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Consolidated Statements of Income - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Income Statement [Abstract]      
Product revenues $ 985,683 $ 917,600 $ 856,445
Cost of sales 674,570 622,563 580,066
Gross margin 311,113 295,037 276,379
Operating costs and expenses:      
Research and development expenses 94,515 79,583 69,211
Reimbursed research and development expenses (12,037) (6,660) (9,607)
Net research and development expenses 82,478 72,923 59,604
Acquisition transaction expenses 789 743  
Selling, general and administrative expenses 130,522 115,252 95,456
Total operating costs and expenses 213,789 188,918 155,060
Operating income 97,324 106,119 121,319
Interest expense (4,885) (3,257) (2,610)
Revaluation of derivatives loss     (1,102)
Gain on settlement of lawsuit     9,949
Foreign currency (loss) gain (23,108) 7,810 1,121
Other (loss) income (76) (109) 261
Earnings before income tax 69,255 110,563 128,938
Income tax expense 34,028 33,965 33,545
Net income $ 35,227 $ 76,598 $ 95,393
Basic earnings per share $ 0.96 $ 2.10 $ 2.65
Diluted earnings per share $ 0.96 $ 2.09 $ 2.62
Weighted average number of shares—basic 36,720,749 36,448,138 36,031,792
Weighted average number of shares—diluted 36,813,719 36,600,803 36,475,102