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    <link:loc xlink:href="iart-20151231.xsd#iart_SeniorCreditFacilityMember" xlink:label="loc_iart_SeniorCreditFacilityMember_BBDAFC5948FF24D90BA0197704EEFDF0" xlink:type="locator" />
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    <link:label id="lab_iart_PrincipalAmountToBeConsideredForConversionPurpose_3812228020C61D610AA8197704EF5668_label_en-US" xlink:label="lab_iart_PrincipalAmountToBeConsideredForConversionPurpose_3812228020C61D610AA8197704EF5668" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Principal Amount To Be Considered For Conversion Purpose</link:label>
    <link:label id="lab_iart_PrincipalAmountToBeConsideredForConversionPurpose_3812228020C61D610AA8197704EF5668_documentation_en-US" xlink:label="lab_iart_PrincipalAmountToBeConsideredForConversionPurpose_3812228020C61D610AA8197704EF5668" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Principal amount of notes for each initial conversion into common shares.</link:label>
    <link:loc xlink:href="iart-20151231.xsd#iart_PrincipalAmountToBeConsideredForConversionPurpose" xlink:label="loc_iart_PrincipalAmountToBeConsideredForConversionPurpose_3812228020C61D610AA8197704EF5668" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_iart_PrincipalAmountToBeConsideredForConversionPurpose_3812228020C61D610AA8197704EF5668" xlink:to="lab_iart_PrincipalAmountToBeConsideredForConversionPurpose_3812228020C61D610AA8197704EF5668" xlink:type="arc" />
    <link:label id="lab_us-gaap_DebtInstrumentConvertibleConversionPrice1_F04BCCAFF6999E18856A197704EF8052_terseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentConvertibleConversionPrice1_F04BCCAFF6999E18856A197704EF8052" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Initial conversion price, per share</link:label>
    <link:label id="lab_us-gaap_DebtInstrumentConvertibleConversionPrice1_F04BCCAFF6999E18856A197704EF8052_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentConvertibleConversionPrice1_F04BCCAFF6999E18856A197704EF8052" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Debt Instrument, Convertible, Conversion Price</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentConvertibleConversionPrice1" xlink:label="loc_us-gaap_DebtInstrumentConvertibleConversionPrice1_F04BCCAFF6999E18856A197704EF8052" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentConvertibleConversionPrice1_F04BCCAFF6999E18856A197704EF8052" xlink:to="lab_us-gaap_DebtInstrumentConvertibleConversionPrice1_F04BCCAFF6999E18856A197704EF8052" xlink:type="arc" />
    <link:label id="lab_iart_MaximumSellingPriceOfCompanysCommonStock_1D3589E67F5939ED0B53197704EF8FA6_terseLabel_en-US" xlink:label="lab_iart_MaximumSellingPriceOfCompanysCommonStock_1D3589E67F5939ED0B53197704EF8FA6" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Maximum selling price of company's common stock</link:label>
    <link:label id="lab_iart_MaximumSellingPriceOfCompanysCommonStock_1D3589E67F5939ED0B53197704EF8FA6_label_en-US" xlink:label="lab_iart_MaximumSellingPriceOfCompanysCommonStock_1D3589E67F5939ED0B53197704EF8FA6" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Maximum Selling Price Of Companys Common Stock</link:label>
    <link:label id="lab_iart_MaximumSellingPriceOfCompanysCommonStock_1D3589E67F5939ED0B53197704EF8FA6_documentation_en-US" xlink:label="lab_iart_MaximumSellingPriceOfCompanysCommonStock_1D3589E67F5939ED0B53197704EF8FA6" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">The notes are convertible if the closing price of the Company's stock price exceeds this percentage of the conversion price during a period as defined in the indenture.</link:label>
    <link:loc xlink:href="iart-20151231.xsd#iart_MaximumSellingPriceOfCompanysCommonStock" xlink:label="loc_iart_MaximumSellingPriceOfCompanysCommonStock_1D3589E67F5939ED0B53197704EF8FA6" xlink:type="locator" />
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    <link:label id="lab_iart_PrincipalAmountOfNotesPerAverageTradingPrice_B4C6103680CAAF419538197704EF9F57_terseLabel_en-US" xlink:label="lab_iart_PrincipalAmountOfNotesPerAverageTradingPrice_B4C6103680CAAF419538197704EF9F57" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Principal amount of notes per average trading price</link:label>
    <link:label id="lab_iart_PrincipalAmountOfNotesPerAverageTradingPrice_B4C6103680CAAF419538197704EF9F57_label_en-US" xlink:label="lab_iart_PrincipalAmountOfNotesPerAverageTradingPrice_B4C6103680CAAF419538197704EF9F57" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Principal Amount Of Notes Per Average Trading Price</link:label>
    <link:label id="lab_iart_PrincipalAmountOfNotesPerAverageTradingPrice_B4C6103680CAAF419538197704EF9F57_documentation_en-US" xlink:label="lab_iart_PrincipalAmountOfNotesPerAverageTradingPrice_B4C6103680CAAF419538197704EF9F57" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Principal amount of notes for determining if the average trading price is in excess of this percentage of the conversion value.</link:label>
    <link:loc xlink:href="iart-20151231.xsd#iart_PrincipalAmountOfNotesPerAverageTradingPrice" xlink:label="loc_iart_PrincipalAmountOfNotesPerAverageTradingPrice_B4C6103680CAAF419538197704EF9F57" xlink:type="locator" />
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    <link:label id="lab_iart_MaximumAverageConversionValueOfNotes_4553B9D274AE8ADCDA61197704EFD809_terseLabel_en-US" xlink:label="lab_iart_MaximumAverageConversionValueOfNotes_4553B9D274AE8ADCDA61197704EFD809" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Maximum average conversion value of the notes</link:label>
    <link:label id="lab_iart_MaximumAverageConversionValueOfNotes_4553B9D274AE8ADCDA61197704EFD809_label_en-US" xlink:label="lab_iart_MaximumAverageConversionValueOfNotes_4553B9D274AE8ADCDA61197704EFD809" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Maximum Average Conversion Value Of Notes</link:label>
    <link:label id="lab_iart_MaximumAverageConversionValueOfNotes_4553B9D274AE8ADCDA61197704EFD809_documentation_en-US" xlink:label="lab_iart_MaximumAverageConversionValueOfNotes_4553B9D274AE8ADCDA61197704EFD809" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">The notes are convertible if the average trading price per $1000 principal amount of notes is less than or equal to this percentage of the average conversion value of the notes during a period as defined in the indenture.</link:label>
    <link:loc xlink:href="iart-20151231.xsd#iart_MaximumAverageConversionValueOfNotes" xlink:label="loc_iart_MaximumAverageConversionValueOfNotes_4553B9D274AE8ADCDA61197704EFD809" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_iart_MaximumAverageConversionValueOfNotes_4553B9D274AE8ADCDA61197704EFD809" xlink:to="lab_iart_MaximumAverageConversionValueOfNotes_4553B9D274AE8ADCDA61197704EFD809" xlink:type="arc" />
    <link:label id="lab_iart_EarliestConversionDate_C33372ACB919802F2A00197704F06D12_terseLabel_en-US" xlink:label="lab_iart_EarliestConversionDate_C33372ACB919802F2A00197704F06D12" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Earliest conversion date</link:label>
    <link:label id="lab_iart_EarliestConversionDate_C33372ACB919802F2A00197704F06D12_label_en-US" xlink:label="lab_iart_EarliestConversionDate_C33372ACB919802F2A00197704F06D12" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Earliest Conversion Date</link:label>
    <link:label id="lab_iart_EarliestConversionDate_C33372ACB919802F2A00197704F06D12_documentation_en-US" xlink:label="lab_iart_EarliestConversionDate_C33372ACB919802F2A00197704F06D12" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">The earliest conversion date if none of the other conversion criteria are met</link:label>
    <link:loc xlink:href="iart-20151231.xsd#iart_EarliestConversionDate" xlink:label="loc_iart_EarliestConversionDate_C33372ACB919802F2A00197704F06D12" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_iart_EarliestConversionDate_C33372ACB919802F2A00197704F06D12" xlink:to="lab_iart_EarliestConversionDate_C33372ACB919802F2A00197704F06D12" xlink:type="arc" />
    <link:label id="lab_iart_DebtInstrumentConvertibleNumberofDebtInstrumentsPendingConversion_871DD44140F45143BD01197704F0AFB3_terseLabel_en-US" xlink:label="lab_iart_DebtInstrumentConvertibleNumberofDebtInstrumentsPendingConversion_871DD44140F45143BD01197704F0AFB3" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Debt instrument, convertible, number of debt instruments pending conversion</link:label>
    <link:label id="lab_iart_DebtInstrumentConvertibleNumberofDebtInstrumentsPendingConversion_871DD44140F45143BD01197704F0AFB3_label_en-US" xlink:label="lab_iart_DebtInstrumentConvertibleNumberofDebtInstrumentsPendingConversion_871DD44140F45143BD01197704F0AFB3" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Debt Instrument, Convertible, Number of Debt Instruments Pending Conversion</link:label>
    <link:label id="lab_iart_DebtInstrumentConvertibleNumberofDebtInstrumentsPendingConversion_871DD44140F45143BD01197704F0AFB3_documentation_en-US" xlink:label="lab_iart_DebtInstrumentConvertibleNumberofDebtInstrumentsPendingConversion_871DD44140F45143BD01197704F0AFB3" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Debt Instrument, Convertible, Number of Debt Instruments Pending Conversion</link:label>
    <link:loc xlink:href="iart-20151231.xsd#iart_DebtInstrumentConvertibleNumberofDebtInstrumentsPendingConversion" xlink:label="loc_iart_DebtInstrumentConvertibleNumberofDebtInstrumentsPendingConversion_871DD44140F45143BD01197704F0AFB3" xlink:type="locator" />
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    <link:label id="lab_us-gaap_RepaymentsOfDebt_748379ACA20965419993197704F0E86C_terseLabel_en-US" xlink:label="lab_us-gaap_RepaymentsOfDebt_748379ACA20965419993197704F0E86C" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Repayments of debt</link:label>
    <link:label id="lab_us-gaap_RepaymentsOfDebt_748379ACA20965419993197704F0E86C_label_en-US" xlink:label="lab_us-gaap_RepaymentsOfDebt_748379ACA20965419993197704F0E86C" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Repayments of Debt</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RepaymentsOfDebt" xlink:label="loc_us-gaap_RepaymentsOfDebt_748379ACA20965419993197704F0E86C" xlink:type="locator" />
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    <link:label id="lab_us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities_62BD22D9449205A77F6D197704F08A73_terseLabel_en-US" xlink:label="lab_us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities_62BD22D9449205A77F6D197704F08A73" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Stock issued during period, shares, conversion of convertible securities</link:label>
    <link:label id="lab_us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities_62BD22D9449205A77F6D197704F08A73_label_en-US" xlink:label="lab_us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities_62BD22D9449205A77F6D197704F08A73" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Stock Issued During Period, Shares, Conversion of Convertible Securities</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities_62BD22D9449205A77F6D197704F08A73" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities_62BD22D9449205A77F6D197704F08A73" xlink:to="lab_us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities_62BD22D9449205A77F6D197704F08A73" xlink:type="arc" />
    <link:label id="lab_iart_DerivativePriceOfCallTransactionStrikePrice_5ECD84CC8E05C936CC5C197704F5F516_terseLabel_en-US" xlink:label="lab_iart_DerivativePriceOfCallTransactionStrikePrice_5ECD84CC8E05C936CC5C197704F5F516" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Strike price of the call transaction (in dollars per share)</link:label>
    <link:label id="lab_iart_DerivativePriceOfCallTransactionStrikePrice_5ECD84CC8E05C936CC5C197704F5F516_label_en-US" xlink:label="lab_iart_DerivativePriceOfCallTransactionStrikePrice_5ECD84CC8E05C936CC5C197704F5F516" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Derivative Price Of Call Transaction Strike Price</link:label>
    <link:label id="lab_iart_DerivativePriceOfCallTransactionStrikePrice_5ECD84CC8E05C936CC5C197704F5F516_documentation_en-US" xlink:label="lab_iart_DerivativePriceOfCallTransactionStrikePrice_5ECD84CC8E05C936CC5C197704F5F516" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Derivative price of the call transaction, strike price.</link:label>
    <link:loc xlink:href="iart-20151231.xsd#iart_DerivativePriceOfCallTransactionStrikePrice" xlink:label="loc_iart_DerivativePriceOfCallTransactionStrikePrice_5ECD84CC8E05C936CC5C197704F5F516" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_iart_DerivativePriceOfCallTransactionStrikePrice_5ECD84CC8E05C936CC5C197704F5F516" xlink:to="lab_iart_DerivativePriceOfCallTransactionStrikePrice_5ECD84CC8E05C936CC5C197704F5F516" xlink:type="arc" />
    <link:label id="lab_iart_StrikePriceOfWarrantTransactions_22F23BED540BD0D9FB26197704F5D87B_terseLabel_en-US" xlink:label="lab_iart_StrikePriceOfWarrantTransactions_22F23BED540BD0D9FB26197704F5D87B" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Strike price of warrant transactions (in dollars per share)</link:label>
    <link:label id="lab_iart_StrikePriceOfWarrantTransactions_22F23BED540BD0D9FB26197704F5D87B_label_en-US" xlink:label="lab_iart_StrikePriceOfWarrantTransactions_22F23BED540BD0D9FB26197704F5D87B" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Strike Price Of Warrant Transactions</link:label>
    <link:label id="lab_iart_StrikePriceOfWarrantTransactions_22F23BED540BD0D9FB26197704F5D87B_documentation_en-US" xlink:label="lab_iart_StrikePriceOfWarrantTransactions_22F23BED540BD0D9FB26197704F5D87B" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Strike price of the warrant transactions entered into with affiliates of the initial purchasers of the Notes.</link:label>
    <link:loc xlink:href="iart-20151231.xsd#iart_StrikePriceOfWarrantTransactions" xlink:label="loc_iart_StrikePriceOfWarrantTransactions_22F23BED540BD0D9FB26197704F5D87B" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_iart_StrikePriceOfWarrantTransactions_22F23BED540BD0D9FB26197704F5D87B" xlink:to="lab_iart_StrikePriceOfWarrantTransactions_22F23BED540BD0D9FB26197704F5D87B" xlink:type="arc" />
    <link:label id="lab_iart_AmortizationOfDebtDiscountPremiumInterestCostsCapitalized_CE488285451A01C3A7C6197704F55442_verboseLabel_en-US" xlink:label="lab_iart_AmortizationOfDebtDiscountPremiumInterestCostsCapitalized_CE488285451A01C3A7C6197704F55442" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Amortization of debt discount (premium), interest costs capitalized</link:label>
    <link:label id="lab_iart_AmortizationOfDebtDiscountPremiumInterestCostsCapitalized_CE488285451A01C3A7C6197704F55442_label_en-US" xlink:label="lab_iart_AmortizationOfDebtDiscountPremiumInterestCostsCapitalized_CE488285451A01C3A7C6197704F55442" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Amortization of Debt Discount (Premium), Interest Costs Capitalized</link:label>
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    <link:loc xlink:href="iart-20151231.xsd#iart_AmortizationOfDebtDiscountPremiumInterestCostsCapitalized" xlink:label="loc_iart_AmortizationOfDebtDiscountPremiumInterestCostsCapitalized_CE488285451A01C3A7C6197704F55442" xlink:type="locator" />
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    <link:label id="lab_iart_InterestExpenseDebtExcludingAmortizationInterestCostsCapitalized_EBCDF9C4770A892663E5197704F5D10A_verboseLabel_en-US" xlink:label="lab_iart_InterestExpenseDebtExcludingAmortizationInterestCostsCapitalized_EBCDF9C4770A892663E5197704F5D10A" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Interest expense, debt, excluding amortization, interest costs capitalized</link:label>
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    <link:label id="lab_us-gaap_IncreaseDecreaseInInventories_2452F3049BD09C65454E19292CB067ED_negatedLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInInventories_2452F3049BD09C65454E19292CB067ED" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xml:lang="en-US">Inventories</link:label>
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    <link:label id="lab_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_6091D62877677D08C79C19292CB1216C_negatedLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_6091D62877677D08C79C19292CB1216C" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xml:lang="en-US">Prepaid expenses and other current assets</link:label>
    <link:label id="lab_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_6091D62877677D08C79C19292CB1216C_label_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_6091D62877677D08C79C19292CB1216C" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Increase (Decrease) in Prepaid Expense and Other Assets</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_6091D62877677D08C79C19292CB1216C" xlink:type="locator" />
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    <link:label id="lab_us-gaap_IncreaseDecreaseInOtherOperatingAssets_DB01EF51A2F2EC0E00AA19292CB17741_negatedLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInOtherOperatingAssets_DB01EF51A2F2EC0E00AA19292CB17741" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xml:lang="en-US">Other non-current assets</link:label>
    <link:label id="lab_us-gaap_IncreaseDecreaseInOtherOperatingAssets_DB01EF51A2F2EC0E00AA19292CB17741_label_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInOtherOperatingAssets_DB01EF51A2F2EC0E00AA19292CB17741" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Increase (Decrease) in Other Operating Assets</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncreaseDecreaseInOtherOperatingAssets" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_DB01EF51A2F2EC0E00AA19292CB17741" xlink:type="locator" />
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    <link:label id="lab_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_B8CF33A090D58C30731919292CB1B58C_terseLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_B8CF33A090D58C30731919292CB1B58C" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Accounts payable, accrued expenses and other current liabilities</link:label>
    <link:label id="lab_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_B8CF33A090D58C30731919292CB1B58C_label_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_B8CF33A090D58C30731919292CB1B58C" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Increase (Decrease) in Accounts Payable and Accrued Liabilities</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_B8CF33A090D58C30731919292CB1B58C" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_B8CF33A090D58C30731919292CB1B58C" xlink:to="lab_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_B8CF33A090D58C30731919292CB1B58C" xlink:type="arc" />
    <link:label id="lab_us-gaap_IncreaseDecreaseInDeferredRevenue_167D5C0AA2A7FE50D97219292CB12098_terseLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInDeferredRevenue_167D5C0AA2A7FE50D97219292CB12098" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Deferred revenue</link:label>
    <link:label id="lab_us-gaap_IncreaseDecreaseInDeferredRevenue_167D5C0AA2A7FE50D97219292CB12098_label_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInDeferredRevenue_167D5C0AA2A7FE50D97219292CB12098" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Increase (Decrease) in Deferred Revenue</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncreaseDecreaseInDeferredRevenue" xlink:label="loc_us-gaap_IncreaseDecreaseInDeferredRevenue_167D5C0AA2A7FE50D97219292CB12098" xlink:type="locator" />
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    <link:label id="lab_us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities_9DCD2826EC195CA32B6619292CB19840_terseLabel_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities_9DCD2826EC195CA32B6619292CB19840" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Other non-current liabilities</link:label>
    <link:label id="lab_us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities_9DCD2826EC195CA32B6619292CB19840_label_en-US" xlink:label="lab_us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities_9DCD2826EC195CA32B6619292CB19840" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Increase (Decrease) in Other Noncurrent Liabilities</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities_9DCD2826EC195CA32B6619292CB19840" xlink:type="locator" />
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    <link:label id="lab_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations_3ACC04D62C9D0860857319292CB171F2_totalLabel_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations_3ACC04D62C9D0860857319292CB171F2" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Net cash provided by operating activities of continuing operations</link:label>
    <link:label id="lab_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations_3ACC04D62C9D0860857319292CB171F2_label_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations_3ACC04D62C9D0860857319292CB171F2" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Net Cash Provided by (Used in) Operating Activities, Continuing Operations</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations_3ACC04D62C9D0860857319292CB171F2" xlink:type="locator" />
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    <link:label id="lab_us-gaap_Depreciation_9166B4ECD2BCA56DB9D8197706865203_terseLabel_en-US" xlink:label="lab_us-gaap_Depreciation_9166B4ECD2BCA56DB9D8197706865203" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Depreciation expense</link:label>
    <link:label id="lab_us-gaap_Depreciation_9166B4ECD2BCA56DB9D8197706865203_label_en-US" xlink:label="lab_us-gaap_Depreciation_9166B4ECD2BCA56DB9D8197706865203" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Depreciation</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_Depreciation" xlink:label="loc_us-gaap_Depreciation_9166B4ECD2BCA56DB9D8197706865203" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_Depreciation_9166B4ECD2BCA56DB9D8197706865203" xlink:to="lab_us-gaap_Depreciation_9166B4ECD2BCA56DB9D8197706865203" xlink:type="arc" />
    <link:label id="lab_us-gaap_CapitalLeasedAssetsGross_F7020A3DA6CC7FC6C65A197706864C4F_terseLabel_en-US" xlink:label="lab_us-gaap_CapitalLeasedAssetsGross_F7020A3DA6CC7FC6C65A197706864C4F" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Capital leased assets, gross</link:label>
    <link:label id="lab_us-gaap_CapitalLeasedAssetsGross_F7020A3DA6CC7FC6C65A197706864C4F_label_en-US" xlink:label="lab_us-gaap_CapitalLeasedAssetsGross_F7020A3DA6CC7FC6C65A197706864C4F" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Capital Leased Assets, Gross</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CapitalLeasedAssetsGross" xlink:label="loc_us-gaap_CapitalLeasedAssetsGross_F7020A3DA6CC7FC6C65A197706864C4F" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CapitalLeasedAssetsGross_F7020A3DA6CC7FC6C65A197706864C4F" xlink:to="lab_us-gaap_CapitalLeasedAssetsGross_F7020A3DA6CC7FC6C65A197706864C4F" xlink:type="arc" />
    <link:label id="lab_us-gaap_CapitalLeasesLesseeBalanceSheetAssetsByMajorClassAccumulatedDeprecation_DAF14FAFB8BBCC48AA9B197706869C7B_terseLabel_en-US" xlink:label="lab_us-gaap_CapitalLeasesLesseeBalanceSheetAssetsByMajorClassAccumulatedDeprecation_DAF14FAFB8BBCC48AA9B197706869C7B" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Capital leases, lessee balance sheet, assets by major class, accumulated depreciation</link:label>
    <link:label id="lab_us-gaap_CapitalLeasesLesseeBalanceSheetAssetsByMajorClassAccumulatedDeprecation_DAF14FAFB8BBCC48AA9B197706869C7B_label_en-US" xlink:label="lab_us-gaap_CapitalLeasesLesseeBalanceSheetAssetsByMajorClassAccumulatedDeprecation_DAF14FAFB8BBCC48AA9B197706869C7B" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Capital Leases, Lessee Balance Sheet, Assets by Major Class, Accumulated Depreciation</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CapitalLeasesLesseeBalanceSheetAssetsByMajorClassAccumulatedDeprecation" xlink:label="loc_us-gaap_CapitalLeasesLesseeBalanceSheetAssetsByMajorClassAccumulatedDeprecation_DAF14FAFB8BBCC48AA9B197706869C7B" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CapitalLeasesLesseeBalanceSheetAssetsByMajorClassAccumulatedDeprecation_DAF14FAFB8BBCC48AA9B197706869C7B" xlink:to="lab_us-gaap_CapitalLeasesLesseeBalanceSheetAssetsByMajorClassAccumulatedDeprecation_DAF14FAFB8BBCC48AA9B197706869C7B" xlink:type="arc" />
    <link:label id="lab_us-gaap_InterestCostsCapitalizedAdjustment_A1EA8E8CED9835DD3943197706862AD7_terseLabel_en-US" xlink:label="lab_us-gaap_InterestCostsCapitalizedAdjustment_A1EA8E8CED9835DD3943197706862AD7" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Interest expense capitalized to property, plant, and equipment</link:label>
    <link:label id="lab_us-gaap_InterestCostsCapitalizedAdjustment_A1EA8E8CED9835DD3943197706862AD7_label_en-US" xlink:label="lab_us-gaap_InterestCostsCapitalizedAdjustment_A1EA8E8CED9835DD3943197706862AD7" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Interest Costs Capitalized Adjustment</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InterestCostsCapitalizedAdjustment" xlink:label="loc_us-gaap_InterestCostsCapitalizedAdjustment_A1EA8E8CED9835DD3943197706862AD7" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InterestCostsCapitalizedAdjustment_A1EA8E8CED9835DD3943197706862AD7" xlink:to="lab_us-gaap_InterestCostsCapitalizedAdjustment_A1EA8E8CED9835DD3943197706862AD7" xlink:type="arc" />
    <link:label id="lab_iart_NumberofReportableSegments.GoodwillReallocated_5DA3F6B98260C7692F5519B5C4ADD361_terseLabel_en-US" xlink:label="lab_iart_NumberofReportableSegments.GoodwillReallocated_5DA3F6B98260C7692F5519B5C4ADD361" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Number of reportable segments, goodwill reallocated</link:label>
    <link:label id="lab_iart_NumberofReportableSegments.GoodwillReallocated_5DA3F6B98260C7692F5519B5C4ADD361_label_en-US" xlink:label="lab_iart_NumberofReportableSegments.GoodwillReallocated_5DA3F6B98260C7692F5519B5C4ADD361" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Number of Reportable Segments. Goodwill Reallocated</link:label>
    <link:label id="lab_iart_NumberofReportableSegments.GoodwillReallocated_5DA3F6B98260C7692F5519B5C4ADD361_documentation_en-US" xlink:label="lab_iart_NumberofReportableSegments.GoodwillReallocated_5DA3F6B98260C7692F5519B5C4ADD361" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Number of Reportable Segments. Goodwill Reallocated</link:label>
    <link:loc xlink:href="iart-20151231.xsd#iart_NumberofReportableSegments.GoodwillReallocated" xlink:label="loc_iart_NumberofReportableSegments.GoodwillReallocated_5DA3F6B98260C7692F5519B5C4ADD361" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_iart_NumberofReportableSegments.GoodwillReallocated_5DA3F6B98260C7692F5519B5C4ADD361" xlink:to="lab_iart_NumberofReportableSegments.GoodwillReallocated_5DA3F6B98260C7692F5519B5C4ADD361" xlink:type="arc" />
    <link:label id="lab_us-gaap_GoodwillImpairmentLoss_CA5E7DCCE1BAE21FDADC19770687F102_terseLabel_en-US" xlink:label="lab_us-gaap_GoodwillImpairmentLoss_CA5E7DCCE1BAE21FDADC19770687F102" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Goodwill, impairment loss</link:label>
    <link:label id="lab_us-gaap_GoodwillImpairmentLoss_CA5E7DCCE1BAE21FDADC19770687F102_label_en-US" xlink:label="lab_us-gaap_GoodwillImpairmentLoss_CA5E7DCCE1BAE21FDADC19770687F102" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Goodwill, Impairment Loss</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_GoodwillImpairmentLoss" xlink:label="loc_us-gaap_GoodwillImpairmentLoss_CA5E7DCCE1BAE21FDADC19770687F102" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_GoodwillImpairmentLoss_CA5E7DCCE1BAE21FDADC19770687F102" xlink:to="lab_us-gaap_GoodwillImpairmentLoss_CA5E7DCCE1BAE21FDADC19770687F102" xlink:type="arc" />
    <link:label id="lab_us-gaap_OtherIndefiniteLivedIntangibleAssets_AD76D6C2A51ECE6BE949197706871C30_verboseLabel_en-US" xlink:label="lab_us-gaap_OtherIndefiniteLivedIntangibleAssets_AD76D6C2A51ECE6BE949197706871C30" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Other Indefinite-lived intangible assets</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherIndefiniteLivedIntangibleAssets" xlink:label="loc_us-gaap_OtherIndefiniteLivedIntangibleAssets_AD76D6C2A51ECE6BE949197706871C30" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OtherIndefiniteLivedIntangibleAssets_AD76D6C2A51ECE6BE949197706871C30" xlink:to="lab_us-gaap_OtherIndefiniteLivedIntangibleAssets_AD76D6C2A51ECE6BE949197706871C30" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetUsefulLife_0EF149C0BD68DFB7E3BF1977068774B3_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetUsefulLife_0EF149C0BD68DFB7E3BF1977068774B3" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Finite-lived intangible asset, useful life</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_0EF149C0BD68DFB7E3BF1977068774B3" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_0EF149C0BD68DFB7E3BF1977068774B3" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetUsefulLife_0EF149C0BD68DFB7E3BF1977068774B3" xlink:type="arc" />
    <link:label id="lab_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_67A6A658F1C06D36A10F197706879B75_terseLabel_en-US" xlink:label="lab_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_67A6A658F1C06D36A10F197706879B75" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Impairment of indefinite-lived Assets</link:label>
    <link:label id="lab_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_67A6A658F1C06D36A10F197706879B75_label_en-US" xlink:label="lab_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_67A6A658F1C06D36A10F197706879B75" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Impairment of Intangible Assets, Indefinite-lived (Excluding Goodwill)</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_67A6A658F1C06D36A10F197706879B75" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_67A6A658F1C06D36A10F197706879B75" xlink:to="lab_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_67A6A658F1C06D36A10F197706879B75" xlink:type="arc" />
    <link:label id="lab_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_EB511AB7D6A0560E048719770687EE6F_terseLabel_en-US" xlink:label="lab_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_EB511AB7D6A0560E048719770687EE6F" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Impairment charges</link:label>
    <link:label id="lab_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_EB511AB7D6A0560E048719770687EE6F_label_en-US" xlink:label="lab_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_EB511AB7D6A0560E048719770687EE6F" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Impairment of Intangible Assets (Excluding Goodwill)</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_EB511AB7D6A0560E048719770687EE6F" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_EB511AB7D6A0560E048719770687EE6F" xlink:to="lab_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_EB511AB7D6A0560E048719770687EE6F" xlink:type="arc" />
    <link:label id="lab_us-gaap_AdjustmentForAmortization_7D00C7CD0B662453D8D719770687BE8A_terseLabel_en-US" xlink:label="lab_us-gaap_AdjustmentForAmortization_7D00C7CD0B662453D8D719770687BE8A" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Amortization expense</link:label>
    <link:label id="lab_us-gaap_AdjustmentForAmortization_7D00C7CD0B662453D8D719770687BE8A_label_en-US" xlink:label="lab_us-gaap_AdjustmentForAmortization_7D00C7CD0B662453D8D719770687BE8A" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Amortization</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AdjustmentForAmortization" xlink:label="loc_us-gaap_AdjustmentForAmortization_7D00C7CD0B662453D8D719770687BE8A" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AdjustmentForAmortization_7D00C7CD0B662453D8D719770687BE8A" xlink:to="lab_us-gaap_AdjustmentForAmortization_7D00C7CD0B662453D8D719770687BE8A" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_BABF9F861C9B602BECF019770687B5BC_verboseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_BABF9F861C9B602BECF019770687B5BC" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Annual amortization expense expected to approximate in 2015</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_BABF9F861C9B602BECF019770687B5BC_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_BABF9F861C9B602BECF019770687B5BC" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Next Twelve Months</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_BABF9F861C9B602BECF019770687B5BC" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_BABF9F861C9B602BECF019770687B5BC" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_BABF9F861C9B602BECF019770687B5BC" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_FFB4F877BE6628CE32CF1977068710E2_verboseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_FFB4F877BE6628CE32CF1977068710E2" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Annual amortization expense expected to approximate in 2016</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_FFB4F877BE6628CE32CF1977068710E2_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_FFB4F877BE6628CE32CF1977068710E2" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Year Two</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_FFB4F877BE6628CE32CF1977068710E2" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_FFB4F877BE6628CE32CF1977068710E2" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_FFB4F877BE6628CE32CF1977068710E2" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_FE8642FBC70518086104197706879374_verboseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_FE8642FBC70518086104197706879374" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Annual amortization expense expected to approximate in 2017</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_FE8642FBC70518086104197706879374_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_FE8642FBC70518086104197706879374" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Year Three</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_FE8642FBC70518086104197706879374" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_FE8642FBC70518086104197706879374" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_FE8642FBC70518086104197706879374" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_298F706252B996DC1AB5197706871E94_verboseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_298F706252B996DC1AB5197706871E94" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Annual amortization expense expected to approximate in 2018</link:label>
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    <link:loc xlink:href="iart-20151231.xsd#iart_ExtendedWarrantiesInYears" xlink:label="loc_iart_ExtendedWarrantiesInYears_84DBF352F175C163FF2719770687306A" xlink:type="locator" />
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    <link:label id="lab_us-gaap_ProductWarrantyAccrual_FD9C747B707514527158197706873FD8_terseLabel_en-US" xlink:label="lab_us-gaap_ProductWarrantyAccrual_FD9C747B707514527158197706873FD8" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Accrued warranty expense</link:label>
    <link:label id="lab_us-gaap_ProductWarrantyAccrual_FD9C747B707514527158197706873FD8_label_en-US" xlink:label="lab_us-gaap_ProductWarrantyAccrual_FD9C747B707514527158197706873FD8" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Product Warranty Accrual</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ProductWarrantyAccrual" xlink:label="loc_us-gaap_ProductWarrantyAccrual_FD9C747B707514527158197706873FD8" xlink:type="locator" />
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    <link:label id="lab_us-gaap_DefinedBenefitPlanContributionsByEmployer_D92FF95F1F68A13D97411977068775D5_verboseLabel_en-US" xlink:label="lab_us-gaap_DefinedBenefitPlanContributionsByEmployer_D92FF95F1F68A13D97411977068775D5" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Defined benefit plan, contributions by employer</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DefinedBenefitPlanContributionsByEmployer" xlink:label="loc_us-gaap_DefinedBenefitPlanContributionsByEmployer_D92FF95F1F68A13D97411977068775D5" xlink:type="locator" />
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    <link:label id="lab_iart_TermOfLease_3C96E432F9B126A75E0455285A244A21_label_en-US" xlink:label="lab_iart_TermOfLease_3C96E432F9B126A75E0455285A244A21" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Term Of Lease</link:label>
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    <link:label id="lab_iart_OptionToRenewLease_1D9FB1A2D17FB1A983DE55285A2459C2_label_en-US" xlink:label="lab_iart_OptionToRenewLease_1D9FB1A2D17FB1A983DE55285A2459C2" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Option To Renew Lease</link:label>
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    <link:loc xlink:href="iart-20151231.xsd#iart_OptionToRenewLease" xlink:label="loc_iart_OptionToRenewLease_1D9FB1A2D17FB1A983DE55285A2459C2" xlink:type="locator" />
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    <link:label id="lab_iart_PaymentPerYearToRelatedPartyLessor_6CA0400FD916EA11B1BF55285A24E6E2_terseLabel_en-US" xlink:label="lab_iart_PaymentPerYearToRelatedPartyLessor_6CA0400FD916EA11B1BF55285A24E6E2" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Payment per year to related party lessor</link:label>
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    <link:label id="lab_iart_PercentOfManufacturingFacilityOwnedByCorporationWhoseShareholdersAreTrustsWhoseBeneficiariesIncludeFamilyMembersOfCompanysFormerChairman_C75B8DF8F26C97CE6B6955285A2415A3_verboseLabel_en-US" xlink:label="lab_iart_PercentOfManufacturingFacilityOwnedByCorporationWhoseShareholdersAreTrustsWhoseBeneficiariesIncludeFamilyMembersOfCompanysFormerChairman_C75B8DF8F26C97CE6B6955285A2415A3" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Percent of manufacturing facility owned by corporation whose shareholders are trusts whose beneficiaries include family members of company's former chairman</link:label>
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    <link:label id="lab_iart_AnnualRateOfLeaseAgreement_7C24C08C4A616B40803455285A25D33C_terseLabel_en-US" xlink:label="lab_iart_AnnualRateOfLeaseAgreement_7C24C08C4A616B40803455285A25D33C" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Annual rate of lease agreement</link:label>
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