreement |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Accounts receivable |  |  |  |  | 26,900,000 |  | $ 21,400,000 |
Bristol Myers Squibb Company | Purchase Agreement |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Shares issued (in shares) |  |  | 8,284,600 |  |  |  |  |
Sale of stock consideration received |  |  | $ 850,000,000 |  |  |  |  |
Other Partner |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Potential future additional payments for development milestones (up to) |  |  |  |  | 40,000,000 |  |  |
Nektar-358 | Nektar's |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Received upfront and milestone payment |  |  |  | $ 150,000,000 |  |  |  |
Percentage of sharing in Phase 2 development costs |  | 25.00% |  |  |  |  |  |
Nektar-358 | Eli Lilly And Company | Maximum |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Potential future additional development and regulatory milestones (up to) |  | $ 250,000,000 |  |  |  |  |  |
Nektar-358 | Eli Lilly And Company | Nektar's |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Percentage of regulatory milestones payments will be reduced under certain conditions |  | 50.00% |  |  |  |  |  |
Percentage of regulatory milestones payments will be reduced if conditions occur |  | 75.00% |  |  |  |  |  |
Nektar-358 | Eli Lilly And Company | Nektar's | Maximum |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Percentage of funding phase 3 development costs on an indication by indication basis borne |  | 25.00% |  |  |  |  |  |
Nektar-358 | Eli Lilly |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Percentage of sharing in Phase 2 development costs |  | 75.00% |  |  |  |  |  |
Nektar 214 | Bristol Myers Squibb Company | Research and Development Expense |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Reimbursement of expenses |  |  |  |  | $ 24,900,000 | $ 26,700,000 |  |
Nektar 214 | Bristol Myers Squibb Collaboration Agreement | Nektar's |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Percentage of sharing production costs | 65.00% |  |  |  |  |  |  |
Upfront and milestone payments received from license agreements |  |  | $ 1,000,000,000 |  |  |  |  |
Nektar 214 | Bristol Myers Squibb Collaboration Agreement | Nektar's | Milestone One |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Potential future additional payments for development milestones (up to) |  |  |  |  |  |  |  | $ 50,000,000
Nektar 214 | Bristol Myers Squibb Collaboration Agreement | Bristol Myers Squibb Company |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Percentage of sharing production costs | 35.00% |  |  |  |  |  |  |
Nektar 214 | Opdivo | Bristol Myers Squibb Collaboration Agreement | Nektar's |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Percentage of sharing development costs | 32.50% |  |  |  |  |  |  |
Nektar 214 | Opdivo | Bristol Myers Squibb Collaboration Agreement | Bristol Myers Squibb Company |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Percentage of sharing development costs | 67.50% |  |  |  |  |  |  |

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