    <SEC-DOCUMENT>0001689548-26-000082-index.html : 20260806
    <SEC-HEADER>0001689548-26-000082.hdr.sgml : 20260806
    <ACCEPTANCE-DATETIME>20260806083127
    ACCESSION NUMBER:		0001689548-26-000082
    CONFORMED SUBMISSION TYPE:	8-K
    PUBLIC DOCUMENT COUNT:		44
    CONFORMED PERIOD OF REPORT:	20260806
    ITEM INFORMATION:		Results of Operations and Financial Condition
    ITEM INFORMATION:		Regulation FD Disclosure
    ITEM INFORMATION:		Financial Statements and Exhibits
    FILED AS OF DATE:		20260806
    DATE AS OF CHANGE:		20260806

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Praxis Precision Medicines, Inc.
    		CENTRAL INDEX KEY:			0001689548
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				000000000
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		8-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-39620
    		FILM NUMBER:		261246240

    	BUSINESS ADDRESS:
    		STREET 1:		99 HIGH STREET, 30TH FLOOR
    		CITY:			BOSTON
    		STATE:			MA
    		ZIP:			02110
    		BUSINESS PHONE:		617-300-8460

    	MAIL ADDRESS:
    		STREET 1:		99 HIGH STREET, 30TH FLOOR
    		CITY:			BOSTON
    		STATE:			MA
    		ZIP:			02110
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>8-K
    <SEQUENCE>1
    <FILENAME>prax-20260806.htm
    <DESCRIPTION>8-K
    <TEXT>
    Document 1 - file: prax-20260806.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.1
    <SEQUENCE>2
    <FILENAME>praxisq22026pr.htm
    <DESCRIPTION>EX-99.1
    <TEXT>
    Document 2 - file: praxisq22026pr.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.2
    <SEQUENCE>3
    <FILENAME>praxiscorporatedeckaugus.htm
    <DESCRIPTION>EX-99.2
    <TEXT>
    Document 3 - file: praxiscorporatedeckaugus.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.SCH
    <SEQUENCE>4
    <FILENAME>prax-20260806.xsd
    <DESCRIPTION>XBRL TAXONOMY EXTENSION SCHEMA DOCUMENT
    <TEXT>
    Document 4 - file: prax-20260806.xsd

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.LAB
    <SEQUENCE>5
    <FILENAME>prax-20260806_lab.xml
    <DESCRIPTION>XBRL TAXONOMY EXTENSION LABEL LINKBASE DOCUMENT
    <TEXT>
    Document 5 - file: prax-20260806_lab.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.PRE
    <SEQUENCE>6
    <FILENAME>prax-20260806_pre.xml
    <DESCRIPTION>XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE DOCUMENT
    <TEXT>
    Document 6 - file: prax-20260806_pre.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>image_0.jpg
    <TEXT>
    Document 7 - file: image_0.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>praxiscorporatedeckaugus001.jpg
    <TEXT>
    Document 8 - file: praxiscorporatedeckaugus001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>praxiscorporatedeckaugus002.jpg
    <TEXT>
    Document 9 - file: praxiscorporatedeckaugus002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>praxiscorporatedeckaugus003.jpg
    <TEXT>
    Document 10 - file: praxiscorporatedeckaugus003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>praxiscorporatedeckaugus004.jpg
    <TEXT>
    Document 11 - file: praxiscorporatedeckaugus004.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>praxiscorporatedeckaugus005.jpg
    <TEXT>
    Document 12 - file: praxiscorporatedeckaugus005.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>praxiscorporatedeckaugus006.jpg
    <TEXT>
    Document 13 - file: praxiscorporatedeckaugus006.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>praxiscorporatedeckaugus007.jpg
    <TEXT>
    Document 14 - file: praxiscorporatedeckaugus007.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>praxiscorporatedeckaugus008.jpg
    <TEXT>
    Document 15 - file: praxiscorporatedeckaugus008.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>praxiscorporatedeckaugus009.jpg
    <TEXT>
    Document 16 - file: praxiscorporatedeckaugus009.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>praxiscorporatedeckaugus010.jpg
    <TEXT>
    Document 17 - file: praxiscorporatedeckaugus010.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>18
    <FILENAME>praxiscorporatedeckaugus011.jpg
    <TEXT>
    Document 18 - file: praxiscorporatedeckaugus011.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>19
    <FILENAME>praxiscorporatedeckaugus012.jpg
    <TEXT>
    Document 19 - file: praxiscorporatedeckaugus012.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>20
    <FILENAME>praxiscorporatedeckaugus013.jpg
    <TEXT>
    Document 20 - file: praxiscorporatedeckaugus013.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>21
    <FILENAME>praxiscorporatedeckaugus014.jpg
    <TEXT>
    Document 21 - file: praxiscorporatedeckaugus014.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>22
    <FILENAME>praxiscorporatedeckaugus015.jpg
    <TEXT>
    Document 22 - file: praxiscorporatedeckaugus015.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>23
    <FILENAME>praxiscorporatedeckaugus016.jpg
    <TEXT>
    Document 23 - file: praxiscorporatedeckaugus016.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>24
    <FILENAME>praxiscorporatedeckaugus017.jpg
    <TEXT>
    Document 24 - file: praxiscorporatedeckaugus017.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>25
    <FILENAME>praxiscorporatedeckaugus018.jpg
    <TEXT>
    Document 25 - file: praxiscorporatedeckaugus018.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>26
    <FILENAME>praxiscorporatedeckaugus019.jpg
    <TEXT>
    Document 26 - file: praxiscorporatedeckaugus019.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>27
    <FILENAME>praxiscorporatedeckaugus020.jpg
    <TEXT>
    Document 27 - file: praxiscorporatedeckaugus020.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>28
    <FILENAME>praxiscorporatedeckaugus021.jpg
    <TEXT>
    Document 28 - file: praxiscorporatedeckaugus021.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>29
    <FILENAME>praxiscorporatedeckaugus022.jpg
    <TEXT>
    Document 29 - file: praxiscorporatedeckaugus022.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>30
    <FILENAME>praxiscorporatedeckaugus023.jpg
    <TEXT>
    Document 30 - file: praxiscorporatedeckaugus023.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>31
    <FILENAME>praxiscorporatedeckaugus024.jpg
    <TEXT>
    Document 31 - file: praxiscorporatedeckaugus024.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>32
    <FILENAME>praxiscorporatedeckaugus025.jpg
    <TEXT>
    Document 32 - file: praxiscorporatedeckaugus025.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>33
    <FILENAME>praxiscorporatedeckaugus026.jpg
    <TEXT>
    Document 33 - file: praxiscorporatedeckaugus026.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>34
    <FILENAME>praxiscorporatedeckaugus027.jpg
    <TEXT>
    Document 34 - file: praxiscorporatedeckaugus027.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>35
    <FILENAME>praxiscorporatedeckaugus028.jpg
    <TEXT>
    Document 35 - file: praxiscorporatedeckaugus028.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>36
    <FILENAME>praxiscorporatedeckaugus029.jpg
    <TEXT>
    Document 36 - file: praxiscorporatedeckaugus029.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>37
    <FILENAME>praxiscorporatedeckaugus030.jpg
    <TEXT>
    Document 37 - file: praxiscorporatedeckaugus030.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>39
    <FILENAME>R1.htm
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 39 - file: R1.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>40
    <FILENAME>report.css
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 40 - file: report.css

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>41
    <FILENAME>Show.js
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 41 - file: Show.js

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>43
    <FILENAME>FilingSummary.xml
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 43 - file: FilingSummary.html

    Document 43 - RAW XML: FilingSummary.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>JSON
    <SEQUENCE>45
    <FILENAME>MetaLinks.json
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 45 - file: MetaLinks.json

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>ZIP
    <SEQUENCE>46
    <FILENAME>0001689548-26-000082-xbrl.zip
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 46 - file: 0001689548-26-000082-xbrl.zip

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>47
    <FILENAME>prax-20260806_htm.xml
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 47 - file: prax-20260806_htm.html

    Document 47 - RAW XML: prax-20260806_htm.xml

    </DOCUMENT>
    </SEC-DOCUMENT>