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Stock-Based Compensation (Tables) | 9 Months Ended
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Sep. 30, 2022
Share-Based Payment Arrangement [Abstract] |
Schedule of Stock-Based Compensation Expense | We recognized total stock-based compensation expense in our Condensed Consolidated Statements of Operations as follows (in thousands):
| Three Months Ended September 30, |  | Nine Months Ended September 30,
| 2022 |  | 2021 |  | 2022 |  | 2021
Cost of goods sold | $ | 720 |  |  | $ | 688 |  |  | $ | 2,037 |  |  | $ | 2,131 |
Research and development | 5,422 |  |  | 14,138 |  |  | 22,215 |  |  | 41,779 |
General and administrative | 5,369 |  |  | 9,831 |  |  | 18,401 |  |  | 28,359 |
Restructuring, impairment and other costs of terminated program | 1,007 |  |  | — |  |  | 1,929 |  |  | — |
Total stock-based compensation | $ | 12,518 |  |  | $ | 24,657 |  |  | $ | 44,582 |  |  | $ | 72,269 |
Schedule of Share-based Compensation, Activity | We issued stock-based awards of our common stock as follows (shares in thousands):
| Three Months Ended September 30, |  | Nine Months Ended September 30,
| 2022 |  | 2021 |  | 2022 |  | 2021
Options granted | 5,890 |  |  | 397 |  |  | 6,019 |  |  | 674 |
Weighted-average grant-date fair value of options granted | $ | 3.23 |  |  | $ | 9.36 |  |  | $ | 3.24 |  |  | $ | 9.72 |
RSUs granted | 3,896 |  |  | 727 |  |  | 4,905 |  |  | 1,614 |
Weighted-average grant-date fair value of RSUs granted | $ | 4.73 |  |  | $ | 16.48 |  |  | $ | 4.98 |  |  | $ | 17.98 |

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