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Organization and Summary of Significant Accounting Policies (Details) - USD ($) shares in Millions | 1 Months Ended | 12 Months Ended
--- | --- | ---
Jun. 30, 2023 | Apr. 30, 2022 | Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |
Cash and investments in marketable securities |  |  | $ 329,441,000 | $ 504,977,000 |
Total revenue |  |  | 90,122,000 | $ 92,055,000 | $ 101,907,000
Accounts receivable, credit loss expense (reversal) |  |  | $ 0 |  |
Employee Severance | 2022 Restructuring Plan |  |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |
Workforce termination, percentage |  | 70.00% |  |  |
Employee Severance | 2023 Restructuring Plan |  |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |
Workforce termination, percentage | 60.00% |  |  |  |
Stock Options, RSUs and PSUs |  |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |
Weighted average antidilutive securities excluded from computation of earnings per share (in shares) |  |  | 20.4 | 21.2 | 18.4
Cash And NonCash Royalties |  |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |
Total revenue |  |  | $ 68,900,000 | $ 69,800,000 | $ 77,700,000
Buildings |  |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |
Property and equipment estimated useful lives |  |  | 20 years |  |
Minimum | Manufacturing equipment |  |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |
Property and equipment estimated useful lives |  |  | 3 years |  |
Maximum | Manufacturing equipment |  |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |
Property and equipment estimated useful lives |  |  | 10 years |  |

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