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Stock-Based Compensation (Tables) | 6 Months Ended
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Jun. 30, 2026
Share-Based Payment Arrangement [Abstract] |
Summary of Stock-Based Compensation Expense | The stock-based compensation expense included in the Company’s consolidated statement of operations and comprehensive loss for the three and six months ended June 30, 2026 and 2025 is as follows (in thousands):
|  | Three months ended June 30, |  |  | Six months ended June 30, |
|  | 2026 |  |  | 2025 |  |  | 2026 |  |  | 2025 |
Research and development |  | $ | 4,473 |  |  | $ | 5,151 |  |  | $ | 8,326 |  |  | $ | 8,562 |
General and administrative |  |  | 5,987 |  |  |  | 6,880 |  |  |  | 11,167 |  |  |  | 11,323 |
|  | $ | 10,460 |  |  | $ | 12,031 |  |  | $ | 19,493 |  |  | $ | 19,885 |
Summary of Stock Option Activity under 2019 Plan and 2021 Plan | The following table summarizes stock option activity under the 2019 Plan, 2021 Plan and assumed options in the AnHeart acquisition for the six months ended June 30, 2026.
|  | Shares |
Outstanding at December 31, 2025 |  |  | 73,963,104 |
Granted |  |  | 13,956,218 |
Exercised |  |  | (2,947,061 | )
Forfeited |  |  | (3,359,048 | )
Outstanding at June 30, 2026 |  |  | 81,613,213 |
Exercisable at June 30, 2026 |  |  | 43,646,295 |
Summary of Restricted Stock Units Activity | The following table summarizes the activity for the restricted stock units for the six months ended June 30, 2026.
|  | Restricted Stock |
|  | Units |
Non-vested at December 31, 2025 |  |  | 104,027 |
Granted |  |  | 3,852,721 |
Vested |  |  | (25,230 | )
Forfeited or canceled |  |  | (225,247 | )
Non-vested at June 30, 2026 |  |  | 3,706,271 |

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