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Restructuring, Impairment and Other Costs of Terminated Program - Narrative (Details) $ in Thousands |  |  | 1 Months Ended | 3 Months Ended | 7 Months Ended | 9 Months Ended | 12 Months Ended |
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Dec. 31, 2022 | May 31, 2022 | Apr. 30, 2022 | Dec. 31, 2022 USD ($) | Dec. 31, 2022 USD ($) | Dec. 31, 2022 USD ($) | Dec. 31, 2022 USD ($) | Dec. 31, 2021 USD ($) | Dec. 31, 2020 USD ($) | Jun. 30, 2022
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |
Impairment of right-of-use assets and property, plant and equipment |  |  |  |  |  |  | $ 65,761 | $ 0 | $ 0 |
Book value in excess of fair value |  |  |  |  | $ 67,875 |  |  |  |  |
Third St. Facility |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |
Book value in excess of fair value |  |  |  | $ 12,000 |  |  |  |  |  |
Measurement Input, Market Participant Subtenant Borrowing Rate |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |
Operating lease, measurement input | 7.90% | 6.40% |  |  |  |  |  |  |  |
Nektar 214 | Bristol-Myers Squibb |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |
Reimbursement of expenses |  |  |  |  |  | $ 20,800 |  |  |  |
Employee Severance |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |
Percent of positions eliminated |  |  | 70.00% |  |  |  |  |  |  |
Entity number of employees |  |  | 225 |  |  |  |  |  |  | 735

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