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Restructuring, Impairment and Costs of Terminated Program, and Impairment of Goodwill - Narrative (Details) - USD ($) $ in Thousands | 1 Months Ended | 3 Months Ended | 9 Months Ended | 12 Months Ended | 21 Months Ended
--- | --- | --- | --- | --- | ---
Jun. 30, 2023 | Jan. 31, 2023 | Apr. 30, 2022 | Sep. 30, 2023 | Jun. 30, 2023 | Mar. 31, 2023 | Dec. 31, 2022 | Sep. 30, 2022 | Jun. 30, 2022 | Mar. 31, 2022 | Sep. 30, 2023 | Sep. 30, 2022 | Dec. 31, 2022 | Sep. 30, 2023
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-cash impairment charges |  |  |  | $ (10,567) |  |  |  |  |  |  | $ (35,329) | $ (53,401) |  |
Impairment of other property, plant and equipment |  |  |  |  |  | $ 1,700 |  |  |  |  | 1,299 | 5,120 |  |
Gain on net impairment |  |  |  |  |  |  |  |  |  |  | 1,300 |  |  |
Impairment of goodwill |  |  |  | 0 |  | 76,500 |  | $ 0 |  |  | 76,501 | 0 |  |
Nektar 214 | Research and Development Expense | Bristol Myers Squibb Company |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Reimbursement of expenses |  |  |  |  |  |  |  | 8,300 |  | $ 24,900 |  | 16,700 |  |
2022 Restructuring Plan |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-cash impairment charges |  |  |  | (1,467) | $ (13,255) | 0 | $ (12,361) | (1,200) | $ (52,200) |  |  | (80,483) |  |
Contract termination and other restructuring costs |  |  |  | 0 |  |  |  | 5,023 |  |  | 878 | $ 7,064 |  | $ 11,800
2023 Restructuring Plan |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-cash impairment charges |  |  |  | 10,200 |  | 11,500 |  |  |  |  | 36,600 |  |  |
Contract termination and other restructuring costs |  |  |  | 0 |  |  |  |  |  |  | 34 |  |  |
2023 Restructuring Plan | Third St. Facility |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-cash impairment charges |  |  |  |  | 6,200 |  |  |  |  |  |  |  |  |
2023 Restructuring Plan | Mission Bay Facility |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-cash impairment charges |  |  |  | 10,600 | $ 7,100 |  |  |  |  |  |  |  |  |
2023 Restructuring Plan | Life Sciences Lease Market |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-cash impairment charges |  |  |  | $ 9,100 |  |  |  |  |  |  |  |  |  |
2023 Restructuring Plan | Property, Plant and Equipment |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-cash impairment charges |  |  |  |  |  |  |  | $ 1,200 |  |  |  |  |  |
2023 Restructuring Plan | Office and Laboratory Space | Mission Bay Facility |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-cash impairment charges |  |  |  |  |  | $ 11,500 |  |  |  |  | $ 20,600 |  |  |
Measurement Input, Market Participant Subtenant Borrowing Rate |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Operating lease, measurement input |  |  |  |  |  | 7.90% |  |  | 6.40% |  |  |  |  |
Measurement Input, Market Participant Subtenant Borrowing Rate | 2023 Restructuring Plan |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Sublease income, measurement input |  |  |  | 8.70% | 8.50% |  |  |  |  |  |  |  |  |
Employee Severance |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring, impairment, and costs of terminated program |  |  |  | $ 535 | $ 1,943 | $ 5,483 |  |  |  |  |  |  |  |
Payments during the period |  | $ 3,300 |  | 887 | 6,624 | 3,299 |  |  |  |  |  |  |  |
Employee Severance | 2022 Restructuring Plan |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Workforce termination, percentage |  |  | 70.00% |  |  |  |  |  |  |  |  |  |  |
Restructuring, impairment, and costs of terminated program |  |  |  | 0 | 0 | 0 |  |  |  |  |  |  |  |
Payments during the period |  |  |  | 0 | 0 | 3,299 |  |  |  |  |  |  |  |
Employee Severance | 2023 Restructuring Plan |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Workforce termination, percentage | 60.00% |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring, impairment, and costs of terminated program |  |  |  | 535 | 1,943 | 5,483 |  |  |  |  |  |  | $ 30,900 |
Payments during the period |  |  |  | $ 887 | $ 6,624 | $ 0 |  |  |  |  |  |  |  |

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