<SEC-DOCUMENT>0001104659-23-011530-index.html : 20230207
<SEC-HEADER>0001104659-23-011530.hdr.sgml : 20230207
<ACCEPTANCE-DATETIME>20230207090111
ACCESSION NUMBER:		0001104659-23-011530
CONFORMED SUBMISSION TYPE:	POS AM
PUBLIC DOCUMENT COUNT:		4
FILED AS OF DATE:		20230207
DATE AS OF CHANGE:		20230207

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Praxis Precision Medicines, Inc.
		CENTRAL INDEX KEY:			0001689548
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		POS AM
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-260726
		FILM NUMBER:		23592961

	BUSINESS ADDRESS:	
		STREET 1:		99 HIGH STREET, 30TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02110
		BUSINESS PHONE:		617-300-8460

	MAIL ADDRESS:	
		STREET 1:		99 HIGH STREET, 30TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02110
</SEC-HEADER>
<DOCUMENT>
<TYPE>POS AM
<SEQUENCE>1
<FILENAME>tm235118-2_posam.htm
<DESCRIPTION>POS AM
<TEXT>
Document 1 - file: tm235118-2_posam.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-1.2
<SEQUENCE>2
<FILENAME>tm235118d5_ex1-2.htm
<DESCRIPTION>EXHIBIT 1.2
<TEXT>
Document 2 - file: tm235118d5_ex1-2.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>3
<FILENAME>tm235118d5_ex23-2.htm
<DESCRIPTION>EXHIBIT 23.2
<TEXT>
Document 3 - file: tm235118d5_ex23-2.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>lg_praxis-4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: lg_praxis-4c.jpg

</DOCUMENT>
</SEC-DOCUMENT>