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Consolidated Financial Statement Details (Tables) | 12 Months Ended
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Dec. 31, 2023
Inventory Disclosure [Abstract] |
Schedule of Inventory | Inventory Inventory consists of the following (in thousands):
|  | December 31, |
|  | 2023 |  |  | 2022 |
Raw materials |  | $ | 1,861 |  |  | $ | 2,575 |
Work-in-process |  |  | 12,880 |  |  |  | 10,749 |
Finished goods |  |  | 1,360 |  |  |  | 5,878 |
Total inventory |  | $ | 16,101 |  |  | $ | 19,202 |
Schedule of Other Current Assets | Other Current Assets Other current assets consists of the following (in thousands):
|  | December 31, |
|  | 2023 |  |  | 2022 |
Prepaid research and development expenses |  | $ | 4,325 |  |  | $ | 7,398 |
Non-trade receivables and other |  |  | 1,047 |  |  |  | 2,423 |
Other prepaid expenses |  |  | 4,407 |  |  |  | 5,987 |
Total other current assets |  | $ | 9,779 |  |  | $ | 15,808 |
Schedule of Property, Plant and Equipment | Property, Plant and Equipment Property, plant and equipment consists of the following (in thousands):
|  | December 31, |
|  | 2023 |  |  | 2022 |
Building and leasehold improvements |  | $ | 43,184 |  |  | $ | 74,889 |
Laboratory equipment |  |  | 14,537 |  |  |  | 24,243 |
Computer equipment and software |  |  | 22,438 |  |  |  | 26,205 |
Manufacturing equipment |  |  | 24,315 |  |  |  | 25,052 |
Furniture, fixtures, and other |  |  | 541 |  |  |  | 4,263 |
Depreciable property, plant and equipment at cost |  |  | 105,015 |  |  |  | 154,652 |
Less: accumulated depreciation |  |  | (86,898 | ) |  |  | (124,731 | )
Depreciable property, plant and equipment, net |  |  | 18,117 |  |  |  | 29,921 |
Construction-in-progress |  |  | 739 |  |  |  | 2,530 |
Property, plant and equipment, net |  | $ | 18,856 |  |  | $ | 32,451 |
We recorded the gains and losses as follows (in thousands):
|  | Year Ended December 31, |
|  | 2023 |  | 2022 |
Proceeds from sales |  | $ | 1,245 |  | $ | 13,196 |
Net book value of assets |  |  | 2,545 |  |  | 9,870 |
Total (gain) loss on sale or disposal of other property, plant and equipment, net |  | $ | 1,300 |  | $ | (3,326 | )
Schedule of Goodwill | Goodwill The following is a reconciliation of the change in our goodwill for the year ended December 31, 2023 (in thousands):
|  | Year Ended December 31, 2023 |
Goodwill – beginning balance |  | $ | 76,501 |
Impairment of goodwill |  |  | (76,501 | )
Goodwill – ending balance |  | $ | — |
Schedule of Accred Expenses | Accrued Expenses Accrued expenses consist of the following (in thousands):
|  | December 31, |
|  | 2023 |  |  | 2022 |
Accrued compensation |  | $ | 5,553 |  |  | $ | 9,582 |
Accrued clinical trial expenses |  |  | 4,321 |  |  |  | 12,262 |
Liability to collaboration partners |  |  | 2,678 |  |  |  | 3,808 |
Accrued contract termination costs |  |  | 3,020 |  |  |  | 3,902 |
Other accrued expenses |  |  | 6,590 |  |  |  | 7,003 |
Total accrued expenses |  | $ | 22,162 |  |  | $ | 36,557 |
Schedule of Accumulated Other Comprehensive Income (Loss) | Accumulated Other Comprehensive Income (Loss) The following table summarizes the changes in accumulated other comprehensive income (loss) by component (in thousands):
|  | Foreign currency translation |  |  | Available-for-sale securities |  |  | Accumulated Other Comprehensive Income |
Balance at December 31, 2022 |  | $ | (5,131 | ) |  | $ | (1,776 | ) |  | $ | (6,907 | )
Foreign currency translation gain |  |  | 62 |  |  |  | — |  |  |  | 62 |
Unrealized gain on available-for-sale securities |  |  | — |  |  |  | 1,826 |  |  |  | 1,826 |
Reclassification adjustments to income |  |  | 5,099 |  |  |  | — |  |  |  | 5,099 |
Balance at December 31, 2023 |  | $ | 30 |  |  | $ | 50 |  |  | $ | 80 |

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