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CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
shares in Thousands, $ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Revenue:    
Total revenue $ 98,427 $ 90,122
Operating costs and expenses:    
Cost of goods sold 30,686 33,768
Research and development (including $277 and $0 from a related party) 120,908 114,162
General and administrative 76,751 77,417
Restructuring and impairment 15,670 51,958
Impairment of goodwill 0 76,501
Gain on sale of the Huntsville manufacturing facility (40,390) 0
Total operating costs and expenses 203,625 353,806
Loss from operations (105,198) (263,684)
Non-operating income (expense):    
Non-cash interest expense on liabilities related to the sales of future royalties (28,112) (25,334)
Interest income 14,500 19,009
Other income (expense), net (390) (6,247)
Total non-operating income (expense), net (14,002) (12,572)
Loss before provision for income taxes (119,200) (276,256)
Provision (benefit) for income taxes (239) (200)
Net loss $ (118,961) $ (276,056)
Basic net loss per share (in dollars per share) $ (0.58) $ (1.45)
Diluted net loss per share (in dollars per share) $ (0.58) $ (1.45)
Weighted average shares outstanding used in computing basic net loss per share (in shares) 205,661 190,001
Weighted average shares outstanding used in computing diluted net loss per share (in shares) 205,661 190,001
Product sales    
Revenue:    
Total revenue $ 33,563 $ 20,681
Non-cash royalty revenue related to the sales of future royalties    
Revenue:    
Total revenue 64,267 68,921
License, collaboration and other revenue    
Revenue:    
Total revenue $ 597 $ 520