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Income Taxes - Reconciliation of Expected Income Tax Expense (Benefit) using Federal Statutory Income Tax Rate to Effective Income Tax Rate (Details)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Income Tax Disclosure [Abstract]    
Expected income tax benefit at the federal statutory rate 21.00% 21.00%
State income taxes, net of federal benefit 7.40% 7.90%
Non-deductible items (0.90%) 0.40%
Research and development credit, net 3.90% 4.10%
Other 0.10% 0.00%
Change in valuation allowance (31.50%) (33.40%)
Total 0.00% 0.00%