<SEC-DOCUMENT>0001104659-23-072451-index.html : 20230620
<SEC-HEADER>0001104659-23-072451.hdr.sgml : 20230620
<ACCEPTANCE-DATETIME>20230620060251
ACCESSION NUMBER:		0001104659-23-072451
CONFORMED SUBMISSION TYPE:	424B5
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20230620
DATE AS OF CHANGE:		20230620

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Praxis Precision Medicines, Inc.
		CENTRAL INDEX KEY:			0001689548
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B5
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-260726
		FILM NUMBER:		231023207

	BUSINESS ADDRESS:	
		STREET 1:		99 HIGH STREET, 30TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02110
		BUSINESS PHONE:		617-300-8460

	MAIL ADDRESS:	
		STREET 1:		99 HIGH STREET, 30TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02110
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B5
<SEQUENCE>1
<FILENAME>tm238261-4_424b5.htm
<DESCRIPTION>424B5
<TEXT>
Document 1 - file: tm238261-4_424b5.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>lg_praxis-4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: lg_praxis-4c.jpg

</DOCUMENT>
</SEC-DOCUMENT>