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Income Taxes - Schedule of Income Tax Provision Related to Continuing Operations (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
Income Tax Disclosure [Abstract]
Income tax benefit at federal statutory rate	$ (58,013)	$ (76,647)	$ (109,889)
Research credits	(1,192)	(987)	(4,727)
Change in valuation allowance	35,033	51,108	97,914
Expiration of net operating loss carryforwards	312	12,348	286
Stock-based compensation	8,919	15,778	6,627
Non-cash interest expense on liability related to sales of future royalties	5,320	6,071	9,936
Non-cash royalty revenue related to sales of future royalties	(7,838)	(7,112)	(7,891)
Loss on revaluation of liability related to the sale of future royalties	0	0	4,940
Impairment of goodwill	16,065	0	0
Other	1,194	2,656	3,361
Provision (benefit) for income taxes	$ (200)	$ 3,215	$ 557

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Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

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