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v3.25.1

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2025 | Mar. 31, 2024
Cash flows from operating activities: |  |
Net loss | $ (50,882) | $ (36,802)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Non-cash royalty revenue related to the sales of future royalties | (10,460) | (15,508)
Non-cash interest expense on liabilities related to the sales of future royalties | 4,974 | 5,531
Loss from equity method investment | 4,461 | 0
Stock-based compensation | 3,898 | 6,000
Depreciation and amortization expense | 426 | 1,607
Provision for net realizable value of inventory | 0 | 1,006
Amortization of premiums (discounts), net | (1,324) | (3,063)
Changes in operating assets and liabilities: |  |
Accounts receivable | 0 | (2,412)
Inventory | 0 | (1,143)
Operating leases, net | (1,813) | (2,958)
Other assets | (5,958) | (976)
Accounts payable | 6,410 | (988)
Accrued expenses | 1,215 | 1,818
Net cash used in operating activities | (49,053) | (47,888)
Cash flows from investing activities: |  |
Purchases of investments | (24,931) | (105,059)
Maturities of investments | 69,319 | 124,474
Purchases of property equipment | (2) | (157)
Payment of transaction costs and working capital adjustment from the sale of the Huntsville manufacturing facility | (697) | 0
Net cash provided by investing activities | 43,689 | 19,258
Cash flows from financing activities: |  |
Proceeds from shares issued under equity compensation plans | 7 | 3
Proceeds from issuance of pre-funded warrant | 0 | 30,000
Proceeds from sale of future royalties | 0 | 15,000
Repurchase of common stock from Bristol-Myers Squibb | 0 | (3,000)
Net cash provided by financing activities | 7 | 42,003
Effect of foreign exchange rates on cash and cash equivalents | (1) | (8)
Net increase (decrease) in cash and cash equivalents | (5,358) | 13,365
Cash and cash equivalents at beginning of period | 44,252 | 35,277
Cash and cash equivalents at end of period | $ 38,894 | $ 48,642

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