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Liabilities Related to the Sales of Future Royalties (Tables) | 12 Months Ended
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Dec. 31, 2024
Liability Related To Sale Of Potential Future Royalties [Abstract] |
Schedule of Liability Related to Potential Future Royalties | The following table shows the activity within the liability account of each arrangement (in thousands):
|  | Year-Ended December 31, 2024 |  |  | Period from inception to December 31, 2024 |
|  | 2012 Purchase and Sale Agreement |  |  | 2020 Purchase and Sale Agreement |  |  | Total |  |  | 2012 Purchase and Sale Agreement |  |  | 2020 Purchase and Sale Agreement |  |  | Total |
Liabilities related to the sales of future royalties—beginning balance |  | $ | 24,217 |  |  | $ | 89,657 |  |  | $ | 113,874 |  |  | $ | — |  |  | $ | — |  |  | $ | — |
Royalty monetization proceeds |  |  | — |  |  |  | 15,000 |  |  |  | 15,000 |  |  |  | 124,000 |  |  |  | 165,000 |  |  |  | 289,000 |
Non-cash royalty revenue |  |  | (26,881 | ) |  |  | (37,386 | ) |  |  | (64,267 | ) |  |  | (380,728 | ) |  |  | (155,705 | ) |  |  | (536,433 | )
Non-cash interest expense |  |  | 9,861 |  |  |  | 18,251 |  |  |  | 28,112 |  |  |  | 250,403 |  |  |  | 76,227 |  |  |  | 326,630 |
Payments to RPI |  |  | — |  |  |  | — |  |  |  | — |  |  |  | (10,000 | ) |  |  | — |  |  |  | (10,000 | )
Loss on revaluation of liability related to the sale of future royalties |  |  | — |  |  |  | — |  |  |  | — |  |  |  | 23,522 |  |  |  | — |  |  |  | 23,522 |
Liabilities related to the sales of future royalties – ending balance |  |  | 7,197 |  |  |  | 85,522 |  |  |  | 92,719 |  |  |  | 7,197 |  |  |  | 85,522 |  |  |  | 92,719 |
Less: unamortized transaction costs |  |  | — |  |  |  | (943 | ) |  |  | (943 | ) |  |  | — |  |  |  | (943 | ) |  |  | (943 | )
Liabilities related to the sales of future royalties, net |  | $ | 7,197 |  |  | $ | 84,579 |  |  | $ | 91,776 |  |  | $ | 7,197 |  |  | $ | 84,579 |  |  | $ | 91,776 |

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