<DOCUMENT>
<TYPE>EX-24.1
<SEQUENCE>2
<FILENAME>exhibit24-1.txt
<DESCRIPTION>POA
<TEXT>
			POWER OF ATTORNEY

       Know all by these presents, that the undersigned hereby constitutes
and appoints each of Colleen Tupper and Shirley R. Kuhlmann, with full power
to act singly, as the undersigned's true and lawful attorney-in-fact with full
power of substitution to:

	(1)	execute for and on behalf of the undersigned, in the
undersigned's capacity as an officer and/or director and/or beneficial owner of
Collegium Pharmaceutical, Inc. (the "Company"), Form ID Application, Forms 3, 4
and 5 in accordance with Section 16(a) of the Securities Exchange Act of 1934,
as amended and the rules thereunder;

	(2)	do and perform any and all acts for and on behalf of the
undersigned which may be necessary or desirable to complete and execute any
such Form ID Application, Forms 3, 4 or 5, complete and execute any amendment
or amendments thereto and timely file such forms with the United States
Securities and Exchange Commission and any stock exchange or similar
authority; and

	(3)	take any other action of any type whatsoever in connection with
the foregoing which, in the opinion of such attorney-in-fact, may be of benefit
to, in the best interest of, or legally required by, the undersigned, it being
understood that the documents executed by such attorney-in-fact on behalf of
the undersigned pursuant to this Power of Attorney shall be in such form and
shall contain such terms and conditions as such attorney-in-fact may approve
in such attorney-in-fact's discretion.

      The undersigned hereby grants to the attorney-in-fact full power and
authority to do and perform any and every act and thing whatsoever requisite,
necessary or proper to be done in the exercise of any of the rights and powers
herein granted, as fully to all intents and purposes as the undersigned might
or could do if personally present, with full power of substitution or
revocation, hereby ratifying and confirming all that such attorney-in-fact,
or such attorney-in-fact's substitute or substitutes, shall lawfully do or
cause to be done by virtue of this power of attorney and the rights and
powers herein granted.

       This power of attorney shall remain in full force and effect until
revoked by the undersigned in a signed writing delivered to the
attorney-in-fact.

       IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney
to be executed as of November 12, 2024.



					/s/ Vikram Karnani
					Signature

					Vikram Karnani
					Print Name

</TEXT>
</DOCUMENT>
