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Liabilities Related to the Sales of Future Royalties - Additional Information (Details) $ in Thousands |  |  |  | 3 Months Ended | 12 Months Ended
--- | --- | --- | --- | --- | ---
Mar. 01, 2024 USD ($) | Dec. 16, 2020 USD ($) | Feb. 24, 2012 USD ($) | Dec. 31, 2021 USD ($) | Dec. 31, 2023 USD ($) | Dec. 31, 2022 USD ($) | Dec. 31, 2021 USD ($)
Liability Related to the Sale of Future Royalties [Line Items] |  |  |  |  |  |  |
Non-cash loss on revaluation of liability related to the sale of future royalties |  |  |  |  | $ 0 | $ 0 | $ 24,410
2012 Purchase and Sale Agreement |  |  |  |  |  |  |
Liability Related to the Sale of Future Royalties [Line Items] |  |  |  |  |  |  |
Proceeds from sale of royalty rights |  |  | $ 124,000 |  |  |  |
2012 Purchase and Sale Agreement | Future Royalties |  |  |  |  |  |  |
Liability Related to the Sale of Future Royalties [Line Items] |  |  |  |  |  |  |
Fair value of liabilities |  |  |  |  | $ 84,700 |  |
Non-cash loss on revaluation of liability related to the sale of future royalties |  |  |  | $ 23,500 |  |  |
Transaction costs related to revised royalty payments |  |  |  | $ 900 |  |  |
2020 Purchase and Sale Agreement |  |  |  |  |  |  |
Liability Related to the Sale of Future Royalties [Line Items] |  |  |  |  |  |  |
Proceeds from sale of royalty rights |  | $ 150,000 |  |  |  |  |
Payment of transaction related to purchase and sale agreement |  | 210,000 |  |  |  |  |
Payment of transaction related to purchase and sale agreement if threshold is not achieved |  | $ 240,000 |  |  |  |  |
2020 Purchase and Sale Agreement | Subsequent Event |  |  |  |  |  |  |
Liability Related to the Sale of Future Royalties [Line Items] |  |  |  |  |  |  |
Amount exchanged to remove cap on royalties | $ 15,000 |  |  |  |  |  |
2020 Purchase and Sale Agreement | Measurement Input, Discount Rate |  |  |  |  |  |  |
Liability Related to the Sale of Future Royalties [Line Items] |  |  |  |  |  |  |
Royalties liability, measurement input |  |  |  |  | 0.17 |  |
2020 Purchase and Sale Agreement | Measurement Input, Interest Rate |  |  |  |  |  |  |
Liability Related to the Sale of Future Royalties [Line Items] |  |  |  |  |  |  |
Royalties liability, measurement input |  |  |  |  | 0.30 |  |
Pursuant to the 2012 Purchase and Sale Agreement |  |  |  |  |  |  |
Liability Related to the Sale of Future Royalties [Line Items] |  |  |  |  |  |  |
Payment made for milestone not achieved year one |  |  |  |  |  | $ 10,000 |
Payment made for milestone not achieved year two |  |  |  |  | $ 10,000 |  |

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