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Restructuring, Impairment and Costs of Terminated Program - Narrative (Details) - USD ($) $ in Thousands | 1 Months Ended | 3 Months Ended | 9 Months Ended | 12 Months Ended | 21 Months Ended
--- | --- | --- | --- | --- | ---
Jan. 31, 2024 | Jun. 30, 2023 | Jan. 31, 2023 | Apr. 30, 2022 | Dec. 31, 2023 | Sep. 30, 2023 | Jun. 30, 2023 | Mar. 31, 2023 | Dec. 31, 2022 | Sep. 30, 2022 | Jun. 30, 2022 | Mar. 31, 2022 | Dec. 31, 2022 | Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2023
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-cash impairment charges |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 36,962 | $ 67,875 |  |
Impairment of goodwill |  |  |  |  |  |  |  | $ 76,500 |  |  |  |  |  | 76,501 | 0 | $ 0 |
Nektar 214 | Bristol-Myers Squibb Company |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Reimbursement of expenses |  |  |  |  |  |  |  |  |  |  |  |  | $ 20,800 |  | 20,800 |  |
Nektar 214 | Research and Development Expense | Bristol-Myers Squibb Company |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Reimbursement of expenses |  |  |  |  |  |  |  |  |  |  |  | $ 24,900 |  |  | 45,700 | $ 101,500 |
2022 Restructuring Plan |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-cash impairment charges |  |  |  |  | $ 0 | $ (1,467) | $ (13,261) | 0 | $ (12,361) | $ (1,200) | $ (52,200) |  |  |  |  |  | $ (80,489)
Contract termination and other costs included in accrued expenses |  |  |  |  | $ 3,000 |  |  |  |  |  |  |  |  | 3,000 |  |  | $ 3,000
2023 Restructuring Plan | Life Sciences Lease Market |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-cash impairment charges |  |  |  |  |  | $ 9,100 |  |  |  |  |  |  |  |  |  |  |
2023 Restructuring Plan | Office and Laboratory Space | Mission Bay Facility |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-cash impairment charges |  |  |  |  |  |  |  | $ 11,500 |  |  |  |  |  | 20,600 |  |  |
Measurement Input, Market Participant Subtenant Borrowing Rate | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Operating lease, measurement input |  |  |  |  |  | 8.70% |  |  |  |  |  |  |  |  |  |  |
Measurement Input, Market Participant Subtenant Borrowing Rate | Minimum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Operating lease, measurement input |  |  |  |  |  |  |  |  |  |  | 6.40% |  |  |  |  |  |
Employee Severance |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring, impairment, and costs of terminated program |  |  |  |  |  |  |  |  |  |  |  |  |  | 7,885 | 30,904 |  |
Payments during the period |  |  | $ 3,300 |  |  |  |  |  |  |  |  |  |  | 10,988 | 27,605 |  |
Employee Severance | 2022 Restructuring Plan |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Workforce termination, percentage |  |  |  | 70.00% |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring, impairment, and costs of terminated program |  |  |  |  |  |  |  |  |  |  |  |  |  | 0 | 30,904 |  |
Payments during the period |  |  |  |  |  |  |  |  |  |  |  |  |  | 3,299 | 27,605 |  |
Employee Severance | 2023 Restructuring Plan |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Workforce termination, percentage |  | 60.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring, impairment, and costs of terminated program |  |  |  |  |  |  |  |  |  |  |  |  |  | 7,885 | 0 |  |
Payments during the period |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 7,689 | $ 0 |  |
Employee Severance | 2023 Restructuring Plan | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Payments during the period | $ 200 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

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