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Stock-Based Compensation (Tables) | 3 Months Ended
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Mar. 31, 2026
Share-Based Payment Arrangement [Abstract] |
Summary of Stock-Based Compensation Expense | The stock-based compensation expense included in the Company’s consolidated statement of operations and comprehensive loss for the three months ended March 31, 2026 and 2025 is as follows (in thousands):
|  | Three Months Ended March 31, |
|  | 2026 |  |  | 2025 |
Research and development |  | $ | 3,853 |  |  | $ | 3,411 |
General and administrative |  |  | 5,180 |  |  |  | 4,443 |
|  | $ | 9,033 |  |  | $ | 7,854 |
Summary of Stock Option Activity under 2019 Plan and 2021 Plan | The following table summarizes stock option activity under the 2019 Plan, 2021 Plan and assumed options in the AnHeart acquisition for the three months ended March 31, 2026.
|  | Shares |
Outstanding at December 31, 2025 |  |  | 73,963,104 |
Granted |  |  | 12,749,934 |
Exercised |  |  | (1,177,041 | )
Forfeited |  |  | (441,100 | )
Outstanding at March 31, 2026 |  |  | 85,094,897 |
Exercisable at March 31, 2026 |  |  | 40,099,370 |
Summary of Restricted Stock Units Activity | The following table summarizes the activity for the restricted stock units for the three months ended March 31, 2026.
|  | Restricted Stock |
|  | Units |
Non-vested at December 31, 2025 |  |  | 104,027 |
Granted |  |  | 3,420,803 |
Vested |  |  | (12,615 | )
Forfeited or canceled |  |  | (33,840 | )
Non-vested at March 31, 2026 |  |  | 3,478,375 |

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- Definition Tabular disclosure of the number and weighted-average grant date fair value for restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock units that were granted, vested, or forfeited during the year. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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