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Consolidated Statement of Cash Flows - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Cash Flows from Operating Activities:    
Net loss $ (104,199) $ (86,848)
Adjustments to reconcile net loss to net cash used in operating activities:    
Issuance of common stock for in-process research and development expense 0 3,787
Stock-based compensation 16,292 9,268
Depreciation and amortization 199 184
Non-cash lease expense 285 184
Change in fair value of warrant liability (10,187) (4,231)
Net amortization on marketable securities 3,671 4,593
Net loss on marketable securities 1,228 80
Net loss on disposal of property and equipment 50 0
Change in operating assets and liabilities (net of assets and liabilities acquired in the Merger)    
Prepaid expenses and other current assets (177) 2,416
Interest receivable on marketable securities 554 (1,947)
Lease security deposit 283 0
Accounts payable (1,786) 1,861
Accrued expenses (2,321) 7,452
Deferred rent 0 (157)
Net cash used in operating activities (96,108) (68,190)
Cash Flows from Investing Activities:    
Purchases of marketable securities (520,307) (609,300)
Proceeds from marketable securities 584,121 154,913
Purchases of property and equipment (370) (282)
Proceeds from sale of property and equipment 13 0
Net cash provided by (used in) investing activities 63,457 (454,669)
Cash Flows from Financing Activities:    
Proceeds from the Merger, net of offering costs paid 0 624,769
Proceeds from issuance of common stock under ESPP 388 308
Proceeds from exercises of options 939 450
Net cash provided by financing activities 1,327 625,527
Net (decrease) increase in cash and cash equivalents (31,324) 102,668
Cash and cash equivalents, beginning of the period 132,423 29,755
Cash and cash equivalents, end of the period 101,099 132,423
Non-cash operating activity:    
Right-of-use asset recognized 2,171 3,917
Non-cash investing and financing activity:    
Issuance of common stock for in-process research and development $ 0 $ 3,787