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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Cash flows from operating activities:    
Net loss $ (124,140) $ (96,399)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation expense 311 321
Stock-based compensation expense 32,785 19,131
Non-cash operating lease expense 690 619
Amortization of premiums and discounts on marketable securities, net (3,620) 47
Non-cash collaboration and license agreement expense 2,500 0
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets 564 8,109
Accounts payable 9,195 (7,556)
Accrued expenses 8,005 (8,871)
Operating lease liabilities (835) (744)
Deferred revenue (1,090) (1,932)
Net cash used in operating activities (75,635) (87,275)
Cash flows from investing activities:    
Purchases of marketable securities (302,101) 0
Maturities of marketable securities 64,525 39,000
Net cash (used in) provided by investing activities (237,576) 39,000
Cash flows from financing activities:    
Payments of tax withholdings related to vesting of restricted stock units (151) (132)
Proceeds from exercise of stock options and employee stock purchase plan purchases 659 310
Net cash provided by financing activities 400,556 87,745
Increase in cash, cash equivalents and restricted cash 87,345 39,470
Cash, cash equivalents and restricted cash, beginning of period 81,716 62,031
Cash, cash equivalents and restricted cash, end of period 169,061 101,501
Reconciliation of cash, cash equivalents and restricted cash:    
Cash and cash equivalents 168,645 101,085
Restricted cash 416 416
Total cash, cash equivalents and restricted cash 169,061 101,501
Supplemental disclosures of non-cash activities:    
Issuance costs from at-the-market offering included in accrued expenses 36 0
Offering costs from follow-on offering included in accounts payable 0 184
Purchases of property and equipment included in accounts payable 0 50
Follow-On Offering    
Cash flows from financing activities:    
Proceeds from stock offerings, net of issuance costs 377,636 63,439
License And Collaboration Agreement    
Cash flows from financing activities:    
Proceeds from stock offerings, net of issuance costs 14,765 0
At-The-Market Offering    
Cash flows from financing activities:    
Proceeds from stock offerings, net of issuance costs $ 7,647 $ 24,128