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Income Taxes (Tables)

12 Months Ended

Dec. 31, 2022

Income Tax Disclosure [Abstract]

Reconciliation of Expected Income Tax Expense (Benefit) using Federal Statutory Income Tax Rate to Effective Income Tax Rate

A reconciliation of the expected income tax expense (benefit) computed using the federal statutory income tax rate the Company’s effective income tax rate is as follows:

		Year ended December 31,
		2022				2021
Expected income tax benefit at the federal statutory rate			21.0		%		21.0		%
State income taxes, net of federal benefit			7.4				7.9
Non-deductible items			(0.9	)			0.4
Research and development credit, net			3.9				4.1
Other			0.1				0.0
Change in valuation allowance			(31.5	)			(33.4	)
Total			0.0		%		0.0		%

Schedule of Deferred Tax Assets and Liabilities

The principal components of the Company’s deferred tax assets and liabilities consist of the following:

		As of December 31,
		2022				2021
Deferred tax assets:
Federal and state net operating loss carryforwards		$	57,746			$	52,231
Research and development tax credits			12,613				7,726
R&D capitalized expenses			17,148				—
Accrued compensation and stock compensation			10,274				6,055
Other			142				20
Gross deferred tax assets			97,923				66,032
Less: valuation allowance			(97,923	)			(66,032	)
Net deferred tax assets		$	—			$	—

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- References

No definition available.

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- Definition

Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 740
-SubTopic 10
-Section 50
-Paragraph 2
-URI https://asc.fasb.org/extlink&oid=121826272&loc=d3e32537-109319

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- Definition

Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 740
-SubTopic 10
-Section 50
-Paragraph 12
-URI https://asc.fasb.org/extlink&oid=121826272&loc=d3e32687-109319

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