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Restructuring and Impairment - Narrative (Details) - USD ($)
$ in Thousands
 1 Months Ended 3 Months Ended 12 Months Ended 24 Months Ended
Jun. 30, 2023
Apr. 30, 2022
Jun. 30, 2024
Mar. 31, 2024
Dec. 31, 2023
Sep. 30, 2023
Jun. 30, 2023
Mar. 31, 2023
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2024
2022 Restructuring Plan                      
Restructuring Cost and Reserve [Line Items]                      
Non-cash impairment charges     $ (4,429) $ 0 $ 0 $ (1,467) $ (13,261) $ 0     $ (19,157)
2022 Restructuring Plan | Third St. Facility                      
Restructuring Cost and Reserve [Line Items]                      
Non-cash impairment charges     4,400       6,200        
2022 Restructuring Plan | Mission Bay Facility                      
Restructuring Cost and Reserve [Line Items]                      
Non-cash impairment charges           1,500 $ 7,100        
2023 Restructuring Plan | Mission Bay Facility                      
Restructuring Cost and Reserve [Line Items]                      
Non-cash impairment charges     $ 3,900     $ 9,100   11,500      
Restructuring Plan                      
Restructuring Cost and Reserve [Line Items]                      
Contract termination costs included in accrued expenses         3,000       $ 2,800 $ 3,000 2,800
Contract termination costs included In other long-term liabilities         $ 2,500       6,300 2,500 $ 6,300
Measurement Input, Market Participant Subtenant Borrowing Rate | Maximum                      
Restructuring Cost and Reserve [Line Items]                      
Sublease income, measurement input                     8.70%
Measurement Input, Market Participant Subtenant Borrowing Rate | Minimum                      
Restructuring Cost and Reserve [Line Items]                      
Sublease income, measurement input                     6.20%
Employee Severance                      
Restructuring Cost and Reserve [Line Items]                      
Restructuring, impairment, and costs of terminated program                 0 7,885  
Payments during the period                 196 10,988  
Employee Severance | 2022 Restructuring Plan                      
Restructuring Cost and Reserve [Line Items]                      
Workforce termination, percentage   70.00%                  
Restructuring, impairment, and costs of terminated program                 0 0  
Payments during the period               $ 3,300 0 3,299  
Employee Severance | 2023 Restructuring Plan                      
Restructuring Cost and Reserve [Line Items]                      
Workforce termination, percentage 60.00%                    
Restructuring, impairment, and costs of terminated program                 0 $ 7,885  
Restructuring Charges, Statement of Income or Comprehensive Income [Extensible Enumeration]                   Restructuring Costs and Asset Impairment Charges  
Payments during the period       $ 200         $ 196 $ 7,689