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Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Cash flows from operating activities:    
Net loss $ (42,366) $ (56,151)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 10,360 8,364
Depreciation and amortization 112 94
Non-cash lease expense (35) 67
Change in fair value of warrant liability 123 (9,404)
Amortization of premium on marketable securities (5,368) 3,507
Realized loss on marketable securities 195 908
Net loss on disposal of property and equipment 12 0
Change in operating assets and liabilities:    
Prepaid expenses and other current assets 288 (4,156)
Interest receivable on marketable securities (310) 371
Lease security deposit 0 283
Accounts payable 438 8,803
Accrued expenses (264) (4,533)
Net cash used in operating activities (36,815) (51,847)
Cash flow from investing activities:    
Purchases of marketable securities (443,800) (262,672)
Proceeds from sale of marketable securities 429,184 283,957
Purchases of property and equipment (34) (202)
Net cash (used in) provided by investing activities (14,650) (21,083)
Cash flow from financing activities:    
Proceeds from issuance of common stock under ESPP 133 292
Proceeds from exercises of options 298 370
Net cash provided by financing activities 431 662
Net decrease in cash and cash equivalents (51,034) (30,102)
Cash and cash equivalents, beginning of the period 101,099 132,423
Cash and cash equivalents, end of the period 50,065 102,321
Non-cash operating activities    
Right-of-use assets recognized 0 2,171
Operating Lease Liabilities Recognized $ 0 $ 2,171