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Goodwill and Intangible Assets - Amortization Expense (Details) - USD ($)
$ in Thousands
 3 Months Ended 12 Months Ended
Dec. 31, 2022
Sep. 30, 2022
Jun. 30, 2022
Mar. 31, 2022
Dec. 31, 2021
Sep. 30, 2021
Jun. 30, 2021
Mar. 31, 2021
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Finite-Lived Intangible Assets [Line Items]                      
Amortization and impairment expense $ 42,279 $ 37,552 $ 37,501 $ 18,923 $ 16,795 $ 16,796 $ 16,795 $ 16,795 $ 136,255 $ 67,181 $ 60,680
Nucynta Products                      
Finite-Lived Intangible Assets [Line Items]                      
Amortization and impairment expense                 67,181 $ 67,181 $ 60,680
Belbuca                      
Finite-Lived Intangible Assets [Line Items]                      
Amortization and impairment expense                 58,428    
Symproic                      
Finite-Lived Intangible Assets [Line Items]                      
Amortization and impairment expense                 5,646    
Elyxyb                      
Finite-Lived Intangible Assets [Line Items]                      
Amortization and impairment expense                 5,000    
Amortization expense                 214    
Impairment expense                 $ 4,786    
Impairment, Intangible Asset, Finite-Lived, Statement of Income or Comprehensive Income [Extensible Enumeration]                 Cost of Goods and Services Sold