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Income Taxes - Schedule of Effective Income Tax Rate Reconciliation (Details)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Income Tax Disclosure [Abstract]    
Federal statutory income tax rate 21.00% 21.00%
Federal and state research and development credits 3.70% 3.80%
State taxes, net of federal benefit 4.20% 4.80%
Non-deductible items (0.70%) (1.70%)
Stock-based compensation (1.00%) 1.60%
Change in valuation allowance (27.20%) (29.40%)
Other 0.00% (0.10%)
Effective income tax rate 0.00% 0.00%