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STATEMENTS OF CASH FLOWS - USD ($)
9 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Operating activities    
Net loss $ (17,730,000) $ (14,448,000)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 130,000 141,000
Lease incentive (25,000) (25,000)
Stock-based compensation expense 1,217,000 16,000
Non cash interest expense 6,000 6,000
Accrual of back end fees related to note payable   (12,000)
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (338,000) (139,000)
Refundable PDUFA fee 2,335,000  
Accounts payable 962,000 1,563,000
Accrued expenses 815,000 2,518,000
Net cash used in operating activities (12,628,000) (10,380,000)
Investing activities    
Purchases of property and equipment (175,000)  
Net cash used in investing activities (175,000)  
Financing activities    
(Repayment of) borrowing from term note (619,000) 7,044,000
Repayment of lease note payable (44,000) (46,000)
Restricted cash (16,000)  
Proceeds from the exercise of stock options 472,000 9,000
Net cash provided by financing activities 116,629,000 7,007,000
Net increase (decrease) in cash and cash equivalents 103,826,000 (3,373,000)
Cash and cash equivalents at beginning of period 1,634,000 7,551,000
Cash and cash equivalents at end of period 105,460,000 4,178,000
Supplemental disclosure of noncash activities    
Accruals of dividends and accretion to redemption value 24,572,000 2,469,000
Conversion of bridge note to preferred stock 5,000,000  
Cash paid for interest 260,000 46,000
Cash paid for taxes 4,000  
Repayment of term note with proceeds of notes payable   $ 944,000
Common stock    
Financing activities    
Proceeds from issuance of stock, net of issuance costs 72,029,000  
Series D convertible redeemable preferred stock    
Financing activities    
Proceeds from issuance of stock, net of issuance costs 44,807,000  
Supplemental disclosure of noncash activities    
Accruals of dividends and accretion to redemption value 24,572,000  
Conversion of redeemable convertible preferred stock into common stock | Redeemable Convertible Preferred Stock    
Supplemental disclosure of noncash activities    
Preferred stock conversion to common stock $ 120,302,000