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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Cash flows from operating activities:    
Net loss $ (71,767) $ (128,911)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation expense 212 212
Stock-based compensation expense 13,368 15,497
Non-cash operating lease expense 407 366
Amortization of premiums and discounts on marketable securities, net 47 598
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets 4,822 722
Accounts payable (6,662) 1,041
Accrued expenses (2,533) (547)
Operating lease liabilities (490) (352)
Deferred revenue (1,464) 0
Other 0 56
Net cash used in operating activities (64,060) (111,318)
Cash flows from investing activities:    
Purchases of property and equipment 0 (399)
Purchases of marketable securities 0 (83,022)
Maturities of marketable securities 39,000 109,761
Net cash provided by investing activities 39,000 26,340
Cash flows from financing activities:    
Payments of tax withholdings related to vesting of restricted stock units (131) (246)
Proceeds from exercise of stock options and employee stock purchase plan purchases 309 853
Net cash provided by financing activities 87,745 1,713
Increase (decrease) in cash, cash equivalents and restricted cash 62,685 (83,265)
Cash, cash equivalents and restricted cash, beginning of period 62,031 139,720
Cash, cash equivalents and restricted cash, end of period 124,716 56,455
Reconciliation of cash, cash equivalents and restricted cash:    
Cash and cash equivalents 124,300 56,039
Restricted cash 416 416
Total cash, cash equivalents and restricted cash 124,716 56,455
Supplemental disclosures of non-cash activities:    
Offering costs included in accrued expenses 259 0
Follow-On Offering    
Cash flows from financing activities:    
Proceeds from stock offerings, net of issuance costs 63,439 0
At-The-Market Offering    
Cash flows from financing activities:    
Proceeds from stock offerings, net of issuance costs 24,128 1,368
Payment of issuance costs for at-the-market offerings $ 0 $ (262)