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Property, Plant and Equipment (Tables) | 12 Months Ended
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Dec. 31, 2022
Property, Plant and Equipment [Abstract] |
Schedule of Property, Plant and Equipment | Property, plant and equipment consists of the following (in thousands):
| December 31,
| 2022 |  | 2021
Building and leasehold improvements | $ | 74,889 |  |  | $ | 97,385 |
Laboratory equipment | 24,243 |  |  | 42,704 |
Computer equipment and software | 26,205 |  |  | 28,829 |
Manufacturing equipment | 25,052 |  |  | 22,374 |
Furniture, fixtures, and other | 4,263 |  |  | 10,094 |
Depreciable property, plant and equipment at cost | 154,652 |  |  | 201,386 |
Less: accumulated depreciation | (124,731) |  |  | (148,039) |
Depreciable property, plant and equipment, net | 29,921 |  |  | 53,347 |
Construction-in-progress | 2,530 |  |  | 7,163 |
Property, plant and equipment, net | $ | 32,451 |  |  | $ | 60,510 |
We recorded the gains and losses as follows (in thousands):
| Year Ended December 31, 2022
Proceeds from sales |  | $ | 13,196 |
Net book value of assets |  | 9,870 |
Total (gain) loss on sale or disposal of property, plan and equipment, net |  | (3,326) |

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- Definition Tabular disclosure of physical assets used in the normal conduct of business and not intended for resale. Includes, but is not limited to, balances by class of assets, depreciation and depletion expense and method used, including composite depreciation, and accumulated deprecation. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 1 -URI https://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229 + Details
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