<SEC-DOCUMENT>0001085146-25-004810.txt : 20250811
<SEC-HEADER>0001085146-25-004810.hdr.sgml : 20250811
<ACCEPTANCE-DATETIME>20250811164903
ACCESSION NUMBER:		0001085146-25-004810
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20250811
DATE AS OF CHANGE:		20250811

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			COLLEGIUM PHARMACEUTICAL, INC
		CENTRAL INDEX KEY:			0001267565
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			VA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-88843
		FILM NUMBER:		251202688

	BUSINESS ADDRESS:	
		STREET 1:		100 TECHNOLOGY CENTER DRIVE
		CITY:			STOUGHTON
		STATE:			MA
		ZIP:			02072
		BUSINESS PHONE:		781-713-3699

	MAIL ADDRESS:	
		STREET 1:		100 TECHNOLOGY CENTER DRIVE
		CITY:			STOUGHTON
		STATE:			MA
		ZIP:			02072

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	COLLEGIUM PHARMACEUTICAL INC
		DATE OF NAME CHANGE:	20031020

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PRINCIPAL GLOBAL INVESTORS
		CENTRAL INDEX KEY:			0000769734
		ORGANIZATION NAME:           	
		EIN:				421479618

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		711 HIGH STREET
		CITY:			DES MOINES
		STATE:			IA
		ZIP:			50392-0300
		BUSINESS PHONE:		515-247-5111

	MAIL ADDRESS:	
		STREET 1:		711 HIGH STREET
		CITY:			DES MOINES
		STATE:			IA
		ZIP:			50392-0300

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	INVISTA CAPITAL MANAGEMENT LLC /IA/
		DATE OF NAME CHANGE:	19990512

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	INVISTA CAPITAL MANAGEMENT INC/IA/
		DATE OF NAME CHANGE:	19970211

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	VALUE INVESTORS INC
		DATE OF NAME CHANGE:	19880526
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:ns1="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <previousAccessionNumber>0001085146-24-005627</previousAccessionNumber>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0000769734</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>1</amendmentNo>
      <securitiesClassTitle>Common stock, par value $0.001 per share</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>06/30/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001267565</issuerCik>
        <issuerName>COLLEGIUM PHARMACEUTICAL, INC</issuerName>
        <issuerCusip>19459J104</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <ns1:street1>100 TECHNOLOGY CENTER DRIVE</ns1:street1>
          <ns1:city>STOUGHTON</ns1:city>
          <ns1:stateOrCountry>MA</ns1:stateOrCountry>
          <ns1:zipCode>02072</ns1:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(b)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>PRINCIPAL GLOBAL INVESTORS</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0</soleVotingPower>
        <sharedVotingPower>1466506</sharedVotingPower>
        <soleDispositivePower>0</soleDispositivePower>
        <sharedDispositivePower>1466506</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>1466506</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>4.6</classPercent>
      <typeOfReportingPerson>IA</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>COLLEGIUM PHARMACEUTICAL, INC</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>100 TECHNOLOGY CENTER DRIVE, STOUGHTON, MASSACHUSETTS
02072</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>PRINCIPAL GLOBAL INVESTORS</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>711 HIGH STREET
DES MOINES, Iowa
50392-0300</principalBusinessOfficeOrResidenceAddress>
        <citizenship>PRINCIPAL GLOBAL INVESTORS - DELAWARE</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>N</notApplicableFlag>
        <typeOfPersonFiling>IA</typeOfPersonFiling>
      </item3>
      <item4>
        <amountBeneficiallyOwned>1,466,506</amountBeneficiallyOwned>
        <classPercent>4.6</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>PRINCIPAL GLOBAL INVESTORS - 0</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>PRINCIPAL GLOBAL INVESTORS - 1,466,506</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>PRINCIPAL GLOBAL INVESTORS - 0</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>PRINCIPAL GLOBAL INVESTORS - 1,466,506</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>N</notApplicableFlag>
        <classOwnership5PercentOrLess>Y</classOwnership5PercentOrLess>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>PRINCIPAL GLOBAL INVESTORS</reportingPersonName>
      <signatureDetails>
        <signature>/s/ J. Markham Penrod</signature>
        <title>Chief Compliance Officer - North America, Principal Asset Management</title>
        <date>08/08/2025</date>
      </signatureDetails>
    </signatureInformation>
  </formData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
