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Nature of the Business - Additional Information (Details) $ in Thousands	3 Months Ended				6 Months Ended
	Jun. 30, 2023 USD ($) candidate platform	Mar. 31, 2023 USD ($)	Jun. 30, 2022 USD ($)	Mar. 31, 2022 USD ($)	Jun. 30, 2023 USD ($) candidate platform	Jun. 30, 2022 USD ($)	Dec. 31, 2022 USD ($)
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Number of platforms | platform	2				2
Number of product candidates | candidate	4				4
Proceeds from issuance or sale of equity					$ 613,600
Net loss	$ 34,312	$ 37,455	$ 60,194	$ 68,717	71,767	$ 128,911
Accumulated deficit	602,411				602,411		$ 530,644
Cash and cash equivalents	$ 124,300		$ 56,039		$ 124,300	$ 56,039	$ 61,615

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