XML 39 R30.htm IDEA: XBRL DOCUMENT
v3.25.1

Segment Information (Tables) | 3 Months Ended
--- | ---
Mar. 31, 2025
Segment Reporting [Abstract] |
Summary of Segment Information | The following table reconciles segment direct profit or loss to the Company’s consolidated results (in thousands):
|  | Three Months Ended March 31, |
|  | 2025 |  |  | 2024 |
Revenue |  | $ | 158,569 |  |  | $ | 4,216 |
Zorevunersen(1) |  |  | 17,674 |  |  |  | 8,780 |
ADOA(1) |  |  | 1,201 |  |  |  | 1,722 |
SYNGAP1(1) |  |  | 342 |  |  |  | 284 |
MECP2(1) |  |  | 147 |  |  |  | 242 |
Other external program costs |  |  | 1,829 |  |  |  | 2,043 |
Payroll and other personnel costs - R&D (2) |  |  | 11,012 |  |  |  | 8,163 |
Payroll and other personnel costs - G&A (2) |  |  | 8,929 |  |  |  | 6,850 |
Other non-program costs - R&D (3) |  |  | 1,407 |  |  |  | 1,460 |
Other non-program costs - G&A (3) |  |  | 4,788 |  |  |  | 3,044 |
Subtotal |  |  | (47,329 | ) |  |  | (32,588 | )
Other segment items |  |  |  |  |  |
Interest expense |  |  | (1 | ) |  |  | (22 | )
Interest income |  |  | 2,890 |  |  |  | 2,448 |
Other income (expense) |  |  | 28 |  |  |  | (428 | )
Provision for income taxes |  |  | (1,278 | ) |  |  | — |
Total other segment items |  |  | 1,639 |  |  |  | 1,998 |
Segment net income (loss) |  | $ | 112,879 |  |  | $ | (26,374 | )
(1) Includes external research and development and general and administrative expenses associated with programs. (2) Includes salaries, benefits and other personnel related expenses, including stock based compensation expense, of relevant personnel. (3) Includes costs incurred for conducting non-program activities related to Company activities.

X
- Definition Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 25 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-25 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-22 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
Name: | us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- References No definition available. + Details
Name: | us-gaap_SegmentReportingAbstract
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration