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Collaboration and License Agreements - (Details)		1 Months Ended		3 Months Ended
	Jan. 04, 2024 USD ($) obligation $ / shares shares	Dec. 31, 2024 USD ($)	Jan. 31, 2024 USD ($)	Mar. 31, 2026 USD ($) $ / shares	Mar. 31, 2025 USD ($)	Dec. 31, 2022 USD ($) obligation
Disaggregation of Revenue [Line Items]
Number of performance obligations | obligation	1					1
UCB | License
Disaggregation of Revenue [Line Items]
Upfront payment				$ 0		$ 5,000,000.0
Milestone payments						98,500,000
Transaction price						$ 5,000,000.0
Contract with customer, liability, revenue recognized				$ 0	$ 0
UCB | Upfront Payment
Disaggregation of Revenue [Line Items]
Contract with customer, liability, revenue recognized		$ 2,600,000
UCB | Option Exercise Fee
Disaggregation of Revenue [Line Items]
Contract with customer, liability, revenue recognized		$ 6,000,000.0
Tenacia
Disaggregation of Revenue [Line Items]
Number of shares issued in transaction (in shares) | shares	443,253
Sale of stock, price (in dollars per share) | $ / shares	$ 22.5605			$ 38.95
Proceeds from stock offerings, net of issuance costs	$ 10,000,000.0		$ 10,000,000.0
Sale of stock, volume-weighted average price, premium	20.00%			20.00%
Sale of stock, volume-weighted average price, duration	30 days			30 days
Proceeds from collaboration arrangement			14,800,000
Sale of stock, value transferred				$ 17,300,000
Contract with customer, liability, cumulative catch-up adjustment to revenue, modification of contract				$ 2,500,000
Tenacia | License
Disaggregation of Revenue [Line Items]
Upfront payment	$ 5,000,000.0		$ 4,800,000
Milestone payments	$ 264,000,000.0

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