<SEC-DOCUMENT>0001085146-23-002570.txt : 20230707
<SEC-HEADER>0001085146-23-002570.hdr.sgml : 20230707
<ACCEPTANCE-DATETIME>20230707132841
ACCESSION NUMBER:		0001085146-23-002570
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20230707
DATE AS OF CHANGE:		20230707

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			NEKTAR THERAPEUTICS
		CENTRAL INDEX KEY:			0000906709
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				943134940
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-45385
		FILM NUMBER:		231076202

	BUSINESS ADDRESS:	
		STREET 1:		455 MISSION BAY BOULEVARD SOUTH
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94158
		BUSINESS PHONE:		4154825300

	MAIL ADDRESS:	
		STREET 1:		455 MISSION BAY BOULEVARD SOUTH
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94158

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	INHALE THERAPEUTIC SYSTEMS INC
		DATE OF NAME CHANGE:	19980723

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	INHALE THERAPEUTIC SYSTEMS
		DATE OF NAME CHANGE:	19940303

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PRIMECAP MANAGEMENT CO/CA/
		CENTRAL INDEX KEY:			0000763212
		IRS NUMBER:				953868081

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		177 EAST COLORADO BLVD.
		STREET 2:		11TH FLOOR
		CITY:			PASADENA
		STATE:			CA
		ZIP:			91105
		BUSINESS PHONE:		6263049222

	MAIL ADDRESS:	
		STREET 1:		177 EAST COLORADO BLVD.
		STREET 2:		11TH FLOOR
		CITY:			PASADENA
		STATE:			CA
		ZIP:			91105
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>nktra14_70723.htm
<DESCRIPTION>PRIMECAP MANAGEMENT CO/CA/
<TEXT>

<html>
<head>
    <title>nktra14_70723.htm</title>
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<body>

    <div style="font-family: Georgia,'Times New Roman',Times,serif; font-size: 10pt; width: 8.2in;">
        <div>
            <div style="text-align: center; font-size: 12pt; font-weight: bold;">
                <div style="margin: auto;">UNITED STATES</div>
                <div style="margin: auto;">SECURITIES AND EXCHANGE COMMISSION</div>
                <div style="font-size: 11pt;">Washington, D.C. 20549</div>
                <div style="padding: 1em 0;">SCHEDULE 13G</div>
                <div style="padding: 1em 0; font-size: 11pt;">
                    <div>Under the Securities Exchange Act of 1934</div>

                    <div>(Amendment No. 14)*</div>

                </div>
                <div style="padding: 1em 0;">
                    <div style="text-decoration: underline;">Nektar Therapeutics</div>
                    <div style="font-weight: normal; font-size: 11pt;">(Name of Issuer)</div>
                </div>
                <div style="padding: 1em 0;">
                    <div style="text-decoration: underline;">COM</div>
                    <div style="font-weight: normal; font-size: 11pt;">(Title of Class of Securities)</div>
                </div>
                <div style="padding: 1em 0;">
                    <div style="text-decoration: underline;">640268108</div>
                    <div style="font-weight: normal; font-size: 11pt;">(CUSIP Number)</div>
                </div>
                <div style="padding: 1em 0;">
                    <div style="text-decoration: underline;">June 30, 2023</div>
                    <div style="font-weight: normal; font-size: 11pt;">(Date of Event which Requires Filing of this Statement)</div>
                </div>
            </div>
            <div style="padding: 1em 0;">
                Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
            </div>
            <div style="padding: 1em 0; text-align: center;">
                <div style="display: inline-block; text-align: left; margin: 0 auto;">
                    <div>[X] Rule 13d-1(b)</div>
                    <div>[&nbsp;&nbsp;&nbsp;] Rule 13d-1(c)</div>
                    <div>[&nbsp;&nbsp;&nbsp;] Rule 13d-1(d)</div>
                </div>
            </div>
            <div style="padding: 1em 0;">
                * The remainder of this cover page shall be filled out for a reporting person's initial filing on
				this form with respect to the subject class of securities, and for any subsequent amendment
				containing information which would alter the disclosures provided in a prior cover page.
            </div>
            <div style="padding: 1em 0;">
                The information required in the remainder of this cover page shall not be deemed to be "filed"
				for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject
				to the liabilities of that section of the Act but shall be subject	to all other provisions of the
				Act (however, see Instructions).
            </div>
        </div>

                <div style="page-break-before: always; margin-top: 4em;">
                    <div style="font-weight: bold; border: solid 1px black; margin: 1ex 0; padding: 1ex 2em; width: 14em;">CUSIP No.: 640268108</div>
                    <table border="0" cellpadding="5" style="font-size: 10pt; width: 100%; border-collapse: collapse;">
                        <tr>
                            <td style="line-height: 1px; width: 5%;">&nbsp;</td>
                            <td style="line-height: 1px; width: 10%;">&nbsp;</td>
                            <td style="line-height: 1px; width: 5%;">&nbsp;</td>
                            <td style="line-height: 1px; width: 80%;">&nbsp;</td>
                        </tr>
                        <tr>
                            <td style="border: solid 1px; text-align: center; vertical-align: top;">1</td>
                            <td colspan="3" style="border: solid 1px;">
                                <div style="margin-bottom: 1em;">
                                    <div style="font-weight: bold;">NAME OF REPORTING PERSON</div>
                                    <div>PRIMECAP Management Company</div>
                                </div>
                                <div>
                                    <div style="font-weight: bold;">I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (ENTITIES ONLY)</div>
                                    <div>95-3868081</div>
                                </div>
                            </td>
                        </tr>
                        <tr>
                            <td style="border: solid 1px; text-align: center; vertical-align: top;">2</td>
                            <td colspan="3" style="border: solid 1px;">
                                <div style="font-weight: bold;">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP</div>
                                <div>(a)  [&nbsp;&nbsp;&nbsp;]</div>
                                <div>(b)  [&nbsp;&nbsp;&nbsp;]</div>
                            </td>
                        </tr>
                        <tr>
                            <td style="border: solid 1px; text-align: center; vertical-align: top;">3</td>
                            <td colspan="3" style="font-weight: bold;">SEC USE ONLY</td>
                        </tr>
                        <tr>
                            <td style="border: solid 1px; text-align: center; vertical-align: top;">4</td>
                            <td colspan="3" style="border: solid 1px black;">
                                <div style="font-weight: bold;">CITIZENSHIP OR PLACE OF ORGANIZATION</div>
                                <div>177 E. Colorado Blvd., 11th Floor, Pasadena, CA 91105</div>
                            </td>
                        </tr>
                        <tr>
                            <td rowspan="4" colspan="2" style="width: 10%; text-align: center; border: solid 1px; font-weight: bold;">NUMBER OF SHARES BENEFICIALLY OWNED	BY EACH REPORTING PERSON WITH</td>
                            <td style="text-align: center; border: solid 1px; vertical-align: top;">5</td>
                            <td style="border: solid 1px black;">
                                <div style="font-weight: bold;">SOLE VOTING POWER</div>
                                <div>8,106,976</div>
                            </td>
                        </tr>
                        <tr style="border: solid 1px black;">
                            <td style="text-align: center; border: solid 1px; vertical-align: top;">6</td>
                            <td style="border: solid 1px black;">
                                <div style="font-weight: bold;">SHARED VOTING POWER</div>
                                <div>0</div>
                            </td>
                        </tr>
                        <tr style="border: solid 1px black;">
                            <td style="text-align: center; border: solid 1px; vertical-align: top;">7</td>
                            <td style="border: solid 1px black;">
                                <div style="font-weight: bold;">SOLE DISPOSITIVE POWER</div>
                                <div>8,149,876</div>
                            </td>
                        </tr>
                        <tr>
                            <td style="text-align: center; border: solid 1px; vertical-align: top;">8</td>
                            <td style="border: solid 1px black;">
                                <div style="font-weight: bold;">SHARED DISPOSITIVE POWER</div>
                                <div>0</div>
                            </td>
                        </tr>
                        <tr>
                            <td style="border: solid 1px; text-align: center; vertical-align: top;">9</td>
                            <td colspan="3" style="border: solid 1px black;">
                                <div style="font-weight: bold;">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON</div>
                                <div>8,149,876</div>
                            </td>
                        </tr>
                        <tr>
                            <td style="border: solid 1px; text-align: center; vertical-align: top;">10</td>
                            <td colspan="3" style="border: solid 1px;">
                                <div style="font-weight: bold;">CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES</div>
                                [&nbsp;&nbsp;&nbsp;]
                            </td>
                        </tr>
                        <tr>
                            <td style="border: solid 1px; text-align: center; vertical-align: top;">11</td>
                            <td colspan="3" style="border: solid 1px;">
                                <div style="font-weight: bold;">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)</div>
                                <div>4.31%</div>
                            </td>
                        </tr>
                        <tr>
                            <td style="border: solid 1px; text-align: center; vertical-align: top;">12</td>
                            <td colspan="3" style="border: solid 1px;">
                                <div style="font-weight: bold;">TYPE OF REPORTING PERSON</div>
                                <div>IA</div>
                            </td>
                        </tr>
                    </table>
                </div>

        <div style="page-break-before: always; margin-top: 4em;">
            <div style="font-weight: bold; border: solid 1px black; margin: 1ex 0; padding: 1ex 2em; width: 14em;">CUSIP No.: 640268108</div>
            <table cellpadding="5" cellspacing="0" border="0" style="font-size: 10pt; width: 100%; margin: 2em auto; border: 0; border-collapse: collapse;">
                <tr>
                    <td valign="top" style="white-space: nowrap;"><strong>ITEM 1(a).</strong></td>
                    <td colspan="2" valign="top">
                        <strong>NAME OF ISSUER:</strong>
                        <div style="padding: 1ex 0;">
                            Nektar Therapeutics
                        </div>
                    </td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;"><strong>ITEM 1(b).</strong></td>
                    <td colspan="2" valign="top">
                        <strong>ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:</strong>
                        <div style="padding: 1ex 0;">
                            455 Mission Bay Blvd. South, San Francisco, CA 94158
                        </div>
                    </td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;"><strong>ITEM 2(a).</strong></td>
                    <td colspan="2" valign="top">
                        <strong>NAME OF PERSON FILING:</strong>
                        <div style="padding: 1ex 0;">
                            PRIMECAP Management Company
                        </div>
                    </td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;"><strong>ITEM 2(b).</strong></td>
                    <td colspan="2" valign="top">
                        <strong>ADDRESS OF PRINCIPAL BUSINESS OFFICE OR, IF NONE, RESIDENCE:</strong>
                        <div style="padding: 1ex 0;">
                            177 E. Colorado Blvd., 11th Floor, Pasadena, CA 91105
                        </div>
                    </td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;"><strong>ITEM 2(c).</strong></td>
                    <td colspan="2" valign="top">
                        <strong>CITIZENSHIP:</strong>
                        <div style="padding: 1ex 0;">
                            U.S.A.
                        </div>
                    </td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;"><strong>ITEM 2(d).</strong></td>
                    <td colspan="2" valign="top">
                        <strong>TITLE OF CLASS OF SECURITIES:</strong>
                        <div style="padding: 1ex 0;">
                            COM
                        </div>
                    </td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;"><strong>ITEM 2(e).</strong></td>
                    <td colspan="2" valign="top">
                        <strong>CUSIP NUMBER:</strong>
                        <div style="padding: 1ex 0;">
                            640268108
                        </div>
                    </td>
                </tr>
                <tr>
                    <td rowspan="13" valign="top" style="white-space: nowrap;"><strong>ITEM 3.</strong></td>
                    <td colspan="2" valign="top">
                        <strong>IF THIS STATEMENT IS FILED PURSUANT TO SECTION 240.13d-1(b), or 13d-2(b) or (c)	CHECK WHETHER THE PERSON FILING IS A:</strong>
                    </td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap; width: 11%;">
                        <div style="width: 30px; display: inline-block;">(a)</div>
                        [ ]</td>
                    <td valign="top">Broker or dealer registered under Section 15 of the Act (15 U.S.C. 78c);</td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;">
                        <div style="width: 30px; display: inline-block;">(b)</div>
                        [ ]</td>
                    <td valign="top">Bank as defined in Section 3(a)(6) of the Act (15 U.S.C. 78c);</td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;">
                        <div style="width: 30px; display: inline-block;">(c)</div>
                        [ ]</td>
                    <td valign="top">Insurance company as defined in Section 3(a)(19) of the Act (15 U.S.C. 78c);</td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;">
                        <div style="width: 30px; display: inline-block;">(d)</div>
                        [ ]</td>
                    <td valign="top">Investment company registered under Section 8 of the Investment Company Act of 1940 (15 U.S.C 80a-8);</td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;">
                        <div style="width: 30px; display: inline-block;">(e)</div>
                        [X]</td>
                    <td valign="top">An investment adviser in accordance with 240.13d-1(b)(1)(ii)(E);</td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;">
                        <div style="width: 30px; display: inline-block;">(f)</div>
                        [ ]</td>
                    <td valign="top">An employee benefit plan or endowment fund in accordance with 240.13d-1(b)(1)(ii)(F);</td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;">
                        <div style="width: 30px; display: inline-block;">(g)</div>
                        [ ]</td>
                    <td valign="top">A parent holding company or control person in accordance with 240.13d-1(b)(1)(ii)(G);</td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;">
                        <div style="width: 30px; display: inline-block;">(h)</div>
                        [ ]</td>
                    <td valign="top">A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);</td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;">
                        <div style="width: 30px; display: inline-block;">(i)</div>
                        [ ]</td>
                    <td valign="top">A church plan that is excluded from the definition of an investment company under Section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);</td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;">
                        <div style="width: 30px; display: inline-block;">(j)</div>
                        [ ]</td>
                    <td valign="top">A non-U.S. institution in accordance with 240.13d-1(b)(1)(ii)(J);</td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;">
                        <div style="width: 30px; display: inline-block;">(k)</div>
                        [ ]</td>
                    <td valign="top">Group, in accordance with 240.13d-1(b)(1)(ii)(K). If filing as a non-U.S. institution in accordance with 240.13d1(b)(1)(ii)(J), please specify the type of institution:
						          <div></div>
                    </td>
                </tr>
                <tr>
                    <td valign="top" colspan="2">
						          <div style="margin-bottom:1em;"></div>
                    </td>
                </tr>
                <tr>
                    <td rowspan="15" valign="top" style="white-space: nowrap;"><strong>ITEM 4.</strong></td>
                    <td colspan="2" valign="top">
                        <strong>OWNERSHIP</strong>
                    </td>
                </tr>
                <tr>
                    <td colspan="2" valign="top">

                    </td>
                </tr>
                <tr>
                    <td colspan="2" valign="top"><strong>(a) Amount beneficially owned:</strong></td>
                </tr>
                <tr>
                    <td colspan="2" valign="top">8,149,876</td>
                </tr>
                <tr>
                    <td colspan="2" valign="top"><strong>(b) Percent of class:</strong></td>
                </tr>
                <tr>
                    <td colspan="2" valign="top">4.31%</td>
                </tr>
                <tr>
                    <td colspan="2" valign="top"><strong>(c) Number of shares as to which the person has:</strong></td>
                </tr>
                <tr>
                    <td colspan="2" valign="top" style="padding-left: 28px;">(i) sole power to vote or to direct the vote:</td>
                </tr>
                <tr>
                    <td colspan="2" valign="top" style="padding-left: 28px;">8,106,976</td>
                </tr>
                <tr>
                    <td colspan="2" valign="top" style="padding-left: 28px;">(ii) shared power to vote or to direct the vote:</td>
                </tr>
                <tr>
                    <td colspan="2" valign="top" style="padding-left: 28px;">0</td>
                </tr>
                <tr>
                    <td colspan="2" valign="top" style="padding-left: 28px;">(iii) sole power to dispose or direct the disposition of:</td>
                </tr>
                <tr>
                    <td colspan="2" valign="top" style="padding-left: 28px;">8,149,876</td>
                </tr>
                <tr>
                    <td colspan="2" valign="top" style="padding-left: 28px;">(iv) shared power to dispose or to direct the disposition of:</td>
                </tr>
                <tr>
                    <td colspan="2" valign="top" style="padding-left: 28px;">0</td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;"><strong>ITEM 5.</strong></td>
                    <td colspan="2" valign="top">
                        <strong>OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS:</strong>
                        <div style="padding: 1ex 0;">
                            If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following
						    [X].
                        </div>
                    </td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;"><strong>ITEM 6.</strong></td>
                    <td colspan="2" valign="top">
                        <strong>OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON:</strong>
                        <div style="padding: 1ex 0;">
                            Not Applicable
                        </div>
                    </td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;"><strong>ITEM 7.</strong></td>
                    <td colspan="2" valign="top">
                        <strong>IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY:</strong>
                        <div style="padding: 1ex 0;">
                            Not Applicable
                        </div>
                    </td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;"><strong>ITEM 8.</strong></td>
                    <td colspan="2" valign="top">
                        <strong>IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP:</strong>
                        <div style="padding: 1ex 0;">
                            Not Applicable
                        </div>
                    </td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;"><strong>ITEM 9.</strong></td>
                    <td colspan="2" valign="top">
                        <strong>NOTICE OF DISSOLUTION OF GROUP:</strong>
                        <div style="padding: 1ex 0;">
                            Not Applicable
                        </div>
                    </td>
                </tr>
                <tr>
                    <td valign="top" style="white-space: nowrap;"><strong>ITEM 10.</strong></td>
                    <td colspan="2" valign="top">
                        <strong>CERTIFICATION:</strong>
                        <div style="padding: 1ex 0;">
                            By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.
                        </div>
                    </td>
                </tr>
            </table>
        </div>
        <div style="page-break-before: always; margin-top: 4em;">
            <div style="font-weight: bold; border: solid 1px black; margin: 1ex 0; padding: 1ex 2em; width: 14em;">CUSIP No.: 640268108</div>
            <div style="padding: 1em 0; text-align: center; font-size: 12pt; font-weight: bold;">SIGNATURE</div>
            <div style="padding: 1em 0 2em 0; font-size: 8pt; text-align: center;">After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.</div>

                    <div style="page-break-inside: avoid; padding-bottom: 1em">
                        <table style="width: 100%; border: 0; font-size: 9pt;" border="0" cellpadding="0" cellspacing="0">
                            <tr>
                                <td valign="top" style="width: 30%;">July 07 2023</td>
                                <td valign="top" style="width: 80%;">
                                    <div style="width: 70%; margin-bottom: 1ex;">PRIMECAP Management Company</div>
                                    <div style="width: 70%; margin-bottom: 1ex;">
                                        <div style="display: inline-block; width: 12%;">By:</div>
                                        <div style="display: inline-block; width: 86%; border-bottom: solid 2px black;">/s/ Julietta Martikyan
</div>
                                    </div>
                                    <div style="width: 70%; margin-bottom: 1ex;">
                                        <div style="display: inline-block; width: 12%;">Name:</div>
                                        <div style="display: inline-block; width: 86%;">Julietta Martikyan</div>
                                    </div>
                                    <div style="width: 70%; margin-bottom: 1ex;">
                                        <div style="display: inline-block; width: 12%;">Title:</div>
                                        <div style="display: inline-block; width: 86%;">Director of Compliance and Administration</div>
                                    </div>
                                </td>
                            </tr>
                        </table>
                    </div>

            <div style="padding-top: 1em; font-size: 9pt;">Attention &mdash; Intentional misstatements or omissions of fact constitute Federal criminal violations (See 18 U.S.C. 1001).</div>

        </div>

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</SEC-DOCUMENT>
