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License and Collaboration Agreements - Additional Information (Details) |  |  | 1 Months Ended | 3 Months Ended | 9 Months Ended | 12 Months Ended |
--- | --- | --- | --- | --- | --- | --- | ---
Feb. 12, 2024 USD ($) shares | Jul. 23, 2017 USD ($) | Apr. 30, 2018 USD ($) shares | Sep. 30, 2025 USD ($) Milestones | Sep. 30, 2024 USD ($) | [1] | Sep. 30, 2025 USD ($) Milestones | Sep. 30, 2024 USD ($) | [1] | Dec. 31, 2023 USD ($) | Dec. 31, 2020 USD ($)
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Revenue |  |  |  | $ 11,790,000 | $ 24,124,000 | $ 33,425,000 | $ 69,252,000 |  |
Non-cash royalty revenue related to the sales of future royalties |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Revenue |  |  |  | 11,490,000 | $ 15,731,000 | 33,125,000 | $ 48,029,000 |  |
Bristol Myers Squibb Company | Purchase Agreement |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Shares issued (in shares) | shares |  |  | 552,307 |  |  |  |  |  |
Sale of stock consideration received |  |  | $ 850,000,000 |  |  |  |  |  |
Other Partner |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Potential future additional payments for development milestones |  |  |  | $ 40,000,000 |  | $ 40,000,000 |  |  |
Nektar-358 | Maximum | Eli Lilly And Company |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Potential future additional development and regulatory milestones (up to) |  | $ 250,000,000 |  |  |  |  |  |  |
Nektar 0165 | Biolojic Design Company [Member] |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Payable For Newdrug Investigle Milestone |  |  |  |  |  |  |  | $ 3,000,000 |
Number of Milestone | Milestones |  |  |  | 0 |  | 0 |  |  |
Nektar 0165 | Maximum | Biolojic Design Company [Member] |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Potential future additional payments for development milestones |  |  |  |  |  |  |  | 35,000,000 |
Payment For Development Milestones |  |  |  |  |  |  |  | $ 18,000,000 |
Bristol Myers Squibb Collaboration Agreement |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Sale of stock shares repurchased | shares | 552,307 |  |  |  |  |  |  |  |
Sale of stock repurchased cash consideration | $ 3,000,000 |  |  |  |  |  |  |  |
Nektar's | Nektar-358 |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Received upfront and milestone payment |  | $ 150,000,000 |  |  |  |  |  |  |
Nektar's | Bristol Myers Squibb Collaboration Agreement | Nektar 214 |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Upfront and milestone payments received from license agreements |  |  | $ 1,000,000,000 |  |  |  |  |  |
Nektar's | Bristol Myers Squibb Collaboration Agreement | Nektar 214 | Milestone One |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Potential future additional payments for development milestones |  |  |  |  |  |  |  |  | $ 50,000,000
[1] | All share and per share amounts have been retrospectively adjusted to reflect a one-for-fifteen reverse stock split (see Note 6).

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