XML 67 R40.htm IDEA: XBRL DOCUMENT v3.22.0.1
Commitments and Contingencies - Additional Information (Details)
 1 Months Ended 12 Months Ended
Sep. 30, 2021
USD ($)
ft²
Jun. 30, 2021
USD ($)
ft²
Dec. 31, 2018
USD ($)
ft²
Option
Aug. 31, 2018
USD ($)
ft²
Jul. 31, 2015
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Dec. 31, 2021
GBP (£)
Jan. 01, 2020
USD ($)
Commitments And Contingencies [Line Items]                  
Area of space subject to operating lease | ft²     2,485 23,000          
Operating lease term     3 years 3 years          
Operating lease cost per year     $ 200,000 $ 900,000          
Annual base rent increase percentage for operating lease     2.50% 3.00%          
Operating lease commencement date     May 01, 2019 Dec. 10, 2018          
Operating lease right-of-use assets           $ 4,939,000 $ 1,115,000    
Operating lease liabilities           6,975,000      
Number of options to renewal operating lease term | Option     1            
Operating lease, renewal term     2 years            
Liabilities recorded under agreement           21,088,000 11,847,000    
CSHL Agreement                  
Commitments And Contingencies [Line Items]                  
Percentage of maximum required payment of sublicense revenue         20.00%        
Annual license maintenance fee           10,000.00      
Maximum aggregate potential milestone payments payable           900,000      
Expenses related to reimbursable patent costs           0 0    
Southampton Agreement                  
Commitments And Contingencies [Line Items]                  
Maximum aggregate potential milestone payments payable           500,000   £ 400,000  
Expenses related to reimbursable patent costs           120,000 90,000.00    
Liabilities recorded under agreement           $ 0 0    
Member of Board of Directors                  
Commitments And Contingencies [Line Items]                  
Consulting services expenses             20,000.00    
Consulting services agreement term           5 years      
Scientific advisory services expenses           $ 50,000.00 50,000.00    
Scientific advisory services agreement term           12 months      
ASU 2016-02                  
Commitments And Contingencies [Line Items]                  
Operating lease right-of-use assets                 $ 2,200,000
Operating lease liabilities                 $ 2,200,000
Operating leases expense           $ 1,400,000 $ 1,100,000    
Lease Commencement on December 15, 2021                  
Commitments And Contingencies [Line Items]                  
Area of space subject to operating lease | ft² 23,000                
Operating lease term 3 years                
Operating lease commencement date Dec. 15, 2021                
Operating lease right-of-use assets $ 3,500,000                
Operating lease liabilities $ 3,500,000                
Operating lease expiration date Dec. 31, 2024                
Lease Commencement on April 2022                  
Commitments And Contingencies [Line Items]                  
Area of space subject to operating lease | ft² 15,000                
Operating lease right-of-use assets $ 0                
Operating lease liabilities $ 0                
Operating lease expiration date Dec. 31, 2024                
Operating lease commencement month and year 2022-04                
Lease Extension End Date April 30, 2025                  
Commitments And Contingencies [Line Items]                  
Area of space subject to operating lease | ft²   2,485              
Operating lease term   3 years              
Operating lease commencement date   May 01, 2022              
Operating lease right-of-use assets   $ 700,000              
Operating lease liabilities   $ 700,000              
Operating lease expiration date   Apr. 30, 2025              
Operating lease, renewal term   2 years              
Area of additional space subject to operating lease | ft²   2,357              
Additional operating lease commencement date   Jul. 06, 2021              
Additional operating lease expiration date   Apr. 30, 2025              
Additional operating lease, right-of-use asset   $ 800,000              
Additional operating lease, liabilities   $ 800,000              
Operating lease, option to extend   The amended lease provides the Company with the option to extend the term of the lease for an additional two years.              
Operating lease, existence of option to extend [true false]   true