<?xml version="1.0" encoding="US-ASCII"?>
<!--XBRL Document Created with Wdesk from Workiva-->
<!-- -->
<linkbase xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" xmlns="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <roleRef roleURI="http://integralife.com/role/AccumulatedOtherComprehensiveIncomeLoss" xlink:href="iart-20151231.xsd#AccumulatedOtherComprehensiveIncomeLoss" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/AccumulatedOtherComprehensiveIncomeLossReclassificationOutOfAccumulatedOtherComprehensiveIncomeDetails" xlink:href="iart-20151231.xsd#AccumulatedOtherComprehensiveIncomeLossReclassificationOutOfAccumulatedOtherComprehensiveIncomeDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/AccumulatedOtherComprehensiveIncomeLossScheduleOfAccumulatedOtherComprehensiveIncomeLossDetails" xlink:href="iart-20151231.xsd#AccumulatedOtherComprehensiveIncomeLossScheduleOfAccumulatedOtherComprehensiveIncomeLossDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/AccumulatedOtherComprehensiveIncomeLossTables" xlink:href="iart-20151231.xsd#AccumulatedOtherComprehensiveIncomeLossTables" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/AcquisitionsAndProFormaResults" xlink:href="iart-20151231.xsd#AcquisitionsAndProFormaResults" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/AcquisitionsAndProFormaResultsNarrativeDetails" xlink:href="iart-20151231.xsd#AcquisitionsAndProFormaResultsNarrativeDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/AcquisitionsAndProFormaResultsProFormaFinancialInformationSummarizationResultsOfOperationsDetails" xlink:href="iart-20151231.xsd#AcquisitionsAndProFormaResultsProFormaFinancialInformationSummarizationResultsOfOperationsDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/AcquisitionsAndProFormaResultsRollForwardOfContingentConsiderationLiabilityForPurchaseOfTarsusMedicalDetails" xlink:href="iart-20151231.xsd#AcquisitionsAndProFormaResultsRollForwardOfContingentConsiderationLiabilityForPurchaseOfTarsusMedicalDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/AcquisitionsAndProFormaResultsScheduleOfAssetsAcquiredAndLiabilitiesAssumedDetails" xlink:href="iart-20151231.xsd#AcquisitionsAndProFormaResultsScheduleOfAssetsAcquiredAndLiabilitiesAssumedDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/AcquisitionsAndProFormaResultsTables" xlink:href="iart-20151231.xsd#AcquisitionsAndProFormaResultsTables" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/Business" xlink:href="iart-20151231.xsd#Business" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/CommitmentsAndContingencies" xlink:href="iart-20151231.xsd#CommitmentsAndContingencies" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/CommitmentsAndContingenciesDetails" xlink:href="iart-20151231.xsd#CommitmentsAndContingenciesDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/ConsolidatedBalanceSheets" xlink:href="iart-20151231.xsd#ConsolidatedBalanceSheets" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:href="iart-20151231.xsd#ConsolidatedBalanceSheetsParenthetical" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/ConsolidatedStatementsOfCashFlows" xlink:href="iart-20151231.xsd#ConsolidatedStatementsOfCashFlows" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/ConsolidatedStatementsOfChangesInStockholdersEquity" xlink:href="iart-20151231.xsd#ConsolidatedStatementsOfChangesInStockholdersEquity" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/ConsolidatedStatementsOfComprehensiveIncomeLoss" xlink:href="iart-20151231.xsd#ConsolidatedStatementsOfComprehensiveIncomeLoss" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/ConsolidatedStatementsOfOperations" xlink:href="iart-20151231.xsd#ConsolidatedStatementsOfOperations" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/Debt" xlink:href="iart-20151231.xsd#Debt" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/DebtComponentsOfInterestExpenseDetails" xlink:href="iart-20151231.xsd#DebtComponentsOfInterestExpenseDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/DebtNarrativeDetails" xlink:href="iart-20151231.xsd#DebtNarrativeDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/DebtScheduleOfDebtMaturityDetails" xlink:href="iart-20151231.xsd#DebtScheduleOfDebtMaturityDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/DebtTables" xlink:href="iart-20151231.xsd#DebtTables" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/DerivativeInstruments" xlink:href="iart-20151231.xsd#DerivativeInstruments" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/DerivativeInstrumentsEffectOfDerivativeInstrumentsDesignatedCashFlowHedgesOnStatementsOfOperationsDetails" xlink:href="iart-20151231.xsd#DerivativeInstrumentsEffectOfDerivativeInstrumentsDesignatedCashFlowHedgesOnStatementsOfOperationsDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/DerivativeInstrumentsNarrativeDetails" xlink:href="iart-20151231.xsd#DerivativeInstrumentsNarrativeDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/DerivativeInstrumentsSummaryOfFairValueInBalanceSheetForDerivativesDesignatedHedgingInstrumentsDetails" xlink:href="iart-20151231.xsd#DerivativeInstrumentsSummaryOfFairValueInBalanceSheetForDerivativesDesignatedHedgingInstrumentsDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/DerivativeInstrumentsTables" xlink:href="iart-20151231.xsd#DerivativeInstrumentsTables" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/DiscontinuedOperations" xlink:href="iart-20151231.xsd#DiscontinuedOperations" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/DiscontinuedOperationsNarrativeDetails" xlink:href="iart-20151231.xsd#DiscontinuedOperationsNarrativeDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/DiscontinuedOperationsSummaryOfAssetsAndLiabilitiesDiscontinuedOperationsDetails" xlink:href="iart-20151231.xsd#DiscontinuedOperationsSummaryOfAssetsAndLiabilitiesDiscontinuedOperationsDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/DiscontinuedOperationsSummaryOfStatementsOfOperationsDiscontinuedOperationsDetails" xlink:href="iart-20151231.xsd#DiscontinuedOperationsSummaryOfStatementsOfOperationsDiscontinuedOperationsDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/DiscontinuedOperationsTables" xlink:href="iart-20151231.xsd#DiscontinuedOperationsTables" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/DocumentAndEntityInformation" xlink:href="iart-20151231.xsd#DocumentAndEntityInformation" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/IncomeTaxes" xlink:href="iart-20151231.xsd#IncomeTaxes" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/IncomeTaxesNarrativeDetails" xlink:href="iart-20151231.xsd#IncomeTaxesNarrativeDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/IncomeTaxesScheduleOfDeferredTaxAssetsAndLiabilitiesDetails" xlink:href="iart-20151231.xsd#IncomeTaxesScheduleOfDeferredTaxAssetsAndLiabilitiesDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/IncomeTaxesScheduleOfEffectiveTaxRateReconciliationDetails" xlink:href="iart-20151231.xsd#IncomeTaxesScheduleOfEffectiveTaxRateReconciliationDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/IncomeTaxesScheduleOfIncomeBeforeIncomeTaxesDetails" xlink:href="iart-20151231.xsd#IncomeTaxesScheduleOfIncomeBeforeIncomeTaxesDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/IncomeTaxesScheduleOfProvisionForIncomeTaxesDetails" xlink:href="iart-20151231.xsd#IncomeTaxesScheduleOfProvisionForIncomeTaxesDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/IncomeTaxesScheduleOfUncertainTaxBenefitsReconciliationDetails" xlink:href="iart-20151231.xsd#IncomeTaxesScheduleOfUncertainTaxBenefitsReconciliationDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/IncomeTaxesTables" xlink:href="iart-20151231.xsd#IncomeTaxesTables" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/LeasesAndRelatedPartyLeases" xlink:href="iart-20151231.xsd#LeasesAndRelatedPartyLeases" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/LeasesAndRelatedPartyLeasesNarrativeDetails" xlink:href="iart-20151231.xsd#LeasesAndRelatedPartyLeasesNarrativeDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/LeasesAndRelatedPartyLeasesScheduleOfFutureMinimumLeasePaymentsForCapitalLeasesDetails" xlink:href="iart-20151231.xsd#LeasesAndRelatedPartyLeasesScheduleOfFutureMinimumLeasePaymentsForCapitalLeasesDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/LeasesAndRelatedPartyLeasesScheduleOfMinimumLeasePaymentsDetails" xlink:href="iart-20151231.xsd#LeasesAndRelatedPartyLeasesScheduleOfMinimumLeasePaymentsDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/LeasesAndRelatedPartyLeasesTables" xlink:href="iart-20151231.xsd#LeasesAndRelatedPartyLeasesTables" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/NetLossIncomePerShare" xlink:href="iart-20151231.xsd#NetLossIncomePerShare" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/NetLossIncomePerShareBasicAndDilutedNetIncomePerShareDetails" xlink:href="iart-20151231.xsd#NetLossIncomePerShareBasicAndDilutedNetIncomePerShareDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/NetLossIncomePerShareNarrativeDetails" xlink:href="iart-20151231.xsd#NetLossIncomePerShareNarrativeDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/NetLossIncomePerShareTables" xlink:href="iart-20151231.xsd#NetLossIncomePerShareTables" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/RetirementBenefitPlans" xlink:href="iart-20151231.xsd#RetirementBenefitPlans" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/RetirementBenefitPlansChangesInProjectedBenefitObligationAndFairValueOfPlanAssetsDetails" xlink:href="iart-20151231.xsd#RetirementBenefitPlansChangesInProjectedBenefitObligationAndFairValueOfPlanAssetsDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/RetirementBenefitPlansNarrativeDetails" xlink:href="iart-20151231.xsd#RetirementBenefitPlansNarrativeDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/ScheduleIiValuationAndQualifyingAccounts" xlink:href="iart-20151231.xsd#ScheduleIiValuationAndQualifyingAccounts" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/ScheduleIiValuationAndQualifyingAccountsDetails" xlink:href="iart-20151231.xsd#ScheduleIiValuationAndQualifyingAccountsDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/SegmentAndGeographicInformation" xlink:href="iart-20151231.xsd#SegmentAndGeographicInformation" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/SegmentAndGeographicInformationNarrativeDetails" xlink:href="iart-20151231.xsd#SegmentAndGeographicInformationNarrativeDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/SegmentAndGeographicInformationNetSalesAndProfitByReportableSegmentDetails" xlink:href="iart-20151231.xsd#SegmentAndGeographicInformationNetSalesAndProfitByReportableSegmentDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/SegmentAndGeographicInformationTables" xlink:href="iart-20151231.xsd#SegmentAndGeographicInformationTables" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/SegmentAndGeographicInformationTotalRevenueByMajorGeographicAreaDetails" xlink:href="iart-20151231.xsd#SegmentAndGeographicInformationTotalRevenueByMajorGeographicAreaDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/SelectedQuarterlyInformationUnaudited" xlink:href="iart-20151231.xsd#SelectedQuarterlyInformationUnaudited" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/SelectedQuarterlyInformationUnauditedSelectedQuarterlyInformationDetails" xlink:href="iart-20151231.xsd#SelectedQuarterlyInformationUnauditedSelectedQuarterlyInformationDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/SelectedQuarterlyInformationUnauditedTables" xlink:href="iart-20151231.xsd#SelectedQuarterlyInformationUnauditedTables" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/StockBasedCompensation" xlink:href="iart-20151231.xsd#StockBasedCompensation" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/StockBasedCompensationNarrativeDetails" xlink:href="iart-20151231.xsd#StockBasedCompensationNarrativeDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/StockBasedCompensationSummaryOfEmployeeStockBasedCompensationExpenseDetails" xlink:href="iart-20151231.xsd#StockBasedCompensationSummaryOfEmployeeStockBasedCompensationExpenseDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/StockBasedCompensationSummaryOfStockOptionActivityDetails" xlink:href="iart-20151231.xsd#StockBasedCompensationSummaryOfStockOptionActivityDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/StockBasedCompensationSummaryOfVestedAndUnvestedRsuDetails" xlink:href="iart-20151231.xsd#StockBasedCompensationSummaryOfVestedAndUnvestedRsuDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/StockBasedCompensationSummaryOfWeightedAverageAssumptionsDetails" xlink:href="iart-20151231.xsd#StockBasedCompensationSummaryOfWeightedAverageAssumptionsDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/StockBasedCompensationTables" xlink:href="iart-20151231.xsd#StockBasedCompensationTables" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/SummaryOfSignificantAccountingPolicies" xlink:href="iart-20151231.xsd#SummaryOfSignificantAccountingPolicies" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/SummaryOfSignificantAccountingPoliciesComponentsOfCompanysIdentifiableIntangibleAssetsDetails" xlink:href="iart-20151231.xsd#SummaryOfSignificantAccountingPoliciesComponentsOfCompanysIdentifiableIntangibleAssetsDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/SummaryOfSignificantAccountingPoliciesNarrativeDetails" xlink:href="iart-20151231.xsd#SummaryOfSignificantAccountingPoliciesNarrativeDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/SummaryOfSignificantAccountingPoliciesPolicies" xlink:href="iart-20151231.xsd#SummaryOfSignificantAccountingPoliciesPolicies" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/SummaryOfSignificantAccountingPoliciesScheduleOfChangesInAccountingEstimateDetails" xlink:href="iart-20151231.xsd#SummaryOfSignificantAccountingPoliciesScheduleOfChangesInAccountingEstimateDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/SummaryOfSignificantAccountingPoliciesScheduleOfChangesInCarryingAmountOfGoodwillDetails" xlink:href="iart-20151231.xsd#SummaryOfSignificantAccountingPoliciesScheduleOfChangesInCarryingAmountOfGoodwillDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/SummaryOfSignificantAccountingPoliciesScheduleOfInventoriesNetDetails" xlink:href="iart-20151231.xsd#SummaryOfSignificantAccountingPoliciesScheduleOfInventoriesNetDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/SummaryOfSignificantAccountingPoliciesScheduleOfPropertyPlantAndEquipmentBalancesAndCorrespondingLivesDetails" xlink:href="iart-20151231.xsd#SummaryOfSignificantAccountingPoliciesScheduleOfPropertyPlantAndEquipmentBalancesAndCorrespondingLivesDetails" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/SummaryOfSignificantAccountingPoliciesTables" xlink:href="iart-20151231.xsd#SummaryOfSignificantAccountingPoliciesTables" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/TreasuryStock" xlink:href="iart-20151231.xsd#TreasuryStock" xlink:type="simple" />
  <roleRef roleURI="http://integralife.com/role/TreasuryStockNarrativeDetails" xlink:href="iart-20151231.xsd#TreasuryStockNarrativeDetails" xlink:type="simple" />
  <roleRef roleURI="http://www.xbrl.org/2009/role/negatedLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedLabel" xlink:type="simple" />
  <roleRef roleURI="http://www.xbrl.org/2009/role/negatedNetLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedNetLabel" xlink:type="simple" />
  <roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodEndLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodEndLabel" xlink:type="simple" />
  <roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodStartLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodStartLabel" xlink:type="simple" />
  <roleRef roleURI="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTerseLabel" xlink:type="simple" />
  <roleRef roleURI="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTotalLabel" xlink:type="simple" />
  <roleRef roleURI="http://www.xbrl.org/2009/role/netLabel" xlink:href="http://www.xbrl.org/lrr/role/net-2009-12-16.xsd#netLabel" xlink:type="simple" />
  <presentationLink xlink:role="http://integralife.com/role/AccumulatedOtherComprehensiveIncomeLoss" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_9C8D1976CFBB2C12217F5EFBC1FA87B7" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ComprehensiveIncomeNoteTextBlock" xlink:label="loc_us-gaap_ComprehensiveIncomeNoteTextBlock_71062C334D165DA1AA4D5EFAE2993D14" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_9C8D1976CFBB2C12217F5EFBC1FA87B7" xlink:to="loc_us-gaap_ComprehensiveIncomeNoteTextBlock_71062C334D165DA1AA4D5EFAE2993D14" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/AccumulatedOtherComprehensiveIncomeLossReclassificationOutOfAccumulatedOtherComprehensiveIncomeDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_220E65FD75B3C4A188AB153928208AA9" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_089A9DFA679BC84D5B3715392820B9A4" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_220E65FD75B3C4A188AB153928208AA9" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_089A9DFA679BC84D5B3715392820B9A4" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_A3F08FFCC5A25F4815B6153928209858" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_089A9DFA679BC84D5B3715392820B9A4" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_A3F08FFCC5A25F4815B6153928209858" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_ECE6D2D42AFDF49E86D4153928205E9E" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_A3F08FFCC5A25F4815B6153928209858" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_ECE6D2D42AFDF49E86D4153928205E9E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InterestRateSwapMember" xlink:label="loc_us-gaap_InterestRateSwapMember_FF84501B7C85A78F125D153928204C06" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_ECE6D2D42AFDF49E86D4153928205E9E" xlink:to="loc_us-gaap_InterestRateSwapMember_FF84501B7C85A78F125D153928204C06" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_E86B5B7D2AC6CA9A406F1539282022E2" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_089A9DFA679BC84D5B3715392820B9A4" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_E86B5B7D2AC6CA9A406F1539282022E2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_2734566C39DD6886AD80153928200874" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_E86B5B7D2AC6CA9A406F1539282022E2" xlink:to="loc_us-gaap_EquityComponentDomain_2734566C39DD6886AD80153928200874" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccumulatedNetGainLossFromDesignatedOrQualifyingCashFlowHedgesMember" xlink:label="loc_us-gaap_AccumulatedNetGainLossFromDesignatedOrQualifyingCashFlowHedgesMember_6DB4F63FC6CC9CBEB935153928210872" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_2734566C39DD6886AD80153928200874" xlink:to="loc_us-gaap_AccumulatedNetGainLossFromDesignatedOrQualifyingCashFlowHedgesMember_6DB4F63FC6CC9CBEB935153928210872" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_589EBA330DA3ED8BDDE3153928216DB2" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_089A9DFA679BC84D5B3715392820B9A4" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_589EBA330DA3ED8BDDE3153928216DB2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_59C18A630A1E38EA4CFA153928262362" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_589EBA330DA3ED8BDDE3153928216DB2" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_59C18A630A1E38EA4CFA153928262362" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember_2CC8B92AC6AAD602814A15392827DA60" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_59C18A630A1E38EA4CFA153928262362" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember_2CC8B92AC6AAD602814A15392827DA60" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems" xlink:label="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_9D15736FC49DC4A2AB47153928275A5F" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTable_089A9DFA679BC84D5B3715392820B9A4" xlink:to="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_9D15736FC49DC4A2AB47153928275A5F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InterestExpense" xlink:label="loc_us-gaap_InterestExpense_4BD9FEF313F6B8ED7896153928279384" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_9D15736FC49DC4A2AB47153928275A5F" xlink:to="loc_us-gaap_InterestExpense_4BD9FEF313F6B8ED7896153928279384" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CostOfGoodsSold" xlink:label="loc_us-gaap_CostOfGoodsSold_F49E050FC2D5E8448963153928275042" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_9D15736FC49DC4A2AB47153928275A5F" xlink:to="loc_us-gaap_CostOfGoodsSold_F49E050FC2D5E8448963153928275042" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_EBA61E4EDE2DD3448DFC1539282769A5" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_9D15736FC49DC4A2AB47153928275A5F" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_EBA61E4EDE2DD3448DFC1539282769A5" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_434EA856759A4144793B153928275A0E" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReclassificationAdjustmentOutOfAccumulatedOtherComprehensiveIncomeLineItems_9D15736FC49DC4A2AB47153928275A5F" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_434EA856759A4144793B153928275A0E" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/AccumulatedOtherComprehensiveIncomeLossScheduleOfAccumulatedOtherComprehensiveIncomeLossDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_3D263EBB848BB0B40A7D5F005F063C11" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossTable" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_4EA021FE0A05B6502CE75EFAE28A145E" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_3D263EBB848BB0B40A7D5F005F063C11" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_4EA021FE0A05B6502CE75EFAE28A145E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_8DA53968D05E282E673A5EFAE28FEC80" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_4EA021FE0A05B6502CE75EFAE28A145E" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_8DA53968D05E282E673A5EFAE28FEC80" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_927C0A8F72B1EDB6FF7C5EFAE28F983A" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_8DA53968D05E282E673A5EFAE28FEC80" xlink:to="loc_us-gaap_EquityComponentDomain_927C0A8F72B1EDB6FF7C5EFAE28F983A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccumulatedNetGainLossFromDesignatedOrQualifyingCashFlowHedgesMember" xlink:label="loc_us-gaap_AccumulatedNetGainLossFromDesignatedOrQualifyingCashFlowHedgesMember_41DF846ECDAC369BB6475EFAE290E7D5" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_927C0A8F72B1EDB6FF7C5EFAE28F983A" xlink:to="loc_us-gaap_AccumulatedNetGainLossFromDesignatedOrQualifyingCashFlowHedgesMember_41DF846ECDAC369BB6475EFAE290E7D5" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccumulatedDefinedBenefitPlansAdjustmentMember" xlink:label="loc_us-gaap_AccumulatedDefinedBenefitPlansAdjustmentMember_45696833C7993E4AB49A5EFAE29020A1" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_927C0A8F72B1EDB6FF7C5EFAE28F983A" xlink:to="loc_us-gaap_AccumulatedDefinedBenefitPlansAdjustmentMember_45696833C7993E4AB49A5EFAE29020A1" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccumulatedTranslationAdjustmentMember" xlink:label="loc_us-gaap_AccumulatedTranslationAdjustmentMember_2B2E616D93EEA717B6E15EFAE290A819" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_927C0A8F72B1EDB6FF7C5EFAE28F983A" xlink:to="loc_us-gaap_AccumulatedTranslationAdjustmentMember_2B2E616D93EEA717B6E15EFAE290A819" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_97BFBC12613841506DFD5EFAE2908DA2" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_4EA021FE0A05B6502CE75EFAE28A145E" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_97BFBC12613841506DFD5EFAE2908DA2" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_AccumulatedOtherComprehensiveIncomeLossRollForward" xlink:label="loc_iart_AccumulatedOtherComprehensiveIncomeLossRollForward_5012C6FA78202F4A710D5EFAE29026FC" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_97BFBC12613841506DFD5EFAE2908DA2" xlink:to="loc_iart_AccumulatedOtherComprehensiveIncomeLossRollForward_5012C6FA78202F4A710D5EFAE29026FC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_C68EB5EFD199CBDC161E5EFAE290112B" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_AccumulatedOtherComprehensiveIncomeLossRollForward_5012C6FA78202F4A710D5EFAE29026FC" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_C68EB5EFD199CBDC161E5EFAE290112B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax_7CEA63FC22370E9D4E1B5EFAE290D064" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_AccumulatedOtherComprehensiveIncomeLossRollForward_5012C6FA78202F4A710D5EFAE29026FC" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax_7CEA63FC22370E9D4E1B5EFAE290D064" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax" xlink:label="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_706D1EECC6A90EC118DD5EFAE29067C2" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_AccumulatedOtherComprehensiveIncomeLossRollForward_5012C6FA78202F4A710D5EFAE29026FC" xlink:to="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_706D1EECC6A90EC118DD5EFAE29067C2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_4AF7CB9DA911A4FDB0055EFAE29033CC" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_AccumulatedOtherComprehensiveIncomeLossRollForward_5012C6FA78202F4A710D5EFAE29026FC" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_4AF7CB9DA911A4FDB0055EFAE29033CC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_C1069C2B9D3974ACAE2D5EFAE290060C" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_AccumulatedOtherComprehensiveIncomeLossRollForward_5012C6FA78202F4A710D5EFAE29026FC" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_C1069C2B9D3974ACAE2D5EFAE290060C" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/AccumulatedOtherComprehensiveIncomeLossTables" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_4BED026AFB2FD34340195EFE9AB2E3EF" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock_8C442E0BA5FEBF0F52415EFAE292BB0F" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_4BED026AFB2FD34340195EFE9AB2E3EF" xlink:to="loc_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock_8C442E0BA5FEBF0F52415EFAE292BB0F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock_75F7FDD9ED5B59D681265EFAE292A6FF" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_4BED026AFB2FD34340195EFE9AB2E3EF" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeTableTextBlock_75F7FDD9ED5B59D681265EFAE292A6FF" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/AcquisitionsAndProFormaResults" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationsAbstract" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_A9878D4EC379527DD60555ED59EA42F7" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationDisclosureTextBlock" xlink:label="loc_us-gaap_BusinessCombinationDisclosureTextBlock_DDFE48F6954A7E7DD44355ED59EAC5DA" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_A9878D4EC379527DD60555ED59EA42F7" xlink:to="loc_us-gaap_BusinessCombinationDisclosureTextBlock_DDFE48F6954A7E7DD44355ED59EAC5DA" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/AcquisitionsAndProFormaResultsNarrativeDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationsAbstract" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_8B3DB8BD3EACE49377E5093FF84B8A05" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_B0955CD88B063196159A093FF84CE29A" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_8B3DB8BD3EACE49377E5093FF84B8A05" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_B0955CD88B063196159A093FF84CE29A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_A1282D35B539EB7B7504093FF84C2F22" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_B0955CD88B063196159A093FF84CE29A" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_A1282D35B539EB7B7504093FF84C2F22" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_95ACF93E29EB9EDD0057093FF84CF964" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_A1282D35B539EB7B7504093FF84C2F22" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_95ACF93E29EB9EDD0057093FF84CF964" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherIncomeMember" xlink:label="loc_us-gaap_OtherIncomeMember_BA5CEFDF000E69F6B55A093FF84CE0D6" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_95ACF93E29EB9EDD0057093FF84CF964" xlink:to="loc_us-gaap_OtherIncomeMember_BA5CEFDF000E69F6B55A093FF84CE0D6" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SellingGeneralAndAdministrativeMember" xlink:label="loc_iart_SellingGeneralAndAdministrativeMember_5996D602DE81866225F8094480035F75" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_95ACF93E29EB9EDD0057093FF84CF964" xlink:to="loc_iart_SellingGeneralAndAdministrativeMember_5996D602DE81866225F8094480035F75" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_7CF8DE28592D4D1FB7E9093FF84C6EA2" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_B0955CD88B063196159A093FF84CE29A" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_7CF8DE28592D4D1FB7E9093FF84C6EA2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_26EC39089274A353F6ED093FF84C998F" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_7CF8DE28592D4D1FB7E9093FF84C6EA2" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_26EC39089274A353F6ED093FF84C998F" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TekmedMember" xlink:label="loc_iart_TekmedMember_BA583BB4A0D0CF977508093FF84CFA30" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_26EC39089274A353F6ED093FF84C998F" xlink:to="loc_iart_TekmedMember_BA583BB4A0D0CF977508093FF84CFA30" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SaltoandFuturaMember" xlink:label="loc_iart_SaltoandFuturaMember_E69381D67866F9E22C20093FF84C4D86" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_26EC39089274A353F6ED093FF84C998F" xlink:to="loc_iart_SaltoandFuturaMember_E69381D67866F9E22C20093FF84C4D86" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TEIMember" xlink:label="loc_iart_TEIMember_7EF1C3DDB6645AECB7BC093FF84C82B7" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_26EC39089274A353F6ED093FF84C998F" xlink:to="loc_iart_TEIMember_7EF1C3DDB6645AECB7BC093FF84C82B7" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TEIBiosciencesInc.Member" xlink:label="loc_iart_TEIBiosciencesInc.Member_1BC13B81E715807C23C4093FF84C82BC" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_26EC39089274A353F6ED093FF84C998F" xlink:to="loc_iart_TEIBiosciencesInc.Member_1BC13B81E715807C23C4093FF84C82BC" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TEIMedicalInc.Member" xlink:label="loc_iart_TEIMedicalInc.Member_707B583068EC80C7C814093FF84C2418" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_26EC39089274A353F6ED093FF84C998F" xlink:to="loc_iart_TEIMedicalInc.Member_707B583068EC80C7C814093FF84C2418" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_MetasurgMember" xlink:label="loc_iart_MetasurgMember_2C807E06A38A43E58599093FF84CC2B1" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_26EC39089274A353F6ED093FF84C998F" xlink:to="loc_iart_MetasurgMember_2C807E06A38A43E58599093FF84CC2B1" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_MedtronicMicroFranceMember" xlink:label="loc_iart_MedtronicMicroFranceMember_4AF65BA5BB398C5FE314093FF84C3C30" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_26EC39089274A353F6ED093FF84C998F" xlink:to="loc_iart_MedtronicMicroFranceMember_4AF65BA5BB398C5FE314093FF84C3C30" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_ConfluentSurgicalInc.Member" xlink:label="loc_iart_ConfluentSurgicalInc.Member_EE7F5FB2A3959CA7036B093FF84D3051" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_26EC39089274A353F6ED093FF84C998F" xlink:to="loc_iart_ConfluentSurgicalInc.Member_EE7F5FB2A3959CA7036B093FF84D3051" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TarsusMedicalIncMember" xlink:label="loc_iart_TarsusMedicalIncMember_F94E08C68FA7B092001F093FF84D19E0" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_26EC39089274A353F6ED093FF84C998F" xlink:to="loc_iart_TarsusMedicalIncMember_F94E08C68FA7B092001F093FF84D19E0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ContingentConsiderationByTypeAxis" xlink:label="loc_us-gaap_ContingentConsiderationByTypeAxis_CCF23365E37D5BA634A4093FF84DFD49" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_B0955CD88B063196159A093FF84CE29A" xlink:to="loc_us-gaap_ContingentConsiderationByTypeAxis_CCF23365E37D5BA634A4093FF84DFD49" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ContingentConsiderationTypeDomain" xlink:label="loc_us-gaap_ContingentConsiderationTypeDomain_6B38EE27B7EF0F7B2B10093FF84DA81C" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContingentConsiderationByTypeAxis_CCF23365E37D5BA634A4093FF84DFD49" xlink:to="loc_us-gaap_ContingentConsiderationTypeDomain_6B38EE27B7EF0F7B2B10093FF84DA81C" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_CashConsiderationOneMember" xlink:label="loc_iart_CashConsiderationOneMember_9F56C68A04E54504F35A093FF84D4BA5" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContingentConsiderationTypeDomain_6B38EE27B7EF0F7B2B10093FF84DA81C" xlink:to="loc_iart_CashConsiderationOneMember_9F56C68A04E54504F35A093FF84D4BA5" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_CashConsiderationTwoMember" xlink:label="loc_iart_CashConsiderationTwoMember_B0DAAB974E0C5351F7A1093FF84D1685" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContingentConsiderationTypeDomain_6B38EE27B7EF0F7B2B10093FF84DA81C" xlink:to="loc_iart_CashConsiderationTwoMember_B0DAAB974E0C5351F7A1093FF84D1685" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BalanceSheetLocationAxis" xlink:label="loc_us-gaap_BalanceSheetLocationAxis_F8B862918582DF0626BF093FF84D60B0" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_B0955CD88B063196159A093FF84CE29A" xlink:to="loc_us-gaap_BalanceSheetLocationAxis_F8B862918582DF0626BF093FF84D60B0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BalanceSheetLocationDomain" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_AD1122944463BE316461093FF84D1D7A" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_F8B862918582DF0626BF093FF84D60B0" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_AD1122944463BE316461093FF84D1D7A" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DeferredTaxLiabilityMember" xlink:label="loc_iart_DeferredTaxLiabilityMember_CEC920E8211324190B29093FF84D1FE8" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_AD1122944463BE316461093FF84D1D7A" xlink:to="loc_iart_DeferredTaxLiabilityMember_CEC920E8211324190B29093FF84D1FE8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_B0955CD88B063196159A093FF84CE29A" xlink:to="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationConsiderationTransferred1" xlink:label="loc_us-gaap_BusinessCombinationConsiderationTransferred1_D494FFB3586FC4A78FE5093FF84D3701" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_us-gaap_BusinessCombinationConsiderationTransferred1_D494FFB3586FC4A78FE5093FF84D3701" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationProFormaInformationRevenueOfAcquireeSinceAcquisitionDateActual" xlink:label="loc_us-gaap_BusinessCombinationProFormaInformationRevenueOfAcquireeSinceAcquisitionDateActual_2A88652705179B428888093FF84DFBB0" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_us-gaap_BusinessCombinationProFormaInformationRevenueOfAcquireeSinceAcquisitionDateActual_2A88652705179B428888093FF84DFBB0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesGross" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesGross_7EC656EDC8C67BAD51C6093FF84E9E5B" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesGross_7EC656EDC8C67BAD51C6093FF84E9E5B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationBargainPurchaseGainRecognizedAmount" xlink:label="loc_us-gaap_BusinessCombinationBargainPurchaseGainRecognizedAmount_8CB0B69F0F621A70F495093FF84E0094" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_us-gaap_BusinessCombinationBargainPurchaseGainRecognizedAmount_8CB0B69F0F621A70F495093FF84E0094" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NumberOfBusinessesAcquired" xlink:label="loc_us-gaap_NumberOfBusinessesAcquired_2205569DF41BEB5EA48E093FF84E30A7" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_us-gaap_NumberOfBusinessesAcquired_2205569DF41BEB5EA48E093FF84E30A7" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_799C40C2798F11F85540093FF84E5C27" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_799C40C2798F11F85540093FF84E5C27" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_A94612E92D19BAEF01D0093FF84EB871" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_A94612E92D19BAEF01D0093FF84EB871" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationAsset" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationAsset_84DC5F1EC85AB4DB0CD0093FF84E2DFA" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationAsset_84DC5F1EC85AB4DB0CD0093FF84E2DFA" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_BusinessCombinationContingentConsiderationAssetRevenueThresholdToRealizeAsset" xlink:label="loc_iart_BusinessCombinationContingentConsiderationAssetRevenueThresholdToRealizeAsset_CA0CE75F8BD0D21BD837093FF84EF919" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_iart_BusinessCombinationContingentConsiderationAssetRevenueThresholdToRealizeAsset_CA0CE75F8BD0D21BD837093FF84EF919" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_56F4B4E44AC47D9F5322093FF84E75C3" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_56F4B4E44AC47D9F5322093FF84E75C3" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh_39755D49CB21C1E81810093FF84E2D52" xlink:type="locator" />
    <presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh_39755D49CB21C1E81810093FF84E2D52" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FairValueInputsDiscountRate" xlink:label="loc_us-gaap_FairValueInputsDiscountRate_A4D3F3F6A283308660F3093FF84F9A42" xlink:type="locator" />
    <presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_us-gaap_FairValueInputsDiscountRate_A4D3F3F6A283308660F3093FF84F9A42" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_D0A3924AE929EA0A33C90942EB580321" xlink:type="locator" />
    <presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_D0A3924AE929EA0A33C90942EB580321" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentConsiderationTransferred" xlink:label="loc_us-gaap_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentConsiderationTransferred_E79A7FB06A7EA4D2BA3C093FF84F4DF1" xlink:type="locator" />
    <presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_us-gaap_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentConsiderationTransferred_E79A7FB06A7EA4D2BA3C093FF84F4DF1" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_67E6C8E66AF18F0D8150093FF84F850B" xlink:type="locator" />
    <presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_67E6C8E66AF18F0D8150093FF84F850B" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_PaymentstoAcquireBusinessesPaymentforBusinessInterest" xlink:label="loc_iart_PaymentstoAcquireBusinessesPaymentforBusinessInterest_8596AF0E9992F9D23AFC093FF84F22F3" xlink:type="locator" />
    <presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_iart_PaymentstoAcquireBusinessesPaymentforBusinessInterest_8596AF0E9992F9D23AFC093FF84F22F3" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_PaymentstoAcquireBusinessesPaymentsforTransitionalSupplyAgreement" xlink:label="loc_iart_PaymentstoAcquireBusinessesPaymentsforTransitionalSupplyAgreement_1FCADA1B4BBD1D026651093FF84FAAD7" xlink:type="locator" />
    <presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_iart_PaymentstoAcquireBusinessesPaymentsforTransitionalSupplyAgreement_1FCADA1B4BBD1D026651093FF84FAAD7" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_BusinessCombinationContingentConsiderationArrangementsArrangementExtensionPeriod" xlink:label="loc_iart_BusinessCombinationContingentConsiderationArrangementsArrangementExtensionPeriod_BAC143746351E4FCE18C093FF84F8A39" xlink:type="locator" />
    <presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_iart_BusinessCombinationContingentConsiderationArrangementsArrangementExtensionPeriod_BAC143746351E4FCE18C093FF84F8A39" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_BusinessCombinationContingentConsiderationArrangementsRequiredNumberofDaysforExtension" xlink:label="loc_iart_BusinessCombinationContingentConsiderationArrangementsRequiredNumberofDaysforExtension_E0CA66F97A29E305BBBE093FF84F24A6" xlink:type="locator" />
    <presentationArc order="19" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_iart_BusinessCombinationContingentConsiderationArrangementsRequiredNumberofDaysforExtension_E0CA66F97A29E305BBBE093FF84F24A6" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_BusinessCombinationContingentConsiderationArrangementsPeriodofContingentConsiderationArrangement" xlink:label="loc_iart_BusinessCombinationContingentConsiderationArrangementsPeriodofContingentConsiderationArrangement_826C45CDFFB8A8D5E387093FF84F533C" xlink:type="locator" />
    <presentationArc order="20" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_iart_BusinessCombinationContingentConsiderationArrangementsPeriodofContingentConsiderationArrangement_826C45CDFFB8A8D5E387093FF84F533C" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_BusinessCombinationsContingentConsiderationArrangementPeriodofTransitionalSupplyPriceIncreases" xlink:label="loc_iart_BusinessCombinationsContingentConsiderationArrangementPeriodofTransitionalSupplyPriceIncreases_62073EF14CDA120FD13D093FF84FF162" xlink:type="locator" />
    <presentationArc order="21" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_iart_BusinessCombinationsContingentConsiderationArrangementPeriodofTransitionalSupplyPriceIncreases_62073EF14CDA120FD13D093FF84FF162" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_GoodwillPurchaseAccountingAdjustments" xlink:label="loc_us-gaap_GoodwillPurchaseAccountingAdjustments_57B691047717DFD9C1C3093FF84F540D" xlink:type="locator" />
    <presentationArc order="22" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_us-gaap_GoodwillPurchaseAccountingAdjustments_57B691047717DFD9C1C3093FF84F540D" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_ImpairmentofIntangibleAssetsFinitelivedNumberofAssetsImpaired" xlink:label="loc_iart_ImpairmentofIntangibleAssetsFinitelivedNumberofAssetsImpaired_8109B91D04A71C099060093FF84F1797" xlink:type="locator" />
    <presentationArc order="23" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_iart_ImpairmentofIntangibleAssetsFinitelivedNumberofAssetsImpaired_8109B91D04A71C099060093FF84F1797" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsFinitelived" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsFinitelived_6548877E6880EA7E739A093FF84FBDFA" xlink:type="locator" />
    <presentationArc order="24" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsFinitelived_6548877E6880EA7E739A093FF84FBDFA" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_FairValueInputProbabilityofEvent" xlink:label="loc_iart_FairValueInputProbabilityofEvent_CC0AB32DAF757644527E093FF84F920E" xlink:type="locator" />
    <presentationArc order="25" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_iart_FairValueInputProbabilityofEvent_CC0AB32DAF757644527E093FF84F920E" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_BusinessCombinationContingentConsiderationArrangementsRangeofOutcomesValueIncrementalIncreaseinLiability" xlink:label="loc_iart_BusinessCombinationContingentConsiderationArrangementsRangeofOutcomesValueIncrementalIncreaseinLiability_FB81DA31DA0E1961068E093FF84FD633" xlink:type="locator" />
    <presentationArc order="26" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_iart_BusinessCombinationContingentConsiderationArrangementsRangeofOutcomesValueIncrementalIncreaseinLiability_FB81DA31DA0E1961068E093FF84FD633" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_BusinessCombinationContingentConsiderationArrangementsRangeofOutcomesValueIncrementalDecreaseinLiability" xlink:label="loc_iart_BusinessCombinationContingentConsiderationArrangementsRangeofOutcomesValueIncrementalDecreaseinLiability_36BDDD2000FCECDA65F0093FF84F42EE" xlink:type="locator" />
    <presentationArc order="27" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_iart_BusinessCombinationContingentConsiderationArrangementsRangeofOutcomesValueIncrementalDecreaseinLiability_36BDDD2000FCECDA65F0093FF84F42EE" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueLow" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueLow_38389D6674EF80869A52093FF84FD0ED" xlink:type="locator" />
    <presentationArc order="28" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_FCE5AD5ADB8AED1186CB093FF84DF406" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueLow_38389D6674EF80869A52093FF84FD0ED" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/AcquisitionsAndProFormaResultsProFormaFinancialInformationSummarizationResultsOfOperationsDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationsAbstract" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_2C211365E42E21F04F344FA9741E2D2C" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessAcquisitionsProFormaRevenue" xlink:label="loc_us-gaap_BusinessAcquisitionsProFormaRevenue_022388E63CC4779BDFEF4FA974202D6F" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_2C211365E42E21F04F344FA9741E2D2C" xlink:to="loc_us-gaap_BusinessAcquisitionsProFormaRevenue_022388E63CC4779BDFEF4FA974202D6F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessAcquisitionsProFormaNetIncomeLoss" xlink:label="loc_us-gaap_BusinessAcquisitionsProFormaNetIncomeLoss_7D3F802B358CDC4B6FE14FA97420F115" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_2C211365E42E21F04F344FA9741E2D2C" xlink:to="loc_us-gaap_BusinessAcquisitionsProFormaNetIncomeLoss_7D3F802B358CDC4B6FE14FA97420F115" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_us-gaap_EarningsPerShareAbstract_4E47D37896D27F6253ED4FA97420088E" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_2C211365E42E21F04F344FA9741E2D2C" xlink:to="loc_us-gaap_EarningsPerShareAbstract_4E47D37896D27F6253ED4FA97420088E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessAcquisitionProFormaEarningsPerShareBasic" xlink:label="loc_us-gaap_BusinessAcquisitionProFormaEarningsPerShareBasic_0A7B542AD2CE43B9B3464FA97420FDED" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_4E47D37896D27F6253ED4FA97420088E" xlink:to="loc_us-gaap_BusinessAcquisitionProFormaEarningsPerShareBasic_0A7B542AD2CE43B9B3464FA97420FDED" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/AcquisitionsAndProFormaResultsRollForwardOfContingentConsiderationLiabilityForPurchaseOfTarsusMedicalDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationsAbstract" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_74592791B32A04EA1E6C1977051AB958" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_3E191A434212FD24D0C01977051ACE6B" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_74592791B32A04EA1E6C1977051AB958" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_3E191A434212FD24D0C01977051ACE6B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_C610549C1CC55781445C1977051AFB41" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_3E191A434212FD24D0C01977051ACE6B" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_C610549C1CC55781445C1977051AFB41" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_E1944E82AAC0537930181977051ADAE2" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_C610549C1CC55781445C1977051AFB41" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_E1944E82AAC0537930181977051ADAE2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpensesMember" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_82301745057FD45FB8401977051AEFBA" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_E1944E82AAC0537930181977051ADAE2" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_82301745057FD45FB8401977051AEFBA" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_7D86AFEC17700985A7611977051AD084" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_3E191A434212FD24D0C01977051ACE6B" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_7D86AFEC17700985A7611977051AD084" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_48FA9A2FF2F1FBF500E31977051A3994" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_7D86AFEC17700985A7611977051AD084" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_48FA9A2FF2F1FBF500E31977051A3994" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_ConfluentSurgicalInc.Member" xlink:label="loc_iart_ConfluentSurgicalInc.Member_E0F86343A59862C911951977051AA769" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_48FA9A2FF2F1FBF500E31977051A3994" xlink:to="loc_iart_ConfluentSurgicalInc.Member_E0F86343A59862C911951977051AA769" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_MetasurgMember" xlink:label="loc_iart_MetasurgMember_214CEF8E4210CAA61E9C1977051AB7E3" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_48FA9A2FF2F1FBF500E31977051A3994" xlink:to="loc_iart_MetasurgMember_214CEF8E4210CAA61E9C1977051AB7E3" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_686CF05C7E9DCD4A83D21977051A85AB" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_3E191A434212FD24D0C01977051ACE6B" xlink:to="loc_us-gaap_BusinessAcquisitionLineItems_686CF05C7E9DCD4A83D21977051A85AB" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_BusinessAcquisitionContingentConsiderationRollForward" xlink:label="loc_iart_BusinessAcquisitionContingentConsiderationRollForward_B3D61C1A0AA26F8D78191977051B8CDD" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_686CF05C7E9DCD4A83D21977051A85AB" xlink:to="loc_iart_BusinessAcquisitionContingentConsiderationRollForward_B3D61C1A0AA26F8D78191977051B8CDD" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_7CE04E2869CF574AC66A1977051B9392" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_BusinessAcquisitionContingentConsiderationRollForward_B3D61C1A0AA26F8D78191977051B8CDD" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_7CE04E2869CF574AC66A1977051B9392" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_765F4005B7A1EAF8885D1977051BBBA2" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_BusinessAcquisitionContingentConsiderationRollForward_B3D61C1A0AA26F8D78191977051B8CDD" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_765F4005B7A1EAF8885D1977051BBBA2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_5D95F9765C7CBA41462C1977051B59C2" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_BusinessAcquisitionContingentConsiderationRollForward_B3D61C1A0AA26F8D78191977051B8CDD" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_5D95F9765C7CBA41462C1977051B59C2" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/AcquisitionsAndProFormaResultsScheduleOfAssetsAcquiredAndLiabilitiesAssumedDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationsAbstract" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_AD14652D6BF9766DA67618A8EEA318B6" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_94583135692978B3778718A8EEA36ABC" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_AD14652D6BF9766DA67618A8EEA318B6" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_94583135692978B3778718A8EEA36ABC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RangeAxis" xlink:label="loc_us-gaap_RangeAxis_8DF52497982CD08333D118A8EEA38EE0" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_94583135692978B3778718A8EEA36ABC" xlink:to="loc_us-gaap_RangeAxis_8DF52497982CD08333D118A8EEA38EE0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_A95C12CFDF6E31C8139318A8EEA44BBC" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeAxis_8DF52497982CD08333D118A8EEA38EE0" xlink:to="loc_us-gaap_RangeMember_A95C12CFDF6E31C8139318A8EEA44BBC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_MaximumMember" xlink:label="loc_us-gaap_MaximumMember_1F73E513A70461A711AC18A8EEA44366" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeMember_A95C12CFDF6E31C8139318A8EEA44BBC" xlink:to="loc_us-gaap_MaximumMember_1F73E513A70461A711AC18A8EEA44366" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_MinimumMember" xlink:label="loc_us-gaap_MinimumMember_6471E957A9BD1CA94D1318A8EEA47490" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeMember_A95C12CFDF6E31C8139318A8EEA44BBC" xlink:to="loc_us-gaap_MinimumMember_6471E957A9BD1CA94D1318A8EEA47490" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_F6397FB667600FE5E3CB18A8EEA4EE0E" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_94583135692978B3778718A8EEA36ABC" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_F6397FB667600FE5E3CB18A8EEA4EE0E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_4AF7B1CD7541C95DA20E18A8EEA40243" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_F6397FB667600FE5E3CB18A8EEA4EE0E" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_4AF7B1CD7541C95DA20E18A8EEA40243" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InProcessResearchAndDevelopmentMember" xlink:label="loc_us-gaap_InProcessResearchAndDevelopmentMember_F22EFCF9AEC56BA7F2A818A8EEA43366" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_4AF7B1CD7541C95DA20E18A8EEA40243" xlink:to="loc_us-gaap_InProcessResearchAndDevelopmentMember_F22EFCF9AEC56BA7F2A818A8EEA43366" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_8BD00A61ED5AEFA8961618A8EEA4B16A" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_94583135692978B3778718A8EEA36ABC" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_8BD00A61ED5AEFA8961618A8EEA4B16A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_0F608ED9932B2232387F18A8EEA4DB7D" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_8BD00A61ED5AEFA8961618A8EEA4B16A" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_0F608ED9932B2232387F18A8EEA4DB7D" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TEIBiosciencesIncandTEIMedicalInc.Member" xlink:label="loc_iart_TEIBiosciencesIncandTEIMedicalInc.Member_DF5C3080CEADA671B08318A8EEA4D3D0" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_0F608ED9932B2232387F18A8EEA4DB7D" xlink:to="loc_iart_TEIBiosciencesIncandTEIMedicalInc.Member_DF5C3080CEADA671B08318A8EEA4D3D0" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_MetasurgMember" xlink:label="loc_iart_MetasurgMember_F5F5E1E6D6F8F1997A6918A8EEA42BD2" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_0F608ED9932B2232387F18A8EEA4DB7D" xlink:to="loc_iart_MetasurgMember_F5F5E1E6D6F8F1997A6918A8EEA42BD2" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_MedtronicMicroFranceMember" xlink:label="loc_iart_MedtronicMicroFranceMember_236208B0F5780E4A7FDD18A8EEA44B45" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_0F608ED9932B2232387F18A8EEA4DB7D" xlink:to="loc_iart_MedtronicMicroFranceMember_236208B0F5780E4A7FDD18A8EEA44B45" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_ConfluentSurgicalInc.Member" xlink:label="loc_iart_ConfluentSurgicalInc.Member_318EC93C1E90AE227C0418A8EEA49EB6" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_0F608ED9932B2232387F18A8EEA4DB7D" xlink:to="loc_iart_ConfluentSurgicalInc.Member_318EC93C1E90AE227C0418A8EEA49EB6" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TarsusMedicalIncMember" xlink:label="loc_iart_TarsusMedicalIncMember_C4E0BC065816BAB9C13418A8EEA4E341" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_0F608ED9932B2232387F18A8EEA4DB7D" xlink:to="loc_iart_TarsusMedicalIncMember_C4E0BC065816BAB9C13418A8EEA4E341" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TekmedMember" xlink:label="loc_iart_TekmedMember_0112D2DC5554F109E26B18A8EEA4B229" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_0F608ED9932B2232387F18A8EEA4DB7D" xlink:to="loc_iart_TekmedMember_0112D2DC5554F109E26B18A8EEA4B229" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SaltoandFuturaMember" xlink:label="loc_iart_SaltoandFuturaMember_BB3DE9688889133500F918A8EEA48971" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_0F608ED9932B2232387F18A8EEA4DB7D" xlink:to="loc_iart_SaltoandFuturaMember_BB3DE9688889133500F918A8EEA48971" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_F3B607742B59DD04148618A8EEA443EF" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_94583135692978B3778718A8EEA36ABC" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_F3B607742B59DD04148618A8EEA443EF" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_9290583DCF589CA6AB1118A8EEA5026E" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_F3B607742B59DD04148618A8EEA443EF" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_9290583DCF589CA6AB1118A8EEA5026E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DevelopedTechnologyRightsMember" xlink:label="loc_us-gaap_DevelopedTechnologyRightsMember_57FA6E86D36902806DE118A8EEA5908D" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_9290583DCF589CA6AB1118A8EEA5026E" xlink:to="loc_us-gaap_DevelopedTechnologyRightsMember_57FA6E86D36902806DE118A8EEA5908D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ContractualRightsMember" xlink:label="loc_us-gaap_ContractualRightsMember_A0DC878EF2E550C7AC8118A8EEA5170A" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_9290583DCF589CA6AB1118A8EEA5026E" xlink:to="loc_us-gaap_ContractualRightsMember_A0DC878EF2E550C7AC8118A8EEA5170A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_TechnologyBasedIntangibleAssetsMember" xlink:label="loc_us-gaap_TechnologyBasedIntangibleAssetsMember_917DB3603F6ADE8D9FE818A8EEA53D5E" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_9290583DCF589CA6AB1118A8EEA5026E" xlink:to="loc_us-gaap_TechnologyBasedIntangibleAssetsMember_917DB3603F6ADE8D9FE818A8EEA53D5E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_TradeNamesMember" xlink:label="loc_us-gaap_TradeNamesMember_4EBEC56BE8343FFD6FC718A8EEA553FE" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_9290583DCF589CA6AB1118A8EEA5026E" xlink:to="loc_us-gaap_TradeNamesMember_4EBEC56BE8343FFD6FC718A8EEA553FE" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CustomerRelationshipsMember" xlink:label="loc_us-gaap_CustomerRelationshipsMember_41334C4D39DA9254D9EF18A8EEA589F8" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_9290583DCF589CA6AB1118A8EEA5026E" xlink:to="loc_us-gaap_CustomerRelationshipsMember_41334C4D39DA9254D9EF18A8EEA589F8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherIntangibleAssetsMember" xlink:label="loc_us-gaap_OtherIntangibleAssetsMember_16B6B6C9C647EAF85AD718A8EEA5F701" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_9290583DCF589CA6AB1118A8EEA5026E" xlink:to="loc_us-gaap_OtherIntangibleAssetsMember_16B6B6C9C647EAF85AD718A8EEA5F701" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_IntegraSupplierContractMember" xlink:label="loc_iart_IntegraSupplierContractMember_14A76B244775CD939C9E18A8EEA5486C" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_9290583DCF589CA6AB1118A8EEA5026E" xlink:to="loc_iart_IntegraSupplierContractMember_14A76B244775CD939C9E18A8EEA5486C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LeaseholdsAndLeaseholdImprovementsMember" xlink:label="loc_us-gaap_LeaseholdsAndLeaseholdImprovementsMember_3B9C442354F3B92F43D418A8EEA50723" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_9290583DCF589CA6AB1118A8EEA5026E" xlink:to="loc_us-gaap_LeaseholdsAndLeaseholdImprovementsMember_3B9C442354F3B92F43D418A8EEA50723" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_AnkleProductFamilyMember" xlink:label="loc_iart_AnkleProductFamilyMember_62E37E2C41E108BFED6C18A8EEA58F05" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_9290583DCF589CA6AB1118A8EEA5026E" xlink:to="loc_iart_AnkleProductFamilyMember_62E37E2C41E108BFED6C18A8EEA58F05" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_ToeProductFamilyMember" xlink:label="loc_iart_ToeProductFamilyMember_22250047A7981914755C18A8EEA5DE84" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_9290583DCF589CA6AB1118A8EEA5026E" xlink:to="loc_iart_ToeProductFamilyMember_22250047A7981914755C18A8EEA5DE84" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_94583135692978B3778718A8EEA36ABC" xlink:to="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesGross" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesGross_B65DA3D35ECD92C2052618A8EEA5254E" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesGross_B65DA3D35ECD92C2052618A8EEA5254E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_18DB82C74B478C3510EF18A8EEA5DD11" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_18DB82C74B478C3510EF18A8EEA5DD11" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsReceivables" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsReceivables_ECA6D83FED3DB49E394F18A8EEA5FA2F" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsReceivables_ECA6D83FED3DB49E394F18A8EEA5FA2F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedInventory" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedInventory_BA56A9EC4D73E5C6F37418A8EEA50C91" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedInventory_BA56A9EC4D73E5C6F37418A8EEA50C91" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedPropertyPlantAndEquipment" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedPropertyPlantAndEquipment_0E71F9C3B68D50EA71B818A8EEA5921D" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedPropertyPlantAndEquipment_0E71F9C3B68D50EA71B818A8EEA5921D" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedIncomeTaxReceivable" xlink:label="loc_iart_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedIncomeTaxReceivable_5E9D4FABE2CFDCC310C218A8EEA64F13" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_iart_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedIncomeTaxReceivable_5E9D4FABE2CFDCC310C218A8EEA64F13" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsOther" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsOther_F758959FA9369B88CDD218A8EEA61CD1" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsOther_F758959FA9369B88CDD218A8EEA61CD1" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibles" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibles_4EFEE7BC4AAD14FB82C818A8EEA6BFFD" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibles_4EFEE7BC4AAD14FB82C818A8EEA6BFFD" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_AACC58CE6A8D501EC75C18A8EEA66080" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_us-gaap_Goodwill_AACC58CE6A8D501EC75C18A8EEA66080" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets_423E6C004719B77A50D718A8EEA6D3B0" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets_423E6C004719B77A50D718A8EEA6D3B0" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedAccruedExpensesandOtherLiabilities" xlink:label="loc_iart_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedAccruedExpensesandOtherLiabilities_09AB1EE9AC44CD167EF418A8EEA6505B" xlink:type="locator" />
    <presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_iart_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedAccruedExpensesandOtherLiabilities_09AB1EE9AC44CD167EF418A8EEA6505B" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedDeferredtaxliabilities" xlink:label="loc_iart_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedDeferredtaxliabilities_F6F024D2025BC7A2585718A8EEA632CA" xlink:type="locator" />
    <presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_iart_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedDeferredtaxliabilities_F6F024D2025BC7A2585718A8EEA632CA" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNoncurrentLiabilitiesOther" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNoncurrentLiabilitiesOther_E83D36D660D5DB10DE7118A8EEA63A6C" xlink:type="locator" />
    <presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNoncurrentLiabilitiesOther_E83D36D660D5DB10DE7118A8EEA63A6C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsPrepaidExpenseAndOtherAssets" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsPrepaidExpenseAndOtherAssets_85BDAC8482AC58D8B17F18A8EEA6FC1D" xlink:type="locator" />
    <presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsPrepaidExpenseAndOtherAssets_85BDAC8482AC58D8B17F18A8EEA6FC1D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIndefiniteLivedIntangibleAssets" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIndefiniteLivedIntangibleAssets_CFA47593B359A0E9C81D18A8EEA6BBFC" xlink:type="locator" />
    <presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIndefiniteLivedIntangibleAssets_CFA47593B359A0E9C81D18A8EEA6BBFC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther_3DD57FDA84510165BC7D18A8EEA6CED7" xlink:type="locator" />
    <presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOther_3DD57FDA84510165BC7D18A8EEA6CED7" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedContingentLiability" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedContingentLiability_231792BEDBA5F78A2B1018A8EEA6DCC4" xlink:type="locator" />
    <presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedContingentLiability_231792BEDBA5F78A2B1018A8EEA6DCC4" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilitiesNoncurrent" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilitiesNoncurrent_F1047BBFA3C5F45D751818A8EEA6F4F8" xlink:type="locator" />
    <presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilitiesNoncurrent_F1047BBFA3C5F45D751818A8EEA6F4F8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife" xlink:label="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife_140491109855745A9AE018A8EEA73758" xlink:type="locator" />
    <presentationArc order="19" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife_140491109855745A9AE018A8EEA73758" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssetsNoncurrent" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssetsNoncurrent_179C30291AF6996B3F7318A8EEA72AD7" xlink:type="locator" />
    <presentationArc order="20" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxAssetsNoncurrent_179C30291AF6996B3F7318A8EEA72AD7" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_255401203F62AD25080E18A8EEA73422" xlink:type="locator" />
    <presentationArc order="21" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_2EE2004F24E509AA973418A8EEA5F549" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_255401203F62AD25080E18A8EEA73422" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/AcquisitionsAndProFormaResultsTables" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationsAbstract" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_7129D17C93FD2BB67031EC31F41A9935" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfRecognizedIdentifiedAssetsAcquiredAndLiabilitiesAssumedTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfRecognizedIdentifiedAssetsAcquiredAndLiabilitiesAssumedTableTextBlock_70C9F037AD0F811C71FDEC31F41A94C6" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_7129D17C93FD2BB67031EC31F41A9935" xlink:to="loc_us-gaap_ScheduleOfRecognizedIdentifiedAssetsAcquiredAndLiabilitiesAssumedTableTextBlock_70C9F037AD0F811C71FDEC31F41A94C6" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTextBlock" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTextBlock_B05AB434BE043F60B2E1EC31F41A4A9E" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_7129D17C93FD2BB67031EC31F41A9935" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTextBlock_B05AB434BE043F60B2E1EC31F41A4A9E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTextBlock" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTextBlock_5D02B67639F116E24B61EC31F41A2E11" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_7129D17C93FD2BB67031EC31F41A9935" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTextBlock_5D02B67639F116E24B61EC31F41A2E11" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessAcquisitionProFormaInformationTextBlock" xlink:label="loc_us-gaap_BusinessAcquisitionProFormaInformationTextBlock_071958E65DC747CB6966EC31F41A979B" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_7129D17C93FD2BB67031EC31F41A9935" xlink:to="loc_us-gaap_BusinessAcquisitionProFormaInformationTextBlock_071958E65DC747CB6966EC31F41A979B" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/Business" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_97C648672F3F5634C5CE55ED5A5B5063" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessDescriptionAndBasisOfPresentationTextBlock" xlink:label="loc_us-gaap_BusinessDescriptionAndBasisOfPresentationTextBlock_40082AAB570A2EC8FB6755ED5A5CFC58" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_97C648672F3F5634C5CE55ED5A5B5063" xlink:to="loc_us-gaap_BusinessDescriptionAndBasisOfPresentationTextBlock_40082AAB570A2EC8FB6755ED5A5CFC58" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/CommitmentsAndContingencies" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_860F2D5B59432A7A8BB955ED58337795" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureTextBlock" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_A5CF3A7EA0EB0A3B20BD55ED58337D33" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_860F2D5B59432A7A8BB955ED58337795" xlink:to="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_A5CF3A7EA0EB0A3B20BD55ED58337D33" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/CommitmentsAndContingenciesDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_FBA1787BDB6F85B1630756ADEACCE62C" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LossContingenciesTable" xlink:label="loc_us-gaap_LossContingenciesTable_13BD9204135EC7C78B0956ADEACC5658" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_FBA1787BDB6F85B1630756ADEACCE62C" xlink:to="loc_us-gaap_LossContingenciesTable_13BD9204135EC7C78B0956ADEACC5658" xlink:type="arc" />
    <loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_LegalEntityAxis" xlink:label="loc_dei_LegalEntityAxis_48FB6981FBE87B25F2D756ADEACCD9A1" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_13BD9204135EC7C78B0956ADEACC5658" xlink:to="loc_dei_LegalEntityAxis_48FB6981FBE87B25F2D756ADEACCD9A1" xlink:type="arc" />
    <loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityDomain" xlink:label="loc_dei_EntityDomain_F89655D6A0A34FDB594B56ADEACCCCE2" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_LegalEntityAxis_48FB6981FBE87B25F2D756ADEACCD9A1" xlink:to="loc_dei_EntityDomain_F89655D6A0A34FDB594B56ADEACCCCE2" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_ThirdPartyInsurerMember" xlink:label="loc_iart_ThirdPartyInsurerMember_BAF9B3C245B3E201249156ADEACCACA9" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityDomain_F89655D6A0A34FDB594B56ADEACCCCE2" xlink:to="loc_iart_ThirdPartyInsurerMember_BAF9B3C245B3E201249156ADEACCACA9" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StatementScenarioAxis" xlink:label="loc_us-gaap_StatementScenarioAxis_099397BBA629ACD80A5D56ADEACC4B21" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_13BD9204135EC7C78B0956ADEACC5658" xlink:to="loc_us-gaap_StatementScenarioAxis_099397BBA629ACD80A5D56ADEACC4B21" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScenarioUnspecifiedDomain" xlink:label="loc_us-gaap_ScenarioUnspecifiedDomain_AD2D87CF125B409177FE56ADEACC3361" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementScenarioAxis_099397BBA629ACD80A5D56ADEACC4B21" xlink:to="loc_us-gaap_ScenarioUnspecifiedDomain_AD2D87CF125B409177FE56ADEACC3361" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_IndemnificationPeriodOneMember" xlink:label="loc_iart_IndemnificationPeriodOneMember_3D2E9267EC1C594EEAB856ADEACCFC16" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScenarioUnspecifiedDomain_AD2D87CF125B409177FE56ADEACC3361" xlink:to="loc_iart_IndemnificationPeriodOneMember_3D2E9267EC1C594EEAB856ADEACCFC16" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_IndemnificationPeriodTwoMember" xlink:label="loc_iart_IndemnificationPeriodTwoMember_050D0CD7DD52D2D4EF0A56ADEACC8810" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScenarioUnspecifiedDomain_AD2D87CF125B409177FE56ADEACC3361" xlink:to="loc_iart_IndemnificationPeriodTwoMember_050D0CD7DD52D2D4EF0A56ADEACC8810" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_646DF26EE62B96E211C756ADEACCBE3D" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_13BD9204135EC7C78B0956ADEACC5658" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_646DF26EE62B96E211C756ADEACCBE3D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_6817B86F4EB184818A6656ADEACC62CC" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_646DF26EE62B96E211C756ADEACCBE3D" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_6817B86F4EB184818A6656ADEACC62CC" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TEIBiosciencesIncandTEIMedicalInc.Member" xlink:label="loc_iart_TEIBiosciencesIncandTEIMedicalInc.Member_FE05B3382A9CE328065D56ADEACD0F80" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_6817B86F4EB184818A6656ADEACC62CC" xlink:to="loc_iart_TEIBiosciencesIncandTEIMedicalInc.Member_FE05B3382A9CE328065D56ADEACD0F80" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LossContingenciesLineItems" xlink:label="loc_us-gaap_LossContingenciesLineItems_AA6C82AD9BBAD80F9C0956ADEACD40AE" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_13BD9204135EC7C78B0956ADEACC5658" xlink:to="loc_us-gaap_LossContingenciesLineItems_AA6C82AD9BBAD80F9C0956ADEACD40AE" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LossContingencyPendingClaimsNumber" xlink:label="loc_us-gaap_LossContingencyPendingClaimsNumber_876228CC89C3853B070C56ADEACD266A" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_AA6C82AD9BBAD80F9C0956ADEACD40AE" xlink:to="loc_us-gaap_LossContingencyPendingClaimsNumber_876228CC89C3853B070C56ADEACD266A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationIndemnificationAssetsAmountAsOfAcquisitionDate" xlink:label="loc_us-gaap_BusinessCombinationIndemnificationAssetsAmountAsOfAcquisitionDate_6495A736A6EA06985CEB56ADEACD1665" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_AA6C82AD9BBAD80F9C0956ADEACD40AE" xlink:to="loc_us-gaap_BusinessCombinationIndemnificationAssetsAmountAsOfAcquisitionDate_6495A736A6EA06985CEB56ADEACD1665" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationIndemnificationAssetsRangeOfOutcomesValueLow" xlink:label="loc_us-gaap_BusinessCombinationIndemnificationAssetsRangeOfOutcomesValueLow_45E2500C7FD366C3C25C56ADEACDA709" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_AA6C82AD9BBAD80F9C0956ADEACD40AE" xlink:to="loc_us-gaap_BusinessCombinationIndemnificationAssetsRangeOfOutcomesValueLow_45E2500C7FD366C3C25C56ADEACDA709" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationIndemnificationAssetsRangeOfOutcomesValueHigh" xlink:label="loc_us-gaap_BusinessCombinationIndemnificationAssetsRangeOfOutcomesValueHigh_A1E65A42F0B61C5BAAC956ADEACD86E0" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_AA6C82AD9BBAD80F9C0956ADEACD40AE" xlink:to="loc_us-gaap_BusinessCombinationIndemnificationAssetsRangeOfOutcomesValueHigh_A1E65A42F0B61C5BAAC956ADEACD86E0" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_BusinessCombinationIndemnificationAssetsPeriodofIndemnification" xlink:label="loc_iart_BusinessCombinationIndemnificationAssetsPeriodofIndemnification_0CC819A562E4C7ED107456ADEACD9DE5" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_AA6C82AD9BBAD80F9C0956ADEACD40AE" xlink:to="loc_iart_BusinessCombinationIndemnificationAssetsPeriodofIndemnification_0CC819A562E4C7ED107456ADEACD9DE5" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/ConsolidatedBalanceSheets" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_4649B028E0002D0592DDEB95EB24C204" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="loc_us-gaap_AssetsAbstract_898E67CEAC71BD6DDCE9EB95EB247214" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_4649B028E0002D0592DDEB95EB24C204" xlink:to="loc_us-gaap_AssetsAbstract_898E67CEAC71BD6DDCE9EB95EB247214" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AssetsCurrentAbstract" xlink:label="loc_us-gaap_AssetsCurrentAbstract_C463B67FC6F24D418594EB95EB2489EE" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_898E67CEAC71BD6DDCE9EB95EB247214" xlink:to="loc_us-gaap_AssetsCurrentAbstract_C463B67FC6F24D418594EB95EB2489EE" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_626E029B92FD7AB26785EB95EB24481F" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_C463B67FC6F24D418594EB95EB2489EE" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_626E029B92FD7AB26785EB95EB24481F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue_D7719DAF74B533372BC0EB95EB252E69" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_C463B67FC6F24D418594EB95EB2489EE" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue_D7719DAF74B533372BC0EB95EB252E69" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccountsReceivableNetCurrent" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_F6F9D4D5B102294BF3BDEB95EB2545AA" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_C463B67FC6F24D418594EB95EB2489EE" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_F6F9D4D5B102294BF3BDEB95EB2545AA" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InventoryNet" xlink:label="loc_us-gaap_InventoryNet_A8AE9FCFA07CB3AAF1FBEB95EB257050" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_C463B67FC6F24D418594EB95EB2489EE" xlink:to="loc_us-gaap_InventoryNet_A8AE9FCFA07CB3AAF1FBEB95EB257050" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxAssetsNetCurrent" xlink:label="loc_us-gaap_DeferredTaxAssetsNetCurrent_266501C58F5E49A94225EB95EB25D54F" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_C463B67FC6F24D418594EB95EB2489EE" xlink:to="loc_us-gaap_DeferredTaxAssetsNetCurrent_266501C58F5E49A94225EB95EB25D54F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_18D53A89FE3486693615EB95EB25B5DC" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_C463B67FC6F24D418594EB95EB2489EE" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_18D53A89FE3486693615EB95EB25B5DC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrent" xlink:label="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrent_EAED328ADDB968BAC940EB95EB2592DE" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_C463B67FC6F24D418594EB95EB2489EE" xlink:to="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrent_EAED328ADDB968BAC940EB95EB2592DE" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AssetsCurrent" xlink:label="loc_us-gaap_AssetsCurrent_F4572E34C1B5C929D980EB95EB25CB16" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_C463B67FC6F24D418594EB95EB2489EE" xlink:to="loc_us-gaap_AssetsCurrent_F4572E34C1B5C929D980EB95EB25CB16" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_7EF087126C8445753314EB95EB259A00" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_C463B67FC6F24D418594EB95EB2489EE" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_7EF087126C8445753314EB95EB259A00" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_653814A2745D20C43EE0EB95EB257E98" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_C463B67FC6F24D418594EB95EB2489EE" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_653814A2745D20C43EE0EB95EB257E98" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_50226176F4469079C9B4EB95EB257CAA" xlink:type="locator" />
    <presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_C463B67FC6F24D418594EB95EB2489EE" xlink:to="loc_us-gaap_Goodwill_50226176F4469079C9B4EB95EB257CAA" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxAssetsNetNoncurrent" xlink:label="loc_us-gaap_DeferredTaxAssetsNetNoncurrent_3FC799B177721F9E86CDEB95EB251975" xlink:type="locator" />
    <presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_C463B67FC6F24D418594EB95EB2489EE" xlink:to="loc_us-gaap_DeferredTaxAssetsNetNoncurrent_3FC799B177721F9E86CDEB95EB251975" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherAssetsNoncurrent" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_0D66B168215E5AA5FE69EB95EB265905" xlink:type="locator" />
    <presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_C463B67FC6F24D418594EB95EB2489EE" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_0D66B168215E5AA5FE69EB95EB265905" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationAssetsNoncurrent" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationAssetsNoncurrent_658550213958987C1E94EB95EB2665CD" xlink:type="locator" />
    <presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_C463B67FC6F24D418594EB95EB2489EE" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationAssetsNoncurrent_658550213958987C1E94EB95EB2665CD" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_Assets" xlink:label="loc_us-gaap_Assets_E174A97A6E47FA8C895FEB95EB26F0EC" xlink:type="locator" />
    <presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_C463B67FC6F24D418594EB95EB2489EE" xlink:to="loc_us-gaap_Assets_E174A97A6E47FA8C895FEB95EB26F0EC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_22B389547C105B77920AEB95EB26A73F" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_4649B028E0002D0592DDEB95EB24C204" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_22B389547C105B77920AEB95EB26A73F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract" xlink:label="loc_us-gaap_LiabilitiesCurrentAbstract_94147A51ED1D5A3F6309EB95EB26E084" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_22B389547C105B77920AEB95EB26A73F" xlink:to="loc_us-gaap_LiabilitiesCurrentAbstract_94147A51ED1D5A3F6309EB95EB26E084" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SecuredDebtCurrent" xlink:label="loc_us-gaap_SecuredDebtCurrent_ED6BF9293210C9E9DAC5EB95EB260BF0" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_94147A51ED1D5A3F6309EB95EB26E084" xlink:to="loc_us-gaap_SecuredDebtCurrent_ED6BF9293210C9E9DAC5EB95EB260BF0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccountsPayableTradeCurrent" xlink:label="loc_us-gaap_AccountsPayableTradeCurrent_74B158F764759455F1CBEB95EB26D7C7" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_94147A51ED1D5A3F6309EB95EB26E084" xlink:to="loc_us-gaap_AccountsPayableTradeCurrent_74B158F764759455F1CBEB95EB26D7C7" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredRevenueCurrent" xlink:label="loc_us-gaap_DeferredRevenueCurrent_65C5A24BBFD1CD669D9AEB95EB26C2D3" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_94147A51ED1D5A3F6309EB95EB26E084" xlink:to="loc_us-gaap_DeferredRevenueCurrent_65C5A24BBFD1CD669D9AEB95EB26C2D3" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_B7CC93F8EA8A102354D1EB95EB267C5E" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_94147A51ED1D5A3F6309EB95EB26E084" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_B7CC93F8EA8A102354D1EB95EB267C5E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_9021AF2240775650B097EB95EB268122" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_94147A51ED1D5A3F6309EB95EB26E084" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_9021AF2240775650B097EB95EB268122" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrent" xlink:label="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrent_781FB7D08A4CFAC8990FEB95EB26E0E0" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_94147A51ED1D5A3F6309EB95EB26E084" xlink:to="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrent_781FB7D08A4CFAC8990FEB95EB26E0E0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LiabilitiesCurrent" xlink:label="loc_us-gaap_LiabilitiesCurrent_876BF71E16269B4B96AAEB95EB267D57" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_94147A51ED1D5A3F6309EB95EB26E084" xlink:to="loc_us-gaap_LiabilitiesCurrent_876BF71E16269B4B96AAEB95EB267D57" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SecuredLongTermDebt" xlink:label="loc_us-gaap_SecuredLongTermDebt_00B645509F8AA7D0C663EB95EB26C105" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_94147A51ED1D5A3F6309EB95EB26E084" xlink:to="loc_us-gaap_SecuredLongTermDebt_00B645509F8AA7D0C663EB95EB26C105" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ConvertibleDebtNoncurrent" xlink:label="loc_us-gaap_ConvertibleDebtNoncurrent_DD7EB059B8D098AE04CBEB95EB26F02F" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_94147A51ED1D5A3F6309EB95EB26E084" xlink:to="loc_us-gaap_ConvertibleDebtNoncurrent_DD7EB059B8D098AE04CBEB95EB26F02F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxLiabilitiesGrossNoncurrent" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesGrossNoncurrent_843295514D4DA185B9DFEB95EB27BCA6" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_94147A51ED1D5A3F6309EB95EB26E084" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesGrossNoncurrent_843295514D4DA185B9DFEB95EB27BCA6" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherLiabilitiesNoncurrent" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_D397531FF6C20B26D7C7EB95EB274D95" xlink:type="locator" />
    <presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_94147A51ED1D5A3F6309EB95EB26E084" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_D397531FF6C20B26D7C7EB95EB274D95" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrent" xlink:label="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrent_E83BF68B4F2F2EE9FAD8EB95EB272574" xlink:type="locator" />
    <presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_94147A51ED1D5A3F6309EB95EB26E084" xlink:to="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrent_E83BF68B4F2F2EE9FAD8EB95EB272574" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_Liabilities" xlink:label="loc_us-gaap_Liabilities_56B573E76329ABC4CA4EEB95EB27A6C0" xlink:type="locator" />
    <presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_94147A51ED1D5A3F6309EB95EB26E084" xlink:to="loc_us-gaap_Liabilities_56B573E76329ABC4CA4EEB95EB27A6C0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CommitmentsAndContingencies" xlink:label="loc_us-gaap_CommitmentsAndContingencies_00406BC8271939CA6CB3EB95EB27065E" xlink:type="locator" />
    <presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_94147A51ED1D5A3F6309EB95EB26E084" xlink:to="loc_us-gaap_CommitmentsAndContingencies_00406BC8271939CA6CB3EB95EB27065E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="loc_us-gaap_StockholdersEquityAbstract_E9F10F594D5BD53A8127EB95EB276C2D" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_22B389547C105B77920AEB95EB26A73F" xlink:to="loc_us-gaap_StockholdersEquityAbstract_E9F10F594D5BD53A8127EB95EB276C2D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PreferredStockValue" xlink:label="loc_us-gaap_PreferredStockValue_2918054E47AF0C72139DEB95EB27292D" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_E9F10F594D5BD53A8127EB95EB276C2D" xlink:to="loc_us-gaap_PreferredStockValue_2918054E47AF0C72139DEB95EB27292D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CommonStockValue" xlink:label="loc_us-gaap_CommonStockValue_AD435D454E5AE651DC17EB95EB272A89" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_E9F10F594D5BD53A8127EB95EB276C2D" xlink:to="loc_us-gaap_CommonStockValue_AD435D454E5AE651DC17EB95EB272A89" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AdditionalPaidInCapitalCommonStock" xlink:label="loc_us-gaap_AdditionalPaidInCapitalCommonStock_F40D2F913A0CF4B249C9EB95EB278A62" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_E9F10F594D5BD53A8127EB95EB276C2D" xlink:to="loc_us-gaap_AdditionalPaidInCapitalCommonStock_F40D2F913A0CF4B249C9EB95EB278A62" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_TreasuryStockValue" xlink:label="loc_us-gaap_TreasuryStockValue_979B8C0D86E17C52F5C5EB95EB271305" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_E9F10F594D5BD53A8127EB95EB276C2D" xlink:to="loc_us-gaap_TreasuryStockValue_979B8C0D86E17C52F5C5EB95EB271305" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_C6A561F11FD49B386C3CEB95EB2850DE" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_E9F10F594D5BD53A8127EB95EB276C2D" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_C6A561F11FD49B386C3CEB95EB2850DE" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_12D8F2248B2530761B29EB95EB284497" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_E9F10F594D5BD53A8127EB95EB276C2D" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_12D8F2248B2530761B29EB95EB284497" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_3B5494AFBD859F73B723EB95EB288A4A" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_E9F10F594D5BD53A8127EB95EB276C2D" xlink:to="loc_us-gaap_StockholdersEquity_3B5494AFBD859F73B723EB95EB288A4A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_12C07C49213D12D07A56EB95EB28ED86" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_22B389547C105B77920AEB95EB26A73F" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquity_12C07C49213D12D07A56EB95EB28ED86" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_647847640735154DC317324B94429680" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivableCurrent" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableCurrent_8201793A8F76001A84BE324B94429520" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_647847640735154DC317324B94429680" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableCurrent_8201793A8F76001A84BE324B94429520" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PreferredStockNoParValue" xlink:label="loc_us-gaap_PreferredStockNoParValue_62F54F90939BBDAACE99324B9443C8BF" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_647847640735154DC317324B94429680" xlink:to="loc_us-gaap_PreferredStockNoParValue_62F54F90939BBDAACE99324B9443C8BF" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PreferredStockSharesAuthorized" xlink:label="loc_us-gaap_PreferredStockSharesAuthorized_458AC5EA4FE695610959324B944316B6" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_647847640735154DC317324B94429680" xlink:to="loc_us-gaap_PreferredStockSharesAuthorized_458AC5EA4FE695610959324B944316B6" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PreferredStockSharesOutstanding" xlink:label="loc_us-gaap_PreferredStockSharesOutstanding_835E26C767F8549C306F324B94434024" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_647847640735154DC317324B94429680" xlink:to="loc_us-gaap_PreferredStockSharesOutstanding_835E26C767F8549C306F324B94434024" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CommonStockParOrStatedValuePerShare" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_962F00AF3FA26B34B927324B94437A58" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_647847640735154DC317324B94429680" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_962F00AF3FA26B34B927324B94437A58" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CommonStockSharesAuthorized" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_D0F56383983CA7832FC4324B9443E9EA" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_647847640735154DC317324B94429680" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_D0F56383983CA7832FC4324B9443E9EA" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CommonStockSharesIssued" xlink:label="loc_us-gaap_CommonStockSharesIssued_5F3E7B65389FF02DCA01324B9443D671" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_647847640735154DC317324B94429680" xlink:to="loc_us-gaap_CommonStockSharesIssued_5F3E7B65389FF02DCA01324B9443D671" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_TreasuryStockShares" xlink:label="loc_us-gaap_TreasuryStockShares_8611D57BE6C35B0D1285324B9443826A" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_647847640735154DC317324B94429680" xlink:to="loc_us-gaap_TreasuryStockShares_8611D57BE6C35B0D1285324B9443826A" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/ConsolidatedStatementsOfCashFlows" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract_6E33891FB14F2F840B3619292CAAE409" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_5C1008ADD536C3CF8C9719292CAAE96E" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_6E33891FB14F2F840B3619292CAAE409" xlink:to="loc_us-gaap_NetIncomeLoss_5C1008ADD536C3CF8C9719292CAAE96E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_96EDB97CF6720649527C19292CAA3974" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_6E33891FB14F2F840B3619292CAAE409" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_96EDB97CF6720649527C19292CAA3974" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_31142B96746F48B7C3CF19292CAA0C55" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_96EDB97CF6720649527C19292CAA3974" xlink:to="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_31142B96746F48B7C3CF19292CAA0C55" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_C8B850A394CC08DD25B919292CAA080E" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_31142B96746F48B7C3CF19292CAA0C55" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_C8B850A394CC08DD25B919292CAA080E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DepreciationDepletionAndAmortization" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_6A18DD0AE238CCA9738419292CAAC0BA" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_31142B96746F48B7C3CF19292CAA0C55" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_6A18DD0AE238CCA9738419292CAAC0BA" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AssetImpairmentCharges" xlink:label="loc_us-gaap_AssetImpairmentCharges_6857B4F8FD6190A6718E19292CAA1BA9" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_31142B96746F48B7C3CF19292CAA0C55" xlink:to="loc_us-gaap_AssetImpairmentCharges_6857B4F8FD6190A6718E19292CAA1BA9" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_A1C205CE1754712A24EB19292CAB9B65" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_31142B96746F48B7C3CF19292CAA0C55" xlink:to="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_A1C205CE1754712A24EB19292CAB9B65" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities" xlink:label="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities_81BE5C2AC07D09E451E319292CABA74C" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_31142B96746F48B7C3CF19292CAA0C55" xlink:to="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities_81BE5C2AC07D09E451E319292CABA74C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensation" xlink:label="loc_us-gaap_ShareBasedCompensation_DD858E8757566F1149C019292CAB02B9" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_31142B96746F48B7C3CF19292CAA0C55" xlink:to="loc_us-gaap_ShareBasedCompensation_DD858E8757566F1149C019292CAB02B9" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AmortizationOfFinancingCosts" xlink:label="loc_us-gaap_AmortizationOfFinancingCosts_CF106C17DF35EF59256219292CAB7A83" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_31142B96746F48B7C3CF19292CAA0C55" xlink:to="loc_us-gaap_AmortizationOfFinancingCosts_CF106C17DF35EF59256219292CAB7A83" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccretionExpense" xlink:label="loc_us-gaap_AccretionExpense_D9D9D51FD89F4266A79D19292CABE1F8" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_31142B96746F48B7C3CF19292CAA0C55" xlink:to="loc_us-gaap_AccretionExpense_D9D9D51FD89F4266A79D19292CABE1F8" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_PaymentOfAccretedInterestCashFlow" xlink:label="loc_iart_PaymentOfAccretedInterestCashFlow_BF74410828A992EEAC3B19292CAB869E" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_31142B96746F48B7C3CF19292CAA0C55" xlink:to="loc_iart_PaymentOfAccretedInterestCashFlow_BF74410828A992EEAC3B19292CAB869E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_GainLossOnDispositionOfAssets" xlink:label="loc_us-gaap_GainLossOnDispositionOfAssets_CF4BB25D7E96E809955419292CB0861A" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_31142B96746F48B7C3CF19292CAA0C55" xlink:to="loc_us-gaap_GainLossOnDispositionOfAssets_CF4BB25D7E96E809955419292CB0861A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ExcessTaxBenefitFromShareBasedCompensationOperatingActivities" xlink:label="loc_us-gaap_ExcessTaxBenefitFromShareBasedCompensationOperatingActivities_190CD34C6DBDD8DFADF619292CB07EE7" xlink:type="locator" />
    <presentationArc order="11" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_31142B96746F48B7C3CF19292CAA0C55" xlink:to="loc_us-gaap_ExcessTaxBenefitFromShareBasedCompensationOperatingActivities_190CD34C6DBDD8DFADF619292CB07EE7" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherNoncashIncomeExpense" xlink:label="loc_us-gaap_OtherNoncashIncomeExpense_BB7BE8594EEE5F2FE7DF19292CB0F13A" xlink:type="locator" />
    <presentationArc order="12" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_31142B96746F48B7C3CF19292CAA0C55" xlink:to="loc_us-gaap_OtherNoncashIncomeExpense_BB7BE8594EEE5F2FE7DF19292CB0F13A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessCombinationBargainPurchaseGainRecognizedAmount" xlink:label="loc_us-gaap_BusinessCombinationBargainPurchaseGainRecognizedAmount_12D20AB0D0D2ADD4386019292CB0FEE8" xlink:type="locator" />
    <presentationArc order="13" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_31142B96746F48B7C3CF19292CAA0C55" xlink:to="loc_us-gaap_BusinessCombinationBargainPurchaseGainRecognizedAmount_12D20AB0D0D2ADD4386019292CB0FEE8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_9F7BD2226D98F65ACF0C19292CB087E6" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_96EDB97CF6720649527C19292CAA3974" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_9F7BD2226D98F65ACF0C19292CB087E6" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_BE656E694277AFC82ECC19292CB04EDD" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_9F7BD2226D98F65ACF0C19292CB087E6" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_BE656E694277AFC82ECC19292CB04EDD" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncreaseDecreaseInInventories" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories_2452F3049BD09C65454E19292CB067ED" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_9F7BD2226D98F65ACF0C19292CB087E6" xlink:to="loc_us-gaap_IncreaseDecreaseInInventories_2452F3049BD09C65454E19292CB067ED" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_6091D62877677D08C79C19292CB1216C" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_9F7BD2226D98F65ACF0C19292CB087E6" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_6091D62877677D08C79C19292CB1216C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncreaseDecreaseInOtherOperatingAssets" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_DB01EF51A2F2EC0E00AA19292CB17741" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_9F7BD2226D98F65ACF0C19292CB087E6" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_DB01EF51A2F2EC0E00AA19292CB17741" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_B8CF33A090D58C30731919292CB1B58C" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_9F7BD2226D98F65ACF0C19292CB087E6" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_B8CF33A090D58C30731919292CB1B58C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncreaseDecreaseInDeferredRevenue" xlink:label="loc_us-gaap_IncreaseDecreaseInDeferredRevenue_167D5C0AA2A7FE50D97219292CB12098" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_9F7BD2226D98F65ACF0C19292CB087E6" xlink:to="loc_us-gaap_IncreaseDecreaseInDeferredRevenue_167D5C0AA2A7FE50D97219292CB12098" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities_9DCD2826EC195CA32B6619292CB19840" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_9F7BD2226D98F65ACF0C19292CB087E6" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities_9DCD2826EC195CA32B6619292CB19840" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations_3ACC04D62C9D0860857319292CB171F2" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_9F7BD2226D98F65ACF0C19292CB087E6" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations_3ACC04D62C9D0860857319292CB171F2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CashProvidedByUsedInOperatingActivitiesDiscontinuedOperations" xlink:label="loc_us-gaap_CashProvidedByUsedInOperatingActivitiesDiscontinuedOperations_4A9BEF21F67F77EF845719292CB1632B" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_9F7BD2226D98F65ACF0C19292CB087E6" xlink:to="loc_us-gaap_CashProvidedByUsedInOperatingActivitiesDiscontinuedOperations_4A9BEF21F67F77EF845719292CB1632B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_FCA744939B48967D13C219292CB15849" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_9F7BD2226D98F65ACF0C19292CB087E6" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_FCA744939B48967D13C219292CB15849" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_9B39241011F52F83BEC819292CB120F0" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_6E33891FB14F2F840B3619292CAAE409" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_9B39241011F52F83BEC819292CB120F0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncreaseDecreaseInRestrictedCash" xlink:label="loc_us-gaap_IncreaseDecreaseInRestrictedCash_BDBC984E83E0A20B14AB19292CB180A6" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_9B39241011F52F83BEC819292CB120F0" xlink:to="loc_us-gaap_IncreaseDecreaseInRestrictedCash_BDBC984E83E0A20B14AB19292CB180A6" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_97935B1408C929A296F019292CB13A6E" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_9B39241011F52F83BEC819292CB120F0" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_97935B1408C929A296F019292CB13A6E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_A14C34A25997D16A36B719292CB1F77B" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_9B39241011F52F83BEC819292CB120F0" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_A14C34A25997D16A36B719292CB1F77B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment" xlink:label="loc_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment_496F08491B901DFF9C9A19292CB106E4" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_9B39241011F52F83BEC819292CB120F0" xlink:to="loc_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment_496F08491B901DFF9C9A19292CB106E4" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PaymentsForProceedsFromOtherInvestingActivities" xlink:label="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_085C8699692E1EF92F9919292CB1B315" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_9B39241011F52F83BEC819292CB120F0" xlink:to="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_085C8699692E1EF92F9919292CB1B315" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations_33FA1565FB3E00346B8F19292CB110D1" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_9B39241011F52F83BEC819292CB120F0" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations_33FA1565FB3E00346B8F19292CB110D1" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CashProvidedByUsedInInvestingActivitiesDiscontinuedOperations" xlink:label="loc_us-gaap_CashProvidedByUsedInInvestingActivitiesDiscontinuedOperations_AA2AF918764C6A8A059519292CB1F97D" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_9B39241011F52F83BEC819292CB120F0" xlink:to="loc_us-gaap_CashProvidedByUsedInInvestingActivitiesDiscontinuedOperations_AA2AF918764C6A8A059519292CB1F97D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_ED4AB832564AEAB4F6A019292CB115EB" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_9B39241011F52F83BEC819292CB120F0" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_ED4AB832564AEAB4F6A019292CB115EB" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_855AAB4AC9E47DE4493D19292CB2F467" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_6E33891FB14F2F840B3619292CAAE409" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_855AAB4AC9E47DE4493D19292CB2F467" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ProceedsFromIssuanceOfSecuredDebt" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfSecuredDebt_F4E00BD8F4070A5FF82A19292CB288FB" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_855AAB4AC9E47DE4493D19292CB2F467" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfSecuredDebt_F4E00BD8F4070A5FF82A19292CB288FB" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RepaymentsOfSecuredDebt" xlink:label="loc_us-gaap_RepaymentsOfSecuredDebt_A167F331D1ABD425238B19292CB27070" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_855AAB4AC9E47DE4493D19292CB2F467" xlink:to="loc_us-gaap_RepaymentsOfSecuredDebt_A167F331D1ABD425238B19292CB27070" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_FFE2E4B05BCA5696711619292CB224F7" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_855AAB4AC9E47DE4493D19292CB2F467" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_FFE2E4B05BCA5696711619292CB224F7" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CashProvidedByUsedInFinancingActivitiesDiscontinuedOperations" xlink:label="loc_us-gaap_CashProvidedByUsedInFinancingActivitiesDiscontinuedOperations_D339027CB613CC9F253519292CB259AE" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_855AAB4AC9E47DE4493D19292CB2F467" xlink:to="loc_us-gaap_CashProvidedByUsedInFinancingActivitiesDiscontinuedOperations_D339027CB613CC9F253519292CB259AE" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RepaymentsOfConvertibleDebt" xlink:label="loc_us-gaap_RepaymentsOfConvertibleDebt_F2725846010337E62DC719292CB2C800" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_855AAB4AC9E47DE4493D19292CB2F467" xlink:to="loc_us-gaap_RepaymentsOfConvertibleDebt_F2725846010337E62DC719292CB2C800" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RepaymentsOfLongTermCapitalLeaseObligations" xlink:label="loc_us-gaap_RepaymentsOfLongTermCapitalLeaseObligations_4F96727A41CA6090E55919292CB2CF9C" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_855AAB4AC9E47DE4493D19292CB2F467" xlink:to="loc_us-gaap_RepaymentsOfLongTermCapitalLeaseObligations_4F96727A41CA6090E55919292CB2CF9C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PaymentsOfDebtIssuanceCosts" xlink:label="loc_us-gaap_PaymentsOfDebtIssuanceCosts_FB37F45D27F7B091FA7819292CB2D128" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_855AAB4AC9E47DE4493D19292CB2F467" xlink:to="loc_us-gaap_PaymentsOfDebtIssuanceCosts_FB37F45D27F7B091FA7819292CB2D128" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ProceedsFromStockOptionsExercised" xlink:label="loc_us-gaap_ProceedsFromStockOptionsExercised_E46A586ACAEFDB03CD8C19292CB2EECE" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_855AAB4AC9E47DE4493D19292CB2F467" xlink:to="loc_us-gaap_ProceedsFromStockOptionsExercised_E46A586ACAEFDB03CD8C19292CB2EECE" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ExcessTaxBenefitFromShareBasedCompensationFinancingActivities" xlink:label="loc_us-gaap_ExcessTaxBenefitFromShareBasedCompensationFinancingActivities_DD2880947EABE3224F0119292CB2FD19" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_855AAB4AC9E47DE4493D19292CB2F467" xlink:to="loc_us-gaap_ExcessTaxBenefitFromShareBasedCompensationFinancingActivities_DD2880947EABE3224F0119292CB2FD19" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_33673F30F8ECDC21EC4619292CB2A006" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_855AAB4AC9E47DE4493D19292CB2F467" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_33673F30F8ECDC21EC4619292CB2A006" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents_AAF53EF429535B4A5C8619292CB2EF7B" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_6E33891FB14F2F840B3619292CAAE409" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents_AAF53EF429535B4A5C8619292CB2EF7B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease" xlink:label="loc_us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease_CE6F9CE9030D0AC5CBBB19292CB21015" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_6E33891FB14F2F840B3619292CAAE409" xlink:to="loc_us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease_CE6F9CE9030D0AC5CBBB19292CB21015" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValueIncludingDiscontinuedOperations" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValueIncludingDiscontinuedOperations_94F1CC00419028B2701E19292CB213AE" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_6E33891FB14F2F840B3619292CAAE409" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValueIncludingDiscontinuedOperations_94F1CC00419028B2701E19292CB213AE" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValueIncludingDiscontinuedOperations" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValueIncludingDiscontinuedOperations_FCD20EAF2BCDE5DDCAC51931D358187A" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_6E33891FB14F2F840B3619292CAAE409" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValueIncludingDiscontinuedOperations_FCD20EAF2BCDE5DDCAC51931D358187A" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/ConsolidatedStatementsOfChangesInStockholdersEquity" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_1E6517460EDB860BF51215B8C6CA497E" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaap_StatementTable_CB6D112FD887C62FAD7C15B8C6CA945E" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_1E6517460EDB860BF51215B8C6CA497E" xlink:to="loc_us-gaap_StatementTable_CB6D112FD887C62FAD7C15B8C6CA945E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_2F8DCE9A76737FC7A13A15B8C6CA1971" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_CB6D112FD887C62FAD7C15B8C6CA945E" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_2F8DCE9A76737FC7A13A15B8C6CA1971" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_0D7CC084DBC10379CB4715B8C6CA8374" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_2F8DCE9A76737FC7A13A15B8C6CA1971" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_0D7CC084DBC10379CB4715B8C6CA8374" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SeaSpineMember" xlink:label="loc_iart_SeaSpineMember_A63C93FC47D41A048DA715B8C6CAED11" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_0D7CC084DBC10379CB4715B8C6CA8374" xlink:to="loc_iart_SeaSpineMember_A63C93FC47D41A048DA715B8C6CAED11" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_9D097F9F3E434B27ACC015B8C6CA4891" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_CB6D112FD887C62FAD7C15B8C6CA945E" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_9D097F9F3E434B27ACC015B8C6CA4891" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_CB885C33F9AFDE77371115B8C6CA7B2C" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_9D097F9F3E434B27ACC015B8C6CA4891" xlink:to="loc_us-gaap_EquityComponentDomain_CB885C33F9AFDE77371115B8C6CA7B2C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaap_CommonStockMember_57E4E6B322B1001B3AF815B8C6CAE50E" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_CB885C33F9AFDE77371115B8C6CA7B2C" xlink:to="loc_us-gaap_CommonStockMember_57E4E6B322B1001B3AF815B8C6CAE50E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_TreasuryStockMember" xlink:label="loc_us-gaap_TreasuryStockMember_1B3C584647CC9216BB9015B8C6CA427C" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_CB885C33F9AFDE77371115B8C6CA7B2C" xlink:to="loc_us-gaap_TreasuryStockMember_1B3C584647CC9216BB9015B8C6CA427C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AdditionalPaidInCapitalMember" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_DDF412534AC5EEBD741115B8C6CAD7AE" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_CB885C33F9AFDE77371115B8C6CA7B2C" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_DDF412534AC5EEBD741115B8C6CAD7AE" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_9A2CF8E7633F43ABF55D15B8C6CA9DEA" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_CB885C33F9AFDE77371115B8C6CA7B2C" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_9A2CF8E7633F43ABF55D15B8C6CA9DEA" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RetainedEarningsMember" xlink:label="loc_us-gaap_RetainedEarningsMember_FECCBA50EC515520C54615B8C6CA1B78" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_CB885C33F9AFDE77371115B8C6CA7B2C" xlink:to="loc_us-gaap_RetainedEarningsMember_FECCBA50EC515520C54615B8C6CA1B78" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaap_StatementLineItems_C431276A3E5C0073E28415B8C6CA5E1D" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_CB6D112FD887C62FAD7C15B8C6CA945E" xlink:to="loc_us-gaap_StatementLineItems_C431276A3E5C0073E28415B8C6CA5E1D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_DA1819092BB23F3B725F15B8C6CBAA53" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_C431276A3E5C0073E28415B8C6CA5E1D" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_DA1819092BB23F3B725F15B8C6CBAA53" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_A6DD3F53C79152AFC1C615B8C6CBB9CB" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_DA1819092BB23F3B725F15B8C6CBAA53" xlink:to="loc_us-gaap_StockholdersEquity_A6DD3F53C79152AFC1C615B8C6CBB9CB" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SharesIssued" xlink:label="loc_us-gaap_SharesIssued_9F4FCD62F0210276453015B8C6CB0030" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_DA1819092BB23F3B725F15B8C6CBAA53" xlink:to="loc_us-gaap_SharesIssued_9F4FCD62F0210276453015B8C6CB0030" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_TreasuryStockShares" xlink:label="loc_us-gaap_TreasuryStockShares_1E0079B614C124E0E65C15B8C6CBE68B" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedPeriodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_DA1819092BB23F3B725F15B8C6CBAA53" xlink:to="loc_us-gaap_TreasuryStockShares_1E0079B614C124E0E65C15B8C6CBE68B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_FAF34662A635EAB9667315B8C6CBBCC7" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_DA1819092BB23F3B725F15B8C6CBAA53" xlink:to="loc_us-gaap_NetIncomeLoss_FAF34662A635EAB9667315B8C6CBBCC7" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_692617886E145A8FDAE115B8C6CB9627" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_DA1819092BB23F3B725F15B8C6CBAA53" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_692617886E145A8FDAE115B8C6CB9627" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueNewIssues" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_981FFB8BE19D8EFD4EB015B8C6CB54D0" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_DA1819092BB23F3B725F15B8C6CBAA53" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_981FFB8BE19D8EFD4EB015B8C6CB54D0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockholdersEquityNoteSpinoffTransaction" xlink:label="loc_us-gaap_StockholdersEquityNoteSpinoffTransaction_B1B5E6FF7144F934875215B8C6CA4D5D" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_DA1819092BB23F3B725F15B8C6CBAA53" xlink:to="loc_us-gaap_StockholdersEquityNoteSpinoffTransaction_B1B5E6FF7144F934875215B8C6CA4D5D" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_OtherComprehensiveIncomeLossNetofTaxPortionAttributabletoParentNetofSpinoff" xlink:label="loc_iart_OtherComprehensiveIncomeLossNetofTaxPortionAttributabletoParentNetofSpinoff_626114E1CF0C12DDE00915B8C6CADF37" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_DA1819092BB23F3B725F15B8C6CBAA53" xlink:to="loc_iart_OtherComprehensiveIncomeLossNetofTaxPortionAttributabletoParentNetofSpinoff_626114E1CF0C12DDE00915B8C6CADF37" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_23E6A1D7D79EA7DC4A8F15B8C6CB9341" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_DA1819092BB23F3B725F15B8C6CBAA53" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_23E6A1D7D79EA7DC4A8F15B8C6CB9341" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueEmployeeBenefitPlan" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueEmployeeBenefitPlan_CD6AF2DE9EC2484FDCBF15B8C6CBBCFE" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_DA1819092BB23F3B725F15B8C6CBAA53" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueEmployeeBenefitPlan_CD6AF2DE9EC2484FDCBF15B8C6CBBCFE" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesEmployeeBenefitPlan" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesEmployeeBenefitPlan_4386E2A2061C6933D1C515B8C6CB8D2D" xlink:type="locator" />
    <presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_DA1819092BB23F3B725F15B8C6CBAA53" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesEmployeeBenefitPlan_4386E2A2061C6933D1C515B8C6CB8D2D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation_8CB19174BF27ADEBF43115B8C6CB280D" xlink:type="locator" />
    <presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_DA1819092BB23F3B725F15B8C6CBAA53" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation_8CB19174BF27ADEBF43115B8C6CB280D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation_83FD61624B3AB209F1B015B8C6CB12D2" xlink:type="locator" />
    <presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_DA1819092BB23F3B725F15B8C6CBAA53" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation_83FD61624B3AB209F1B015B8C6CB12D2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_TreasuryStockShares" xlink:label="loc_us-gaap_TreasuryStockShares_48E0C1C4ED22F46BE6ED15B8C6CBC05D" xlink:type="locator" />
    <presentationArc order="14" preferredLabel="http://www.xbrl.org/2009/role/negatedPeriodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_DA1819092BB23F3B725F15B8C6CBAA53" xlink:to="loc_us-gaap_TreasuryStockShares_48E0C1C4ED22F46BE6ED15B8C6CBC05D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_TreasuryStockSharesAcquired" xlink:label="loc_us-gaap_TreasuryStockSharesAcquired_7EF81A7F79C8A4EA890D15B8C6CBF1C4" xlink:type="locator" />
    <presentationArc order="15" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_DA1819092BB23F3B725F15B8C6CBAA53" xlink:to="loc_us-gaap_TreasuryStockSharesAcquired_7EF81A7F79C8A4EA890D15B8C6CBF1C4" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SharesIssued" xlink:label="loc_us-gaap_SharesIssued_9AC84ED1FC0C42C2C6F415B8C6CC0F09" xlink:type="locator" />
    <presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_DA1819092BB23F3B725F15B8C6CBAA53" xlink:to="loc_us-gaap_SharesIssued_9AC84ED1FC0C42C2C6F415B8C6CC0F09" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_B36D1A4C7079B8E2101815B8C6CC4A95" xlink:type="locator" />
    <presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_DA1819092BB23F3B725F15B8C6CBAA53" xlink:to="loc_us-gaap_StockholdersEquity_B36D1A4C7079B8E2101815B8C6CC4A95" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/ConsolidatedStatementsOfComprehensiveIncomeLoss" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract" xlink:label="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_AA92993C7835F2953A5E1F4B84CA5DC0" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_EF9D60F1D36DAC8A69371F4B84CA054D" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_AA92993C7835F2953A5E1F4B84CA5DC0" xlink:to="loc_us-gaap_NetIncomeLoss_EF9D60F1D36DAC8A69371F4B84CA054D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeTaxPortionAttributableToParentAbstract" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeTaxPortionAttributableToParentAbstract_1C1127441AF96D0B6C3D1F4B84CA2BAF" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_AA92993C7835F2953A5E1F4B84CA5DC0" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeTaxPortionAttributableToParentAbstract_1C1127441AF96D0B6C3D1F4B84CA2BAF" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentBeforeTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentBeforeTax_219503427614C6FABB2D1F4B84CA3412" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossBeforeTaxPortionAttributableToParentAbstract_1C1127441AF96D0B6C3D1F4B84CA2BAF" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentBeforeTax_219503427614C6FABB2D1F4B84CA3412" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherComprehensiveIncomeDerivativesQualifyingAsHedgesBeforeTaxPeriodIncreaseDecreaseAbstract" xlink:label="loc_us-gaap_OtherComprehensiveIncomeDerivativesQualifyingAsHedgesBeforeTaxPeriodIncreaseDecreaseAbstract_ED6E946061ABCD6FA18D1F4B84CB0C69" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossBeforeTaxPortionAttributableToParentAbstract_1C1127441AF96D0B6C3D1F4B84CA2BAF" xlink:to="loc_us-gaap_OtherComprehensiveIncomeDerivativesQualifyingAsHedgesBeforeTaxPeriodIncreaseDecreaseAbstract_ED6E946061ABCD6FA18D1F4B84CB0C69" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedGainLossOnDerivativesArisingDuringPeriodBeforeTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedGainLossOnDerivativesArisingDuringPeriodBeforeTax_D984534401B073E445451F4B84CB44A4" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeDerivativesQualifyingAsHedgesBeforeTaxPeriodIncreaseDecreaseAbstract_ED6E946061ABCD6FA18D1F4B84CB0C69" xlink:to="loc_us-gaap_OtherComprehensiveIncomeUnrealizedGainLossOnDerivativesArisingDuringPeriodBeforeTax_D984534401B073E445451F4B84CB44A4" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIOnDerivativesBeforeTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIOnDerivativesBeforeTax_71930F796139AA1BECB31F4B84CB5341" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeDerivativesQualifyingAsHedgesBeforeTaxPeriodIncreaseDecreaseAbstract_ED6E946061ABCD6FA18D1F4B84CB0C69" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIOnDerivativesBeforeTax_71930F796139AA1BECB31F4B84CB5341" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherComprehensiveIncomeDerivativesQualifyingAsHedgesBeforeTaxPortionAttributableToParent" xlink:label="loc_us-gaap_OtherComprehensiveIncomeDerivativesQualifyingAsHedgesBeforeTaxPortionAttributableToParent_B5E8AF1412EF276A17C61F4B84CB1DCD" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeDerivativesQualifyingAsHedgesBeforeTaxPeriodIncreaseDecreaseAbstract_ED6E946061ABCD6FA18D1F4B84CB0C69" xlink:to="loc_us-gaap_OtherComprehensiveIncomeDerivativesQualifyingAsHedgesBeforeTaxPortionAttributableToParent_B5E8AF1412EF276A17C61F4B84CB1DCD" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentBeforeTaxPortionAttributableToParentAbstract" xlink:label="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentBeforeTaxPortionAttributableToParentAbstract_791632CCF7130A6A3D941F4B84CB251B" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossBeforeTaxPortionAttributableToParentAbstract_1C1127441AF96D0B6C3D1F4B84CA2BAF" xlink:to="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentBeforeTaxPortionAttributableToParentAbstract_791632CCF7130A6A3D941F4B84CB251B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansNetUnamortizedGainLossArisingDuringPeriodBeforeTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansNetUnamortizedGainLossArisingDuringPeriodBeforeTax_598791E5C7A7DF9635F31F4B84CBE2AC" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentBeforeTaxPortionAttributableToParentAbstract_791632CCF7130A6A3D941F4B84CB251B" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansNetUnamortizedGainLossArisingDuringPeriodBeforeTax_598791E5C7A7DF9635F31F4B84CBE2AC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeTaxPortionAttributableToParent" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeTaxPortionAttributableToParent_90DD3FE7717ECF233FFC1F4B84CB516B" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_AA92993C7835F2953A5E1F4B84CA5DC0" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeTaxPortionAttributableToParent_90DD3FE7717ECF233FFC1F4B84CB516B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossTax_E525E33D7C184B155C851F4B84CB978A" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_AA92993C7835F2953A5E1F4B84CA5DC0" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossTax_E525E33D7C184B155C851F4B84CB978A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_299FA72F49420E2BC5501F4B84CB5CFC" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_AA92993C7835F2953A5E1F4B84CA5DC0" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_299FA72F49420E2BC5501F4B84CB5CFC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_3F4F0F450DDEFFD786B61F4B84CB34E5" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_AA92993C7835F2953A5E1F4B84CA5DC0" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_3F4F0F450DDEFFD786B61F4B84CB34E5" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/ConsolidatedStatementsOfOperations" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="loc_us-gaap_IncomeStatementAbstract_37E10E5FAC0799ACE8FB15B8C740A2A1" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SalesRevenueGoodsNet" xlink:label="loc_us-gaap_SalesRevenueGoodsNet_2F9E03B5828B55B6739315B8C7405B80" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_37E10E5FAC0799ACE8FB15B8C740A2A1" xlink:to="loc_us-gaap_SalesRevenueGoodsNet_2F9E03B5828B55B6739315B8C7405B80" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CostsAndExpensesAbstract" xlink:label="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_37E10E5FAC0799ACE8FB15B8C740A2A1" xlink:to="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CostOfGoodsSold" xlink:label="loc_us-gaap_CostOfGoodsSold_01B256F1FBF18132CB1415B8C7415507" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_CostOfGoodsSold_01B256F1FBF18132CB1415B8C7415507" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ResearchAndDevelopmentExpense" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_4B8A7E09A70D9C70710A15B8C74164BB" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_4B8A7E09A70D9C70710A15B8C74164BB" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpense" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_015B81254C4F4296A7FA15B8C7415983" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_015B81254C4F4296A7FA15B8C7415983" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AmortizationOfIntangibleAssets" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_17F3FFA62930F9D7442A15B8C7418C47" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_17F3FFA62930F9D7442A15B8C7418C47" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CostsAndExpenses" xlink:label="loc_us-gaap_CostsAndExpenses_3FE921653EBBDD8D376415B8C74190A5" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_CostsAndExpenses_3FE921653EBBDD8D376415B8C74190A5" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaap_OperatingIncomeLoss_E3B068313FC6797737A015B8C7415966" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_OperatingIncomeLoss_E3B068313FC6797737A015B8C7415966" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InvestmentIncomeInterest" xlink:label="loc_us-gaap_InvestmentIncomeInterest_C619D7C4CD195E319F0915B8C741DA8E" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_InvestmentIncomeInterest_C619D7C4CD195E319F0915B8C741DA8E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InterestExpense" xlink:label="loc_us-gaap_InterestExpense_33629629278644E43B3915B8C7414D66" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_InterestExpense_33629629278644E43B3915B8C7414D66" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherNonoperatingIncomeExpense" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_DE92717B470280D6DA9915B8C741BA83" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_DE92717B470280D6DA9915B8C741BA83" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_F11181050AB008D6EB2B15B8C7412ED2" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_F11181050AB008D6EB2B15B8C7412ED2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_EB8E773463779725F74F15B8C7415ECC" xlink:type="locator" />
    <presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_EB8E773463779725F74F15B8C7415ECC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromContinuingOperations" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperations_09FB414DABC321986F5F15B8C741A678" xlink:type="locator" />
    <presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperations_09FB414DABC321986F5F15B8C741A678" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_774ED46895233E3D383D15B8C741BD7B" xlink:type="locator" />
    <presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_774ED46895233E3D383D15B8C741BD7B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_91530166B24868E6F63F15B8C7414B1C" xlink:type="locator" />
    <presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_NetIncomeLoss_91530166B24868E6F63F15B8C7414B1C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsPerBasicShare" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsPerBasicShare_981D73EAFE67AA6C41B115B8C7417E81" xlink:type="locator" />
    <presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsPerBasicShare_981D73EAFE67AA6C41B115B8C7417E81" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationNetOfTaxPerBasicShare" xlink:label="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationNetOfTaxPerBasicShare_29F0756DEC90E5CB13E215B8C7419A8F" xlink:type="locator" />
    <presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationNetOfTaxPerBasicShare_29F0756DEC90E5CB13E215B8C7419A8F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EarningsPerShareBasic" xlink:label="loc_us-gaap_EarningsPerShareBasic_EAA09FB7406AE446744315B8C742A6EF" xlink:type="locator" />
    <presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_EarningsPerShareBasic_EAA09FB7406AE446744315B8C742A6EF" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare_5D247B8299D82661126C15B8C7428F4E" xlink:type="locator" />
    <presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare_5D247B8299D82661126C15B8C7428F4E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationNetOfTaxPerDilutedShare" xlink:label="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationNetOfTaxPerDilutedShare_68220DFC1099BF963FF815B8C742041F" xlink:type="locator" />
    <presentationArc order="19" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationNetOfTaxPerDilutedShare_68220DFC1099BF963FF815B8C742041F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EarningsPerShareDiluted" xlink:label="loc_us-gaap_EarningsPerShareDiluted_53F4EE3C599BFE33E61F15B8C7429053" xlink:type="locator" />
    <presentationArc order="20" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B88E2850D4319A0D328015B8C7406FFF" xlink:to="loc_us-gaap_EarningsPerShareDiluted_53F4EE3C599BFE33E61F15B8C7429053" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_B53B0B6110AF0C1245B315B8C742A4FC" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_37E10E5FAC0799ACE8FB15B8C740A2A1" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_B53B0B6110AF0C1245B315B8C742A4FC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_06E69525A80C6BAEE04415B8C7420EC6" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_B53B0B6110AF0C1245B315B8C742A4FC" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_06E69525A80C6BAEE04415B8C7420EC6" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_3A9069333C531994E04715B8C742D016" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_B53B0B6110AF0C1245B315B8C742A4FC" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_3A9069333C531994E04715B8C742D016" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/Debt" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_E47C27758B0A797FE6EB55ED59C5E33F" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtDisclosureTextBlock" xlink:label="loc_us-gaap_DebtDisclosureTextBlock_B637F703BAC6CCED87AE55ED59C5CD02" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_E47C27758B0A797FE6EB55ED59C5E33F" xlink:to="loc_us-gaap_DebtDisclosureTextBlock_B637F703BAC6CCED87AE55ED59C5CD02" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/DebtComponentsOfInterestExpenseDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_6BB5E234332EAABBC6CE9ECE577631C9" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="loc_us-gaap_DebtInstrumentTable_85EC06A5A4DE3179337C9ECE57768CD2" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_6BB5E234332EAABBC6CE9ECE577631C9" xlink:to="loc_us-gaap_DebtInstrumentTable_85EC06A5A4DE3179337C9ECE57768CD2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentAxis" xlink:label="loc_us-gaap_DebtInstrumentAxis_607812A53C23D808C1A19ECE5776B823" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_85EC06A5A4DE3179337C9ECE57768CD2" xlink:to="loc_us-gaap_DebtInstrumentAxis_607812A53C23D808C1A19ECE5776B823" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_829C80418B8C4B7C8F009ECE5777213E" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_607812A53C23D808C1A19ECE5776B823" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_829C80418B8C4B7C8F009ECE5777213E" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TwoThousandSixteenSeniorConvertibleNotesMember" xlink:label="loc_iart_TwoThousandSixteenSeniorConvertibleNotesMember_D26819633016314BD67B9ECE577798C5" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_829C80418B8C4B7C8F009ECE5777213E" xlink:to="loc_iart_TwoThousandSixteenSeniorConvertibleNotesMember_D26819633016314BD67B9ECE577798C5" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="loc_us-gaap_DebtInstrumentLineItems_ECC3B8B92E31B4D4E2279ECE577748EF" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_85EC06A5A4DE3179337C9ECE57768CD2" xlink:to="loc_us-gaap_DebtInstrumentLineItems_ECC3B8B92E31B4D4E2279ECE577748EF" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AmortizationOfDebtDiscountPremium" xlink:label="loc_us-gaap_AmortizationOfDebtDiscountPremium_A74DFF1BC29E88B052C59ECE577778F8" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_ECC3B8B92E31B4D4E2279ECE577748EF" xlink:to="loc_us-gaap_AmortizationOfDebtDiscountPremium_A74DFF1BC29E88B052C59ECE577778F8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InterestExpenseDebtExcludingAmortization" xlink:label="loc_us-gaap_InterestExpenseDebtExcludingAmortization_3DA7CFD52C09787F340D9ECE577789DD" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_ECC3B8B92E31B4D4E2279ECE577748EF" xlink:to="loc_us-gaap_InterestExpenseDebtExcludingAmortization_3DA7CFD52C09787F340D9ECE577789DD" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InterestExpenseDebt" xlink:label="loc_us-gaap_InterestExpenseDebt_9BA87513C0FB2200B9259ECE577736AC" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_ECC3B8B92E31B4D4E2279ECE577748EF" xlink:to="loc_us-gaap_InterestExpenseDebt_9BA87513C0FB2200B9259ECE577736AC" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_AmortizationOfDebtDiscountPremiumInterestCostsCapitalized" xlink:label="loc_iart_AmortizationOfDebtDiscountPremiumInterestCostsCapitalized_F08D765B8F579E7C57B19ECE57774F9A" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_ECC3B8B92E31B4D4E2279ECE577748EF" xlink:to="loc_iart_AmortizationOfDebtDiscountPremiumInterestCostsCapitalized_F08D765B8F579E7C57B19ECE57774F9A" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_InterestExpenseDebtExcludingAmortizationInterestCostsCapitalized" xlink:label="loc_iart_InterestExpenseDebtExcludingAmortizationInterestCostsCapitalized_BCB15B9651EE95191A319ECE57775E6E" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_ECC3B8B92E31B4D4E2279ECE577748EF" xlink:to="loc_iart_InterestExpenseDebtExcludingAmortizationInterestCostsCapitalized_BCB15B9651EE95191A319ECE57775E6E" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/DebtNarrativeDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="loc_us-gaap_DebtInstrumentTable_3E65B36801F3F8239492197704E7E823" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_VariableRateAxis" xlink:label="loc_us-gaap_VariableRateAxis_7FA7898FE47D836BCDC3197704E88A3F" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_3E65B36801F3F8239492197704E7E823" xlink:to="loc_us-gaap_VariableRateAxis_7FA7898FE47D836BCDC3197704E88A3F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_VariableRateDomain" xlink:label="loc_us-gaap_VariableRateDomain_7BBCDDE3D1FC9A071DCB197704E89499" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateAxis_7FA7898FE47D836BCDC3197704E88A3F" xlink:to="loc_us-gaap_VariableRateDomain_7BBCDDE3D1FC9A071DCB197704E89499" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EurodollarMember" xlink:label="loc_us-gaap_EurodollarMember_456775843D554ACFE035197704E80BAF" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateDomain_7BBCDDE3D1FC9A071DCB197704E89499" xlink:to="loc_us-gaap_EurodollarMember_456775843D554ACFE035197704E80BAF" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_FederalFundsMember" xlink:label="loc_iart_FederalFundsMember_840A8A98CB6E3AFCA44B197704E8F336" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateDomain_7BBCDDE3D1FC9A071DCB197704E89499" xlink:to="loc_iart_FederalFundsMember_840A8A98CB6E3AFCA44B197704E8F336" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LondonInterbankOfferedRateLIBORMember" xlink:label="loc_us-gaap_LondonInterbankOfferedRateLIBORMember_B3DAB221A01C9B9A2CF7197704E8BC99" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateDomain_7BBCDDE3D1FC9A071DCB197704E89499" xlink:to="loc_us-gaap_LondonInterbankOfferedRateLIBORMember_B3DAB221A01C9B9A2CF7197704E8BC99" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_D00228041F40F47361E7197704E83D4E" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_3E65B36801F3F8239492197704E7E823" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_D00228041F40F47361E7197704E83D4E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_AFF1DD75B9DB791EC79E197704E8CB4E" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_D00228041F40F47361E7197704E83D4E" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_AFF1DD75B9DB791EC79E197704E8CB4E" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TermLoanMember" xlink:label="loc_iart_TermLoanMember_8D4825DD7B20F0CB25C3197704ED73BB" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_AFF1DD75B9DB791EC79E197704E8CB4E" xlink:to="loc_iart_TermLoanMember_8D4825DD7B20F0CB25C3197704ED73BB" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ConvertibleDebtMember" xlink:label="loc_us-gaap_ConvertibleDebtMember_0F53E7706AE1866AECBB197704ED494F" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_AFF1DD75B9DB791EC79E197704E8CB4E" xlink:to="loc_us-gaap_ConvertibleDebtMember_0F53E7706AE1866AECBB197704ED494F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CreditFacilityAxis" xlink:label="loc_us-gaap_CreditFacilityAxis_7B91037C4270BEC9C19E197704EDED09" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_3E65B36801F3F8239492197704E7E823" xlink:to="loc_us-gaap_CreditFacilityAxis_7B91037C4270BEC9C19E197704EDED09" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="loc_us-gaap_CreditFacilityDomain_71AB03EF4C1D8A888E1F197704EDDCF0" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityAxis_7B91037C4270BEC9C19E197704EDED09" xlink:to="loc_us-gaap_CreditFacilityDomain_71AB03EF4C1D8A888E1F197704EDDCF0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RevolvingCreditFacilityMember" xlink:label="loc_us-gaap_RevolvingCreditFacilityMember_4B6CBF4AD12DB507E440197704EE175E" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_71AB03EF4C1D8A888E1F197704EDDCF0" xlink:to="loc_us-gaap_RevolvingCreditFacilityMember_4B6CBF4AD12DB507E440197704EE175E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StandbyLettersOfCreditMember" xlink:label="loc_us-gaap_StandbyLettersOfCreditMember_AD05D3B5AAC058BF1A86197704EEDBDD" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_71AB03EF4C1D8A888E1F197704EDDCF0" xlink:to="loc_us-gaap_StandbyLettersOfCreditMember_AD05D3B5AAC058BF1A86197704EEDBDD" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SwinglineLoanMember" xlink:label="loc_iart_SwinglineLoanMember_810581D6DDD9CC4D5199197704EE13A7" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_71AB03EF4C1D8A888E1F197704EDDCF0" xlink:to="loc_iart_SwinglineLoanMember_810581D6DDD9CC4D5199197704EE13A7" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentAxis" xlink:label="loc_us-gaap_DebtInstrumentAxis_0CBBAA4BC09D7CEB441A197704EE7ED7" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_3E65B36801F3F8239492197704E7E823" xlink:to="loc_us-gaap_DebtInstrumentAxis_0CBBAA4BC09D7CEB441A197704EE7ED7" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_A1C5089E29B8AFB82B45197704EEA849" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_0CBBAA4BC09D7CEB441A197704EE7ED7" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_A1C5089E29B8AFB82B45197704EEA849" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_JulyTwoThousandFourteenAmendmentMember" xlink:label="loc_iart_JulyTwoThousandFourteenAmendmentMember_A2808234F697B18AD7FD197704EE9ADC" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_A1C5089E29B8AFB82B45197704EEA849" xlink:to="loc_iart_JulyTwoThousandFourteenAmendmentMember_A2808234F697B18AD7FD197704EE9ADC" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_AugustTwoThousandFifteenAmendmentMember" xlink:label="loc_iart_AugustTwoThousandFifteenAmendmentMember_ED7D32D3C183AE76D069197704EE6C82" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_A1C5089E29B8AFB82B45197704EEA849" xlink:to="loc_iart_AugustTwoThousandFifteenAmendmentMember_ED7D32D3C183AE76D069197704EE6C82" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SeniorCreditFacilityMember" xlink:label="loc_iart_SeniorCreditFacilityMember_BBDAFC5948FF24D90BA0197704EEFDF0" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_A1C5089E29B8AFB82B45197704EEA849" xlink:to="loc_iart_SeniorCreditFacilityMember_BBDAFC5948FF24D90BA0197704EEFDF0" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TwoThousandSixteenSeniorConvertibleNotesMember" xlink:label="loc_iart_TwoThousandSixteenSeniorConvertibleNotesMember_A971AC469E0CCA860684197704EE2E58" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_A1C5089E29B8AFB82B45197704EEA849" xlink:to="loc_iart_TwoThousandSixteenSeniorConvertibleNotesMember_A971AC469E0CCA860684197704EE2E58" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RangeAxis" xlink:label="loc_us-gaap_RangeAxis_116149ADFD9A1B149A19197704EEB7D7" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_3E65B36801F3F8239492197704E7E823" xlink:to="loc_us-gaap_RangeAxis_116149ADFD9A1B149A19197704EEB7D7" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_20F135053044265C2250197704EE2051" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeAxis_116149ADFD9A1B149A19197704EEB7D7" xlink:to="loc_us-gaap_RangeMember_20F135053044265C2250197704EE2051" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_MinimumMember" xlink:label="loc_us-gaap_MinimumMember_3DD1D89E195272A56D24197704EE31B5" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeMember_20F135053044265C2250197704EE2051" xlink:to="loc_us-gaap_MinimumMember_3DD1D89E195272A56D24197704EE31B5" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_MaximumMember" xlink:label="loc_us-gaap_MaximumMember_F14FDAC1B0B1809155E1197704EE27B3" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeMember_20F135053044265C2250197704EE2051" xlink:to="loc_us-gaap_MaximumMember_F14FDAC1B0B1809155E1197704EE27B3" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_3E65B36801F3F8239492197704E7E823" xlink:to="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity" xlink:label="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_8637A7D8188E5CB33996197704EEAC1F" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_8637A7D8188E5CB33996197704EEAC1F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ProceedsFromLinesOfCredit" xlink:label="loc_us-gaap_ProceedsFromLinesOfCredit_5226585D7ECCCAFB3B99197704EE242F" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_ProceedsFromLinesOfCredit_5226585D7ECCCAFB3B99197704EE242F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentBasisSpreadOnVariableRate1" xlink:label="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_34A9001E67EC9353F4B3197704EEA66C" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_34A9001E67EC9353F4B3197704EEA66C" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_CashBalanceThresholdAboveWhichExcessCashIsNotSubjectToRestrictionOfUse" xlink:label="loc_iart_CashBalanceThresholdAboveWhichExcessCashIsNotSubjectToRestrictionOfUse_F1AF9B9B9A7942362932197704EF5F1E" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_iart_CashBalanceThresholdAboveWhichExcessCashIsNotSubjectToRestrictionOfUse_F1AF9B9B9A7942362932197704EF5F1E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LineOfCreditFacilityCommitmentFeePercentage" xlink:label="loc_us-gaap_LineOfCreditFacilityCommitmentFeePercentage_AF805EE31C400CBF6015197704EF1974" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_LineOfCreditFacilityCommitmentFeePercentage_AF805EE31C400CBF6015197704EF1974" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredFinanceCostsGross" xlink:label="loc_us-gaap_DeferredFinanceCostsGross_29B63560F023D7BC93E5197704EFA66D" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_DeferredFinanceCostsGross_29B63560F023D7BC93E5197704EFA66D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AmortizationOfFinancingCosts" xlink:label="loc_us-gaap_AmortizationOfFinancingCosts_BFF89B13ACBED8498580197704EF3BC3" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_AmortizationOfFinancingCosts_BFF89B13ACBED8498580197704EF3BC3" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LineOfCredit" xlink:label="loc_us-gaap_LineOfCredit_02AA2AB62C317EFC097C197704EF1333" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_LineOfCredit_02AA2AB62C317EFC097C197704EF1333" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtWeightedAverageInterestRate" xlink:label="loc_us-gaap_DebtWeightedAverageInterestRate_3C0F268878D025ECE248197704EFC8D5" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_DebtWeightedAverageInterestRate_3C0F268878D025ECE248197704EFC8D5" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TermLoanAmountOutstanding" xlink:label="loc_iart_TermLoanAmountOutstanding_53ACAC2B3260F3A3E226197704EF05C3" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_iart_TermLoanAmountOutstanding_53ACAC2B3260F3A3E226197704EF05C3" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LineOfCreditFacilityRemainingBorrowingCapacity" xlink:label="loc_us-gaap_LineOfCreditFacilityRemainingBorrowingCapacity_9CB6982452485234E3BA197704EFEE30" xlink:type="locator" />
    <presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_LineOfCreditFacilityRemainingBorrowingCapacity_9CB6982452485234E3BA197704EFEE30" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentFairValue" xlink:label="loc_us-gaap_DebtInstrumentFairValue_FAD7E70D63905E59DA45197704EF10E7" xlink:type="locator" />
    <presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_DebtInstrumentFairValue_FAD7E70D63905E59DA45197704EF10E7" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentFaceAmount" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_565F070B6645CD4252BD197704EFFAF3" xlink:type="locator" />
    <presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_565F070B6645CD4252BD197704EFFAF3" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_5552F03062FEBA136EDA197704EF96F0" xlink:type="locator" />
    <presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_5552F03062FEBA136EDA197704EF96F0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentConvertibleCarryingAmountOfTheEquityComponent" xlink:label="loc_us-gaap_DebtInstrumentConvertibleCarryingAmountOfTheEquityComponent_4FF5D3DBEBD99286AE84197704EFD48B" xlink:type="locator" />
    <presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_DebtInstrumentConvertibleCarryingAmountOfTheEquityComponent_4FF5D3DBEBD99286AE84197704EFD48B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage" xlink:label="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_3FFAF72329C33F6FB7CC197704EF0E28" xlink:type="locator" />
    <presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_3FFAF72329C33F6FB7CC197704EF0E28" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ConvertibleDebtNoncurrent" xlink:label="loc_us-gaap_ConvertibleDebtNoncurrent_49BB10E8EDC475EC69C6197704EFB1EB" xlink:type="locator" />
    <presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_ConvertibleDebtNoncurrent_49BB10E8EDC475EC69C6197704EFB1EB" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentUnamortizedDiscount" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedDiscount_09BD7F44D05AB2258025197704EF767F" xlink:type="locator" />
    <presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_DebtInstrumentUnamortizedDiscount_09BD7F44D05AB2258025197704EF767F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentConvertibleConversionRatio1" xlink:label="loc_us-gaap_DebtInstrumentConvertibleConversionRatio1_D152FE0D32F0A201D991197704EF374E" xlink:type="locator" />
    <presentationArc order="19" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_DebtInstrumentConvertibleConversionRatio1_D152FE0D32F0A201D991197704EF374E" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_PrincipalAmountToBeConsideredForConversionPurpose" xlink:label="loc_iart_PrincipalAmountToBeConsideredForConversionPurpose_3812228020C61D610AA8197704EF5668" xlink:type="locator" />
    <presentationArc order="20" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_iart_PrincipalAmountToBeConsideredForConversionPurpose_3812228020C61D610AA8197704EF5668" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentConvertibleConversionPrice1" xlink:label="loc_us-gaap_DebtInstrumentConvertibleConversionPrice1_F04BCCAFF6999E18856A197704EF8052" xlink:type="locator" />
    <presentationArc order="21" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_DebtInstrumentConvertibleConversionPrice1_F04BCCAFF6999E18856A197704EF8052" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_MaximumSellingPriceOfCompanysCommonStock" xlink:label="loc_iart_MaximumSellingPriceOfCompanysCommonStock_1D3589E67F5939ED0B53197704EF8FA6" xlink:type="locator" />
    <presentationArc order="22" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_iart_MaximumSellingPriceOfCompanysCommonStock_1D3589E67F5939ED0B53197704EF8FA6" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_PrincipalAmountOfNotesPerAverageTradingPrice" xlink:label="loc_iart_PrincipalAmountOfNotesPerAverageTradingPrice_B4C6103680CAAF419538197704EF9F57" xlink:type="locator" />
    <presentationArc order="23" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_iart_PrincipalAmountOfNotesPerAverageTradingPrice_B4C6103680CAAF419538197704EF9F57" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_MaximumAverageConversionValueOfNotes" xlink:label="loc_iart_MaximumAverageConversionValueOfNotes_4553B9D274AE8ADCDA61197704EFD809" xlink:type="locator" />
    <presentationArc order="24" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_iart_MaximumAverageConversionValueOfNotes_4553B9D274AE8ADCDA61197704EFD809" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_EarliestConversionDate" xlink:label="loc_iart_EarliestConversionDate_C33372ACB919802F2A00197704F06D12" xlink:type="locator" />
    <presentationArc order="25" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_iart_EarliestConversionDate_C33372ACB919802F2A00197704F06D12" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DebtInstrumentConvertibleNumberofDebtInstrumentsPendingConversion" xlink:label="loc_iart_DebtInstrumentConvertibleNumberofDebtInstrumentsPendingConversion_871DD44140F45143BD01197704F0AFB3" xlink:type="locator" />
    <presentationArc order="26" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_iart_DebtInstrumentConvertibleNumberofDebtInstrumentsPendingConversion_871DD44140F45143BD01197704F0AFB3" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RepaymentsOfDebt" xlink:label="loc_us-gaap_RepaymentsOfDebt_748379ACA20965419993197704F0E86C" xlink:type="locator" />
    <presentationArc order="27" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_RepaymentsOfDebt_748379ACA20965419993197704F0E86C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities_62BD22D9449205A77F6D197704F08A73" xlink:type="locator" />
    <presentationArc order="28" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities_62BD22D9449205A77F6D197704F08A73" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DerivativePriceOfCallTransactionStrikePrice" xlink:label="loc_iart_DerivativePriceOfCallTransactionStrikePrice_5ECD84CC8E05C936CC5C197704F5F516" xlink:type="locator" />
    <presentationArc order="29" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_iart_DerivativePriceOfCallTransactionStrikePrice_5ECD84CC8E05C936CC5C197704F5F516" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_StrikePriceOfWarrantTransactions" xlink:label="loc_iart_StrikePriceOfWarrantTransactions_22F23BED540BD0D9FB26197704F5D87B" xlink:type="locator" />
    <presentationArc order="30" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_iart_StrikePriceOfWarrantTransactions_22F23BED540BD0D9FB26197704F5D87B" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_AmortizationOfDebtDiscountPremiumInterestCostsCapitalized" xlink:label="loc_iart_AmortizationOfDebtDiscountPremiumInterestCostsCapitalized_CE488285451A01C3A7C6197704F55442" xlink:type="locator" />
    <presentationArc order="31" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_iart_AmortizationOfDebtDiscountPremiumInterestCostsCapitalized_CE488285451A01C3A7C6197704F55442" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_InterestExpenseDebtExcludingAmortizationInterestCostsCapitalized" xlink:label="loc_iart_InterestExpenseDebtExcludingAmortizationInterestCostsCapitalized_EBCDF9C4770A892663E5197704F5D10A" xlink:type="locator" />
    <presentationArc order="32" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_2A634DD5A707D8B62372197704EE796F" xlink:to="loc_iart_InterestExpenseDebtExcludingAmortizationInterestCostsCapitalized_EBCDF9C4770A892663E5197704F5D10A" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/DebtScheduleOfDebtMaturityDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_EDBF43682D86F3AD8F5E51E70E847C8B" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="loc_us-gaap_DebtInstrumentTable_0D3E4D45ABB18651B3B351E70E84CF43" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_EDBF43682D86F3AD8F5E51E70E847C8B" xlink:to="loc_us-gaap_DebtInstrumentTable_0D3E4D45ABB18651B3B351E70E84CF43" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SeniorCreditFacilityAxis" xlink:label="loc_iart_SeniorCreditFacilityAxis_731867211A9BD0DF556451E70E846587" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_0D3E4D45ABB18651B3B351E70E84CF43" xlink:to="loc_iart_SeniorCreditFacilityAxis_731867211A9BD0DF556451E70E846587" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SeniorCreditFacilityDomain" xlink:label="loc_iart_SeniorCreditFacilityDomain_82B5885B0A557C9555E651E70E845D1A" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SeniorCreditFacilityAxis_731867211A9BD0DF556451E70E846587" xlink:to="loc_iart_SeniorCreditFacilityDomain_82B5885B0A557C9555E651E70E845D1A" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TermLoanMember" xlink:label="loc_iart_TermLoanMember_FBBA759B8D63A617CFC651E70E84B7BB" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SeniorCreditFacilityDomain_82B5885B0A557C9555E651E70E845D1A" xlink:to="loc_iart_TermLoanMember_FBBA759B8D63A617CFC651E70E84B7BB" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="loc_us-gaap_DebtInstrumentLineItems_942F3C7B173FB4FDC40D51E70E84DC69" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_0D3E4D45ABB18651B3B351E70E84CF43" xlink:to="loc_us-gaap_DebtInstrumentLineItems_942F3C7B173FB4FDC40D51E70E84DC69" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths_A6E9761309B1B0A715DE51E70E84D396" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_942F3C7B173FB4FDC40D51E70E84DC69" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths_A6E9761309B1B0A715DE51E70E84D396" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo_B6E44DDF5D4D91DE8B1451E70E84C84E" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_942F3C7B173FB4FDC40D51E70E84DC69" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo_B6E44DDF5D4D91DE8B1451E70E84C84E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree_3D5E9BAB5796C806118151E70E840450" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_942F3C7B173FB4FDC40D51E70E84DC69" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree_3D5E9BAB5796C806118151E70E840450" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_9781B7CEE1E3A7274BDD51E70E847B3B" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_942F3C7B173FB4FDC40D51E70E84DC69" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_9781B7CEE1E3A7274BDD51E70E847B3B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFive" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFive_6E4C508F5E11E6DB817A51E70E84DD38" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_942F3C7B173FB4FDC40D51E70E84DC69" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFive_6E4C508F5E11E6DB817A51E70E84DD38" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/DebtTables" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_E2D1C276ACAD94E67F81461736A0B324" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfMaturitiesOfLongTermDebtTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfMaturitiesOfLongTermDebtTableTextBlock_BF08B4742516DB4B5E91461736A06BC8" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_E2D1C276ACAD94E67F81461736A0B324" xlink:to="loc_us-gaap_ScheduleOfMaturitiesOfLongTermDebtTableTextBlock_BF08B4742516DB4B5E91461736A06BC8" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_ComponentsOfInterestExpenseTableTableTextBlock" xlink:label="loc_iart_ComponentsOfInterestExpenseTableTableTextBlock_D49C4554F96412252E8346430C718196" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_E2D1C276ACAD94E67F81461736A0B324" xlink:to="loc_iart_ComponentsOfInterestExpenseTableTableTextBlock_D49C4554F96412252E8346430C718196" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/DerivativeInstruments" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_0A2A9545C3B69C58E72355ED595E2D99" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock_7B79257073AD52F9437155ED595E0AB1" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_0A2A9545C3B69C58E72355ED595E2D99" xlink:to="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock_7B79257073AD52F9437155ED595E0AB1" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/DerivativeInstrumentsEffectOfDerivativeInstrumentsDesignatedCashFlowHedgesOnStatementsOfOperationsDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_CBB48E192DDCFB0CFC60F0D3751B921D" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_4141034A1A16CF4700C1F0D3751B8FA8" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_CBB48E192DDCFB0CFC60F0D3751B921D" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_4141034A1A16CF4700C1F0D3751B8FA8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_3FF5E28368F21503C6B5F0D3751B078A" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_4141034A1A16CF4700C1F0D3751B8FA8" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_3FF5E28368F21503C6B5F0D3751B078A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_9CE93EDC94289103A3A5F0D3751B0024" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_3FF5E28368F21503C6B5F0D3751B078A" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_9CE93EDC94289103A3A5F0D3751B0024" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InterestExpenseMember" xlink:label="loc_us-gaap_InterestExpenseMember_CF571A3AAC04655AFB45F0D3751BB771" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_9CE93EDC94289103A3A5F0D3751B0024" xlink:to="loc_us-gaap_InterestExpenseMember_CF571A3AAC04655AFB45F0D3751BB771" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeByNatureAxis" xlink:label="loc_us-gaap_DerivativeByNatureAxis_CD27B205D0A94B1E7D99F0D3751BF435" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_4141034A1A16CF4700C1F0D3751B8FA8" xlink:to="loc_us-gaap_DerivativeByNatureAxis_CD27B205D0A94B1E7D99F0D3751BF435" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeNameDomain" xlink:label="loc_us-gaap_DerivativeNameDomain_B39EEACCA751F951D3B9F0D3751B3276" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeByNatureAxis_CD27B205D0A94B1E7D99F0D3751BF435" xlink:to="loc_us-gaap_DerivativeNameDomain_B39EEACCA751F951D3B9F0D3751B3276" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InterestRateSwapMember" xlink:label="loc_us-gaap_InterestRateSwapMember_2E3CD56BF537CC6AA520F0D3751B0DC2" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeNameDomain_B39EEACCA751F951D3B9F0D3751B3276" xlink:to="loc_us-gaap_InterestRateSwapMember_2E3CD56BF537CC6AA520F0D3751B0DC2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_51861168D84AD823B838F0D3751CEB8A" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_4141034A1A16CF4700C1F0D3751B8FA8" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_51861168D84AD823B838F0D3751CEB8A" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_AccumulatedOtherComprehensiveIncomeLossRollForward" xlink:label="loc_iart_AccumulatedOtherComprehensiveIncomeLossRollForward_8C7011C59D0CC4E868DCF0D3751C0B88" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_51861168D84AD823B838F0D3751CEB8A" xlink:to="loc_iart_AccumulatedOtherComprehensiveIncomeLossRollForward_8C7011C59D0CC4E868DCF0D3751C0B88" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_AccumulatedOtherComprehensiveIncomeLossCumulativeChangesInNetGainLossFromCashFlowHedgeEffectBeforeTax" xlink:label="loc_iart_AccumulatedOtherComprehensiveIncomeLossCumulativeChangesInNetGainLossFromCashFlowHedgeEffectBeforeTax_67AE0728D35F49122C81F0D3751C4D5D" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_AccumulatedOtherComprehensiveIncomeLossRollForward_8C7011C59D0CC4E868DCF0D3751C0B88" xlink:to="loc_iart_AccumulatedOtherComprehensiveIncomeLossCumulativeChangesInNetGainLossFromCashFlowHedgeEffectBeforeTax_67AE0728D35F49122C81F0D3751C4D5D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossRecognizedInOtherComprehensiveIncomeEffectivePortionNet" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossRecognizedInOtherComprehensiveIncomeEffectivePortionNet_4DE43BCDD93630BEE976F0D3751C5E67" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_AccumulatedOtherComprehensiveIncomeLossRollForward_8C7011C59D0CC4E868DCF0D3751C0B88" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossRecognizedInOtherComprehensiveIncomeEffectivePortionNet_4DE43BCDD93630BEE976F0D3751C5E67" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossReclassifiedFromAccumulatedOCIIntoIncomeEffectivePortionNet" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossReclassifiedFromAccumulatedOCIIntoIncomeEffectivePortionNet_42FEAF56B5B47F5FEC05F0D3751C6D48" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_AccumulatedOtherComprehensiveIncomeLossRollForward_8C7011C59D0CC4E868DCF0D3751C0B88" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossReclassifiedFromAccumulatedOCIIntoIncomeEffectivePortionNet_42FEAF56B5B47F5FEC05F0D3751C6D48" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_AccumulatedOtherComprehensiveIncomeLossCumulativeChangesInNetGainLossFromCashFlowHedgeEffectBeforeTax" xlink:label="loc_iart_AccumulatedOtherComprehensiveIncomeLossCumulativeChangesInNetGainLossFromCashFlowHedgeEffectBeforeTax_B26689F01DB997B07EC3F0D3751C9D7B" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_AccumulatedOtherComprehensiveIncomeLossRollForward_8C7011C59D0CC4E868DCF0D3751C0B88" xlink:to="loc_iart_AccumulatedOtherComprehensiveIncomeLossCumulativeChangesInNetGainLossFromCashFlowHedgeEffectBeforeTax_B26689F01DB997B07EC3F0D3751C9D7B" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/DerivativeInstrumentsNarrativeDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_F34259B88C558FFAC96A3CC653E95212" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeTable" xlink:label="loc_us-gaap_DerivativeTable_22590B88F80AD725D9F93CC653E96165" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_F34259B88C558FFAC96A3CC653E95212" xlink:to="loc_us-gaap_DerivativeTable_22590B88F80AD725D9F93CC653E96165" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeByNatureAxis" xlink:label="loc_us-gaap_DerivativeByNatureAxis_A81C6A1F86D407F114E23CC653E9E594" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeTable_22590B88F80AD725D9F93CC653E96165" xlink:to="loc_us-gaap_DerivativeByNatureAxis_A81C6A1F86D407F114E23CC653E9E594" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeNameDomain" xlink:label="loc_us-gaap_DerivativeNameDomain_100AC9BAFB7A836F0A203CC653E96850" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeByNatureAxis_A81C6A1F86D407F114E23CC653E9E594" xlink:to="loc_us-gaap_DerivativeNameDomain_100AC9BAFB7A836F0A203CC653E96850" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InterestRateSwapMember" xlink:label="loc_us-gaap_InterestRateSwapMember_C975B3C9DE76A4EBE1553CC653E9E661" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeNameDomain_100AC9BAFB7A836F0A203CC653E96850" xlink:to="loc_us-gaap_InterestRateSwapMember_C975B3C9DE76A4EBE1553CC653E9E661" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeLineItems" xlink:label="loc_us-gaap_DerivativeLineItems_0726537FC6B039F7333F3CC653E93617" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeTable_22590B88F80AD725D9F93CC653E96165" xlink:to="loc_us-gaap_DerivativeLineItems_0726537FC6B039F7333F3CC653E93617" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossReclassificationFromAccumulatedOCIToIncomeEstimatedNetAmountToBeTransferred" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossReclassificationFromAccumulatedOCIToIncomeEstimatedNetAmountToBeTransferred_D60F4653F810384E704A3CC653E95299" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeLineItems_0726537FC6B039F7333F3CC653E93617" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossReclassificationFromAccumulatedOCIToIncomeEstimatedNetAmountToBeTransferred_D60F4653F810384E704A3CC653E95299" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeNetHedgeIneffectivenessGainLoss" xlink:label="loc_us-gaap_DerivativeNetHedgeIneffectivenessGainLoss_F7E9DA2B2CC9D7D1CEF33CC653E91954" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeLineItems_0726537FC6B039F7333F3CC653E93617" xlink:to="loc_us-gaap_DerivativeNetHedgeIneffectivenessGainLoss_F7E9DA2B2CC9D7D1CEF33CC653E91954" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/DerivativeInstrumentsSummaryOfFairValueInBalanceSheetForDerivativesDesignatedHedgingInstrumentsDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_D0D87D6366F5C285309955ED59426D0C" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeTable" xlink:label="loc_us-gaap_DerivativeTable_E85674AC904141AFEF1A55ED5942957E" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_D0D87D6366F5C285309955ED59426D0C" xlink:to="loc_us-gaap_DerivativeTable_E85674AC904141AFEF1A55ED5942957E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeByNatureAxis" xlink:label="loc_us-gaap_DerivativeByNatureAxis_E62EAD75E5296884AA2455ED59426944" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeTable_E85674AC904141AFEF1A55ED5942957E" xlink:to="loc_us-gaap_DerivativeByNatureAxis_E62EAD75E5296884AA2455ED59426944" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeNameDomain" xlink:label="loc_us-gaap_DerivativeNameDomain_9E74400EF4C4C7A0959955ED59471E44" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeByNatureAxis_E62EAD75E5296884AA2455ED59426944" xlink:to="loc_us-gaap_DerivativeNameDomain_9E74400EF4C4C7A0959955ED59471E44" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InterestRateSwapMember" xlink:label="loc_us-gaap_InterestRateSwapMember_F6AA4AA796E28C5FBD6E55ED5947F2C6" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeNameDomain_9E74400EF4C4C7A0959955ED59471E44" xlink:to="loc_us-gaap_InterestRateSwapMember_F6AA4AA796E28C5FBD6E55ED5947F2C6" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BalanceSheetLocationAxis" xlink:label="loc_us-gaap_BalanceSheetLocationAxis_537677E98317B998336555ED5947EE34" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeTable_E85674AC904141AFEF1A55ED5942957E" xlink:to="loc_us-gaap_BalanceSheetLocationAxis_537677E98317B998336555ED5947EE34" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BalanceSheetLocationDomain" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_2A2F56B49EA224CEAD4A55ED594853B0" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_537677E98317B998336555ED5947EE34" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_2A2F56B49EA224CEAD4A55ED594853B0" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_AccruedExpensesAndOtherCurrentLiabilitiesMember" xlink:label="loc_iart_AccruedExpensesAndOtherCurrentLiabilitiesMember_AA3C9F682620C87205CD55ED59483D16" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_2A2F56B49EA224CEAD4A55ED594853B0" xlink:to="loc_iart_AccruedExpensesAndOtherCurrentLiabilitiesMember_AA3C9F682620C87205CD55ED59483D16" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DerivativeInstrumentsAndHedgingActivitiesDisclosureLineItems" xlink:label="loc_iart_DerivativeInstrumentsAndHedgingActivitiesDisclosureLineItems_C3FE6022221C3DF9D79855ED59489142" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeTable_E85674AC904141AFEF1A55ED5942957E" xlink:to="loc_iart_DerivativeInstrumentsAndHedgingActivitiesDisclosureLineItems_C3FE6022221C3DF9D79855ED59489142" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeLiability" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_FC1AE7DDBB513B89210A55ED59489F86" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DerivativeInstrumentsAndHedgingActivitiesDisclosureLineItems_C3FE6022221C3DF9D79855ED59489142" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_FC1AE7DDBB513B89210A55ED59489F86" xlink:type="arc" />
    <loc xlink:href="http://xbrl.sec.gov/invest/2013/invest-2013-01-31.xsd#invest_DerivativeNotionalAmount" xlink:label="loc_invest_DerivativeNotionalAmount_4ADBB927BFF8FD55801855ED59483DC6" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DerivativeInstrumentsAndHedgingActivitiesDisclosureLineItems_C3FE6022221C3DF9D79855ED59489142" xlink:to="loc_invest_DerivativeNotionalAmount_4ADBB927BFF8FD55801855ED59483DC6" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/DerivativeInstrumentsTables" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_1196AA535E17077CA7B63C03A419054D" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock" xlink:label="loc_us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock_107DFC4F583D7A1E5B0D3C03A4198D98" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_1196AA535E17077CA7B63C03A419054D" xlink:to="loc_us-gaap_ScheduleOfDerivativeInstrumentsInStatementOfFinancialPositionFairValueTextBlock_107DFC4F583D7A1E5B0D3C03A4198D98" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfDerivativeInstrumentsGainLossInStatementOfFinancialPerformanceTextBlock" xlink:label="loc_us-gaap_ScheduleOfDerivativeInstrumentsGainLossInStatementOfFinancialPerformanceTextBlock_659D9FAB525B75C6CCDE3C03A419F8E7" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_1196AA535E17077CA7B63C03A419054D" xlink:to="loc_us-gaap_ScheduleOfDerivativeInstrumentsGainLossInStatementOfFinancialPerformanceTextBlock_659D9FAB525B75C6CCDE3C03A419F8E7" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/DiscontinuedOperations" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_D10EEF0D4D9CE2F2DAC01A9D63ED2F56" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsDisclosureTextBlock" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsDisclosureTextBlock_502646428E0181755DCF1A9D63ED5009" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_D10EEF0D4D9CE2F2DAC01A9D63ED2F56" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsDisclosureTextBlock_502646428E0181755DCF1A9D63ED5009" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/DiscontinuedOperationsNarrativeDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_DC968D35A7C1FD713BA4F0D375F0E0C2" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_D15763A6507519A63173F0D375F0AAB8" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_DC968D35A7C1FD713BA4F0D375F0E0C2" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_D15763A6507519A63173F0D375F0AAB8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis" xlink:label="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_CBB8CBCC2AF67F30B503F0D375F0A669" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_D15763A6507519A63173F0D375F0AAB8" xlink:to="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_CBB8CBCC2AF67F30B503F0D375F0A669" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RelatedPartyDomain" xlink:label="loc_us-gaap_RelatedPartyDomain_7B4966A6ED283646C199F0D375F02277" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_CBB8CBCC2AF67F30B503F0D375F0A669" xlink:to="loc_us-gaap_RelatedPartyDomain_7B4966A6ED283646C199F0D375F02277" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DirectorMember" xlink:label="loc_us-gaap_DirectorMember_BD61CB3E0064CE6E25FEF0D375F02574" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyDomain_7B4966A6ED283646C199F0D375F02277" xlink:to="loc_us-gaap_DirectorMember_BD61CB3E0064CE6E25FEF0D375F02574" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_E5D8419DDA0E87F93392F0D375F0002E" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_D15763A6507519A63173F0D375F0AAB8" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_E5D8419DDA0E87F93392F0D375F0002E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_582A5EAA4D1AEFF2D611F0D375F0AD2D" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_E5D8419DDA0E87F93392F0D375F0002E" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_582A5EAA4D1AEFF2D611F0D375F0AD2D" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SeaSpineInc.Member" xlink:label="loc_iart_SeaSpineInc.Member_16F8FFD7533DC5088761F0D375F04AD3" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_582A5EAA4D1AEFF2D611F0D375F0AD2D" xlink:to="loc_iart_SeaSpineInc.Member_16F8FFD7533DC5088761F0D375F04AD3" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="loc_us-gaap_DisposalGroupClassificationAxis_3A2B193511F56E21BC33F0D375F1EB3B" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_D15763A6507519A63173F0D375F0AAB8" xlink:to="loc_us-gaap_DisposalGroupClassificationAxis_3A2B193511F56E21BC33F0D375F1EB3B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="loc_us-gaap_DisposalGroupClassificationDomain_FB781999C46603C1ADF5F0D375F1FAA8" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationAxis_3A2B193511F56E21BC33F0D375F1EB3B" xlink:to="loc_us-gaap_DisposalGroupClassificationDomain_FB781999C46603C1ADF5F0D375F1FAA8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember" xlink:label="loc_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_719F8BCB5D43324F1953F0D375F177F9" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationDomain_FB781999C46603C1ADF5F0D375F1FAA8" xlink:to="loc_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_719F8BCB5D43324F1953F0D375F177F9" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SupplyCommitmentAxis" xlink:label="loc_us-gaap_SupplyCommitmentAxis_A2CEE7670177F237F5ADF0D375F1C033" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_D15763A6507519A63173F0D375F0AAB8" xlink:to="loc_us-gaap_SupplyCommitmentAxis_A2CEE7670177F237F5ADF0D375F1C033" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SupplyCommitmentArrangementMember" xlink:label="loc_us-gaap_SupplyCommitmentArrangementMember_D02F642F6E7206008E89F0D375F1F9F0" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplyCommitmentAxis_A2CEE7670177F237F5ADF0D375F1C033" xlink:to="loc_us-gaap_SupplyCommitmentArrangementMember_D02F642F6E7206008E89F0D375F1F9F0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SupplyCommitmentMember" xlink:label="loc_us-gaap_SupplyCommitmentMember_3380B33827F789027BC1F0D375F100E0" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplyCommitmentArrangementMember_D02F642F6E7206008E89F0D375F1F9F0" xlink:to="loc_us-gaap_SupplyCommitmentMember_3380B33827F789027BC1F0D375F100E0" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_InformationTechnologyandAdministrativeSupportMember" xlink:label="loc_iart_InformationTechnologyandAdministrativeSupportMember_5CCE5FC079227B798BCDF0D375F1C4B8" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplyCommitmentArrangementMember_D02F642F6E7206008E89F0D375F1F9F0" xlink:to="loc_iart_InformationTechnologyandAdministrativeSupportMember_5CCE5FC079227B798BCDF0D375F1C4B8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_109CCC6C77884C0C0D2AF0D375F15AF4" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_D15763A6507519A63173F0D375F0AAB8" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_109CCC6C77884C0C0D2AF0D375F15AF4" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DisposalGroupIncludingDiscontinuedOperationDistributionofSpinoffSharesPercent" xlink:label="loc_iart_DisposalGroupIncludingDiscontinuedOperationDistributionofSpinoffSharesPercent_CB86993A9188897C0A08F0D375F12F7F" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_109CCC6C77884C0C0D2AF0D375F15AF4" xlink:to="loc_iart_DisposalGroupIncludingDiscontinuedOperationDistributionofSpinoffSharesPercent_CB86993A9188897C0A08F0D375F12F7F" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DisposalGroupIncludingDiscontinuedOperationSharesRequiredforIssuanceofSpinoffShare" xlink:label="loc_iart_DisposalGroupIncludingDiscontinuedOperationSharesRequiredforIssuanceofSpinoffShare_15ABBECBCF2384595273F0D375F118FE" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_109CCC6C77884C0C0D2AF0D375F15AF4" xlink:to="loc_iart_DisposalGroupIncludingDiscontinuedOperationSharesRequiredforIssuanceofSpinoffShare_15ABBECBCF2384595273F0D375F118FE" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_RelatedPartySharedManagementNumberofCommonEmployees" xlink:label="loc_iart_RelatedPartySharedManagementNumberofCommonEmployees_8DF47E985AF6DBBBB188F0D375F137AC" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_109CCC6C77884C0C0D2AF0D375F15AF4" xlink:to="loc_iart_RelatedPartySharedManagementNumberofCommonEmployees_8DF47E985AF6DBBBB188F0D375F137AC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationCashAndCashEquivalents" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationCashAndCashEquivalents_B799C0F202B8CBEAFCE7F0D375F1DBDC" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_109CCC6C77884C0C0D2AF0D375F15AF4" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationCashAndCashEquivalents_B799C0F202B8CBEAFCE7F0D375F1DBDC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DiscontinuedOperationGainLossOnDisposalOfDiscontinuedOperationNetOfTax" xlink:label="loc_us-gaap_DiscontinuedOperationGainLossOnDisposalOfDiscontinuedOperationNetOfTax_218D07573DAEDB92415FF0D375F1709B" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_109CCC6C77884C0C0D2AF0D375F15AF4" xlink:to="loc_us-gaap_DiscontinuedOperationGainLossOnDisposalOfDiscontinuedOperationNetOfTax_218D07573DAEDB92415FF0D375F1709B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_A88466E471865004A201F0D375F1DA43" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_109CCC6C77884C0C0D2AF0D375F15AF4" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_A88466E471865004A201F0D375F1DA43" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DiscontinuedOperationIntraEntityAmountsDiscontinuedOperationAfterDisposalRevenue" xlink:label="loc_us-gaap_DiscontinuedOperationIntraEntityAmountsDiscontinuedOperationAfterDisposalRevenue_0D7E78AA145899FB2EB3F0D375F16C67" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_109CCC6C77884C0C0D2AF0D375F15AF4" xlink:to="loc_us-gaap_DiscontinuedOperationIntraEntityAmountsDiscontinuedOperationAfterDisposalRevenue_0D7E78AA145899FB2EB3F0D375F16C67" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DiscontinuedOperationIntraEntityAmountsDiscontinuedOperationAfterDisposalExpense" xlink:label="loc_us-gaap_DiscontinuedOperationIntraEntityAmountsDiscontinuedOperationAfterDisposalExpense_D2312EAFDA254E820E24F0D375F1881C" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_109CCC6C77884C0C0D2AF0D375F15AF4" xlink:to="loc_us-gaap_DiscontinuedOperationIntraEntityAmountsDiscontinuedOperationAfterDisposalExpense_D2312EAFDA254E820E24F0D375F1881C" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/DiscontinuedOperationsSummaryOfAssetsAndLiabilitiesDiscontinuedOperationsDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_7B6DFB5C3F53D893610014FD096D91AD" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_70274EEC1655B7FC508A14FD096D9B2E" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_7B6DFB5C3F53D893610014FD096D91AD" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_70274EEC1655B7FC508A14FD096D9B2E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_E740E6FA852C809F55D914FD096D87DA" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_70274EEC1655B7FC508A14FD096D9B2E" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_E740E6FA852C809F55D914FD096D87DA" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_5037DEE638E7F2FAF51A14FD096D3BB1" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_E740E6FA852C809F55D914FD096D87DA" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_5037DEE638E7F2FAF51A14FD096D3BB1" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SeaSpineInc.Member" xlink:label="loc_iart_SeaSpineInc.Member_C5DA2CDBF9BA3157151914FD096DA714" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_5037DEE638E7F2FAF51A14FD096D3BB1" xlink:to="loc_iart_SeaSpineInc.Member_C5DA2CDBF9BA3157151914FD096DA714" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="loc_us-gaap_DisposalGroupClassificationAxis_F01C56E47E42CBB2A6A314FD096DF624" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_70274EEC1655B7FC508A14FD096D9B2E" xlink:to="loc_us-gaap_DisposalGroupClassificationAxis_F01C56E47E42CBB2A6A314FD096DF624" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="loc_us-gaap_DisposalGroupClassificationDomain_C5FBDA9683D135A8F99814FD096D718B" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationAxis_F01C56E47E42CBB2A6A314FD096DF624" xlink:to="loc_us-gaap_DisposalGroupClassificationDomain_C5FBDA9683D135A8F99814FD096D718B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember" xlink:label="loc_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_9C10F22D0A9D5287FF3614FD096DE14B" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationDomain_C5FBDA9683D135A8F99814FD096D718B" xlink:to="loc_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_9C10F22D0A9D5287FF3614FD096DE14B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_17BB00B977B7476D40B714FD096DB09B" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_70274EEC1655B7FC508A14FD096D9B2E" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_17BB00B977B7476D40B714FD096DB09B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="loc_us-gaap_AssetsAbstract_9D0A8295399C70FD051B14FD096DC02B" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_17BB00B977B7476D40B714FD096DB09B" xlink:to="loc_us-gaap_AssetsAbstract_9D0A8295399C70FD051B14FD096DC02B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrentAbstract" xlink:label="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrentAbstract_149E5FB88F57FB3F5B1214FD096D297D" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_9D0A8295399C70FD051B14FD096DC02B" xlink:to="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrentAbstract_149E5FB88F57FB3F5B1214FD096D297D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationCashAndCashEquivalents" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationCashAndCashEquivalents_14611425F1FFE114D0E414FD096DB07D" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrentAbstract_149E5FB88F57FB3F5B1214FD096D297D" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationCashAndCashEquivalents_14611425F1FFE114D0E414FD096DB07D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsNotesAndLoansReceivableNet" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsNotesAndLoansReceivableNet_6CE71FA048365D7A08B314FD096D1064" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrentAbstract_149E5FB88F57FB3F5B1214FD096D297D" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsNotesAndLoansReceivableNet_6CE71FA048365D7A08B314FD096D1064" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationInventoryCurrent" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationInventoryCurrent_29D408DDDEF8597B1D5414FD096DC850" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrentAbstract_149E5FB88F57FB3F5B1214FD096D297D" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationInventoryCurrent_29D408DDDEF8597B1D5414FD096DC850" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherCurrentAssets" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherCurrentAssets_7FA6B8C5B5816F3FF1B214FD096D989E" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrentAbstract_149E5FB88F57FB3F5B1214FD096D297D" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherCurrentAssets_7FA6B8C5B5816F3FF1B214FD096D989E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrent" xlink:label="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrent_1962E64A33326915404C14FD096DD226" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrentAbstract_149E5FB88F57FB3F5B1214FD096D297D" xlink:to="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrent_1962E64A33326915404C14FD096DD226" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationNoncurrentAbstract" xlink:label="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationNoncurrentAbstract_BD061A95EC56AF68ABF214FD096DE050" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_9D0A8295399C70FD051B14FD096DC02B" xlink:to="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationNoncurrentAbstract_BD061A95EC56AF68ABF214FD096DE050" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationPropertyPlantAndEquipmentNoncurrent" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationPropertyPlantAndEquipmentNoncurrent_C4D9A5000D039D6494D714FD096DBF96" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationNoncurrentAbstract_BD061A95EC56AF68ABF214FD096DE050" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationPropertyPlantAndEquipmentNoncurrent_C4D9A5000D039D6494D714FD096DBF96" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationIntangibleAssetsNoncurrent" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationIntangibleAssetsNoncurrent_E2D79CADF03F4748893C14FD096DF14A" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationNoncurrentAbstract_BD061A95EC56AF68ABF214FD096DE050" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationIntangibleAssetsNoncurrent_E2D79CADF03F4748893C14FD096DF14A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherNoncurrentAssets" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherNoncurrentAssets_EC390741B496C4E9850E14FD096D45AE" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationNoncurrentAbstract_BD061A95EC56AF68ABF214FD096DE050" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherNoncurrentAssets_EC390741B496C4E9850E14FD096D45AE" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationAssetsNoncurrent" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationAssetsNoncurrent_1BEB23B530F3B64C83EC14FD096DB955" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationNoncurrentAbstract_BD061A95EC56AF68ABF214FD096DE050" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationAssetsNoncurrent_1BEB23B530F3B64C83EC14FD096DB955" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperation" xlink:label="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperation_1CB168F2DF78C8F4D5A314FD096D7809" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_9D0A8295399C70FD051B14FD096DC02B" xlink:to="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperation_1CB168F2DF78C8F4D5A314FD096D7809" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LiabilitiesAbstract" xlink:label="loc_us-gaap_LiabilitiesAbstract_5F7B7336697C4099385814FD096D8C71" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_17BB00B977B7476D40B714FD096DB09B" xlink:to="loc_us-gaap_LiabilitiesAbstract_5F7B7336697C4099385814FD096D8C71" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrentAbstract" xlink:label="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrentAbstract_73452529807B5E977ABF14FD096D7F98" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAbstract_5F7B7336697C4099385814FD096D8C71" xlink:to="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrentAbstract_73452529807B5E977ABF14FD096D7F98" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableCurrent" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableCurrent_EC2E84F018F4E1F9A92214FD096D3C7A" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrentAbstract_73452529807B5E977ABF14FD096D7F98" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationAccountsPayableCurrent_EC2E84F018F4E1F9A92214FD096D3C7A" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DisposalGroupIncludingDiscontinuedOperationAccruedCompensationCurrent" xlink:label="loc_iart_DisposalGroupIncludingDiscontinuedOperationAccruedCompensationCurrent_930F7225E2C0042B82B814FD096D9926" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrentAbstract_73452529807B5E977ABF14FD096D7F98" xlink:to="loc_iart_DisposalGroupIncludingDiscontinuedOperationAccruedCompensationCurrent_930F7225E2C0042B82B814FD096D9926" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherCurrentLiabilities" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherCurrentLiabilities_5D42563DA13BF9B12F8514FD096DF6A5" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrentAbstract_73452529807B5E977ABF14FD096D7F98" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherCurrentLiabilities_5D42563DA13BF9B12F8514FD096DF6A5" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrent" xlink:label="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrent_2F4F8AF6CD9E96C0206B14FD096D55C1" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrentAbstract_73452529807B5E977ABF14FD096D7F98" xlink:to="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrent_2F4F8AF6CD9E96C0206B14FD096D55C1" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrentAbstract" xlink:label="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrentAbstract_EA11BE356FDF66C5927014FD096DAE33" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAbstract_5F7B7336697C4099385814FD096D8C71" xlink:to="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrentAbstract_EA11BE356FDF66C5927014FD096DAE33" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationDeferredTaxLiabilitiesNoncurrent" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationDeferredTaxLiabilitiesNoncurrent_799BDC8B2B1D0271462714FD096D28A8" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrentAbstract_EA11BE356FDF66C5927014FD096DAE33" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationDeferredTaxLiabilitiesNoncurrent_799BDC8B2B1D0271462714FD096D28A8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherNoncurrentLiabilities" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherNoncurrentLiabilities_7777614C0348D529EECF14FD096D19EE" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrentAbstract_EA11BE356FDF66C5927014FD096DAE33" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherNoncurrentLiabilities_7777614C0348D529EECF14FD096D19EE" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrent" xlink:label="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrent_489A2A05EF48EDEFAF4314FD096D9132" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrentAbstract_EA11BE356FDF66C5927014FD096DAE33" xlink:to="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrent_489A2A05EF48EDEFAF4314FD096D9132" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperation" xlink:label="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperation_4B91B8820CCB04081E2014FD096D120E" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAbstract_5F7B7336697C4099385814FD096D8C71" xlink:to="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperation_4B91B8820CCB04081E2014FD096D120E" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/DiscontinuedOperationsSummaryOfStatementsOfOperationsDiscontinuedOperationsDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_C104DDE17DAA2471345955ED5A27ABB8" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_49DB6957F5575532AFAE55ED5A273336" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_C104DDE17DAA2471345955ED5A27ABB8" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_49DB6957F5575532AFAE55ED5A273336" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_7838EA19749227C88B1455ED5A277530" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_49DB6957F5575532AFAE55ED5A273336" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_7838EA19749227C88B1455ED5A277530" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_ED22519F10EDEB49D4C855ED5A276D84" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_7838EA19749227C88B1455ED5A277530" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_ED22519F10EDEB49D4C855ED5A276D84" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SeaSpineInc.Member" xlink:label="loc_iart_SeaSpineInc.Member_4499541457DCE0A8A4A655ED5A27E484" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_ED22519F10EDEB49D4C855ED5A276D84" xlink:to="loc_iart_SeaSpineInc.Member_4499541457DCE0A8A4A655ED5A27E484" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="loc_us-gaap_DisposalGroupClassificationAxis_299A6D8C86CBE708A1B755ED5A27C062" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_49DB6957F5575532AFAE55ED5A273336" xlink:to="loc_us-gaap_DisposalGroupClassificationAxis_299A6D8C86CBE708A1B755ED5A27C062" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="loc_us-gaap_DisposalGroupClassificationDomain_969AA3AF82DA44C3464855ED5A27EDDA" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationAxis_299A6D8C86CBE708A1B755ED5A27C062" xlink:to="loc_us-gaap_DisposalGroupClassificationDomain_969AA3AF82DA44C3464855ED5A27EDDA" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember" xlink:label="loc_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_70163B698EC2EC35507855ED5A273C8C" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationDomain_969AA3AF82DA44C3464855ED5A27EDDA" xlink:to="loc_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_70163B698EC2EC35507855ED5A273C8C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_5B30ADC6050404C914E455ED5A2738DB" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_49DB6957F5575532AFAE55ED5A273336" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_5B30ADC6050404C914E455ED5A2738DB" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationRevenue" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationRevenue_699C0167879FBA11D6B455ED5A27452E" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_5B30ADC6050404C914E455ED5A2738DB" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationRevenue_699C0167879FBA11D6B455ED5A27452E" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DisposalGroupIncludingDiscontinuedOperationOperatingExpenseandCostofGoodsSold" xlink:label="loc_iart_DisposalGroupIncludingDiscontinuedOperationOperatingExpenseandCostofGoodsSold_1CF052931ADF0665312055ED5A28DFCF" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_5B30ADC6050404C914E455ED5A2738DB" xlink:to="loc_iart_DisposalGroupIncludingDiscontinuedOperationOperatingExpenseandCostofGoodsSold_1CF052931ADF0665312055ED5A28DFCF" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationOperatingIncomeLoss" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOperatingIncomeLoss_7F1F1409EB7A0BA783B255ED5A28887E" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_5B30ADC6050404C914E455ED5A2738DB" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOperatingIncomeLoss_7F1F1409EB7A0BA783B255ED5A28887E" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DisposalGroupIncludingDiscontinuedOperationOtherIncomeExpenseNet" xlink:label="loc_iart_DisposalGroupIncludingDiscontinuedOperationOtherIncomeExpenseNet_A7E785F08766BB25284655ED5A288790" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_5B30ADC6050404C914E455ED5A2738DB" xlink:to="loc_iart_DisposalGroupIncludingDiscontinuedOperationOtherIncomeExpenseNet_A7E785F08766BB25284655ED5A288790" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax" xlink:label="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax_822AEF031B30DADA048055ED5A28AD15" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_5B30ADC6050404C914E455ED5A2738DB" xlink:to="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax_822AEF031B30DADA048055ED5A28AD15" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DiscontinuedOperationTaxEffectOfDiscontinuedOperation" xlink:label="loc_us-gaap_DiscontinuedOperationTaxEffectOfDiscontinuedOperation_972E39991B6D051A114955ED5A28C381" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_5B30ADC6050404C914E455ED5A2738DB" xlink:to="loc_us-gaap_DiscontinuedOperationTaxEffectOfDiscontinuedOperation_972E39991B6D051A114955ED5A28C381" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_DA45624DCEAE763EB39555ED5A2871F2" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_5B30ADC6050404C914E455ED5A2738DB" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_DA45624DCEAE763EB39555ED5A2871F2" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/DiscontinuedOperationsTables" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_099CC246AE92CA0914EE41CBB952B6FD" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfDisposalGroupsIncludingDiscontinuedOperationsIncomeStatementBalanceSheetAndAdditionalDisclosuresTextBlock" xlink:label="loc_us-gaap_ScheduleOfDisposalGroupsIncludingDiscontinuedOperationsIncomeStatementBalanceSheetAndAdditionalDisclosuresTextBlock_A511BFF58C586CDE577041CBB95282E9" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_099CC246AE92CA0914EE41CBB952B6FD" xlink:to="loc_us-gaap_ScheduleOfDisposalGroupsIncludingDiscontinuedOperationsIncomeStatementBalanceSheetAndAdditionalDisclosuresTextBlock_A511BFF58C586CDE577041CBB95282E9" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/DocumentAndEntityInformation" xlink:type="extended">
    <loc xlink:href="iart-20151231.xsd#iart_DocumentAndEntityInformationAbstract" xlink:label="loc_iart_DocumentAndEntityInformationAbstract_93E9D5B9C8238A40BD772C7085110432" xlink:type="locator" />
    <loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_DocumentType" xlink:label="loc_dei_DocumentType_3CEF44D7DD8F0A193C1B2C708513B0C9" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DocumentAndEntityInformationAbstract_93E9D5B9C8238A40BD772C7085110432" xlink:to="loc_dei_DocumentType_3CEF44D7DD8F0A193C1B2C708513B0C9" xlink:type="arc" />
    <loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_AmendmentFlag" xlink:label="loc_dei_AmendmentFlag_8D714F396CD53397DFDD2C708514E499" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DocumentAndEntityInformationAbstract_93E9D5B9C8238A40BD772C7085110432" xlink:to="loc_dei_AmendmentFlag_8D714F396CD53397DFDD2C708514E499" xlink:type="arc" />
    <loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_DocumentPeriodEndDate" xlink:label="loc_dei_DocumentPeriodEndDate_467CA437496D7433741A2C708514F5D0" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DocumentAndEntityInformationAbstract_93E9D5B9C8238A40BD772C7085110432" xlink:to="loc_dei_DocumentPeriodEndDate_467CA437496D7433741A2C708514F5D0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_DocumentFiscalYearFocus" xlink:label="loc_dei_DocumentFiscalYearFocus_8C9BAEB0D11D2F6ADAAA2C7085145C66" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DocumentAndEntityInformationAbstract_93E9D5B9C8238A40BD772C7085110432" xlink:to="loc_dei_DocumentFiscalYearFocus_8C9BAEB0D11D2F6ADAAA2C7085145C66" xlink:type="arc" />
    <loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_DocumentFiscalPeriodFocus" xlink:label="loc_dei_DocumentFiscalPeriodFocus_176EFD1D45A7308D0E162C70851436BC" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DocumentAndEntityInformationAbstract_93E9D5B9C8238A40BD772C7085110432" xlink:to="loc_dei_DocumentFiscalPeriodFocus_176EFD1D45A7308D0E162C70851436BC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_TradingSymbol" xlink:label="loc_dei_TradingSymbol_1A7E5B0B3D93DD80F7E62C7085140024" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DocumentAndEntityInformationAbstract_93E9D5B9C8238A40BD772C7085110432" xlink:to="loc_dei_TradingSymbol_1A7E5B0B3D93DD80F7E62C7085140024" xlink:type="arc" />
    <loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityRegistrantName" xlink:label="loc_dei_EntityRegistrantName_843144640E313BB940EF2C70851493A6" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DocumentAndEntityInformationAbstract_93E9D5B9C8238A40BD772C7085110432" xlink:to="loc_dei_EntityRegistrantName_843144640E313BB940EF2C70851493A6" xlink:type="arc" />
    <loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityCentralIndexKey" xlink:label="loc_dei_EntityCentralIndexKey_9258805F80D1796FC2F62C70851539AA" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DocumentAndEntityInformationAbstract_93E9D5B9C8238A40BD772C7085110432" xlink:to="loc_dei_EntityCentralIndexKey_9258805F80D1796FC2F62C70851539AA" xlink:type="arc" />
    <loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_CurrentFiscalYearEndDate" xlink:label="loc_dei_CurrentFiscalYearEndDate_5D1F0FD2DA56DABF3C412C7085156A92" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DocumentAndEntityInformationAbstract_93E9D5B9C8238A40BD772C7085110432" xlink:to="loc_dei_CurrentFiscalYearEndDate_5D1F0FD2DA56DABF3C412C7085156A92" xlink:type="arc" />
    <loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityFilerCategory" xlink:label="loc_dei_EntityFilerCategory_844D040821F0752E27C32C7085159FF0" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DocumentAndEntityInformationAbstract_93E9D5B9C8238A40BD772C7085110432" xlink:to="loc_dei_EntityFilerCategory_844D040821F0752E27C32C7085159FF0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityWellKnownSeasonedIssuer" xlink:label="loc_dei_EntityWellKnownSeasonedIssuer_6F0F3372226FA53B21982C708515AF3D" xlink:type="locator" />
    <presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DocumentAndEntityInformationAbstract_93E9D5B9C8238A40BD772C7085110432" xlink:to="loc_dei_EntityWellKnownSeasonedIssuer_6F0F3372226FA53B21982C708515AF3D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityVoluntaryFilers" xlink:label="loc_dei_EntityVoluntaryFilers_68347C3157CA0B40DE852C708515E394" xlink:type="locator" />
    <presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DocumentAndEntityInformationAbstract_93E9D5B9C8238A40BD772C7085110432" xlink:to="loc_dei_EntityVoluntaryFilers_68347C3157CA0B40DE852C708515E394" xlink:type="arc" />
    <loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityCurrentReportingStatus" xlink:label="loc_dei_EntityCurrentReportingStatus_B24D06CE0AF7B0DE35C02C708515132E" xlink:type="locator" />
    <presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DocumentAndEntityInformationAbstract_93E9D5B9C8238A40BD772C7085110432" xlink:to="loc_dei_EntityCurrentReportingStatus_B24D06CE0AF7B0DE35C02C708515132E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityPublicFloat" xlink:label="loc_dei_EntityPublicFloat_0BA25ABB965D1118C01B2C7085151067" xlink:type="locator" />
    <presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DocumentAndEntityInformationAbstract_93E9D5B9C8238A40BD772C7085110432" xlink:to="loc_dei_EntityPublicFloat_0BA25ABB965D1118C01B2C7085151067" xlink:type="arc" />
    <loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityCommonStockSharesOutstanding" xlink:label="loc_dei_EntityCommonStockSharesOutstanding_7FEEE210F784118859BC2C7085151382" xlink:type="locator" />
    <presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DocumentAndEntityInformationAbstract_93E9D5B9C8238A40BD772C7085110432" xlink:to="loc_dei_EntityCommonStockSharesOutstanding_7FEEE210F784118859BC2C7085151382" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/IncomeTaxes" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_8E0CFFEA52AEEA7DAA0B55ED586ADF85" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxDisclosureTextBlock" xlink:label="loc_us-gaap_IncomeTaxDisclosureTextBlock_AA208D002627EBE34CB355ED586A22AB" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_8E0CFFEA52AEEA7DAA0B55ED586ADF85" xlink:to="loc_us-gaap_IncomeTaxDisclosureTextBlock_AA208D002627EBE34CB355ED586A22AB" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/IncomeTaxesNarrativeDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_9230DDEA5F66DE9BD06D1977034932FC" xlink:type="locator" />
    <loc xlink:href="iart-20151231.xsd#iart_IncomeTaxTable" xlink:label="loc_iart_IncomeTaxTable_5E57CDB7003E0A4BFEF319770349DA62" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_9230DDEA5F66DE9BD06D1977034932FC" xlink:to="loc_iart_IncomeTaxTable_5E57CDB7003E0A4BFEF319770349DA62" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxAuthorityAxis" xlink:label="loc_us-gaap_IncomeTaxAuthorityAxis_62192E959DFF62E1526F19770349A0B2" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxTable_5E57CDB7003E0A4BFEF319770349DA62" xlink:to="loc_us-gaap_IncomeTaxAuthorityAxis_62192E959DFF62E1526F19770349A0B2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxAuthorityDomain" xlink:label="loc_us-gaap_IncomeTaxAuthorityDomain_4B544254A97EC75DC17219770349124C" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityAxis_62192E959DFF62E1526F19770349A0B2" xlink:to="loc_us-gaap_IncomeTaxAuthorityDomain_4B544254A97EC75DC17219770349124C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InternalRevenueServiceIRSMember" xlink:label="loc_us-gaap_InternalRevenueServiceIRSMember_3EE632579853D56E19E6197703496A11" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityDomain_4B544254A97EC75DC17219770349124C" xlink:to="loc_us-gaap_InternalRevenueServiceIRSMember_3EE632579853D56E19E6197703496A11" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ForeignCountryMember" xlink:label="loc_us-gaap_ForeignCountryMember_687AA4917D7899E99FBD1977034995A5" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityDomain_4B544254A97EC75DC17219770349124C" xlink:to="loc_us-gaap_ForeignCountryMember_687AA4917D7899E99FBD1977034995A5" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StateAndLocalJurisdictionMember" xlink:label="loc_us-gaap_StateAndLocalJurisdictionMember_D87100CE4376025B73EA19770349A6DB" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityDomain_4B544254A97EC75DC17219770349124C" xlink:to="loc_us-gaap_StateAndLocalJurisdictionMember_D87100CE4376025B73EA19770349A6DB" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_IncomeTaxLineItems" xlink:label="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxTable_5E57CDB7003E0A4BFEF319770349DA62" xlink:to="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_EffectiveIncomeTaxRateReconciliationIncreaseDecreaseDuringPeriodPercent" xlink:label="loc_iart_EffectiveIncomeTaxRateReconciliationIncreaseDecreaseDuringPeriodPercent_3211F7D85906C1999CA719770349C9A7" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:to="loc_iart_EffectiveIncomeTaxRateReconciliationIncreaseDecreaseDuringPeriodPercent_3211F7D85906C1999CA719770349C9A7" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_IncreaseDecreasetoUncertainTaxAccrual" xlink:label="loc_iart_IncreaseDecreasetoUncertainTaxAccrual_4217DCC1AFB67187456019770349B659" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:to="loc_iart_IncreaseDecreasetoUncertainTaxAccrual_4217DCC1AFB67187456019770349B659" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential" xlink:label="loc_us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential_EC7B3EEAA576E8362B94197703492C5E" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:to="loc_us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential_EC7B3EEAA576E8362B94197703492C5E" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_EffectiveForeignIncomeTaxRateReconciliationContinuingOperations" xlink:label="loc_iart_EffectiveForeignIncomeTaxRateReconciliationContinuingOperations_E54E5102A3040234BD841977034955B8" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:to="loc_iart_EffectiveForeignIncomeTaxRateReconciliationContinuingOperations_E54E5102A3040234BD841977034955B8" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_EffectiveForeignIncomeTaxRateReconciliationIncreaseDecreaseDuringPeriodPercent" xlink:label="loc_iart_EffectiveForeignIncomeTaxRateReconciliationIncreaseDecreaseDuringPeriodPercent_FFEA65A3A5E266D87BC3197703496BF6" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:to="loc_iart_EffectiveForeignIncomeTaxRateReconciliationIncreaseDecreaseDuringPeriodPercent_FFEA65A3A5E266D87BC3197703496BF6" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxReconciliationRepatriationOfForeignEarnings" xlink:label="loc_us-gaap_IncomeTaxReconciliationRepatriationOfForeignEarnings_83F17BF19CA4D815507E19770349C255" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:to="loc_us-gaap_IncomeTaxReconciliationRepatriationOfForeignEarnings_83F17BF19CA4D815507E19770349C255" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_UndistributedEarningsOfForeignSubsidiaries" xlink:label="loc_us-gaap_UndistributedEarningsOfForeignSubsidiaries_DB323E8A4A2A287EF1AF197703499986" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:to="loc_us-gaap_UndistributedEarningsOfForeignSubsidiaries_DB323E8A4A2A287EF1AF197703499986" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_EstimatedTaxLiabilityonUndistributedEarningsofForeignSubsidiaries" xlink:label="loc_iart_EstimatedTaxLiabilityonUndistributedEarningsofForeignSubsidiaries_31EE026736237F0E8D431977034A8E97" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:to="loc_iart_EstimatedTaxLiabilityonUndistributedEarningsofForeignSubsidiaries_31EE026736237F0E8D431977034A8E97" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OperatingLossCarryforwards" xlink:label="loc_us-gaap_OperatingLossCarryforwards_1535D360AF454AF5754F1977034AF810" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:to="loc_us-gaap_OperatingLossCarryforwards_1535D360AF454AF5754F1977034AF810" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsSubjectToExpiration" xlink:label="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsSubjectToExpiration_1A23057C28B420865CEC1977034A0F48" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:to="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsSubjectToExpiration_1A23057C28B420865CEC1977034A0F48" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsNotSubjectToExpiration" xlink:label="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsNotSubjectToExpiration_C4DCC73A0CB53DC6B2241977034A3385" xlink:type="locator" />
    <presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:to="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsNotSubjectToExpiration_C4DCC73A0CB53DC6B2241977034A3385" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxAssetsValuationAllowance" xlink:label="loc_us-gaap_DeferredTaxAssetsValuationAllowance_D258BBCBB88C9F625B341977034A133E" xlink:type="locator" />
    <presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:to="loc_us-gaap_DeferredTaxAssetsValuationAllowance_D258BBCBB88C9F625B341977034A133E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxAssetsGross" xlink:label="loc_us-gaap_DeferredTaxAssetsGross_7558100EA7494668A84E1977034A5BC7" xlink:type="locator" />
    <presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:to="loc_us-gaap_DeferredTaxAssetsGross_7558100EA7494668A84E1977034A5BC7" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ValuationAllowancesAndReservesPeriodIncreaseDecrease" xlink:label="loc_us-gaap_ValuationAllowancesAndReservesPeriodIncreaseDecrease_AC8BECC9656F25B340C81977034A114C" xlink:type="locator" />
    <presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:to="loc_us-gaap_ValuationAllowancesAndReservesPeriodIncreaseDecrease_AC8BECC9656F25B340C81977034A114C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate_590135F79634EE4A1B9C1977034A5C83" xlink:type="locator" />
    <presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate_590135F79634EE4A1B9C1977034A5C83" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SignificantChangeInUnrecognizedTaxBenefitsIsReasonablyPossibleAmountOfUnrecordedBenefit" xlink:label="loc_us-gaap_SignificantChangeInUnrecognizedTaxBenefitsIsReasonablyPossibleAmountOfUnrecordedBenefit_3971D36CBF36CC2DEE921977034A4B50" xlink:type="locator" />
    <presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:to="loc_us-gaap_SignificantChangeInUnrecognizedTaxBenefitsIsReasonablyPossibleAmountOfUnrecordedBenefit_3971D36CBF36CC2DEE921977034A4B50" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense_A15011F4EE12D1CD77111977034AF523" xlink:type="locator" />
    <presentationArc order="17" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense_A15011F4EE12D1CD77111977034AF523" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxExaminationPenaltiesAndInterestAccrued" xlink:label="loc_us-gaap_IncomeTaxExaminationPenaltiesAndInterestAccrued_6F67F98426920F521AA11977034A2299" xlink:type="locator" />
    <presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_IncomeTaxLineItems_FDC9F2A21A3A1C8A4B6919770349F443" xlink:to="loc_us-gaap_IncomeTaxExaminationPenaltiesAndInterestAccrued_6F67F98426920F521AA11977034A2299" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/IncomeTaxesScheduleOfDeferredTaxAssetsAndLiabilitiesDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_8330C14863962BB31FE61F4A4A62D215" xlink:type="locator" />
    <loc xlink:href="iart-20151231.xsd#iart_DeferredTaxAssetsCurrentClassificationAbstract" xlink:label="loc_iart_DeferredTaxAssetsCurrentClassificationAbstract_665D32D28A654325B4171F4A4A6294F6" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_8330C14863962BB31FE61F4A4A62D215" xlink:to="loc_iart_DeferredTaxAssetsCurrentClassificationAbstract_665D32D28A654325B4171F4A4A6294F6" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAllowanceForDoubtfulAccounts" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAllowanceForDoubtfulAccounts_2FC916BAF42CC84EC3D01F4A4A62A388" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsCurrentClassificationAbstract_665D32D28A654325B4171F4A4A6294F6" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAllowanceForDoubtfulAccounts_2FC916BAF42CC84EC3D01F4A4A62A388" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxAssetsInventory" xlink:label="loc_us-gaap_DeferredTaxAssetsInventory_754105FBF9A6408A443F1F4A4A6336A8" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsCurrentClassificationAbstract_665D32D28A654325B4171F4A4A6294F6" xlink:to="loc_us-gaap_DeferredTaxAssetsInventory_754105FBF9A6408A443F1F4A4A6336A8" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DeferredTaxAssetsTaxCreditCarryforwardsCurrent" xlink:label="loc_iart_DeferredTaxAssetsTaxCreditCarryforwardsCurrent_D5A90F940BFAC111D10A1F4A4A63002C" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsCurrentClassificationAbstract_665D32D28A654325B4171F4A4A6294F6" xlink:to="loc_iart_DeferredTaxAssetsTaxCreditCarryforwardsCurrent_D5A90F940BFAC111D10A1F4A4A63002C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsCompensatedAbsences" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsCompensatedAbsences_BB714528CD7B7D6CE3DE1F4A4A631328" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsCurrentClassificationAbstract_665D32D28A654325B4171F4A4A6294F6" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsCompensatedAbsences_BB714528CD7B7D6CE3DE1F4A4A631328" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsEmployeeBonuses" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsEmployeeBonuses_36938C3CA9A0EC8DD73B1F4A4A63A608" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsCurrentClassificationAbstract_665D32D28A654325B4171F4A4A6294F6" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsEmployeeBonuses_36938C3CA9A0EC8DD73B1F4A4A63A608" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DeferredTaxAssetsOtherCurrent" xlink:label="loc_iart_DeferredTaxAssetsOtherCurrent_B353A64C614EA17E2D271F4A4A63E3C9" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsCurrentClassificationAbstract_665D32D28A654325B4171F4A4A6294F6" xlink:to="loc_iart_DeferredTaxAssetsOtherCurrent_B353A64C614EA17E2D271F4A4A63E3C9" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxAssetsGrossCurrent" xlink:label="loc_us-gaap_DeferredTaxAssetsGrossCurrent_AD0F06DF940B879F1B3F1F4A4A6307DF" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsCurrentClassificationAbstract_665D32D28A654325B4171F4A4A6294F6" xlink:to="loc_us-gaap_DeferredTaxAssetsGrossCurrent_AD0F06DF940B879F1B3F1F4A4A6307DF" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxAssetsValuationAllowanceCurrent" xlink:label="loc_us-gaap_DeferredTaxAssetsValuationAllowanceCurrent_E8E8625DFE79B99850901F4A4A63147A" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsCurrentClassificationAbstract_665D32D28A654325B4171F4A4A6294F6" xlink:to="loc_us-gaap_DeferredTaxAssetsValuationAllowanceCurrent_E8E8625DFE79B99850901F4A4A63147A" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_NetDeferredTaxAssetsCurrentAfterValuationAllowance" xlink:label="loc_iart_NetDeferredTaxAssetsCurrentAfterValuationAllowance_7715C82F10E030C84AC91F4A4A632FB5" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsCurrentClassificationAbstract_665D32D28A654325B4171F4A4A6294F6" xlink:to="loc_iart_NetDeferredTaxAssetsCurrentAfterValuationAllowance_7715C82F10E030C84AC91F4A4A632FB5" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DeferredTaxLiabilitiesCurrentClassificationAbstract" xlink:label="loc_iart_DeferredTaxLiabilitiesCurrentClassificationAbstract_7CB6D6D74ECE072F80991F4A4A631B5C" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_8330C14863962BB31FE61F4A4A62D215" xlink:to="loc_iart_DeferredTaxLiabilitiesCurrentClassificationAbstract_7CB6D6D74ECE072F80991F4A4A631B5C" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DeferredTaxLiabilitiesOtherCurrent" xlink:label="loc_iart_DeferredTaxLiabilitiesOtherCurrent_C0275051E8D3C35416C91F4A4A6335B4" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxLiabilitiesCurrentClassificationAbstract_7CB6D6D74ECE072F80991F4A4A631B5C" xlink:to="loc_iart_DeferredTaxLiabilitiesOtherCurrent_C0275051E8D3C35416C91F4A4A6335B4" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxLiabilitiesCurrent" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesCurrent_E3CE8CC68FF010DFD17E1F4A4A63B913" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxLiabilitiesCurrentClassificationAbstract_7CB6D6D74ECE072F80991F4A4A631B5C" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesCurrent_E3CE8CC68FF010DFD17E1F4A4A63B913" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxAssetsLiabilitiesNetCurrent" xlink:label="loc_us-gaap_DeferredTaxAssetsLiabilitiesNetCurrent_5B28AABBCAE543C3ACDC1F4A4A633513" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxLiabilitiesCurrentClassificationAbstract_7CB6D6D74ECE072F80991F4A4A631B5C" xlink:to="loc_us-gaap_DeferredTaxAssetsLiabilitiesNetCurrent_5B28AABBCAE543C3ACDC1F4A4A633513" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DeferredTaxAssetsNoncurrentClassificationAbstract" xlink:label="loc_iart_DeferredTaxAssetsNoncurrentClassificationAbstract_D8B3CB16BF5860729E991F4A4A6395B9" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_8330C14863962BB31FE61F4A4A62D215" xlink:to="loc_iart_DeferredTaxAssetsNoncurrentClassificationAbstract_D8B3CB16BF5860729E991F4A4A6395B9" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DeferredTaxAssetsTaxDeferredExpenseReservesandAccrualsAllowanceforDoubtfulAccountsNoncurrent" xlink:label="loc_iart_DeferredTaxAssetsTaxDeferredExpenseReservesandAccrualsAllowanceforDoubtfulAccountsNoncurrent_0E874383F888C76F92EB1F4A4A63F805" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsNoncurrentClassificationAbstract_D8B3CB16BF5860729E991F4A4A6395B9" xlink:to="loc_iart_DeferredTaxAssetsTaxDeferredExpenseReservesandAccrualsAllowanceforDoubtfulAccountsNoncurrent_0E874383F888C76F92EB1F4A4A63F805" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DeferredTaxAssetsInventoryNoncurrent" xlink:label="loc_iart_DeferredTaxAssetsInventoryNoncurrent_D61392F1010C786737841F4A4A647E5C" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsNoncurrentClassificationAbstract_D8B3CB16BF5860729E991F4A4A6395B9" xlink:to="loc_iart_DeferredTaxAssetsInventoryNoncurrent_D61392F1010C786737841F4A4A647E5C" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DeferredTaxAssetsTaxCreditCarryforwardsNoncurrent" xlink:label="loc_iart_DeferredTaxAssetsTaxCreditCarryforwardsNoncurrent_5A31314D88EEED2828251F4A4A64ED30" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsNoncurrentClassificationAbstract_D8B3CB16BF5860729E991F4A4A6395B9" xlink:to="loc_iart_DeferredTaxAssetsTaxCreditCarryforwardsNoncurrent_5A31314D88EEED2828251F4A4A64ED30" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DeferredTaxAssetsTaxDeferredExpenseCompensationandBenefitsCompensatedAbsencesNoncurrent" xlink:label="loc_iart_DeferredTaxAssetsTaxDeferredExpenseCompensationandBenefitsCompensatedAbsencesNoncurrent_58893AE78DAB148F26301F4A4A647EF3" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsNoncurrentClassificationAbstract_D8B3CB16BF5860729E991F4A4A6395B9" xlink:to="loc_iart_DeferredTaxAssetsTaxDeferredExpenseCompensationandBenefitsCompensatedAbsencesNoncurrent_58893AE78DAB148F26301F4A4A647EF3" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DeferredTaxAssetsTaxDeferredExpenseCompensationandBenefitsEmployeeBonusesNoncurrent" xlink:label="loc_iart_DeferredTaxAssetsTaxDeferredExpenseCompensationandBenefitsEmployeeBonusesNoncurrent_D064D3DD118813715C581F4A4A644CC1" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsNoncurrentClassificationAbstract_D8B3CB16BF5860729E991F4A4A6395B9" xlink:to="loc_iart_DeferredTaxAssetsTaxDeferredExpenseCompensationandBenefitsEmployeeBonusesNoncurrent_D064D3DD118813715C581F4A4A644CC1" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_5B36C2A7DD0E0BAAF2CC1F4A4A644591" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsNoncurrentClassificationAbstract_D8B3CB16BF5860729E991F4A4A6395B9" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_5B36C2A7DD0E0BAAF2CC1F4A4A644591" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxAssetsDeferredIncome" xlink:label="loc_us-gaap_DeferredTaxAssetsDeferredIncome_90EECAF943536EDDE0611F4A4A649231" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsNoncurrentClassificationAbstract_D8B3CB16BF5860729E991F4A4A6395B9" xlink:to="loc_us-gaap_DeferredTaxAssetsDeferredIncome_90EECAF943536EDDE0611F4A4A649231" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwards" xlink:label="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_0D75AF7863004E0CCBDF1F4A4A648E60" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsNoncurrentClassificationAbstract_D8B3CB16BF5860729E991F4A4A6395B9" xlink:to="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_0D75AF7863004E0CCBDF1F4A4A648E60" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DeferredTaxAssetsFederalandStateTaxCreditCarryforwardsNoncurrent" xlink:label="loc_iart_DeferredTaxAssetsFederalandStateTaxCreditCarryforwardsNoncurrent_95F53B17ABE3481E2DF51F4A4A6430AC" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsNoncurrentClassificationAbstract_D8B3CB16BF5860729E991F4A4A6395B9" xlink:to="loc_iart_DeferredTaxAssetsFederalandStateTaxCreditCarryforwardsNoncurrent_95F53B17ABE3481E2DF51F4A4A6430AC" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DeferredTaxAssetsOtherNoncurrent" xlink:label="loc_iart_DeferredTaxAssetsOtherNoncurrent_40A5834A0E5FD51DF1BE1F4A4A6431F4" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsNoncurrentClassificationAbstract_D8B3CB16BF5860729E991F4A4A6395B9" xlink:to="loc_iart_DeferredTaxAssetsOtherNoncurrent_40A5834A0E5FD51DF1BE1F4A4A6431F4" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxAssetsGrossNoncurrent" xlink:label="loc_us-gaap_DeferredTaxAssetsGrossNoncurrent_5AF8548FF936FE9211D71F4A4A64AC88" xlink:type="locator" />
    <presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsNoncurrentClassificationAbstract_D8B3CB16BF5860729E991F4A4A6395B9" xlink:to="loc_us-gaap_DeferredTaxAssetsGrossNoncurrent_5AF8548FF936FE9211D71F4A4A64AC88" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxAssetsValuationAllowanceNoncurrent" xlink:label="loc_us-gaap_DeferredTaxAssetsValuationAllowanceNoncurrent_4FF53EBCFD4A52C70DB51F4A4A644CE6" xlink:type="locator" />
    <presentationArc order="12" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsNoncurrentClassificationAbstract_D8B3CB16BF5860729E991F4A4A6395B9" xlink:to="loc_us-gaap_DeferredTaxAssetsValuationAllowanceNoncurrent_4FF53EBCFD4A52C70DB51F4A4A644CE6" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_NetDeferredTaxAssetsNoncurrentAfterValuationAllowance" xlink:label="loc_iart_NetDeferredTaxAssetsNoncurrentAfterValuationAllowance_D44AEA3A9D17F1B03EE51F4A4A642488" xlink:type="locator" />
    <presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxAssetsNoncurrentClassificationAbstract_D8B3CB16BF5860729E991F4A4A6395B9" xlink:to="loc_iart_NetDeferredTaxAssetsNoncurrentAfterValuationAllowance_D44AEA3A9D17F1B03EE51F4A4A642488" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DeferredTaxLiabilitiesNoncurrentClassificationAbstract" xlink:label="loc_iart_DeferredTaxLiabilitiesNoncurrentClassificationAbstract_62DE53B8947D47B625331F4A4A640D4A" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_8330C14863962BB31FE61F4A4A62D215" xlink:to="loc_iart_DeferredTaxLiabilitiesNoncurrentClassificationAbstract_62DE53B8947D47B625331F4A4A640D4A" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DeferredTaxLiabilitiesGoodwillandIntangibleAssetsIntangibleandFixedAssets" xlink:label="loc_iart_DeferredTaxLiabilitiesGoodwillandIntangibleAssetsIntangibleandFixedAssets_99F700B1F561DDD9F94B1F4A4A645806" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxLiabilitiesNoncurrentClassificationAbstract_62DE53B8947D47B625331F4A4A640D4A" xlink:to="loc_iart_DeferredTaxLiabilitiesGoodwillandIntangibleAssetsIntangibleandFixedAssets_99F700B1F561DDD9F94B1F4A4A645806" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DeferredTaxLiabilitiesOtherNoncurrent" xlink:label="loc_iart_DeferredTaxLiabilitiesOtherNoncurrent_CFC8D7BCF16FD02027CB1F4A4A65AA40" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxLiabilitiesNoncurrentClassificationAbstract_62DE53B8947D47B625331F4A4A640D4A" xlink:to="loc_iart_DeferredTaxLiabilitiesOtherNoncurrent_CFC8D7BCF16FD02027CB1F4A4A65AA40" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DeferredTaxLiabilitiesNetNoncurrent" xlink:label="loc_iart_DeferredTaxLiabilitiesNetNoncurrent_39CF387976FD0C52AD581F4A4A651631" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_DeferredTaxLiabilitiesNoncurrentClassificationAbstract_62DE53B8947D47B625331F4A4A640D4A" xlink:to="loc_iart_DeferredTaxLiabilitiesNetNoncurrent_39CF387976FD0C52AD581F4A4A651631" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxAssetsLiabilitiesNetNoncurrent" xlink:label="loc_us-gaap_DeferredTaxAssetsLiabilitiesNetNoncurrent_DA2DABDCED085AD153A21F4A4A65360A" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_8330C14863962BB31FE61F4A4A62D215" xlink:to="loc_us-gaap_DeferredTaxAssetsLiabilitiesNetNoncurrent_DA2DABDCED085AD153A21F4A4A65360A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxLiabilities" xlink:label="loc_us-gaap_DeferredTaxLiabilities_D220C1146D93FD50BEA21F4A4A65CC01" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_8330C14863962BB31FE61F4A4A62D215" xlink:to="loc_us-gaap_DeferredTaxLiabilities_D220C1146D93FD50BEA21F4A4A65CC01" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/IncomeTaxesScheduleOfEffectiveTaxRateReconciliationDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_727267F30C4677BCBD201F225F0179B9" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate_6EC793BB6BC6A1DB09EF1F225F01AC67" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_727267F30C4677BCBD201F225F0179B9" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate_6EC793BB6BC6A1DB09EF1F225F01AC67" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_EC4CDF25613F564A57F71F225F03B44A" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_727267F30C4677BCBD201F225F0179B9" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_EC4CDF25613F564A57F71F225F03B44A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes_64F2C83BE61AD6D1A25E1F225F031DDA" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_EC4CDF25613F564A57F71F225F03B44A" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes_64F2C83BE61AD6D1A25E1F225F031DDA" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential_0D863B366EE1EB3DB8D71F225F03582F" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_EC4CDF25613F564A57F71F225F03B44A" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential_0D863B366EE1EB3DB8D71F225F03582F" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_EffectiveIncomeTaxRateReconciliationChangeinDeferredTaxAssetsValuationAllowanceDuetoAcquisitionPercent" xlink:label="loc_iart_EffectiveIncomeTaxRateReconciliationChangeinDeferredTaxAssetsValuationAllowanceDuetoAcquisitionPercent_067EA9DEC1E68AD8FACB1F225F03329D" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_EC4CDF25613F564A57F71F225F03B44A" xlink:to="loc_iart_EffectiveIncomeTaxRateReconciliationChangeinDeferredTaxAssetsValuationAllowanceDuetoAcquisitionPercent_067EA9DEC1E68AD8FACB1F225F03329D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseCharitableContributions" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseCharitableContributions_7A9BE1EA3D69575FB69D1F225F0374B1" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_EC4CDF25613F564A57F71F225F03B44A" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseCharitableContributions_7A9BE1EA3D69575FB69D1F225F0374B1" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationDeductionsQualifiedProductionActivities" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationDeductionsQualifiedProductionActivities_2BCF9BB0D6C35897515C1F225F034C6B" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_EC4CDF25613F564A57F71F225F03B44A" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationDeductionsQualifiedProductionActivities_2BCF9BB0D6C35897515C1F225F034C6B" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_EffectiveIncomeTaxRateReconciliationDeductionIntercompanyInventoryPercent" xlink:label="loc_iart_EffectiveIncomeTaxRateReconciliationDeductionIntercompanyInventoryPercent_7253262FDEA4F84EFB101F225F0325F6" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_EC4CDF25613F564A57F71F225F03B44A" xlink:to="loc_iart_EffectiveIncomeTaxRateReconciliationDeductionIntercompanyInventoryPercent_7253262FDEA4F84EFB101F225F0325F6" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseLegalandProfessionalPercent" xlink:label="loc_iart_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseLegalandProfessionalPercent_BF77B27AAAAA455A7D131F225F03F5C2" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_EC4CDF25613F564A57F71F225F03B44A" xlink:to="loc_iart_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseLegalandProfessionalPercent_BF77B27AAAAA455A7D131F225F03F5C2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance_4B73D7E937552D29FDF01F225F034A80" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_EC4CDF25613F564A57F71F225F03B44A" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance_4B73D7E937552D29FDF01F225F034A80" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationTaxContingenciesOther" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationTaxContingenciesOther_69975AE1193C5DD7D4341F225F03CFEC" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_EC4CDF25613F564A57F71F225F03B44A" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationTaxContingenciesOther_69975AE1193C5DD7D4341F225F03CFEC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationTaxCreditsResearch" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationTaxCreditsResearch_B1C438566C065CA10D791F225F030A23" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_EC4CDF25613F564A57F71F225F03B44A" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationTaxCreditsResearch_B1C438566C065CA10D791F225F030A23" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationPriorYearIncomeTaxes" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationPriorYearIncomeTaxes_F78B85DA12B9AB60A8F61F225F031472" xlink:type="locator" />
    <presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_EC4CDF25613F564A57F71F225F03B44A" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationPriorYearIncomeTaxes_F78B85DA12B9AB60A8F61F225F031472" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments_C99861608D40F43366EA1F225F03BB94" xlink:type="locator" />
    <presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperationsTaxRateReconciliationAbstract_EC4CDF25613F564A57F71F225F03B44A" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments_C99861608D40F43366EA1F225F03BB94" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EffectiveIncomeTaxRateContinuingOperations" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_C38574FD924433CED8681F225F0472F1" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_727267F30C4677BCBD201F225F0179B9" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_C38574FD924433CED8681F225F0472F1" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/IncomeTaxesScheduleOfIncomeBeforeIncomeTaxesDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_259ED4BDD1A247FAAE9922829E2704FC" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic_C19C77F8749A7A05F59B22829E27C121" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_259ED4BDD1A247FAAE9922829E2704FC" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic_C19C77F8749A7A05F59B22829E27C121" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign_4EED05CC0382AD9CCE6722829E280355" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_259ED4BDD1A247FAAE9922829E2704FC" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign_4EED05CC0382AD9CCE6722829E280355" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_522AC43CDB2434BCF5AD22829E285497" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_259ED4BDD1A247FAAE9922829E2704FC" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_522AC43CDB2434BCF5AD22829E285497" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/IncomeTaxesScheduleOfProvisionForIncomeTaxesDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_2377FADBC7E6473099F0227F18EFFCF1" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CurrentIncomeTaxExpenseBenefitContinuingOperationsAbstract" xlink:label="loc_us-gaap_CurrentIncomeTaxExpenseBenefitContinuingOperationsAbstract_7F96A9841D67720C26A4227F18EF731C" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_2377FADBC7E6473099F0227F18EFFCF1" xlink:to="loc_us-gaap_CurrentIncomeTaxExpenseBenefitContinuingOperationsAbstract_7F96A9841D67720C26A4227F18EF731C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CurrentFederalTaxExpenseBenefit" xlink:label="loc_us-gaap_CurrentFederalTaxExpenseBenefit_05877C26A84C3A09ED54227F18EF512A" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CurrentIncomeTaxExpenseBenefitContinuingOperationsAbstract_7F96A9841D67720C26A4227F18EF731C" xlink:to="loc_us-gaap_CurrentFederalTaxExpenseBenefit_05877C26A84C3A09ED54227F18EF512A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CurrentStateAndLocalTaxExpenseBenefit" xlink:label="loc_us-gaap_CurrentStateAndLocalTaxExpenseBenefit_EDF34D8D7D9174F242BB227F18EF1DEF" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CurrentIncomeTaxExpenseBenefitContinuingOperationsAbstract_7F96A9841D67720C26A4227F18EF731C" xlink:to="loc_us-gaap_CurrentStateAndLocalTaxExpenseBenefit_EDF34D8D7D9174F242BB227F18EF1DEF" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CurrentForeignTaxExpenseBenefit" xlink:label="loc_us-gaap_CurrentForeignTaxExpenseBenefit_11D5C5A30B83627C03CB227F18EF33EC" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CurrentIncomeTaxExpenseBenefitContinuingOperationsAbstract_7F96A9841D67720C26A4227F18EF731C" xlink:to="loc_us-gaap_CurrentForeignTaxExpenseBenefit_11D5C5A30B83627C03CB227F18EF33EC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CurrentIncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_C32764BF65150BCBFCB7227F18EFCB68" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CurrentIncomeTaxExpenseBenefitContinuingOperationsAbstract_7F96A9841D67720C26A4227F18EF731C" xlink:to="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_C32764BF65150BCBFCB7227F18EFCB68" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredIncomeTaxExpenseBenefitContinuingOperationsAbstract" xlink:label="loc_us-gaap_DeferredIncomeTaxExpenseBenefitContinuingOperationsAbstract_2F0528B35419186AAB05227F18EFDED0" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_2377FADBC7E6473099F0227F18EFFCF1" xlink:to="loc_us-gaap_DeferredIncomeTaxExpenseBenefitContinuingOperationsAbstract_2F0528B35419186AAB05227F18EFDED0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredFederalIncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_DeferredFederalIncomeTaxExpenseBenefit_5329AFE063E01E26A136227F18F4A3F2" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredIncomeTaxExpenseBenefitContinuingOperationsAbstract_2F0528B35419186AAB05227F18EFDED0" xlink:to="loc_us-gaap_DeferredFederalIncomeTaxExpenseBenefit_5329AFE063E01E26A136227F18F4A3F2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredStateAndLocalIncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_DeferredStateAndLocalIncomeTaxExpenseBenefit_A18713D9A194966F4A15227F18F4A4E5" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredIncomeTaxExpenseBenefitContinuingOperationsAbstract_2F0528B35419186AAB05227F18EFDED0" xlink:to="loc_us-gaap_DeferredStateAndLocalIncomeTaxExpenseBenefit_A18713D9A194966F4A15227F18F4A4E5" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredForeignIncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_DeferredForeignIncomeTaxExpenseBenefit_7934C2DC575F0CF5C4E0227F18F46E9F" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredIncomeTaxExpenseBenefitContinuingOperationsAbstract_2F0528B35419186AAB05227F18EFDED0" xlink:to="loc_us-gaap_DeferredForeignIncomeTaxExpenseBenefit_7934C2DC575F0CF5C4E0227F18F46E9F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_B95A0DA51544D49BC224227F18F41A23" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredIncomeTaxExpenseBenefitContinuingOperationsAbstract_2F0528B35419186AAB05227F18EFDED0" xlink:to="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_B95A0DA51544D49BC224227F18F41A23" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_58C54AFB69A524C4C6B2227F18F5E55C" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_2377FADBC7E6473099F0227F18EFFCF1" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_58C54AFB69A524C4C6B2227F18F5E55C" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/IncomeTaxesScheduleOfUncertainTaxBenefitsReconciliationDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_21505D775212B60F971EFB840C27A76E" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward" xlink:label="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_568FB4FD7324FC809F12FB840C278CB2" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_21505D775212B60F971EFB840C27A76E" xlink:to="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_568FB4FD7324FC809F12FB840C278CB2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_UnrecognizedTaxBenefits" xlink:label="loc_us-gaap_UnrecognizedTaxBenefits_FA9AD1A095B44795FEDCFB840C277D5C" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_568FB4FD7324FC809F12FB840C278CB2" xlink:to="loc_us-gaap_UnrecognizedTaxBenefits_FA9AD1A095B44795FEDCFB840C277D5C" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_UnrecognizedTaxBenefitsIncreasesDuringPeriodAbstract" xlink:label="loc_iart_UnrecognizedTaxBenefitsIncreasesDuringPeriodAbstract_D52620EFCB04E98FFE82FB840C27D849" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_568FB4FD7324FC809F12FB840C278CB2" xlink:to="loc_iart_UnrecognizedTaxBenefitsIncreasesDuringPeriodAbstract_D52620EFCB04E98FFE82FB840C27D849" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions_1EA940364F8F3F676630FB840C27198A" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_UnrecognizedTaxBenefitsIncreasesDuringPeriodAbstract_D52620EFCB04E98FFE82FB840C27D849" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions_1EA940364F8F3F676630FB840C27198A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromPriorPeriodTaxPositions" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromPriorPeriodTaxPositions_1566B80DB866E13E0EA6FB840C270BB9" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_UnrecognizedTaxBenefitsIncreasesDuringPeriodAbstract_D52620EFCB04E98FFE82FB840C27D849" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromPriorPeriodTaxPositions_1566B80DB866E13E0EA6FB840C270BB9" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_UnrecognizedTaxBenefitsDecreasesDuringPeriodAbstract" xlink:label="loc_iart_UnrecognizedTaxBenefitsDecreasesDuringPeriodAbstract_14A7C9E4C5C0F5A70857FB840C2792A3" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_568FB4FD7324FC809F12FB840C278CB2" xlink:to="loc_iart_UnrecognizedTaxBenefitsDecreasesDuringPeriodAbstract_14A7C9E4C5C0F5A70857FB840C2792A3" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsDecreasesResultingFromPriorPeriodTaxPositions" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsDecreasesResultingFromPriorPeriodTaxPositions_6874DDF7635E5C12CFD6FB840C271025" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_UnrecognizedTaxBenefitsDecreasesDuringPeriodAbstract_14A7C9E4C5C0F5A70857FB840C2792A3" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsDecreasesResultingFromPriorPeriodTaxPositions_6874DDF7635E5C12CFD6FB840C271025" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsDecreasesResultingFromSettlementsWithTaxingAuthorities" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsDecreasesResultingFromSettlementsWithTaxingAuthorities_76AC4B97ADC27232243FFB840C28FBEE" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_UnrecognizedTaxBenefitsDecreasesDuringPeriodAbstract_14A7C9E4C5C0F5A70857FB840C2792A3" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsDecreasesResultingFromSettlementsWithTaxingAuthorities_76AC4B97ADC27232243FFB840C28FBEE" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsReductionsResultingFromLapseOfApplicableStatuteOfLimitations" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsReductionsResultingFromLapseOfApplicableStatuteOfLimitations_25F2295F8E9C2F42D363FB840C28EECD" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_UnrecognizedTaxBenefitsDecreasesDuringPeriodAbstract_14A7C9E4C5C0F5A70857FB840C2792A3" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsReductionsResultingFromLapseOfApplicableStatuteOfLimitations_25F2295F8E9C2F42D363FB840C28EECD" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_UnrecognizedTaxBenefitsReductionsResultingFromOther" xlink:label="loc_iart_UnrecognizedTaxBenefitsReductionsResultingFromOther_0A391B6C9D2613E07F4FFB9322301E43" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_568FB4FD7324FC809F12FB840C278CB2" xlink:to="loc_iart_UnrecognizedTaxBenefitsReductionsResultingFromOther_0A391B6C9D2613E07F4FFB9322301E43" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_UnrecognizedTaxBenefits" xlink:label="loc_us-gaap_UnrecognizedTaxBenefits_A93448194E87CAC15152FB840C2D5362" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_568FB4FD7324FC809F12FB840C278CB2" xlink:to="loc_us-gaap_UnrecognizedTaxBenefits_A93448194E87CAC15152FB840C2D5362" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/IncomeTaxesTables" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_6B2FF0E2CA77F54D633A227F1A864D2E" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock_6A527109BF1A03A3719B227F1A8614F2" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_6B2FF0E2CA77F54D633A227F1A864D2E" xlink:to="loc_us-gaap_ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock_6A527109BF1A03A3719B227F1A8614F2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock_DA042BBAE64EA06B9FA0227F1A865A6F" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_6B2FF0E2CA77F54D633A227F1A864D2E" xlink:to="loc_us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock_DA042BBAE64EA06B9FA0227F1A865A6F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfComponentsOfIncomeTaxExpenseBenefitTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfComponentsOfIncomeTaxExpenseBenefitTableTextBlock_3E8364F0A29993FAD6A8227F1A876965" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_6B2FF0E2CA77F54D633A227F1A864D2E" xlink:to="loc_us-gaap_ScheduleOfComponentsOfIncomeTaxExpenseBenefitTableTextBlock_3E8364F0A29993FAD6A8227F1A876965" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock_AD9F904229D60F042E07227F1A875482" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_6B2FF0E2CA77F54D633A227F1A864D2E" xlink:to="loc_us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock_AD9F904229D60F042E07227F1A875482" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfUnrecognizedTaxBenefitsRollForwardTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfUnrecognizedTaxBenefitsRollForwardTableTextBlock_52A86A7B1774C218D370227F1A87BFF1" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_6B2FF0E2CA77F54D633A227F1A864D2E" xlink:to="loc_us-gaap_ScheduleOfUnrecognizedTaxBenefitsRollForwardTableTextBlock_52A86A7B1774C218D370227F1A87BFF1" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/LeasesAndRelatedPartyLeases" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="loc_us-gaap_LeasesAbstract_0BAB464920379ADC146455ED5878ABA3" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OperatingLeasesOfLessorDisclosureTextBlock" xlink:label="loc_us-gaap_OperatingLeasesOfLessorDisclosureTextBlock_7D7B4C3F7E06A64D5B8855ED587851C1" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_0BAB464920379ADC146455ED5878ABA3" xlink:to="loc_us-gaap_OperatingLeasesOfLessorDisclosureTextBlock_7D7B4C3F7E06A64D5B8855ED587851C1" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/LeasesAndRelatedPartyLeasesNarrativeDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="loc_us-gaap_LeasesAbstract_6C7129C7999955FA0B5455285A2437A4" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfOperatingLeasedAssetsTable" xlink:label="loc_us-gaap_ScheduleOfOperatingLeasedAssetsTable_873ABB6B109A961BA58555285A24564C" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_6C7129C7999955FA0B5455285A2437A4" xlink:to="loc_us-gaap_ScheduleOfOperatingLeasedAssetsTable_873ABB6B109A961BA58555285A24564C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PropertySubjectToOrAvailableForOperatingLeaseAxis" xlink:label="loc_us-gaap_PropertySubjectToOrAvailableForOperatingLeaseAxis_EA1D5A61E1B0B585A16355285A243916" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfOperatingLeasedAssetsTable_873ABB6B109A961BA58555285A24564C" xlink:to="loc_us-gaap_PropertySubjectToOrAvailableForOperatingLeaseAxis_EA1D5A61E1B0B585A16355285A243916" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PropertySubjectToOrAvailableForOperatingLeaseDomain" xlink:label="loc_us-gaap_PropertySubjectToOrAvailableForOperatingLeaseDomain_853F362AEF6D3C1D2DC955285A24736C" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertySubjectToOrAvailableForOperatingLeaseAxis_EA1D5A61E1B0B585A16355285A243916" xlink:to="loc_us-gaap_PropertySubjectToOrAvailableForOperatingLeaseDomain_853F362AEF6D3C1D2DC955285A24736C" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_FiveYearOptionLeaseFromNovember12032ThroughOctober312037Member" xlink:label="loc_iart_FiveYearOptionLeaseFromNovember12032ThroughOctober312037Member_9B4D992B79D9CFA2B73155285A24A359" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertySubjectToOrAvailableForOperatingLeaseDomain_853F362AEF6D3C1D2DC955285A24736C" xlink:to="loc_iart_FiveYearOptionLeaseFromNovember12032ThroughOctober312037Member_9B4D992B79D9CFA2B73155285A24A359" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_FiveYearOptionLeaseFromNovember12037ThroughOctober312042Member" xlink:label="loc_iart_FiveYearOptionLeaseFromNovember12037ThroughOctober312042Member_63B61E1242254571F86555285A2409D4" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertySubjectToOrAvailableForOperatingLeaseDomain_853F362AEF6D3C1D2DC955285A24736C" xlink:to="loc_iart_FiveYearOptionLeaseFromNovember12037ThroughOctober312042Member_63B61E1242254571F86555285A2409D4" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis" xlink:label="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_E1A94EF397BDA13F5B8355285A248FB0" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfOperatingLeasedAssetsTable_873ABB6B109A961BA58555285A24564C" xlink:to="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_E1A94EF397BDA13F5B8355285A248FB0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RelatedPartyDomain" xlink:label="loc_us-gaap_RelatedPartyDomain_3AD5F763C1734640E51755285A240295" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_E1A94EF397BDA13F5B8355285A248FB0" xlink:to="loc_us-gaap_RelatedPartyDomain_3AD5F763C1734640E51755285A240295" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_RelatedPartyMember" xlink:label="loc_iart_RelatedPartyMember_3048DF1D2D07410CA67255285A242D25" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyDomain_3AD5F763C1734640E51755285A240295" xlink:to="loc_iart_RelatedPartyMember_3048DF1D2D07410CA67255285A242D25" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OperatingLeasedAssetsLineItems" xlink:label="loc_us-gaap_OperatingLeasedAssetsLineItems_9F05740E02C62DDAD3EC55285A247EEF" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfOperatingLeasedAssetsTable_873ABB6B109A961BA58555285A24564C" xlink:to="loc_us-gaap_OperatingLeasedAssetsLineItems_9F05740E02C62DDAD3EC55285A247EEF" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OperatingLeasesRentExpenseNet" xlink:label="loc_us-gaap_OperatingLeasesRentExpenseNet_EE6E2B8BD67B757FAAC555285A24A1BB" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_9F05740E02C62DDAD3EC55285A247EEF" xlink:to="loc_us-gaap_OperatingLeasesRentExpenseNet_EE6E2B8BD67B757FAAC555285A24A1BB" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TermOfLease" xlink:label="loc_iart_TermOfLease_3C96E432F9B126A75E0455285A244A21" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_9F05740E02C62DDAD3EC55285A247EEF" xlink:to="loc_iart_TermOfLease_3C96E432F9B126A75E0455285A244A21" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_OptionToRenewLease" xlink:label="loc_iart_OptionToRenewLease_1D9FB1A2D17FB1A983DE55285A2459C2" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_9F05740E02C62DDAD3EC55285A247EEF" xlink:to="loc_iart_OptionToRenewLease_1D9FB1A2D17FB1A983DE55285A2459C2" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_PaymentPerYearToRelatedPartyLessor" xlink:label="loc_iart_PaymentPerYearToRelatedPartyLessor_6CA0400FD916EA11B1BF55285A24E6E2" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_9F05740E02C62DDAD3EC55285A247EEF" xlink:to="loc_iart_PaymentPerYearToRelatedPartyLessor_6CA0400FD916EA11B1BF55285A24E6E2" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_PercentOfManufacturingFacilityOwnedByCorporationWhoseShareholdersAreTrustsWhoseBeneficiariesIncludeFamilyMembersOfCompanysFormerChairman" xlink:label="loc_iart_PercentOfManufacturingFacilityOwnedByCorporationWhoseShareholdersAreTrustsWhoseBeneficiariesIncludeFamilyMembersOfCompanysFormerChairman_C75B8DF8F26C97CE6B6955285A2415A3" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_9F05740E02C62DDAD3EC55285A247EEF" xlink:to="loc_iart_PercentOfManufacturingFacilityOwnedByCorporationWhoseShareholdersAreTrustsWhoseBeneficiariesIncludeFamilyMembersOfCompanysFormerChairman_C75B8DF8F26C97CE6B6955285A2415A3" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_AnnualRateOfLeaseAgreement" xlink:label="loc_iart_AnnualRateOfLeaseAgreement_7C24C08C4A616B40803455285A25D33C" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_9F05740E02C62DDAD3EC55285A247EEF" xlink:to="loc_iart_AnnualRateOfLeaseAgreement_7C24C08C4A616B40803455285A25D33C" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_OptionToExtendLeaseYears" xlink:label="loc_iart_OptionToExtendLeaseYears_EDA6B2DFCD002EF86D0455285A2571E8" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_9F05740E02C62DDAD3EC55285A247EEF" xlink:to="loc_iart_OptionToExtendLeaseYears_EDA6B2DFCD002EF86D0455285A2571E8" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_PeriodForExtendedLease" xlink:label="loc_iart_PeriodForExtendedLease_4C68E9BF5BBDD89BFC2A55285A251601" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_9F05740E02C62DDAD3EC55285A247EEF" xlink:to="loc_iart_PeriodForExtendedLease_4C68E9BF5BBDD89BFC2A55285A251601" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/LeasesAndRelatedPartyLeasesScheduleOfFutureMinimumLeasePaymentsForCapitalLeasesDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="loc_us-gaap_LeasesAbstract_8B6C4A953F8175E7DD5446F7B869040F" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CapitalLeasesFutureMinimumPaymentsDueCurrent" xlink:label="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsDueCurrent_66A0A7D5C58F37B0E90546F7B86AAF04" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_8B6C4A953F8175E7DD5446F7B869040F" xlink:to="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsDueCurrent_66A0A7D5C58F37B0E90546F7B86AAF04" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CapitalLeasesFutureMinimumPaymentsDue" xlink:label="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsDue_5264749DD65ABC4F2DDF46F7B86A3A81" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_8B6C4A953F8175E7DD5446F7B869040F" xlink:to="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsDue_5264749DD65ABC4F2DDF46F7B86A3A81" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CapitalLeasesFutureMinimumPaymentsInterestIncludedInPayments" xlink:label="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsInterestIncludedInPayments_B12817C7CD76F9B0377446F7B86AB225" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_8B6C4A953F8175E7DD5446F7B869040F" xlink:to="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsInterestIncludedInPayments_B12817C7CD76F9B0377446F7B86AB225" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CapitalLeasesFutureMinimumPaymentsPresentValueOfNetMinimumPayments" xlink:label="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsPresentValueOfNetMinimumPayments_CBD5CF5A697D99895DB946F7B86ACC02" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_8B6C4A953F8175E7DD5446F7B869040F" xlink:to="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsPresentValueOfNetMinimumPayments_CBD5CF5A697D99895DB946F7B86ACC02" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/LeasesAndRelatedPartyLeasesScheduleOfMinimumLeasePaymentsDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="loc_us-gaap_LeasesAbstract_2DA0005B72A5032444C046F7B870516E" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfOperatingLeasedAssetsTable" xlink:label="loc_us-gaap_ScheduleOfOperatingLeasedAssetsTable_ADC3CC794D2888BFCDDD46F7B872601E" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_2DA0005B72A5032444C046F7B870516E" xlink:to="loc_us-gaap_ScheduleOfOperatingLeasedAssetsTable_ADC3CC794D2888BFCDDD46F7B872601E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PropertySubjectToOrAvailableForOperatingLeaseAxis" xlink:label="loc_us-gaap_PropertySubjectToOrAvailableForOperatingLeaseAxis_8A4F87278C3CDC3FB50746F7B8723614" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfOperatingLeasedAssetsTable_ADC3CC794D2888BFCDDD46F7B872601E" xlink:to="loc_us-gaap_PropertySubjectToOrAvailableForOperatingLeaseAxis_8A4F87278C3CDC3FB50746F7B8723614" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PropertySubjectToOrAvailableForOperatingLeaseDomain" xlink:label="loc_us-gaap_PropertySubjectToOrAvailableForOperatingLeaseDomain_0D033EC34A9CBECABC3D46F7B872C5C5" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertySubjectToOrAvailableForOperatingLeaseAxis_8A4F87278C3CDC3FB50746F7B8723614" xlink:to="loc_us-gaap_PropertySubjectToOrAvailableForOperatingLeaseDomain_0D033EC34A9CBECABC3D46F7B872C5C5" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_RelatedPartiesMember" xlink:label="loc_iart_RelatedPartiesMember_DE3AC512CBF4B99F745546F7B8737BD3" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertySubjectToOrAvailableForOperatingLeaseDomain_0D033EC34A9CBECABC3D46F7B872C5C5" xlink:to="loc_iart_RelatedPartiesMember_DE3AC512CBF4B99F745546F7B8737BD3" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_ThirdPartiesMember" xlink:label="loc_iart_ThirdPartiesMember_00A97A94B0B2EF0E9EA746F7B8735C93" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertySubjectToOrAvailableForOperatingLeaseDomain_0D033EC34A9CBECABC3D46F7B872C5C5" xlink:to="loc_iart_ThirdPartiesMember_00A97A94B0B2EF0E9EA746F7B8735C93" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OperatingLeasedAssetsLineItems" xlink:label="loc_us-gaap_OperatingLeasedAssetsLineItems_C01974CE57EE7527C13C46F7B874B20B" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfOperatingLeasedAssetsTable_ADC3CC794D2888BFCDDD46F7B872601E" xlink:to="loc_us-gaap_OperatingLeasedAssetsLineItems_C01974CE57EE7527C13C46F7B874B20B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueCurrent" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueCurrent_EF48F9660303FCAAF4C846F7B874C8F1" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_C01974CE57EE7527C13C46F7B874B20B" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueCurrent_EF48F9660303FCAAF4C846F7B874C8F1" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueInTwoYears" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInTwoYears_241E8E5F0C681757027F46F7B87415D0" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_C01974CE57EE7527C13C46F7B874B20B" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInTwoYears_241E8E5F0C681757027F46F7B87415D0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueInThreeYears" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInThreeYears_2B79ED3B64FA3F26543646F7B8747D2E" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_C01974CE57EE7527C13C46F7B874B20B" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInThreeYears_2B79ED3B64FA3F26543646F7B8747D2E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFourYears" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFourYears_D8AF20FE07EF3B1C707D46F7B8749278" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_C01974CE57EE7527C13C46F7B874B20B" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFourYears_D8AF20FE07EF3B1C707D46F7B8749278" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFiveYears" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFiveYears_1B7B7FC38CC9D9056D6546F7B87410F0" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_C01974CE57EE7527C13C46F7B874B20B" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFiveYears_1B7B7FC38CC9D9056D6546F7B87410F0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueThereafter" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueThereafter_1C58D50FF447D475508346F7B8745968" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_C01974CE57EE7527C13C46F7B874B20B" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueThereafter_1C58D50FF447D475508346F7B8745968" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDue" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDue_5F5A85DE53D8EE1AE22046F7B87468D0" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_C01974CE57EE7527C13C46F7B874B20B" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDue_5F5A85DE53D8EE1AE22046F7B87468D0" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/LeasesAndRelatedPartyLeasesTables" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="loc_us-gaap_LeasesAbstract_C01BE5D1776C6AF73318227F1757EEFC" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OperatingLeasesOfLesseeDisclosureTextBlock" xlink:label="loc_us-gaap_OperatingLeasesOfLesseeDisclosureTextBlock_4731D4E2BDF6BDE0CD02227F17574A4F" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_C01BE5D1776C6AF73318227F1757EEFC" xlink:to="loc_us-gaap_OperatingLeasesOfLesseeDisclosureTextBlock_4731D4E2BDF6BDE0CD02227F17574A4F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfFutureMinimumLeasePaymentsForCapitalLeasesTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfFutureMinimumLeasePaymentsForCapitalLeasesTableTextBlock_D238B8697D68EA97062D227F17575427" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_C01BE5D1776C6AF73318227F1757EEFC" xlink:to="loc_us-gaap_ScheduleOfFutureMinimumLeasePaymentsForCapitalLeasesTableTextBlock_D238B8697D68EA97062D227F17575427" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/NetLossIncomePerShare" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_us-gaap_EarningsPerShareAbstract_9E37163CACFD05DBD39EF0D3749FD891" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EarningsPerShareTextBlock" xlink:label="loc_us-gaap_EarningsPerShareTextBlock_5C0965054B432EA0488BF0D3749FAB37" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_9E37163CACFD05DBD39EF0D3749FD891" xlink:to="loc_us-gaap_EarningsPerShareTextBlock_5C0965054B432EA0488BF0D3749FAB37" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/NetLossIncomePerShareBasicAndDilutedNetIncomePerShareDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_us-gaap_EarningsPerShareAbstract_CD57AFDCEA11EECD27A815B8C4643C0E" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EarningsPerShareBasicAbstract" xlink:label="loc_us-gaap_EarningsPerShareBasicAbstract_A285BB4D7F25288B2C7515B8C464804F" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_CD57AFDCEA11EECD27A815B8C4643C0E" xlink:to="loc_us-gaap_EarningsPerShareBasicAbstract_A285BB4D7F25288B2C7515B8C464804F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromContinuingOperations" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperations_097CDFA2E1A21E52172515B8C464A5B8" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_A285BB4D7F25288B2C7515B8C464804F" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperations_097CDFA2E1A21E52172515B8C464A5B8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_A24F1EF822341FCE211A15B8C46450F0" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_A285BB4D7F25288B2C7515B8C464804F" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_A24F1EF822341FCE211A15B8C46450F0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_7B8D9481CE534FBC0DDA15B8C46405AD" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_A285BB4D7F25288B2C7515B8C464804F" xlink:to="loc_us-gaap_NetIncomeLoss_7B8D9481CE534FBC0DDA15B8C46405AD" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_3668B224A7026F68A15B15B8C464626F" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_A285BB4D7F25288B2C7515B8C464804F" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_3668B224A7026F68A15B15B8C464626F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsPerBasicShare" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsPerBasicShare_B19DF9CE90629C5CCD0A15B8C464E748" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_A285BB4D7F25288B2C7515B8C464804F" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsPerBasicShare_B19DF9CE90629C5CCD0A15B8C464E748" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerBasicShare" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerBasicShare_4BE56A8C8515A53EE97015B8C4642976" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_A285BB4D7F25288B2C7515B8C464804F" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerBasicShare_4BE56A8C8515A53EE97015B8C4642976" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EarningsPerShareBasic" xlink:label="loc_us-gaap_EarningsPerShareBasic_53969CB5D3E991EF3A2015B8C4653297" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_A285BB4D7F25288B2C7515B8C464804F" xlink:to="loc_us-gaap_EarningsPerShareBasic_53969CB5D3E991EF3A2015B8C4653297" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EarningsPerShareDilutedAbstract" xlink:label="loc_us-gaap_EarningsPerShareDilutedAbstract_AC958B28B897ABA55BF315B8C465AB68" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_A285BB4D7F25288B2C7515B8C464804F" xlink:to="loc_us-gaap_EarningsPerShareDilutedAbstract_AC958B28B897ABA55BF315B8C465AB68" xlink:type="arc" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_AC958B28B897ABA55BF315B8C465AB68" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperations_097CDFA2E1A21E52172515B8C464A5B8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_34F318B7E4166A897B6C15B8C4654386" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_AC958B28B897ABA55BF315B8C465AB68" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_34F318B7E4166A897B6C15B8C4654386" xlink:type="arc" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_AC958B28B897ABA55BF315B8C465AB68" xlink:to="loc_us-gaap_NetIncomeLoss_7B8D9481CE534FBC0DDA15B8C46405AD" xlink:type="arc" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_AC958B28B897ABA55BF315B8C465AB68" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_3668B224A7026F68A15B15B8C464626F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DilutiveSecuritiesAbstract" xlink:label="loc_us-gaap_DilutiveSecuritiesAbstract_59E0CAF6E92F4A0A8CE715B8C4652BA1" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_A285BB4D7F25288B2C7515B8C464804F" xlink:to="loc_us-gaap_DilutiveSecuritiesAbstract_59E0CAF6E92F4A0A8CE715B8C4652BA1" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities_94DC4307FB6F80EE9FCF15B8C4655CD2" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DilutiveSecuritiesAbstract_59E0CAF6E92F4A0A8CE715B8C4652BA1" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities_94DC4307FB6F80EE9FCF15B8C4655CD2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_9E159E54173D485A040E15B8C46596D4" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DilutiveSecuritiesAbstract_59E0CAF6E92F4A0A8CE715B8C4652BA1" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_9E159E54173D485A040E15B8C46596D4" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_D69B1498B88F3533E0E015B8C4651126" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DilutiveSecuritiesAbstract_59E0CAF6E92F4A0A8CE715B8C4652BA1" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_D69B1498B88F3533E0E015B8C4651126" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare_B501A402A49F335C355215B8C4652DE2" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DilutiveSecuritiesAbstract_59E0CAF6E92F4A0A8CE715B8C4652BA1" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare_B501A402A49F335C355215B8C4652DE2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerDilutedShare" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerDilutedShare_4D22002282F74DF87C5B15B8C465454C" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DilutiveSecuritiesAbstract_59E0CAF6E92F4A0A8CE715B8C4652BA1" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxPerDilutedShare_4D22002282F74DF87C5B15B8C465454C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EarningsPerShareDiluted" xlink:label="loc_us-gaap_EarningsPerShareDiluted_D24C8C75F1BF991BFA6A15B8C465C524" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DilutiveSecuritiesAbstract_59E0CAF6E92F4A0A8CE715B8C4652BA1" xlink:to="loc_us-gaap_EarningsPerShareDiluted_D24C8C75F1BF991BFA6A15B8C465C524" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/NetLossIncomePerShareNarrativeDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_us-gaap_EarningsPerShareAbstract_1C8C949E392CD58A9CD2F0D3749AE695" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_BB059BBACBD34938C2ADF0D3749AFAD0" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_1C8C949E392CD58A9CD2F0D3749AE695" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_BB059BBACBD34938C2ADF0D3749AFAD0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="loc_us-gaap_DisposalGroupClassificationAxis_1C70B3C6FB723DD26690F0D3749A7826" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_BB059BBACBD34938C2ADF0D3749AFAD0" xlink:to="loc_us-gaap_DisposalGroupClassificationAxis_1C70B3C6FB723DD26690F0D3749A7826" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="loc_us-gaap_DisposalGroupClassificationDomain_16FD0BAA4E4DDEB747F7F0D3749AA155" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationAxis_1C70B3C6FB723DD26690F0D3749A7826" xlink:to="loc_us-gaap_DisposalGroupClassificationDomain_16FD0BAA4E4DDEB747F7F0D3749AA155" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember" xlink:label="loc_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_0BC3572063C1FF36E0A2F0D3749A133B" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationDomain_16FD0BAA4E4DDEB747F7F0D3749AA155" xlink:to="loc_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_0BC3572063C1FF36E0A2F0D3749A133B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_DEC3A5D163704E6BB48BF0D3749AAE78" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_BB059BBACBD34938C2ADF0D3749AFAD0" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_DEC3A5D163704E6BB48BF0D3749AAE78" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_97B73C0B03D199E02C73F0D3749AED50" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_DEC3A5D163704E6BB48BF0D3749AAE78" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_97B73C0B03D199E02C73F0D3749AED50" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SeaSpineInc.Member" xlink:label="loc_iart_SeaSpineInc.Member_E0164E47BB249E9DE9D8F0D3749ACEEF" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_97B73C0B03D199E02C73F0D3749AED50" xlink:to="loc_iart_SeaSpineInc.Member_E0164E47BB249E9DE9D8F0D3749ACEEF" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_C3F18AD9981AE3A333E1F0D3749AC1DF" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_BB059BBACBD34938C2ADF0D3749AFAD0" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_C3F18AD9981AE3A333E1F0D3749AC1DF" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPlanModificationIncrementalCompensationCost" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPlanModificationIncrementalCompensationCost_E01C30B26940B676D243F0D3749AE0F1" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_C3F18AD9981AE3A333E1F0D3749AC1DF" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPlanModificationIncrementalCompensationCost_E01C30B26940B676D243F0D3749AE0F1" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AllocatedShareBasedCompensationExpense" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_CDFEFF2A1D040C100C2AF0D3749A2CF9" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_C3F18AD9981AE3A333E1F0D3749AC1DF" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_CDFEFF2A1D040C100C2AF0D3749A2CF9" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized_89EA24BB2581F4B5593FF0D3749A79C4" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_C3F18AD9981AE3A333E1F0D3749AC1DF" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized_89EA24BB2581F4B5593FF0D3749A79C4" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_B5C1D2491FAA2E828731F0D3749B603A" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_C3F18AD9981AE3A333E1F0D3749AC1DF" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_B5C1D2491FAA2E828731F0D3749B603A" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_AdditionalEPSShares" xlink:label="loc_iart_AdditionalEPSShares_37CC6A9AD22FA241A5B6F0D3749B9577" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_C3F18AD9981AE3A333E1F0D3749AC1DF" xlink:to="loc_iart_AdditionalEPSShares_37CC6A9AD22FA241A5B6F0D3749B9577" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/NetLossIncomePerShareTables" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_us-gaap_EarningsPerShareAbstract_B55F48D46B0571140B82F0D3749D48A0" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_681632102B398CEC63BAF0D3749DFEBA" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_B55F48D46B0571140B82F0D3749D48A0" xlink:to="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_681632102B398CEC63BAF0D3749DFEBA" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/RetirementBenefitPlans" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CompensationAndRetirementDisclosureAbstract" xlink:label="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_A7320902156A9AB93DFC55ED5899963B" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PensionAndOtherPostretirementBenefitsDisclosureTextBlock" xlink:label="loc_us-gaap_PensionAndOtherPostretirementBenefitsDisclosureTextBlock_7B9574150E250F2F58C655ED58993F5F" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_A7320902156A9AB93DFC55ED5899963B" xlink:to="loc_us-gaap_PensionAndOtherPostretirementBenefitsDisclosureTextBlock_7B9574150E250F2F58C655ED58993F5F" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/RetirementBenefitPlansChangesInProjectedBenefitObligationAndFairValueOfPlanAssetsDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CompensationAndRetirementDisclosureAbstract" xlink:label="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_047952943D1D8F923F92050A046A8DDA" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward" xlink:label="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_4FF2F51114AC3EFD29B0050A046B5F6B" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_047952943D1D8F923F92050A046A8DDA" xlink:to="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_4FF2F51114AC3EFD29B0050A046B5F6B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DefinedBenefitPlanContributionsByEmployer" xlink:label="loc_us-gaap_DefinedBenefitPlanContributionsByEmployer_9DE024B1C93382D21C60050A046BC979" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DefinedBenefitPlanChangeInFairValueOfPlanAssetsRollForward_4FF2F51114AC3EFD29B0050A046B5F6B" xlink:to="loc_us-gaap_DefinedBenefitPlanContributionsByEmployer_9DE024B1C93382D21C60050A046BC979" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/RetirementBenefitPlansNarrativeDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CompensationAndRetirementDisclosureAbstract" xlink:label="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_8F89D7D0030916F08F5A050A0461848E" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DefinedBenefitPlanContributionsByEmployer" xlink:label="loc_us-gaap_DefinedBenefitPlanContributionsByEmployer_2E05FF9BCEFAC842F5A7050A04623B10" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_8F89D7D0030916F08F5A050A0461848E" xlink:to="loc_us-gaap_DefinedBenefitPlanContributionsByEmployer_2E05FF9BCEFAC842F5A7050A04623B10" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DefinedBenefitPlanRecognizedNetGainLossDueToSettlementsAndCurtailments1" xlink:label="loc_us-gaap_DefinedBenefitPlanRecognizedNetGainLossDueToSettlementsAndCurtailments1_495C0F08DC935535965E050A0462D66D" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_8F89D7D0030916F08F5A050A0461848E" xlink:to="loc_us-gaap_DefinedBenefitPlanRecognizedNetGainLossDueToSettlementsAndCurtailments1_495C0F08DC935535965E050A0462D66D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DefinedContributionPlanCostRecognized" xlink:label="loc_us-gaap_DefinedContributionPlanCostRecognized_F54832A6C9D432E25B49050A046253DD" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_8F89D7D0030916F08F5A050A0461848E" xlink:to="loc_us-gaap_DefinedContributionPlanCostRecognized_F54832A6C9D432E25B49050A046253DD" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/ScheduleIiValuationAndQualifyingAccounts" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ValuationAndQualifyingAccountsAbstract" xlink:label="loc_us-gaap_ValuationAndQualifyingAccountsAbstract_DCA9DF2401DC08DDCC8C55ED58196ACB" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfValuationAndQualifyingAccountsDisclosureTextBlock" xlink:label="loc_us-gaap_ScheduleOfValuationAndQualifyingAccountsDisclosureTextBlock_76146E12061299CF283C55ED581945C4" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ValuationAndQualifyingAccountsAbstract_DCA9DF2401DC08DDCC8C55ED58196ACB" xlink:to="loc_us-gaap_ScheduleOfValuationAndQualifyingAccountsDisclosureTextBlock_76146E12061299CF283C55ED581945C4" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/ScheduleIiValuationAndQualifyingAccountsDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ValuationAndQualifyingAccountsAbstract" xlink:label="loc_us-gaap_ValuationAndQualifyingAccountsAbstract_6EC434960AA0DF0B7DCD9EBABA271867" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ValuationAndQualifyingAccountsDisclosureTable" xlink:label="loc_us-gaap_ValuationAndQualifyingAccountsDisclosureTable_0E1DC4E2599820A346AD9EBABA282E8C" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ValuationAndQualifyingAccountsAbstract_6EC434960AA0DF0B7DCD9EBABA271867" xlink:to="loc_us-gaap_ValuationAndQualifyingAccountsDisclosureTable_0E1DC4E2599820A346AD9EBABA282E8C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ValuationAllowancesAndReservesTypeAxis" xlink:label="loc_us-gaap_ValuationAllowancesAndReservesTypeAxis_FBE32BD7732651128A6F9EBABA28172F" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ValuationAndQualifyingAccountsDisclosureTable_0E1DC4E2599820A346AD9EBABA282E8C" xlink:to="loc_us-gaap_ValuationAllowancesAndReservesTypeAxis_FBE32BD7732651128A6F9EBABA28172F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ValuationAllowancesAndReservesDomain" xlink:label="loc_us-gaap_ValuationAllowancesAndReservesDomain_D1106608FDF2D6A146419EBABA28F019" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ValuationAllowancesAndReservesTypeAxis_FBE32BD7732651128A6F9EBABA28172F" xlink:to="loc_us-gaap_ValuationAllowancesAndReservesDomain_D1106608FDF2D6A146419EBABA28F019" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AllowanceForDoubtfulAccountsMember" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsMember_338A8257C45C961A78A59EBABA28D33B" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ValuationAllowancesAndReservesDomain_D1106608FDF2D6A146419EBABA28F019" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsMember_338A8257C45C961A78A59EBABA28D33B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ValuationAllowanceOfDeferredTaxAssetsMember" xlink:label="loc_us-gaap_ValuationAllowanceOfDeferredTaxAssetsMember_BA9C1FD80D49A61507CB9EBABA293C6C" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ValuationAllowancesAndReservesDomain_D1106608FDF2D6A146419EBABA28F019" xlink:to="loc_us-gaap_ValuationAllowanceOfDeferredTaxAssetsMember_BA9C1FD80D49A61507CB9EBABA293C6C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ValuationAndQualifyingAccountsDisclosureLineItems" xlink:label="loc_us-gaap_ValuationAndQualifyingAccountsDisclosureLineItems_BA0B00F526C136738DD19EBABA297F07" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ValuationAndQualifyingAccountsDisclosureTable_0E1DC4E2599820A346AD9EBABA282E8C" xlink:to="loc_us-gaap_ValuationAndQualifyingAccountsDisclosureLineItems_BA0B00F526C136738DD19EBABA297F07" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_MovementInValuationAllowancesAndReservesRollForward" xlink:label="loc_us-gaap_MovementInValuationAllowancesAndReservesRollForward_46120389E0D1E3C1881E9EBABA29096A" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ValuationAndQualifyingAccountsDisclosureLineItems_BA0B00F526C136738DD19EBABA297F07" xlink:to="loc_us-gaap_MovementInValuationAllowancesAndReservesRollForward_46120389E0D1E3C1881E9EBABA29096A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ValuationAllowancesAndReservesBalance" xlink:label="loc_us-gaap_ValuationAllowancesAndReservesBalance_0EF49818524CA3C088779EBABA294D8A" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MovementInValuationAllowancesAndReservesRollForward_46120389E0D1E3C1881E9EBABA29096A" xlink:to="loc_us-gaap_ValuationAllowancesAndReservesBalance_0EF49818524CA3C088779EBABA294D8A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ValuationAllowancesAndReservesChargedToCostAndExpense" xlink:label="loc_us-gaap_ValuationAllowancesAndReservesChargedToCostAndExpense_AB18FDBBFA6514719E129EBABA2975F7" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MovementInValuationAllowancesAndReservesRollForward_46120389E0D1E3C1881E9EBABA29096A" xlink:to="loc_us-gaap_ValuationAllowancesAndReservesChargedToCostAndExpense_AB18FDBBFA6514719E129EBABA2975F7" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ValuationAllowancesAndReservesChargedToOtherAccounts" xlink:label="loc_us-gaap_ValuationAllowancesAndReservesChargedToOtherAccounts_49628C70713D6DDB852C9EBABA29157C" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MovementInValuationAllowancesAndReservesRollForward_46120389E0D1E3C1881E9EBABA29096A" xlink:to="loc_us-gaap_ValuationAllowancesAndReservesChargedToOtherAccounts_49628C70713D6DDB852C9EBABA29157C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ValuationAllowancesAndReservesDeductions" xlink:label="loc_us-gaap_ValuationAllowancesAndReservesDeductions_480DC0EA481CCE0029719EBABA2954EF" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MovementInValuationAllowancesAndReservesRollForward_46120389E0D1E3C1881E9EBABA29096A" xlink:to="loc_us-gaap_ValuationAllowancesAndReservesDeductions_480DC0EA481CCE0029719EBABA2954EF" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ValuationAllowancesAndReservesBalance" xlink:label="loc_us-gaap_ValuationAllowancesAndReservesBalance_8D25B136D7170CB1DFA59EBABA2A5503" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MovementInValuationAllowancesAndReservesRollForward_46120389E0D1E3C1881E9EBABA29096A" xlink:to="loc_us-gaap_ValuationAllowancesAndReservesBalance_8D25B136D7170CB1DFA59EBABA2A5503" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/SegmentAndGeographicInformation" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="loc_us-gaap_SegmentReportingAbstract_B29F07D29E16B474F47555ED582D3EA0" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SegmentReportingDisclosureTextBlock" xlink:label="loc_us-gaap_SegmentReportingDisclosureTextBlock_77EAFBC03BEEB59CAC5255ED582DF055" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_B29F07D29E16B474F47555ED582D3EA0" xlink:to="loc_us-gaap_SegmentReportingDisclosureTextBlock_77EAFBC03BEEB59CAC5255ED582DF055" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/SegmentAndGeographicInformationNarrativeDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="loc_us-gaap_SegmentReportingAbstract_CACD84850C8E1BAB698F50EAE6C31DD1" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NumberOfReportableSegments" xlink:label="loc_us-gaap_NumberOfReportableSegments_8B87AB8C5DAF72E174F750EAE6C45B4C" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_CACD84850C8E1BAB698F50EAE6C31DD1" xlink:to="loc_us-gaap_NumberOfReportableSegments_8B87AB8C5DAF72E174F750EAE6C45B4C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_2BD553E3A4223E434BFF50EAE6C3E91D" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_CACD84850C8E1BAB698F50EAE6C31DD1" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_2BD553E3A4223E434BFF50EAE6C3E91D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_4905CFA5B456718CEFF650EAE6C3139C" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_2BD553E3A4223E434BFF50EAE6C3E91D" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_4905CFA5B456718CEFF650EAE6C3139C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_8EDE00C4B7E9561B8C8C50EAE6C3EC02" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_4905CFA5B456718CEFF650EAE6C3139C" xlink:to="loc_us-gaap_SegmentDomain_8EDE00C4B7E9561B8C8C50EAE6C3EC02" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SpecialtySurgicalSolutionsMember" xlink:label="loc_iart_SpecialtySurgicalSolutionsMember_313EB600387E345B181A50EAE6C3C5D6" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_8EDE00C4B7E9561B8C8C50EAE6C3EC02" xlink:to="loc_iart_SpecialtySurgicalSolutionsMember_313EB600387E345B181A50EAE6C3C5D6" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_69E59BB4BB9E868CAF5750EAE6C4CBB1" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_2BD553E3A4223E434BFF50EAE6C3E91D" xlink:to="loc_us-gaap_SegmentReportingInformationLineItems_69E59BB4BB9E868CAF5750EAE6C4CBB1" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SegmentReportingInformationNumberofProductsOffered" xlink:label="loc_iart_SegmentReportingInformationNumberofProductsOffered_8105B412FB25516E9B7A50EAE6C4A394" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_69E59BB4BB9E868CAF5750EAE6C4CBB1" xlink:to="loc_iart_SegmentReportingInformationNumberofProductsOffered_8105B412FB25516E9B7A50EAE6C4A394" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/SegmentAndGeographicInformationNetSalesAndProfitByReportableSegmentDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="loc_us-gaap_SegmentReportingAbstract_2E23FD4509D0AA5E5884EB95E81F6896" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable" xlink:label="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable_F19F9E0C04852D9A6424EB95E820F3CD" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_2E23FD4509D0AA5E5884EB95E81F6896" xlink:to="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable_F19F9E0C04852D9A6424EB95E820F3CD" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ProductOrServiceAxis" xlink:label="loc_us-gaap_ProductOrServiceAxis_C1841DEAEB49179FB8E4EB95E82027E4" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable_F19F9E0C04852D9A6424EB95E820F3CD" xlink:to="loc_us-gaap_ProductOrServiceAxis_C1841DEAEB49179FB8E4EB95E82027E4" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ProductsAndServicesDomain" xlink:label="loc_us-gaap_ProductsAndServicesDomain_E5A296FB088D8698B70EEB95E8205095" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductOrServiceAxis_C1841DEAEB49179FB8E4EB95E82027E4" xlink:to="loc_us-gaap_ProductsAndServicesDomain_E5A296FB088D8698B70EEB95E8205095" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_USNeurosurgeryMember" xlink:label="loc_iart_USNeurosurgeryMember_FA0863A65AAB7BD275DEEB95E820B8BE" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductsAndServicesDomain_E5A296FB088D8698B70EEB95E8205095" xlink:to="loc_iart_USNeurosurgeryMember_FA0863A65AAB7BD275DEEB95E820B8BE" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_USInstrumentsMember" xlink:label="loc_iart_USInstrumentsMember_75599FD7DFDBBC9367F3EB95E8202D41" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductsAndServicesDomain_E5A296FB088D8698B70EEB95E8205095" xlink:to="loc_iart_USInstrumentsMember_75599FD7DFDBBC9367F3EB95E8202D41" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems" xlink:label="loc_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems_B830D5B3FC3DD8C8A8FDEB95E820BF9E" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable_F19F9E0C04852D9A6424EB95E820F3CD" xlink:to="loc_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems_B830D5B3FC3DD8C8A8FDEB95E820BF9E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SalesRevenueGoodsNet" xlink:label="loc_us-gaap_SalesRevenueGoodsNet_E7CBA9263A7CF9B1B34DEB95E820F764" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems_B830D5B3FC3DD8C8A8FDEB95E820BF9E" xlink:to="loc_us-gaap_SalesRevenueGoodsNet_E7CBA9263A7CF9B1B34DEB95E820F764" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SegmentProfitLoss" xlink:label="loc_iart_SegmentProfitLoss_18D2D7B9E72D0A22A323EB95E8209F2F" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems_B830D5B3FC3DD8C8A8FDEB95E820BF9E" xlink:to="loc_iart_SegmentProfitLoss_18D2D7B9E72D0A22A323EB95E8209F2F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AmortizationOfIntangibleAssets" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_0EE78EDD28E0E66BC044EB95E820A4CC" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems_B830D5B3FC3DD8C8A8FDEB95E820BF9E" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_0EE78EDD28E0E66BC044EB95E820A4CC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherGeneralExpense" xlink:label="loc_us-gaap_OtherGeneralExpense_5EA663B95C8ADA18FC86EB95E820F2A8" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems_B830D5B3FC3DD8C8A8FDEB95E820BF9E" xlink:to="loc_us-gaap_OtherGeneralExpense_5EA663B95C8ADA18FC86EB95E820F2A8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaap_OperatingIncomeLoss_043F5428A0F51387FD62EB95E82190B6" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems_B830D5B3FC3DD8C8A8FDEB95E820BF9E" xlink:to="loc_us-gaap_OperatingIncomeLoss_043F5428A0F51387FD62EB95E82190B6" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/SegmentAndGeographicInformationTables" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="loc_us-gaap_SegmentReportingAbstract_60C7BCB60DDB76FBB805610CB906E397" xlink:type="locator" />
    <loc xlink:href="iart-20151231.xsd#iart_ScheduleOfNetSalesAndOperatingIncomeByReportableSegmentTableTableTextBlock" xlink:label="loc_iart_ScheduleOfNetSalesAndOperatingIncomeByReportableSegmentTableTableTextBlock_0BE4BE8B14F7893CB951610CB9067490" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_60C7BCB60DDB76FBB805610CB906E397" xlink:to="loc_iart_ScheduleOfNetSalesAndOperatingIncomeByReportableSegmentTableTableTextBlock_0BE4BE8B14F7893CB951610CB9067490" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock_C3D2E0F73A5D33EBCA28610D7655D381" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_60C7BCB60DDB76FBB805610CB906E397" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock_C3D2E0F73A5D33EBCA28610D7655D381" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/SegmentAndGeographicInformationTotalRevenueByMajorGeographicAreaDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="loc_us-gaap_SegmentReportingAbstract_29E7C26D2684657A5DA650EAE6B94010" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_78D86A6507F47C9DC70750EAE6B9689B" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_29E7C26D2684657A5DA650EAE6B94010" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_78D86A6507F47C9DC70750EAE6B9689B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StatementGeographicalAxis" xlink:label="loc_us-gaap_StatementGeographicalAxis_2BBD24354F8900AF787050EAE6B93A38" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_78D86A6507F47C9DC70750EAE6B9689B" xlink:to="loc_us-gaap_StatementGeographicalAxis_2BBD24354F8900AF787050EAE6B93A38" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SegmentGeographicalDomain" xlink:label="loc_us-gaap_SegmentGeographicalDomain_D8F9F216E0F40B6C8D3E50EAE6B947B9" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementGeographicalAxis_2BBD24354F8900AF787050EAE6B93A38" xlink:to="loc_us-gaap_SegmentGeographicalDomain_D8F9F216E0F40B6C8D3E50EAE6B947B9" xlink:type="arc" />
    <loc xlink:href="http://xbrl.sec.gov/country/2013/country-2013-01-31.xsd#country_US" xlink:label="loc_country_US_69CBDEB6878E65151E8950EAE6B9DB0C" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentGeographicalDomain_D8F9F216E0F40B6C8D3E50EAE6B947B9" xlink:to="loc_country_US_69CBDEB6878E65151E8950EAE6B9DB0C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EuropeMember" xlink:label="loc_us-gaap_EuropeMember_C776AD264330966F512F50EAE6B941F9" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentGeographicalDomain_D8F9F216E0F40B6C8D3E50EAE6B947B9" xlink:to="loc_us-gaap_EuropeMember_C776AD264330966F512F50EAE6B941F9" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_RestOfWorldMember" xlink:label="loc_iart_RestOfWorldMember_024555CB169013844A9050EAE6B9345E" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentGeographicalDomain_D8F9F216E0F40B6C8D3E50EAE6B947B9" xlink:to="loc_iart_RestOfWorldMember_024555CB169013844A9050EAE6B9345E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_223CC642A4F175B628A550EAE6B9DECE" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_78D86A6507F47C9DC70750EAE6B9689B" xlink:to="loc_us-gaap_SegmentReportingInformationLineItems_223CC642A4F175B628A550EAE6B9DECE" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SalesRevenueGoodsNet" xlink:label="loc_us-gaap_SalesRevenueGoodsNet_509EDCC3CB169628A868511CB9C27805" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_223CC642A4F175B628A550EAE6B9DECE" xlink:to="loc_us-gaap_SalesRevenueGoodsNet_509EDCC3CB169628A868511CB9C27805" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NoncurrentAssets" xlink:label="loc_us-gaap_NoncurrentAssets_4BDBBE051FB565FF526550EAE6B9905D" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_223CC642A4F175B628A550EAE6B9DECE" xlink:to="loc_us-gaap_NoncurrentAssets_4BDBBE051FB565FF526550EAE6B9905D" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/SelectedQuarterlyInformationUnaudited" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SelectedQuarterlyFinancialInformationAbstract" xlink:label="loc_us-gaap_SelectedQuarterlyFinancialInformationAbstract_94B348977DD7D2DC992555ED5820C300" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_QuarterlyFinancialInformationTextBlock" xlink:label="loc_us-gaap_QuarterlyFinancialInformationTextBlock_AD3174533D9BA2C8118455ED5820C5FB" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SelectedQuarterlyFinancialInformationAbstract_94B348977DD7D2DC992555ED5820C300" xlink:to="loc_us-gaap_QuarterlyFinancialInformationTextBlock_AD3174533D9BA2C8118455ED5820C5FB" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/SelectedQuarterlyInformationUnauditedSelectedQuarterlyInformationDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SelectedQuarterlyFinancialInformationAbstract" xlink:label="loc_us-gaap_SelectedQuarterlyFinancialInformationAbstract_B298FFF384B3BE8BDB16FB840B1192BE" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SalesRevenueGoodsNet" xlink:label="loc_us-gaap_SalesRevenueGoodsNet_77CD9424E78B2A58FE82FB840B1150B1" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SelectedQuarterlyFinancialInformationAbstract_B298FFF384B3BE8BDB16FB840B1192BE" xlink:to="loc_us-gaap_SalesRevenueGoodsNet_77CD9424E78B2A58FE82FB840B1150B1" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_GrossProfit" xlink:label="loc_us-gaap_GrossProfit_2301EA2143F427BA5B14FB840B117CA9" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SelectedQuarterlyFinancialInformationAbstract_B298FFF384B3BE8BDB16FB840B1192BE" xlink:to="loc_us-gaap_GrossProfit_2301EA2143F427BA5B14FB840B117CA9" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromContinuingOperations" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperations_9F0491E2519E21A71F4CFB840B1118CD" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SelectedQuarterlyFinancialInformationAbstract_B298FFF384B3BE8BDB16FB840B1192BE" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperations_9F0491E2519E21A71F4CFB840B1118CD" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsPerBasicShare" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsPerBasicShare_37C74EAFA59D830251DBFB840B115D34" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SelectedQuarterlyFinancialInformationAbstract_B298FFF384B3BE8BDB16FB840B1192BE" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsPerBasicShare_37C74EAFA59D830251DBFB840B115D34" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare_B82015FD7B4E4066BD2DFB840B11F33B" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SelectedQuarterlyFinancialInformationAbstract_B298FFF384B3BE8BDB16FB840B1192BE" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare_B82015FD7B4E4066BD2DFB840B11F33B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_8FC667A8D17EA84BDEE2FB840B11EF88" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SelectedQuarterlyFinancialInformationAbstract_B298FFF384B3BE8BDB16FB840B1192BE" xlink:to="loc_us-gaap_NetIncomeLoss_8FC667A8D17EA84BDEE2FB840B11EF88" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EarningsPerShareBasic" xlink:label="loc_us-gaap_EarningsPerShareBasic_740A3F147D40FFD1EACEFB840B11EF82" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SelectedQuarterlyFinancialInformationAbstract_B298FFF384B3BE8BDB16FB840B1192BE" xlink:to="loc_us-gaap_EarningsPerShareBasic_740A3F147D40FFD1EACEFB840B11EF82" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EarningsPerShareDiluted" xlink:label="loc_us-gaap_EarningsPerShareDiluted_8A4E09AE394542D83C15FB840B11988F" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SelectedQuarterlyFinancialInformationAbstract_B298FFF384B3BE8BDB16FB840B1192BE" xlink:to="loc_us-gaap_EarningsPerShareDiluted_8A4E09AE394542D83C15FB840B11988F" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/SelectedQuarterlyInformationUnauditedTables" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SelectedQuarterlyFinancialInformationAbstract" xlink:label="loc_us-gaap_SelectedQuarterlyFinancialInformationAbstract_DEEA3A41AC7F89A110E0227F183BCAF2" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfQuarterlyFinancialInformationTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfQuarterlyFinancialInformationTableTextBlock_AD2FAA69E4941A8AB3D7227F183BDA9F" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SelectedQuarterlyFinancialInformationAbstract_DEEA3A41AC7F89A110E0227F183BCAF2" xlink:to="loc_us-gaap_ScheduleOfQuarterlyFinancialInformationTableTextBlock_AD2FAA69E4941A8AB3D7227F183BDA9F" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/StockBasedCompensation" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_BFE3829D20CD0936A28755ED5917CD3A" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_02B67E19B379FF3CFD8655ED5917AD48" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_BFE3829D20CD0936A28755ED5917CD3A" xlink:to="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_02B67E19B379FF3CFD8655ED5917AD48" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/StockBasedCompensationNarrativeDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_EE375BA3AB909536DBDB138261D4CA3D" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2CA9D2DD80F9B234F18E138261D44569" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_EE375BA3AB909536DBDB138261D4CA3D" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2CA9D2DD80F9B234F18E138261D44569" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="loc_us-gaap_DisposalGroupClassificationAxis_C5A1B7C9706FB4947252138261D43BA5" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2CA9D2DD80F9B234F18E138261D44569" xlink:to="loc_us-gaap_DisposalGroupClassificationAxis_C5A1B7C9706FB4947252138261D43BA5" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="loc_us-gaap_DisposalGroupClassificationDomain_52AFBD140658B00C8377138261D4238A" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationAxis_C5A1B7C9706FB4947252138261D43BA5" xlink:to="loc_us-gaap_DisposalGroupClassificationDomain_52AFBD140658B00C8377138261D4238A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember" xlink:label="loc_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_F43A4C90119D4CFA3E26138261D41F7D" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationDomain_52AFBD140658B00C8377138261D4238A" xlink:to="loc_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_F43A4C90119D4CFA3E26138261D41F7D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_38BEC6747F90AFFCC6B9138261D50AAB" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2CA9D2DD80F9B234F18E138261D44569" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_38BEC6747F90AFFCC6B9138261D50AAB" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_B8C92532BD3721BDE814138261D5198B" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_38BEC6747F90AFFCC6B9138261D50AAB" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_B8C92532BD3721BDE814138261D5198B" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SeaSpineInc.Member" xlink:label="loc_iart_SeaSpineInc.Member_90FC78070B0D47875F8A138261D59276" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_B8C92532BD3721BDE814138261D5198B" xlink:to="loc_iart_SeaSpineInc.Member_90FC78070B0D47875F8A138261D59276" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SubsidiarySaleOfStockAxis" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_E71EC053D0A7C7892E4D138261D5B93F" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2CA9D2DD80F9B234F18E138261D44569" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_E71EC053D0A7C7892E4D138261D5B93F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SaleOfStockNameOfTransactionDomain" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_6F099719BBB3941A9FC7138261D5C053" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_E71EC053D0A7C7892E4D138261D5B93F" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_6F099719BBB3941A9FC7138261D5C053" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EmployeeStockMember" xlink:label="loc_us-gaap_EmployeeStockMember_73200AE68143ED3EEEA1138261D504F4" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_6F099719BBB3941A9FC7138261D5C053" xlink:to="loc_us-gaap_EmployeeStockMember_73200AE68143ED3EEEA1138261D504F4" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PlanNameAxis" xlink:label="loc_us-gaap_PlanNameAxis_94EBA88610682A919FE8138261D530F0" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2CA9D2DD80F9B234F18E138261D44569" xlink:to="loc_us-gaap_PlanNameAxis_94EBA88610682A919FE8138261D530F0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PlanNameDomain" xlink:label="loc_us-gaap_PlanNameDomain_C5040FD00D18BA0458AA138261D5AC10" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_94EBA88610682A919FE8138261D530F0" xlink:to="loc_us-gaap_PlanNameDomain_C5040FD00D18BA0458AA138261D5AC10" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TwoThousandAndTwoThousandOnePlanMember" xlink:label="loc_iart_TwoThousandAndTwoThousandOnePlanMember_8D048672D96769644CBF138261D59D8F" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_C5040FD00D18BA0458AA138261D5AC10" xlink:to="loc_iart_TwoThousandAndTwoThousandOnePlanMember_8D048672D96769644CBF138261D59D8F" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TwoThousandThreePlanMember" xlink:label="loc_iart_TwoThousandThreePlanMember_B28943EA1EDD81876BE5138261D547A6" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_C5040FD00D18BA0458AA138261D5AC10" xlink:to="loc_iart_TwoThousandThreePlanMember_B28943EA1EDD81876BE5138261D547A6" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_4C2F152DEE341D4F2189138261D5CFB6" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2CA9D2DD80F9B234F18E138261D44569" xlink:to="loc_us-gaap_AwardTypeAxis_4C2F152DEE341D4F2189138261D5CFB6" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_BC2B6FE736ADEF6DFDD7138261D5400F" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_4C2F152DEE341D4F2189138261D5CFB6" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_BC2B6FE736ADEF6DFDD7138261D5400F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EmployeeStockOptionMember" xlink:label="loc_us-gaap_EmployeeStockOptionMember_06A0E31F841CD86E5BC0138261D54D26" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_BC2B6FE736ADEF6DFDD7138261D5400F" xlink:to="loc_us-gaap_EmployeeStockOptionMember_06A0E31F841CD86E5BC0138261D54D26" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_RestrictedStockPerformanceStockAndContractStockMember" xlink:label="loc_iart_RestrictedStockPerformanceStockAndContractStockMember_3200EDBAB30B706F2B94138261D5D31B" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_BC2B6FE736ADEF6DFDD7138261D5400F" xlink:to="loc_iart_RestrictedStockPerformanceStockAndContractStockMember_3200EDBAB30B706F2B94138261D5D31B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RestrictedStockUnitsRSUMember" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_69030CD1520C4B0F9AF3138261D5108E" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_BC2B6FE736ADEF6DFDD7138261D5400F" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_69030CD1520C4B0F9AF3138261D5108E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_TitleOfIndividualAxis" xlink:label="loc_us-gaap_TitleOfIndividualAxis_AE1E278EC5F7AE103489138261D5E5C9" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2CA9D2DD80F9B234F18E138261D44569" xlink:to="loc_us-gaap_TitleOfIndividualAxis_AE1E278EC5F7AE103489138261D5E5C9" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_TitleOfIndividualWithRelationshipToEntityDomain" xlink:label="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_33491D3BED766CC23DCC138261D525EC" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TitleOfIndividualAxis_AE1E278EC5F7AE103489138261D5E5C9" xlink:to="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_33491D3BED766CC23DCC138261D525EC" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_NonFormerChiefExecutiveOfficerMember" xlink:label="loc_iart_NonFormerChiefExecutiveOfficerMember_B8A097893AB22028991F138261D5B880" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_33491D3BED766CC23DCC138261D525EC" xlink:to="loc_iart_NonFormerChiefExecutiveOfficerMember_B8A097893AB22028991F138261D5B880" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RangeAxis" xlink:label="loc_us-gaap_RangeAxis_C28CDB83AC0C72001547138261D5F2B2" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2CA9D2DD80F9B234F18E138261D44569" xlink:to="loc_us-gaap_RangeAxis_C28CDB83AC0C72001547138261D5F2B2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_77F755004D97B35DC932138261D6957F" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeAxis_C28CDB83AC0C72001547138261D5F2B2" xlink:to="loc_us-gaap_RangeMember_77F755004D97B35DC932138261D6957F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_MinimumMember" xlink:label="loc_us-gaap_MinimumMember_FFD9279BD7934B07D662138261D672FB" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeMember_77F755004D97B35DC932138261D6957F" xlink:to="loc_us-gaap_MinimumMember_FFD9279BD7934B07D662138261D672FB" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_MaximumMember" xlink:label="loc_us-gaap_MaximumMember_E0C768371B1FCA7199A3138261D632D2" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeMember_77F755004D97B35DC932138261D6957F" xlink:to="loc_us-gaap_MaximumMember_E0C768371B1FCA7199A3138261D632D2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_2CA9D2DD80F9B234F18E138261D44569" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized_4AE42415400818DB500C138261D67BDC" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized_4AE42415400818DB500C138261D67BDC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_2C5C8B86EF1EE680B083138261D69C0D" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_2C5C8B86EF1EE680B083138261D69C0D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardSharesIssuedInPeriod" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardSharesIssuedInPeriod_6954ABA1E1B2E1666F3C138261D6FA7F" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardSharesIssuedInPeriod_6954ABA1E1B2E1666F3C138261D6FA7F" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_EmployeeStockPurchasePlanProceeds" xlink:label="loc_iart_EmployeeStockPurchasePlanProceeds_CC72EEDE4522C12F738D138261D62DC7" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_iart_EmployeeStockPurchasePlanProceeds_CC72EEDE4522C12F738D138261D62DC7" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfPlans" xlink:label="loc_iart_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfPlans_ABFE8A3E48D3C26F96EB138261D69ED7" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_iart_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfPlans_ABFE8A3E48D3C26F96EB138261D69ED7" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_IncreaseInAuthorizedShares" xlink:label="loc_iart_IncreaseInAuthorizedShares_EF0D8307AF20ACB22AAA138261D6CA4B" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_iart_IncreaseInAuthorizedShares_EF0D8307AF20ACB22AAA138261D6CA4B" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_ShareBasedCompensationArrangementByShareBasedPaymentAwardVestingPeriodEmployees" xlink:label="loc_iart_ShareBasedCompensationArrangementByShareBasedPaymentAwardVestingPeriodEmployees_0C65D895D3D0CE776B5A138261D641BF" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_iart_ShareBasedCompensationArrangementByShareBasedPaymentAwardVestingPeriodEmployees_0C65D895D3D0CE776B5A138261D641BF" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_ShareBasedCompensationArrangementByShareBasedPaymentAwardExpirationPeriodEmployees" xlink:label="loc_iart_ShareBasedCompensationArrangementByShareBasedPaymentAwardExpirationPeriodEmployees_D77EA9B518C104E2DA8E138261D651E9" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_iart_ShareBasedCompensationArrangementByShareBasedPaymentAwardExpirationPeriodEmployees_D77EA9B518C104E2DA8E138261D651E9" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_ShareBasedCompensationArrangementByShareBasedPaymentAwardExpirationPeriodDirectors" xlink:label="loc_iart_ShareBasedCompensationArrangementByShareBasedPaymentAwardExpirationPeriodDirectors_0F23ED993517A4531C08138261D63FDC" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_iart_ShareBasedCompensationArrangementByShareBasedPaymentAwardExpirationPeriodDirectors_0F23ED993517A4531C08138261D63FDC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_9732A5ABAAADD8ABAB5A138261D62A07" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_9732A5ABAAADD8ABAB5A138261D62A07" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPlanModificationIncrementalCompensationCost" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPlanModificationIncrementalCompensationCost_9C2E938D2670C07CB593138261DCC241" xlink:type="locator" />
    <presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPlanModificationIncrementalCompensationCost_9C2E938D2670C07CB593138261DCC241" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_278BC6A9C63DAC7B2A4A138261DCC120" xlink:type="locator" />
    <presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_278BC6A9C63DAC7B2A4A138261DCC120" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized_38510A20AE70FAA57E28138261DC7519" xlink:type="locator" />
    <presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized_38510A20AE70FAA57E28138261DC7519" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_7323B1206889D20D7B5B138261DC0431" xlink:type="locator" />
    <presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_7323B1206889D20D7B5B138261DC0431" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_ECBD764FD8D35029F668138261DC2F38" xlink:type="locator" />
    <presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_ECBD764FD8D35029F668138261DC2F38" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationCashReceivedFromExerciseOfStockOptions" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationCashReceivedFromExerciseOfStockOptions_AE428EDA85B6B5336D82138261DC38D8" xlink:type="locator" />
    <presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationCashReceivedFromExerciseOfStockOptions_AE428EDA85B6B5336D82138261DC38D8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AllocatedShareBasedCompensationExpense" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_D07862134DBE96C5F6AE138261DC0DF3" xlink:type="locator" />
    <presentationArc order="17" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_D07862134DBE96C5F6AE138261DC0DF3" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodTotalFairValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodTotalFairValue_BDCDC88E56DC1527D960138261DCB7DB" xlink:type="locator" />
    <presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodTotalFairValue_BDCDC88E56DC1527D960138261DCB7DB" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardRequisiteServicePeriod1" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardRequisiteServicePeriod1_5BBBCCD6C0C0B800D5A7138261DC3465" xlink:type="locator" />
    <presentationArc order="19" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardRequisiteServicePeriod1_5BBBCCD6C0C0B800D5A7138261DC3465" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_NonIssuedVestedRestrictedStockUnits" xlink:label="loc_iart_NonIssuedVestedRestrictedStockUnits_955B559D8B9388CBCCBB138261DCD7E9" xlink:type="locator" />
    <presentationArc order="20" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B567D538E52DC80B68A6138261D63990" xlink:to="loc_iart_NonIssuedVestedRestrictedStockUnits_955B559D8B9388CBCCBB138261DCD7E9" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/StockBasedCompensationSummaryOfEmployeeStockBasedCompensationExpenseDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_2230126D2534E75C42FB227F1827C819" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable" xlink:label="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_3C97FF0D78980D2B9AA5227F18274FDD" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_2230126D2534E75C42FB227F1827C819" xlink:to="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_3C97FF0D78980D2B9AA5227F18274FDD" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_940CA2E341C5DDF341F7227F1827B84B" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_3C97FF0D78980D2B9AA5227F18274FDD" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_940CA2E341C5DDF341F7227F1827B84B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_42EC550D096C95AB178E227F18276B78" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_940CA2E341C5DDF341F7227F1827B84B" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_42EC550D096C95AB178E227F18276B78" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SellingGeneralAndAdministrativeMember" xlink:label="loc_iart_SellingGeneralAndAdministrativeMember_067C4B8B36E5EC67152A227F18272DA0" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_42EC550D096C95AB178E227F18276B78" xlink:to="loc_iart_SellingGeneralAndAdministrativeMember_067C4B8B36E5EC67152A227F18272DA0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseMember" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseMember_8246C61658EB1864463C227F18283F14" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_42EC550D096C95AB178E227F18276B78" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseMember_8246C61658EB1864463C227F18283F14" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CostOfSalesMember" xlink:label="loc_us-gaap_CostOfSalesMember_F5E6F1F2FE77A0F95FCC227F18289414" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_42EC550D096C95AB178E227F18276B78" xlink:to="loc_us-gaap_CostOfSalesMember_F5E6F1F2FE77A0F95FCC227F18289414" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_4C16F272B95CF26C2455227F1828475F" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_3C97FF0D78980D2B9AA5227F18274FDD" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_4C16F272B95CF26C2455227F1828475F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AllocatedShareBasedCompensationExpense" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_4B2D3AF6EE3F93CC933D227F18281710" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_4C16F272B95CF26C2455227F1828475F" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_4B2D3AF6EE3F93CC933D227F18281710" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationTaxBenefitFromCompensationExpense" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationTaxBenefitFromCompensationExpense_447419EBD885FF254C92227F1828D3B0" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_4C16F272B95CF26C2455227F1828475F" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationTaxBenefitFromCompensationExpense_447419EBD885FF254C92227F1828D3B0" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AllocatedShareBasedCompensationExpenseNetOfTax" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpenseNetOfTax_464088C4D89D14356A68227F182878B7" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_4C16F272B95CF26C2455227F1828475F" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpenseNetOfTax_464088C4D89D14356A68227F182878B7" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/StockBasedCompensationSummaryOfStockOptionActivityDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_F2049E44EA54B5F27A7613D63D469CD7" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_0F10A932BC58E0666B6513D63D47C985" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_F2049E44EA54B5F27A7613D63D469CD7" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_0F10A932BC58E0666B6513D63D47C985" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_299712AF49014904BE7A13D63D472C2B" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_0F10A932BC58E0666B6513D63D47C985" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_299712AF49014904BE7A13D63D472C2B" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsModificationUponSpinOff" xlink:label="loc_iart_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsModificationUponSpinOff_A0EE3D10904DC90776AF13D63D47D4F9" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_0F10A932BC58E0666B6513D63D47C985" xlink:to="loc_iart_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsModificationUponSpinOff_A0EE3D10904DC90776AF13D63D47D4F9" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod_0C57EC311288CFB6E1FE13D63D478388" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_0F10A932BC58E0666B6513D63D47C985" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod_0C57EC311288CFB6E1FE13D63D478388" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_CAD4857432C39ACA28EB13D63D4701D6" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_0F10A932BC58E0666B6513D63D47C985" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_CAD4857432C39ACA28EB13D63D4701D6" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_81B908BD1F372374BB6713D63D474AB8" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_0F10A932BC58E0666B6513D63D47C985" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_81B908BD1F372374BB6713D63D474AB8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_C22684199164C5A5584313D63D47CA2F" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_0F10A932BC58E0666B6513D63D47C985" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_C22684199164C5A5584313D63D47CA2F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_BB9CD2432965DB27D75013D63D48B233" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_F2049E44EA54B5F27A7613D63D469CD7" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_BB9CD2432965DB27D75013D63D48B233" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_4BB49FA592EAA90ADFA413D63D486201" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_F2049E44EA54B5F27A7613D63D469CD7" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_4BB49FA592EAA90ADFA413D63D486201" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_ED60D369720DCDA90B5213D63D480256" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_F2049E44EA54B5F27A7613D63D469CD7" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_ED60D369720DCDA90B5213D63D480256" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_3641C2F042E70E68182413D63D483D3F" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_ED60D369720DCDA90B5213D63D480256" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_3641C2F042E70E68182413D63D483D3F" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SharebasedCompensationArrangementsbySharebasedPaymentAwardOptionsModificationUponSpinOffWeightedAverageExercisePrice" xlink:label="loc_iart_SharebasedCompensationArrangementsbySharebasedPaymentAwardOptionsModificationUponSpinOffWeightedAverageExercisePrice_B593F0817FD7A639DFFF13D63D4898E5" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_ED60D369720DCDA90B5213D63D480256" xlink:to="loc_iart_SharebasedCompensationArrangementsbySharebasedPaymentAwardOptionsModificationUponSpinOffWeightedAverageExercisePrice_B593F0817FD7A639DFFF13D63D4898E5" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_26346446323A32081A3813D63D486AD8" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_ED60D369720DCDA90B5213D63D480256" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_26346446323A32081A3813D63D486AD8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_88C7D2A74D42B524D77813D63D486ACC" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_ED60D369720DCDA90B5213D63D480256" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_88C7D2A74D42B524D77813D63D486ACC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_12D9C1AC55E47B66A2A913D63D483874" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_ED60D369720DCDA90B5213D63D480256" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_12D9C1AC55E47B66A2A913D63D483874" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_E5754D7730CB47A592A413D63D482442" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_ED60D369720DCDA90B5213D63D480256" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_E5754D7730CB47A592A413D63D482442" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_F5B19F459BABD5ED0E0313D63D48BF43" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_F2049E44EA54B5F27A7613D63D469CD7" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_F5B19F459BABD5ED0E0313D63D48BF43" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_89412A46BB49B3C8272313D63D488810" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_F2049E44EA54B5F27A7613D63D469CD7" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_89412A46BB49B3C8272313D63D488810" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageRemainingContractualTerm1" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageRemainingContractualTerm1_C5CFFC95D1E26407F30E13D63D482454" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_F2049E44EA54B5F27A7613D63D469CD7" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageRemainingContractualTerm1_C5CFFC95D1E26407F30E13D63D482454" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1_9D9D209BBDF8F5A477D913D63D488F4A" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_F2049E44EA54B5F27A7613D63D469CD7" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1_9D9D209BBDF8F5A477D913D63D488F4A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_A87F4069101BCCFF937113D63D48F904" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_F2049E44EA54B5F27A7613D63D469CD7" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_A87F4069101BCCFF937113D63D48F904" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_E53B8A1653BA6EFE3CD213D63D482546" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_F2049E44EA54B5F27A7613D63D469CD7" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_E53B8A1653BA6EFE3CD213D63D482546" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue_52FBB1FE2E080C9D9CA813D63D48ED2D" xlink:type="locator" />
    <presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_F2049E44EA54B5F27A7613D63D469CD7" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue_52FBB1FE2E080C9D9CA813D63D48ED2D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_39912F05D491B2BF456A13D63D4995B9" xlink:type="locator" />
    <presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_F2049E44EA54B5F27A7613D63D469CD7" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_39912F05D491B2BF456A13D63D4995B9" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/StockBasedCompensationSummaryOfVestedAndUnvestedRsuDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_8D3FD60C2ED1DABA068813D63D3B8552" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_C83086AD82236FBFC75713D63D3B02E8" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_8D3FD60C2ED1DABA068813D63D3B8552" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_C83086AD82236FBFC75713D63D3B02E8" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_ScheduleOfShareBasedCompensationArrangementByShareBasedPaymentAwardVestedAndNonVestedAxis" xlink:label="loc_iart_ScheduleOfShareBasedCompensationArrangementByShareBasedPaymentAwardVestedAndNonVestedAxis_3EDBF54273A93493150613D63D3B925A" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_C83086AD82236FBFC75713D63D3B02E8" xlink:to="loc_iart_ScheduleOfShareBasedCompensationArrangementByShareBasedPaymentAwardVestedAndNonVestedAxis_3EDBF54273A93493150613D63D3B925A" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_ScheduleOfShareBasedCompensationArrangementByShareBasedPaymentAwardVestedAndNonVestedDomain" xlink:label="loc_iart_ScheduleOfShareBasedCompensationArrangementByShareBasedPaymentAwardVestedAndNonVestedDomain_E42E483D27501F4E1CC013D63D3B4C4F" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_ScheduleOfShareBasedCompensationArrangementByShareBasedPaymentAwardVestedAndNonVestedAxis_3EDBF54273A93493150613D63D3B925A" xlink:to="loc_iart_ScheduleOfShareBasedCompensationArrangementByShareBasedPaymentAwardVestedAndNonVestedDomain_E42E483D27501F4E1CC013D63D3B4C4F" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_ReleasedMember" xlink:label="loc_iart_ReleasedMember_08B8F817613A10A17F9E13D63D3C41A4" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_ScheduleOfShareBasedCompensationArrangementByShareBasedPaymentAwardVestedAndNonVestedDomain_E42E483D27501F4E1CC013D63D3B4C4F" xlink:to="loc_iart_ReleasedMember_08B8F817613A10A17F9E13D63D3C41A4" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_049B8864E1467053627C13D63D3C69E5" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_C83086AD82236FBFC75713D63D3B02E8" xlink:to="loc_us-gaap_AwardTypeAxis_049B8864E1467053627C13D63D3C69E5" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_DC5F9FCE5A8134C6075613D63D3CD97C" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_049B8864E1467053627C13D63D3C69E5" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_DC5F9FCE5A8134C6075613D63D3CD97C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RestrictedStockMember" xlink:label="loc_us-gaap_RestrictedStockMember_D59D780708A027B72A8113D63D3C0275" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_DC5F9FCE5A8134C6075613D63D3CD97C" xlink:to="loc_us-gaap_RestrictedStockMember_D59D780708A027B72A8113D63D3C0275" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockAppreciationRightsSARSMember" xlink:label="loc_us-gaap_StockAppreciationRightsSARSMember_5BF944B294577840D00F13D63D3C50ED" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_DC5F9FCE5A8134C6075613D63D3CD97C" xlink:to="loc_us-gaap_StockAppreciationRightsSARSMember_5BF944B294577840D00F13D63D3C50ED" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_D4B9ABC38CBC4DA8620D13D63D3C3E29" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_C83086AD82236FBFC75713D63D3B02E8" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_D4B9ABC38CBC4DA8620D13D63D3C3E29" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_B0EF94D171C0A9EAA2DB13D63D3C5206" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_D4B9ABC38CBC4DA8620D13D63D3C3E29" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_B0EF94D171C0A9EAA2DB13D63D3C5206" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_BC3F54E120C91E9C238413D63D3C485E" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_B0EF94D171C0A9EAA2DB13D63D3C5206" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_BC3F54E120C91E9C238413D63D3C485E" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SharebasedCompensationArrangementsbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsModificationUponSpinoffWeightedAverageGrantDateFairValueExercisePrice" xlink:label="loc_iart_SharebasedCompensationArrangementsbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsModificationUponSpinoffWeightedAverageGrantDateFairValueExercisePrice_46234B403BC08E5FA9D913D63D3D50F9" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_B0EF94D171C0A9EAA2DB13D63D3C5206" xlink:to="loc_iart_SharebasedCompensationArrangementsbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsModificationUponSpinoffWeightedAverageGrantDateFairValueExercisePrice_46234B403BC08E5FA9D913D63D3D50F9" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SharebasedCompensationArrangementsbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsSurrenderedUponSpinoffWeightedAverageGrantDateFairValueExercisePrice" xlink:label="loc_iart_SharebasedCompensationArrangementsbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsSurrenderedUponSpinoffWeightedAverageGrantDateFairValueExercisePrice_23C126C7F53F1E67738213D63D3D341E" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_B0EF94D171C0A9EAA2DB13D63D3C5206" xlink:to="loc_iart_SharebasedCompensationArrangementsbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsSurrenderedUponSpinoffWeightedAverageGrantDateFairValueExercisePrice_23C126C7F53F1E67738213D63D3D341E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_5B1F4934CDE1DBBA60FE13D63D3D9D05" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_B0EF94D171C0A9EAA2DB13D63D3C5206" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_5B1F4934CDE1DBBA60FE13D63D3D9D05" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue_93169739E9FEE664751413D63D3DD171" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_B0EF94D171C0A9EAA2DB13D63D3C5206" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue_93169739E9FEE664751413D63D3DD171" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_CBB26BABBF0E2D647A4913D63D3DDB5C" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_B0EF94D171C0A9EAA2DB13D63D3C5206" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_CBB26BABBF0E2D647A4913D63D3DDB5C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_D897D26DE429779CF60813D63D3D761E" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_B0EF94D171C0A9EAA2DB13D63D3C5206" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_D897D26DE429779CF60813D63D3D761E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_D6EB5837D1FD4934A57313D63D3D3E40" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_D4B9ABC38CBC4DA8620D13D63D3C3E29" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_D6EB5837D1FD4934A57313D63D3D3E40" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_F7855A35B4037771A2A513D63D3D7BEA" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_D6EB5837D1FD4934A57313D63D3D3E40" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_F7855A35B4037771A2A513D63D3D7BEA" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SharebasedCompensationArrangementbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsModificationUponSpinoffDescription" xlink:label="loc_iart_SharebasedCompensationArrangementbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsModificationUponSpinoffDescription_29625A11BA3A827188B313D63D3EEB2E" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_D6EB5837D1FD4934A57313D63D3D3E40" xlink:to="loc_iart_SharebasedCompensationArrangementbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsModificationUponSpinoffDescription_29625A11BA3A827188B313D63D3EEB2E" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SharebasedCompensationArrangementbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsSurrenderedUponSpinoffDescription" xlink:label="loc_iart_SharebasedCompensationArrangementbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsSurrenderedUponSpinoffDescription_3FDEB1AFDE4C06D1A5B513D63D3E6A39" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_D6EB5837D1FD4934A57313D63D3D3E40" xlink:to="loc_iart_SharebasedCompensationArrangementbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsSurrenderedUponSpinoffDescription_3FDEB1AFDE4C06D1A5B513D63D3E6A39" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_8B7682A442D67078F66413D63D3E4D4E" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_D6EB5837D1FD4934A57313D63D3D3E40" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_8B7682A442D67078F66413D63D3E4D4E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod_94331E3456B807D11E9813D63D3ECF70" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_D6EB5837D1FD4934A57313D63D3D3E40" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod_94331E3456B807D11E9813D63D3ECF70" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod_5F6DBAB64DD297D23EAC13D63D3E8A7E" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_D6EB5837D1FD4934A57313D63D3D3E40" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod_5F6DBAB64DD297D23EAC13D63D3E8A7E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_7B0C7CF319810737DCFD13D63D3E76E0" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_D6EB5837D1FD4934A57313D63D3D3E40" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_7B0C7CF319810737DCFD13D63D3E76E0" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/StockBasedCompensationSummaryOfWeightedAverageAssumptionsDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_360F31255A302824CE8940B004D4680A" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_B9B33F172F5AA2F4756E40B004D478E1" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_360F31255A302824CE8940B004D4680A" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_B9B33F172F5AA2F4756E40B004D478E1" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsWeightedAverageVolatilityRate" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsWeightedAverageVolatilityRate_44DD8E1444140F9AD83440B004D45008" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_360F31255A302824CE8940B004D4680A" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsWeightedAverageVolatilityRate_44DD8E1444140F9AD83440B004D45008" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_C670BF481E826FF8DA4B40B004D4784C" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_360F31255A302824CE8940B004D4680A" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_C670BF481E826FF8DA4B40B004D4784C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_0F7458C45A50BCC7FE0C40B004D40694" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_360F31255A302824CE8940B004D4680A" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_0F7458C45A50BCC7FE0C40B004D40694" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/StockBasedCompensationTables" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_278A5F59C707164EEE8E227F1A933D68" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfCompensationCostForShareBasedPaymentArrangementsAllocationOfShareBasedCompensationCostsByPlanTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfCompensationCostForShareBasedPaymentArrangementsAllocationOfShareBasedCompensationCostsByPlanTableTextBlock_373E7531FCE3328F63DA227F1A936227" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_278A5F59C707164EEE8E227F1A933D68" xlink:to="loc_us-gaap_ScheduleOfCompensationCostForShareBasedPaymentArrangementsAllocationOfShareBasedCompensationCostsByPlanTableTextBlock_373E7531FCE3328F63DA227F1A936227" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_1887EE0508A4AAAD8679227F1A9382F1" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_278A5F59C707164EEE8E227F1A933D68" xlink:to="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_1887EE0508A4AAAD8679227F1A9382F1" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_3F5CE4CAE939533B0E57227F1A9315F7" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_278A5F59C707164EEE8E227F1A933D68" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_3F5CE4CAE939533B0E57227F1A9315F7" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationRestrictedStockUnitsAwardActivityTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationRestrictedStockUnitsAwardActivityTableTextBlock_7976AB6DD77A9BD81729227F1A931EEC" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_278A5F59C707164EEE8E227F1A933D68" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationRestrictedStockUnitsAwardActivityTableTextBlock_7976AB6DD77A9BD81729227F1A931EEC" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/SummaryOfSignificantAccountingPolicies" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_2DFBD137101E8222BD9F55ED5A5AD258" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SignificantAccountingPoliciesTextBlock" xlink:label="loc_us-gaap_SignificantAccountingPoliciesTextBlock_CDFF16E1849520527A1C55ED5A5A9A6A" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_2DFBD137101E8222BD9F55ED5A5AD258" xlink:to="loc_us-gaap_SignificantAccountingPoliciesTextBlock_CDFF16E1849520527A1C55ED5A5A9A6A" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/SummaryOfSignificantAccountingPoliciesComponentsOfCompanysIdentifiableIntangibleAssetsDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_C401B8BC2F6119BA3D7260D3F81EE7ED" xlink:type="locator" />
    <loc xlink:href="iart-20151231.xsd#iart_ScheduleOfCompanysIdentifiableIntangibleAssetsTable" xlink:label="loc_iart_ScheduleOfCompanysIdentifiableIntangibleAssetsTable_CF4036C1422F76037F8560D3F81F1CCA" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_C401B8BC2F6119BA3D7260D3F81EE7ED" xlink:to="loc_iart_ScheduleOfCompanysIdentifiableIntangibleAssetsTable_CF4036C1422F76037F8560D3F81F1CCA" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_1FF3ED8F8247CAABA12160D3F81F25F1" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_ScheduleOfCompanysIdentifiableIntangibleAssetsTable_CF4036C1422F76037F8560D3F81F1CCA" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_1FF3ED8F8247CAABA12160D3F81F25F1" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_DA6804B7F7712792C80D60D3F81F7C88" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_1FF3ED8F8247CAABA12160D3F81F25F1" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_DA6804B7F7712792C80D60D3F81F7C88" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TrademarksBrandNamesMiltexCUSALuxtecandOmniTractMember" xlink:label="loc_iart_TrademarksBrandNamesMiltexCUSALuxtecandOmniTractMember_B6D14AC9E00A0C6C917F60D3F8203D0D" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_DA6804B7F7712792C80D60D3F81F7C88" xlink:to="loc_iart_TrademarksBrandNamesMiltexCUSALuxtecandOmniTractMember_B6D14AC9E00A0C6C917F60D3F8203D0D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RangeAxis" xlink:label="loc_us-gaap_RangeAxis_0DD5DAD11B71D29B614060D3F8209DE8" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_ScheduleOfCompanysIdentifiableIntangibleAssetsTable_CF4036C1422F76037F8560D3F81F1CCA" xlink:to="loc_us-gaap_RangeAxis_0DD5DAD11B71D29B614060D3F8209DE8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_98DC604134BF70DE7BCA60D3F8207506" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeAxis_0DD5DAD11B71D29B614060D3F8209DE8" xlink:to="loc_us-gaap_RangeMember_98DC604134BF70DE7BCA60D3F8207506" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_MinimumMember" xlink:label="loc_us-gaap_MinimumMember_CC80F77463D7859F996060D3F8205875" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeMember_98DC604134BF70DE7BCA60D3F8207506" xlink:to="loc_us-gaap_MinimumMember_CC80F77463D7859F996060D3F8205875" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_MaximumMember" xlink:label="loc_us-gaap_MaximumMember_2447B9032552E323268760D3F8204F50" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeMember_98DC604134BF70DE7BCA60D3F8207506" xlink:to="loc_us-gaap_MaximumMember_2447B9032552E323268760D3F8204F50" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_C57D4837B073182BB38B60D3F82091D2" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_ScheduleOfCompanysIdentifiableIntangibleAssetsTable_CF4036C1422F76037F8560D3F81F1CCA" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_C57D4837B073182BB38B60D3F82091D2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_3D46ABAE1AA79ED1E14060D3F8205850" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_C57D4837B073182BB38B60D3F82091D2" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_3D46ABAE1AA79ED1E14060D3F8205850" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_CompletedTechnologyMember" xlink:label="loc_iart_CompletedTechnologyMember_8656F1E42A370712E99E60D3F820191F" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_3D46ABAE1AA79ED1E14060D3F8205850" xlink:to="loc_iart_CompletedTechnologyMember_8656F1E42A370712E99E60D3F820191F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CustomerListsMember" xlink:label="loc_us-gaap_CustomerListsMember_86ADF8FF087BB8CC487560D3F820928E" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_3D46ABAE1AA79ED1E14060D3F8205850" xlink:to="loc_us-gaap_CustomerListsMember_86ADF8FF087BB8CC487560D3F820928E" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TrademarksBrandNamesMember" xlink:label="loc_iart_TrademarksBrandNamesMember_57217F1D9738951F65D160D3F820E5AB" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_3D46ABAE1AA79ED1E14060D3F8205850" xlink:to="loc_iart_TrademarksBrandNamesMember_57217F1D9738951F65D160D3F820E5AB" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SupplierRelationshipsIdentifiableIntangibleAssetsMember" xlink:label="loc_iart_SupplierRelationshipsIdentifiableIntangibleAssetsMember_DAA18C4B5B3C5FFC077B60D3F8205FBC" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_3D46ABAE1AA79ED1E14060D3F8205850" xlink:to="loc_iart_SupplierRelationshipsIdentifiableIntangibleAssetsMember_DAA18C4B5B3C5FFC077B60D3F8205FBC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherIntangibleAssetsMember" xlink:label="loc_us-gaap_OtherIntangibleAssetsMember_DA68F75AFAA0C568622E60D3F8202FD4" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_3D46ABAE1AA79ED1E14060D3F8205850" xlink:to="loc_us-gaap_OtherIntangibleAssetsMember_DA68F75AFAA0C568622E60D3F8202FD4" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InProcessResearchAndDevelopmentMember" xlink:label="loc_us-gaap_InProcessResearchAndDevelopmentMember_3349C4545AD7C380602660D3F820023C" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIntangibleAssetsMember_DA68F75AFAA0C568622E60D3F8202FD4" xlink:to="loc_us-gaap_InProcessResearchAndDevelopmentMember_3349C4545AD7C380602660D3F820023C" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_GoodwillAndOtherIntangibleAssetsLineItems" xlink:label="loc_iart_GoodwillAndOtherIntangibleAssetsLineItems_44EE3303D00AEE3FDC9160D3F8210135" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_ScheduleOfCompanysIdentifiableIntangibleAssetsTable_CF4036C1422F76037F8560D3F81F1CCA" xlink:to="loc_iart_GoodwillAndOtherIntangibleAssetsLineItems_44EE3303D00AEE3FDC9160D3F8210135" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_792B8AAF4571D14B0BC460D3F821A330" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_GoodwillAndOtherIntangibleAssetsLineItems_44EE3303D00AEE3FDC9160D3F8210135" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_792B8AAF4571D14B0BC460D3F821A330" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsGross" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_CEBA86D08BDB1BD2F3E560D3F821C650" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_GoodwillAndOtherIntangibleAssetsLineItems_44EE3303D00AEE3FDC9160D3F8210135" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_CEBA86D08BDB1BD2F3E560D3F821C650" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_73AEEA837BF79105D48960D3F821A5F4" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_GoodwillAndOtherIntangibleAssetsLineItems_44EE3303D00AEE3FDC9160D3F8210135" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_73AEEA837BF79105D48960D3F821A5F4" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_4C559F5E2F8E4124B93F60D3F821B613" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_GoodwillAndOtherIntangibleAssetsLineItems_44EE3303D00AEE3FDC9160D3F8210135" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_4C559F5E2F8E4124B93F60D3F821B613" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_7A003927BE4813120DFB60D3F821E4CE" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_GoodwillAndOtherIntangibleAssetsLineItems_44EE3303D00AEE3FDC9160D3F8210135" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsNet_7A003927BE4813120DFB60D3F821E4CE" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IntangibleAssetsGrossExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_2F2EFE683FA6E9DD4BFD60D3F8217079" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_GoodwillAndOtherIntangibleAssetsLineItems_44EE3303D00AEE3FDC9160D3F8210135" xlink:to="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_2F2EFE683FA6E9DD4BFD60D3F8217079" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_18D637301E564FB99A6E60D3F821BADC" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_GoodwillAndOtherIntangibleAssetsLineItems_44EE3303D00AEE3FDC9160D3F8210135" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_18D637301E564FB99A6E60D3F821BADC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherIndefiniteLivedIntangibleAssets" xlink:label="loc_us-gaap_OtherIndefiniteLivedIntangibleAssets_C39141D059E22E7042E360D3F8210B96" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_GoodwillAndOtherIntangibleAssetsLineItems_44EE3303D00AEE3FDC9160D3F8210135" xlink:to="loc_us-gaap_OtherIndefiniteLivedIntangibleAssets_C39141D059E22E7042E360D3F8210B96" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/SummaryOfSignificantAccountingPoliciesNarrativeDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_3A6D9829D78B57CD09F51977068430F5" xlink:type="locator" />
    <loc xlink:href="iart-20151231.xsd#iart_SummaryOfSignificantAccountingPoliciesTable" xlink:label="loc_iart_SummaryOfSignificantAccountingPoliciesTable_37134486D2208A9545E8197706847901" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_3A6D9829D78B57CD09F51977068430F5" xlink:to="loc_iart_SummaryOfSignificantAccountingPoliciesTable_37134486D2208A9545E8197706847901" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RangeAxis" xlink:label="loc_us-gaap_RangeAxis_C51CF4A8EAA7EB4448BC19770684979D" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesTable_37134486D2208A9545E8197706847901" xlink:to="loc_us-gaap_RangeAxis_C51CF4A8EAA7EB4448BC19770684979D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_E7CB5FFD124FB39EBE7219770684ACC3" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeAxis_C51CF4A8EAA7EB4448BC19770684979D" xlink:to="loc_us-gaap_RangeMember_E7CB5FFD124FB39EBE7219770684ACC3" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_MinimumMember" xlink:label="loc_us-gaap_MinimumMember_AE1A76E3496C7A1394ED19770684E863" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeMember_E7CB5FFD124FB39EBE7219770684ACC3" xlink:to="loc_us-gaap_MinimumMember_AE1A76E3496C7A1394ED19770684E863" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_MaximumMember" xlink:label="loc_us-gaap_MaximumMember_102B52335B35660BA1E6197706842E67" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeMember_E7CB5FFD124FB39EBE7219770684ACC3" xlink:to="loc_us-gaap_MaximumMember_102B52335B35660BA1E6197706842E67" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_4683040948DAF2B1EF4E197706845D2C" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesTable_37134486D2208A9545E8197706847901" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_4683040948DAF2B1EF4E197706845D2C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_0699B3C781BB54A2B18E197706841B4C" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_4683040948DAF2B1EF4E197706845D2C" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_0699B3C781BB54A2B18E197706841B4C" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SeaSpineInc.Member" xlink:label="loc_iart_SeaSpineInc.Member_B4D6E7CDE7478D9BD41419770684AA02" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_0699B3C781BB54A2B18E197706841B4C" xlink:to="loc_iart_SeaSpineInc.Member_B4D6E7CDE7478D9BD41419770684AA02" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="loc_us-gaap_DisposalGroupClassificationAxis_81A5AEAF7702CA987C8919770684F950" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesTable_37134486D2208A9545E8197706847901" xlink:to="loc_us-gaap_DisposalGroupClassificationAxis_81A5AEAF7702CA987C8919770684F950" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="loc_us-gaap_DisposalGroupClassificationDomain_18AD4F3A77245036B9E5197706849779" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationAxis_81A5AEAF7702CA987C8919770684F950" xlink:to="loc_us-gaap_DisposalGroupClassificationDomain_18AD4F3A77245036B9E5197706849779" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember" xlink:label="loc_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_2075E913A28A9113395E1977068466EF" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationDomain_18AD4F3A77245036B9E5197706849779" xlink:to="loc_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMember_2075E913A28A9113395E1977068466EF" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_421C8345276600CE84C5197706843DA5" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesTable_37134486D2208A9545E8197706847901" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_421C8345276600CE84C5197706843DA5" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_9B946F1A1D8984FD223819770685325A" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_421C8345276600CE84C5197706843DA5" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_9B946F1A1D8984FD223819770685325A" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_ConfluentSurgicalInc.Member" xlink:label="loc_iart_ConfluentSurgicalInc.Member_201AF246A0854D43E0021977068511FB" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_9B946F1A1D8984FD223819770685325A" xlink:to="loc_iart_ConfluentSurgicalInc.Member_201AF246A0854D43E0021977068511FB" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementByRestatementPeriodAndAmountAxis" xlink:label="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementByRestatementPeriodAndAmountAxis_D633DAFDE9581C8F998519770685C506" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesTable_37134486D2208A9545E8197706847901" xlink:to="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementByRestatementPeriodAndAmountAxis_D633DAFDE9581C8F998519770685C506" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AdjustmentsForErrorCorrectionDomain" xlink:label="loc_us-gaap_AdjustmentsForErrorCorrectionDomain_66028C34EB97AF76AA9B19770685B4E1" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementByRestatementPeriodAndAmountAxis_D633DAFDE9581C8F998519770685C506" xlink:to="loc_us-gaap_AdjustmentsForErrorCorrectionDomain_66028C34EB97AF76AA9B19770685B4E1" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DeferredTaxAccountsin2011ErrorMember" xlink:label="loc_iart_DeferredTaxAccountsin2011ErrorMember_8972DE629BD5A934EF50197706857C02" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsForErrorCorrectionDomain_66028C34EB97AF76AA9B19770685B4E1" xlink:to="loc_iart_DeferredTaxAccountsin2011ErrorMember_8972DE629BD5A934EF50197706857C02" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ConcentrationRiskByBenchmarkAxis" xlink:label="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_D2976529D83C0AF9988A197706853394" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesTable_37134486D2208A9545E8197706847901" xlink:to="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_D2976529D83C0AF9988A197706853394" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ConcentrationRiskBenchmarkDomain" xlink:label="loc_us-gaap_ConcentrationRiskBenchmarkDomain_7D6C9713CDB4AE524E191977068560E4" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_D2976529D83C0AF9988A197706853394" xlink:to="loc_us-gaap_ConcentrationRiskBenchmarkDomain_7D6C9713CDB4AE524E191977068560E4" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SalesRevenueNetMember" xlink:label="loc_us-gaap_SalesRevenueNetMember_7AEC4F3C45F3D758F427197706851843" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_7D6C9713CDB4AE524E191977068560E4" xlink:to="loc_us-gaap_SalesRevenueNetMember_7AEC4F3C45F3D758F427197706851843" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StatementScenarioAxis" xlink:label="loc_us-gaap_StatementScenarioAxis_17CB52B0E8DDFF0C819F19770685B49A" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesTable_37134486D2208A9545E8197706847901" xlink:to="loc_us-gaap_StatementScenarioAxis_17CB52B0E8DDFF0C819F19770685B49A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScenarioUnspecifiedDomain" xlink:label="loc_us-gaap_ScenarioUnspecifiedDomain_C96DE60B1E6E35C8360C197706856139" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementScenarioAxis_17CB52B0E8DDFF0C819F19770685B49A" xlink:to="loc_us-gaap_ScenarioUnspecifiedDomain_C96DE60B1E6E35C8360C197706856139" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RestatementAdjustmentMember" xlink:label="loc_us-gaap_RestatementAdjustmentMember_74A9484D8D164191B3411977068527CB" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScenarioUnspecifiedDomain_C96DE60B1E6E35C8360C197706856139" xlink:to="loc_us-gaap_RestatementAdjustmentMember_74A9484D8D164191B3411977068527CB" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PropertyPlantAndEquipmentByTypeAxis" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_F7598345D2EB0BE521B3197706851F47" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesTable_37134486D2208A9545E8197706847901" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_F7598345D2EB0BE521B3197706851F47" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PropertyPlantAndEquipmentTypeDomain" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_1C54CCC28F050BF7CC69197706857EB6" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_F7598345D2EB0BE521B3197706851F47" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_1C54CCC28F050BF7CC69197706857EB6" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ComputerEquipmentMember" xlink:label="loc_us-gaap_ComputerEquipmentMember_78AF20611EEABAEF9F5B19770685CCAD" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_1C54CCC28F050BF7CC69197706857EB6" xlink:to="loc_us-gaap_ComputerEquipmentMember_78AF20611EEABAEF9F5B19770685CCAD" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_680484BF0916A86619CA1977068529FC" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesTable_37134486D2208A9545E8197706847901" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_680484BF0916A86619CA1977068529FC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_07FBCFD50AF8767C442D19770686F031" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_680484BF0916A86619CA1977068529FC" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_07FBCFD50AF8767C442D19770686F031" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InProcessResearchAndDevelopmentMember" xlink:label="loc_us-gaap_InProcessResearchAndDevelopmentMember_E7BD879CA700EBAACF4B19770686696D" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_07FBCFD50AF8767C442D19770686F031" xlink:to="loc_us-gaap_InProcessResearchAndDevelopmentMember_E7BD879CA700EBAACF4B19770686696D" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TrademarksBrandNamesMember" xlink:label="loc_iart_TrademarksBrandNamesMember_2FF632E71A64E7A4F3E6197706864C12" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_07FBCFD50AF8767C442D19770686F031" xlink:to="loc_iart_TrademarksBrandNamesMember_2FF632E71A64E7A4F3E6197706864C12" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TechnologyMember" xlink:label="loc_iart_TechnologyMember_826DBF9D0EB9243D0ABE1977068616DF" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_07FBCFD50AF8767C442D19770686F031" xlink:to="loc_iart_TechnologyMember_826DBF9D0EB9243D0ABE1977068616DF" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StatementGeographicalAxis" xlink:label="loc_us-gaap_StatementGeographicalAxis_DAE5BEE15F16C013904019770686ECCB" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesTable_37134486D2208A9545E8197706847901" xlink:to="loc_us-gaap_StatementGeographicalAxis_DAE5BEE15F16C013904019770686ECCB" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SegmentGeographicalDomain" xlink:label="loc_us-gaap_SegmentGeographicalDomain_DB639141462021C3A53E197706867126" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementGeographicalAxis_DAE5BEE15F16C013904019770686ECCB" xlink:to="loc_us-gaap_SegmentGeographicalDomain_DB639141462021C3A53E197706867126" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_EuropeMember" xlink:label="loc_us-gaap_EuropeMember_2F9B55B537DC1FC3125C197706864134" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentGeographicalDomain_DB639141462021C3A53E197706867126" xlink:to="loc_us-gaap_EuropeMember_2F9B55B537DC1FC3125C197706864134" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SummaryOfSignificantAccountingPoliciesLineItems" xlink:label="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:type="locator" />
    <presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesTable_37134486D2208A9545E8197706847901" xlink:to="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DisposalGroupIncludingDiscontinuedOperationDistributionofSpinoffSharesPercent" xlink:label="loc_iart_DisposalGroupIncludingDiscontinuedOperationDistributionofSpinoffSharesPercent_B7398CEADC65F0EDD2A1197706860FAA" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_iart_DisposalGroupIncludingDiscontinuedOperationDistributionofSpinoffSharesPercent_B7398CEADC65F0EDD2A1197706860FAA" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_DisposalGroupIncludingDiscontinuedOperationSharesRequiredforIssuanceofSpinoffShare" xlink:label="loc_iart_DisposalGroupIncludingDiscontinuedOperationSharesRequiredforIssuanceofSpinoffShare_FF97C2B7706E6FD2B90F197706864B58" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_iart_DisposalGroupIncludingDiscontinuedOperationSharesRequiredforIssuanceofSpinoffShare_FF97C2B7706E6FD2B90F197706864B58" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_78B884A1B90208D63C4419770686F2F8" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_78B884A1B90208D63C4419770686F2F8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue_BF155F8B003C408FD87D197706862DF2" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue_BF155F8B003C408FD87D197706862DF2" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_InventoryCapitalizedExpenses" xlink:label="loc_iart_InventoryCapitalizedExpenses_B597DF65D36A9A9B932519770686839C" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_iart_InventoryCapitalizedExpenses_B597DF65D36A9A9B932519770686839C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_Depreciation" xlink:label="loc_us-gaap_Depreciation_9166B4ECD2BCA56DB9D8197706865203" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_Depreciation_9166B4ECD2BCA56DB9D8197706865203" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CapitalLeasedAssetsGross" xlink:label="loc_us-gaap_CapitalLeasedAssetsGross_F7020A3DA6CC7FC6C65A197706864C4F" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_CapitalLeasedAssetsGross_F7020A3DA6CC7FC6C65A197706864C4F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CapitalLeasesLesseeBalanceSheetAssetsByMajorClassAccumulatedDeprecation" xlink:label="loc_us-gaap_CapitalLeasesLesseeBalanceSheetAssetsByMajorClassAccumulatedDeprecation_DAF14FAFB8BBCC48AA9B197706869C7B" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_CapitalLeasesLesseeBalanceSheetAssetsByMajorClassAccumulatedDeprecation_DAF14FAFB8BBCC48AA9B197706869C7B" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InterestCostsCapitalizedAdjustment" xlink:label="loc_us-gaap_InterestCostsCapitalizedAdjustment_A1EA8E8CED9835DD3943197706862AD7" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_InterestCostsCapitalizedAdjustment_A1EA8E8CED9835DD3943197706862AD7" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NumberOfReportableSegments" xlink:label="loc_us-gaap_NumberOfReportableSegments_2FEA1A513B8B7445176C19770687E10E" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_NumberOfReportableSegments_2FEA1A513B8B7445176C19770687E10E" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_NumberofReportableSegments.GoodwillReallocated" xlink:label="loc_iart_NumberofReportableSegments.GoodwillReallocated_5DA3F6B98260C7692F5519B5C4ADD361" xlink:type="locator" />
    <presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_iart_NumberofReportableSegments.GoodwillReallocated_5DA3F6B98260C7692F5519B5C4ADD361" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_GoodwillImpairmentLoss" xlink:label="loc_us-gaap_GoodwillImpairmentLoss_CA5E7DCCE1BAE21FDADC19770687F102" xlink:type="locator" />
    <presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_GoodwillImpairmentLoss_CA5E7DCCE1BAE21FDADC19770687F102" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_OtherIndefiniteLivedIntangibleAssets" xlink:label="loc_us-gaap_OtherIndefiniteLivedIntangibleAssets_AD76D6C2A51ECE6BE949197706871C30" xlink:type="locator" />
    <presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_OtherIndefiniteLivedIntangibleAssets_AD76D6C2A51ECE6BE949197706871C30" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_0EF149C0BD68DFB7E3BF1977068774B3" xlink:type="locator" />
    <presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_0EF149C0BD68DFB7E3BF1977068774B3" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_67A6A658F1C06D36A10F197706879B75" xlink:type="locator" />
    <presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_67A6A658F1C06D36A10F197706879B75" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_EB511AB7D6A0560E048719770687EE6F" xlink:type="locator" />
    <presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_EB511AB7D6A0560E048719770687EE6F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsFinitelived" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsFinitelived_8AAAFBA99F4E9F17251019770687F089" xlink:type="locator" />
    <presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsFinitelived_8AAAFBA99F4E9F17251019770687F089" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AdjustmentForAmortization" xlink:label="loc_us-gaap_AdjustmentForAmortization_7D00C7CD0B662453D8D719770687BE8A" xlink:type="locator" />
    <presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_AdjustmentForAmortization_7D00C7CD0B662453D8D719770687BE8A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_BABF9F861C9B602BECF019770687B5BC" xlink:type="locator" />
    <presentationArc order="19" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_BABF9F861C9B602BECF019770687B5BC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_FFB4F877BE6628CE32CF1977068710E2" xlink:type="locator" />
    <presentationArc order="20" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_FFB4F877BE6628CE32CF1977068710E2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_FE8642FBC70518086104197706879374" xlink:type="locator" />
    <presentationArc order="21" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_FE8642FBC70518086104197706879374" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_298F706252B996DC1AB5197706871E94" xlink:type="locator" />
    <presentationArc order="22" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_298F706252B996DC1AB5197706871E94" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_FF71D80AA9017E85EBFF19770687F569" xlink:type="locator" />
    <presentationArc order="23" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_FF71D80AA9017E85EBFF19770687F569" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CostOfGoodsSoldAmortization" xlink:label="loc_us-gaap_CostOfGoodsSoldAmortization_60869330B04B67071FA31977068705A0" xlink:type="locator" />
    <presentationArc order="24" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_CostOfGoodsSoldAmortization_60869330B04B67071FA31977068705A0" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_CharitableContributions" xlink:label="loc_iart_CharitableContributions_89D54228B02F822756F919770687533D" xlink:type="locator" />
    <presentationArc order="25" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_iart_CharitableContributions_89D54228B02F822756F919770687533D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_UndistributedEarningsOfForeignSubsidiaries" xlink:label="loc_us-gaap_UndistributedEarningsOfForeignSubsidiaries_83E927779638E1D4F41519770687097A" xlink:type="locator" />
    <presentationArc order="26" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_UndistributedEarningsOfForeignSubsidiaries_83E927779638E1D4F41519770687097A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DeferredTaxLiabilityNotRecognizedAmountOfUnrecognizedDeferredTaxLiabilityUndistributedEarningsOfForeignSubsidiaries" xlink:label="loc_us-gaap_DeferredTaxLiabilityNotRecognizedAmountOfUnrecognizedDeferredTaxLiabilityUndistributedEarningsOfForeignSubsidiaries_94B8BD7294E36A3EC57419770687CD04" xlink:type="locator" />
    <presentationArc order="27" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_DeferredTaxLiabilityNotRecognizedAmountOfUnrecognizedDeferredTaxLiabilityUndistributedEarningsOfForeignSubsidiaries_94B8BD7294E36A3EC57419770687CD04" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShippingHandlingAndTransportationCosts" xlink:label="loc_us-gaap_ShippingHandlingAndTransportationCosts_C146B369106AC43709841977068775C7" xlink:type="locator" />
    <presentationArc order="28" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_ShippingHandlingAndTransportationCosts_C146B369106AC43709841977068775C7" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_ExtendedWarrantiesInYears" xlink:label="loc_iart_ExtendedWarrantiesInYears_84DBF352F175C163FF2719770687306A" xlink:type="locator" />
    <presentationArc order="29" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_iart_ExtendedWarrantiesInYears_84DBF352F175C163FF2719770687306A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ProductWarrantyAccrual" xlink:label="loc_us-gaap_ProductWarrantyAccrual_FD9C747B707514527158197706873FD8" xlink:type="locator" />
    <presentationArc order="30" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_ProductWarrantyAccrual_FD9C747B707514527158197706873FD8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DefinedBenefitPlanContributionsByEmployer" xlink:label="loc_us-gaap_DefinedBenefitPlanContributionsByEmployer_D92FF95F1F68A13D97411977068775D5" xlink:type="locator" />
    <presentationArc order="31" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_DefinedBenefitPlanContributionsByEmployer_D92FF95F1F68A13D97411977068775D5" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DefinedBenefitPlanRecognizedNetGainLossDueToSettlementsAndCurtailments1" xlink:label="loc_us-gaap_DefinedBenefitPlanRecognizedNetGainLossDueToSettlementsAndCurtailments1_A69DFFC07B4173F9431A197706888114" xlink:type="locator" />
    <presentationArc order="32" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_DefinedBenefitPlanRecognizedNetGainLossDueToSettlementsAndCurtailments1_A69DFFC07B4173F9431A197706888114" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PensionContributions" xlink:label="loc_us-gaap_PensionContributions_89B4D941E08D50B2AB96197706883947" xlink:type="locator" />
    <presentationArc order="33" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_PensionContributions_89B4D941E08D50B2AB96197706883947" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ConcentrationRiskPercentage1" xlink:label="loc_us-gaap_ConcentrationRiskPercentage1_3269B5529AEE9666260219770688DC2E" xlink:type="locator" />
    <presentationArc order="34" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_ConcentrationRiskPercentage1_3269B5529AEE9666260219770688DC2E" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_ConcentrationRiskNumberofCustomersOverBenchmark" xlink:label="loc_iart_ConcentrationRiskNumberofCustomersOverBenchmark_5A01E5EF4B8381099D0019770688D97F" xlink:type="locator" />
    <presentationArc order="35" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_iart_ConcentrationRiskNumberofCustomersOverBenchmark_5A01E5EF4B8381099D0019770688D97F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InterestPaid" xlink:label="loc_us-gaap_InterestPaid_5A10790B82C3BAD4095819770688884D" xlink:type="locator" />
    <presentationArc order="36" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_InterestPaid_5A10790B82C3BAD4095819770688884D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InterestPaidCapitalized" xlink:label="loc_us-gaap_InterestPaidCapitalized_F8631E81CDB97C92BF481977068892FF" xlink:type="locator" />
    <presentationArc order="37" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_InterestPaidCapitalized_F8631E81CDB97C92BF481977068892FF" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxesPaid" xlink:label="loc_us-gaap_IncomeTaxesPaid_348F114252804D108B5E19770688198E" xlink:type="locator" />
    <presentationArc order="38" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_IncomeTaxesPaid_348F114252804D108B5E19770688198E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CapitalExpendituresIncurredButNotYetPaid" xlink:label="loc_us-gaap_CapitalExpendituresIncurredButNotYetPaid_1CAEC2857F82BC69F9E5197706887032" xlink:type="locator" />
    <presentationArc order="39" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_SummaryOfSignificantAccountingPoliciesLineItems_7C92A68290BF221ACAEC1977068628E0" xlink:to="loc_us-gaap_CapitalExpendituresIncurredButNotYetPaid_1CAEC2857F82BC69F9E5197706887032" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/SummaryOfSignificantAccountingPoliciesPolicies" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BasisOfAccountingPolicyPolicyTextBlock" xlink:label="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_36880409E27914C7085CEFA5070FB747" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_36880409E27914C7085CEFA5070FB747" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ConsolidationPolicyTextBlock" xlink:label="loc_us-gaap_ConsolidationPolicyTextBlock_3D340C73FFA03B4041B1EFA5070F48FD" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_ConsolidationPolicyTextBlock_3D340C73FFA03B4041B1EFA5070F48FD" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_UseOfEstimates" xlink:label="loc_us-gaap_UseOfEstimates_F05507301C153D4B4C9BEFA5070F6C06" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_UseOfEstimates_F05507301C153D4B4C9BEFA5070F6C06" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ComparabilityOfPriorYearFinancialData" xlink:label="loc_us-gaap_ComparabilityOfPriorYearFinancialData_844E8DF78361F0F2AD0BEFA5070FB2C6" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_ComparabilityOfPriorYearFinancialData_844E8DF78361F0F2AD0BEFA5070FB2C6" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PriorPeriodReclassificationAdjustmentDescription" xlink:label="loc_us-gaap_PriorPeriodReclassificationAdjustmentDescription_D572E293780470130B5CEFA50710220F" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_PriorPeriodReclassificationAdjustmentDescription_D572E293780470130B5CEFA50710220F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CashAndCashEquivalentsPolicyTextBlock" xlink:label="loc_us-gaap_CashAndCashEquivalentsPolicyTextBlock_B25039B013671B2B5365EFA507105C7C" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_CashAndCashEquivalentsPolicyTextBlock_B25039B013671B2B5365EFA507105C7C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy" xlink:label="loc_us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy_E749600CB596009F8F65EFA999DF6525" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy_E749600CB596009F8F65EFA999DF6525" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_TradeAndOtherAccountsReceivablePolicy" xlink:label="loc_us-gaap_TradeAndOtherAccountsReceivablePolicy_D608399788D3F2EA111BEFA507106590" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_TradeAndOtherAccountsReceivablePolicy_D608399788D3F2EA111BEFA507106590" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InventoryPolicyTextBlock" xlink:label="loc_us-gaap_InventoryPolicyTextBlock_A929E14166D728D33EEBEFA50710C600" xlink:type="locator" />
    <presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_InventoryPolicyTextBlock_A929E14166D728D33EEBEFA50710C600" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PropertyPlantAndEquipmentPolicyTextBlock" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_C2803FA7F002C04558C9EFA50710F5BE" xlink:type="locator" />
    <presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_C2803FA7F002C04558C9EFA50710F5BE" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InterestCapitalizationPolicyPolicyTextBlock" xlink:label="loc_us-gaap_InterestCapitalizationPolicyPolicyTextBlock_BE5742D8FA833F506602EFA507100D63" xlink:type="locator" />
    <presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_InterestCapitalizationPolicyPolicyTextBlock_BE5742D8FA833F506602EFA507100D63" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsPolicyTextBlock" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsPolicyTextBlock_2E059A3AB735A00C9C60EFA5071003D8" xlink:type="locator" />
    <presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_GoodwillAndIntangibleAssetsPolicyTextBlock_2E059A3AB735A00C9C60EFA5071003D8" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ImpairmentOrDisposalOfLongLivedAssetsIncludingIntangibleAssetsPolicyPolicyTextBlock" xlink:label="loc_us-gaap_ImpairmentOrDisposalOfLongLivedAssetsIncludingIntangibleAssetsPolicyPolicyTextBlock_0A3847910D0D6EEC6160EFA50710F10B" xlink:type="locator" />
    <presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_ImpairmentOrDisposalOfLongLivedAssetsIncludingIntangibleAssetsPolicyPolicyTextBlock_0A3847910D0D6EEC6160EFA50710F10B" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_FoundationPolicyTextBlock" xlink:label="loc_iart_FoundationPolicyTextBlock_C1003EC9ACFADF1662D3EFA507109156" xlink:type="locator" />
    <presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_iart_FoundationPolicyTextBlock_C1003EC9ACFADF1662D3EFA507109156" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_DerivativesPolicyTextBlock" xlink:label="loc_us-gaap_DerivativesPolicyTextBlock_1FD374CE9BB326952466EFA507106751" xlink:type="locator" />
    <presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_DerivativesPolicyTextBlock_1FD374CE9BB326952466EFA507106751" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock" xlink:label="loc_us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_5AADC96267A166219850EFA507103E6E" xlink:type="locator" />
    <presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_5AADC96267A166219850EFA507103E6E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxPolicyTextBlock" xlink:label="loc_us-gaap_IncomeTaxPolicyTextBlock_B44FCBB5A978CD1B9D36EFA50715626F" xlink:type="locator" />
    <presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_IncomeTaxPolicyTextBlock_B44FCBB5A978CD1B9D36EFA50715626F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RevenueRecognitionPolicyTextBlock" xlink:label="loc_us-gaap_RevenueRecognitionPolicyTextBlock_031DD8DFD4A4991B311FEFA507151089" xlink:type="locator" />
    <presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_RevenueRecognitionPolicyTextBlock_031DD8DFD4A4991B311FEFA507151089" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShippingAndHandlingCostPolicyTextBlock" xlink:label="loc_us-gaap_ShippingAndHandlingCostPolicyTextBlock_D3541A1FC41AC81273DBEFA5071516FE" xlink:type="locator" />
    <presentationArc order="19" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_ShippingAndHandlingCostPolicyTextBlock_D3541A1FC41AC81273DBEFA5071516FE" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ExtendedProductWarrantyPolicy" xlink:label="loc_us-gaap_ExtendedProductWarrantyPolicy_E3E5B9F14A8CE8F2A18EEFA50715C820" xlink:type="locator" />
    <presentationArc order="20" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_ExtendedProductWarrantyPolicy_E3E5B9F14A8CE8F2A18EEFA50715C820" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ResearchAndDevelopmentExpensePolicy" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpensePolicy_64D9970F2A80BEC3631AEFA507158D11" xlink:type="locator" />
    <presentationArc order="21" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpensePolicy_64D9970F2A80BEC3631AEFA507158D11" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_CostsAssociatedWithExitOrDisposalActivitiesOrRestructuringsPolicyTextBlock" xlink:label="loc_us-gaap_CostsAssociatedWithExitOrDisposalActivitiesOrRestructuringsPolicyTextBlock_ACC66CC237C28C0B6DB3EFA50716F3EB" xlink:type="locator" />
    <presentationArc order="22" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_CostsAssociatedWithExitOrDisposalActivitiesOrRestructuringsPolicyTextBlock_ACC66CC237C28C0B6DB3EFA50716F3EB" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy" xlink:label="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_235B12CEAF03D205B15CEFA507161C96" xlink:type="locator" />
    <presentationArc order="23" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_235B12CEAF03D205B15CEFA507161C96" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PensionAndOtherPostretirementPlansPolicy" xlink:label="loc_us-gaap_PensionAndOtherPostretirementPlansPolicy_FA954E7E948FE5C8045CEFA50716DED4" xlink:type="locator" />
    <presentationArc order="24" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_PensionAndOtherPostretirementPlansPolicy_FA954E7E948FE5C8045CEFA50716DED4" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ConcentrationRiskCreditRisk" xlink:label="loc_us-gaap_ConcentrationRiskCreditRisk_75D4DE6985B1CEE5AAEBEFA507166A82" xlink:type="locator" />
    <presentationArc order="25" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_ConcentrationRiskCreditRisk_75D4DE6985B1CEE5AAEBEFA507166A82" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:label="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_9F1BA23569DC71A032A0EFA507169943" xlink:type="locator" />
    <presentationArc order="26" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_65455662326B4319D0DCEFA5070F38F4" xlink:to="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_9F1BA23569DC71A032A0EFA507169943" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/SummaryOfSignificantAccountingPoliciesScheduleOfChangesInAccountingEstimateDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_42EDBCBD603C2F50FA4B55ED5A41836E" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable" xlink:label="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_B8FC0CBF994747FC01EF55ED5A412EBE" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_42EDBCBD603C2F50FA4B55ED5A41836E" xlink:to="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_B8FC0CBF994747FC01EF55ED5A412EBE" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StatementScenarioAxis" xlink:label="loc_us-gaap_StatementScenarioAxis_9797780529CE5BDD52F155ED5A419796" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_B8FC0CBF994747FC01EF55ED5A412EBE" xlink:to="loc_us-gaap_StatementScenarioAxis_9797780529CE5BDD52F155ED5A419796" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScenarioUnspecifiedDomain" xlink:label="loc_us-gaap_ScenarioUnspecifiedDomain_0101C21802394EE5784455ED5A41EA21" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementScenarioAxis_9797780529CE5BDD52F155ED5A419796" xlink:to="loc_us-gaap_ScenarioUnspecifiedDomain_0101C21802394EE5784455ED5A41EA21" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RestatementAdjustmentMember" xlink:label="loc_us-gaap_RestatementAdjustmentMember_1BE34A6EC699DD8543CA55ED5A41F41D" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScenarioUnspecifiedDomain_0101C21802394EE5784455ED5A41EA21" xlink:to="loc_us-gaap_RestatementAdjustmentMember_1BE34A6EC699DD8543CA55ED5A41F41D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems" xlink:label="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_6AF50130E50FFE96536A55ED5A42D5FC" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_B8FC0CBF994747FC01EF55ED5A412EBE" xlink:to="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_6AF50130E50FFE96536A55ED5A42D5FC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="loc_us-gaap_IncomeStatementAbstract_B0BEDDF6E276A3966F3055ED5A429B24" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_6AF50130E50FFE96536A55ED5A42D5FC" xlink:to="loc_us-gaap_IncomeStatementAbstract_B0BEDDF6E276A3966F3055ED5A429B24" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_23F53AE68551C4072C2E55ED5A42B9F3" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_B0BEDDF6E276A3966F3055ED5A429B24" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_23F53AE68551C4072C2E55ED5A42B9F3" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/SummaryOfSignificantAccountingPoliciesScheduleOfChangesInCarryingAmountOfGoodwillDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_FFB53B79EAACE2C2C1881539298BFBAB" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_31528CAA2C5C72E327DC1539298C5096" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_FFB53B79EAACE2C2C1881539298BFBAB" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_31528CAA2C5C72E327DC1539298C5096" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_4345663A0D9379CB30DC1539298C4896" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_31528CAA2C5C72E327DC1539298C5096" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_4345663A0D9379CB30DC1539298C4896" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_BCF767082DFC92CA2F4E1539298CAFD2" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_4345663A0D9379CB30DC1539298C4896" xlink:to="loc_us-gaap_SegmentDomain_BCF767082DFC92CA2F4E1539298CAFD2" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SpecialtySurgicalSolutionsMember" xlink:label="loc_iart_SpecialtySurgicalSolutionsMember_1B86B2C5ECAC91FB30091539298C090A" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_BCF767082DFC92CA2F4E1539298CAFD2" xlink:to="loc_iart_SpecialtySurgicalSolutionsMember_1B86B2C5ECAC91FB30091539298C090A" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_OrthopedicsandTissueTechnologiesMember" xlink:label="loc_iart_OrthopedicsandTissueTechnologiesMember_56B9499E7C94DFB86F5E1539298C0658" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_BCF767082DFC92CA2F4E1539298CAFD2" xlink:to="loc_iart_OrthopedicsandTissueTechnologiesMember_56B9499E7C94DFB86F5E1539298C0658" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_25C28499E8F9CEAFCF591539298CFE09" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_31528CAA2C5C72E327DC1539298C5096" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_25C28499E8F9CEAFCF591539298CFE09" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_AB3C32251578571843311539298C8BCF" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_25C28499E8F9CEAFCF591539298CFE09" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_AB3C32251578571843311539298C8BCF" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_MedtronicMicroFranceMember" xlink:label="loc_iart_MedtronicMicroFranceMember_A3E41832281D6B0D27F71539298CB9F1" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_AB3C32251578571843311539298C8BCF" xlink:to="loc_iart_MedtronicMicroFranceMember_A3E41832281D6B0D27F71539298CB9F1" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_MetasurgMember" xlink:label="loc_iart_MetasurgMember_AED00F08457705A193F51539298C0103" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_AB3C32251578571843311539298C8BCF" xlink:to="loc_iart_MetasurgMember_AED00F08457705A193F51539298C0103" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TEIBiosciencesIncandTEIMedicalInc.Member" xlink:label="loc_iart_TEIBiosciencesIncandTEIMedicalInc.Member_83571F250F862C050B851539298C8447" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_AB3C32251578571843311539298C8BCF" xlink:to="loc_iart_TEIBiosciencesIncandTEIMedicalInc.Member_83571F250F862C050B851539298C8447" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TekmedMember" xlink:label="loc_iart_TekmedMember_0589C6277ACA21276CF61539298CABAC" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_AB3C32251578571843311539298C8BCF" xlink:to="loc_iart_TekmedMember_0589C6277ACA21276CF61539298CABAC" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_GoodwillAndOtherIntangibleAssetsLineItems" xlink:label="loc_iart_GoodwillAndOtherIntangibleAssetsLineItems_D38FBF881281C77BA9081539298CC806" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_31528CAA2C5C72E327DC1539298C5096" xlink:to="loc_iart_GoodwillAndOtherIntangibleAssetsLineItems_D38FBF881281C77BA9081539298CC806" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_GoodwillPurchaseAccountingAdjustments" xlink:label="loc_us-gaap_GoodwillPurchaseAccountingAdjustments_EA279A6A191627B4649B1539298C7DD2" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_GoodwillAndOtherIntangibleAssetsLineItems_D38FBF881281C77BA9081539298CC806" xlink:to="loc_us-gaap_GoodwillPurchaseAccountingAdjustments_EA279A6A191627B4649B1539298C7DD2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_41CB32AAFE36A50A79F41539298DBE31" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_GoodwillAndOtherIntangibleAssetsLineItems_D38FBF881281C77BA9081539298CC806" xlink:to="loc_us-gaap_Goodwill_41CB32AAFE36A50A79F41539298DBE31" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_GoodwillRollForward" xlink:label="loc_us-gaap_GoodwillRollForward_4942AC0A0E007D9A85C71539298DAB51" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_iart_GoodwillAndOtherIntangibleAssetsLineItems_D38FBF881281C77BA9081539298CC806" xlink:to="loc_us-gaap_GoodwillRollForward_4942AC0A0E007D9A85C71539298DAB51" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_C63F553F8E57D7A7563D1539298DABE3" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_4942AC0A0E007D9A85C71539298DAB51" xlink:to="loc_us-gaap_Goodwill_C63F553F8E57D7A7563D1539298DABE3" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_GoodwillAcquiredDuringPeriod" xlink:label="loc_us-gaap_GoodwillAcquiredDuringPeriod_2A1D1CEF0C3E49723BEE1539298D5E01" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_4942AC0A0E007D9A85C71539298DAB51" xlink:to="loc_us-gaap_GoodwillAcquiredDuringPeriod_2A1D1CEF0C3E49723BEE1539298D5E01" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_GoodwillTranslationAdjustments" xlink:label="loc_us-gaap_GoodwillTranslationAdjustments_3B81C8E4F983FD42C6361539298DC3F7" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_4942AC0A0E007D9A85C71539298DAB51" xlink:to="loc_us-gaap_GoodwillTranslationAdjustments_3B81C8E4F983FD42C6361539298DC3F7" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_6BA553AFA3B5C0960DCD1539298D914E" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_4942AC0A0E007D9A85C71539298DAB51" xlink:to="loc_us-gaap_Goodwill_6BA553AFA3B5C0960DCD1539298D914E" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/SummaryOfSignificantAccountingPoliciesScheduleOfInventoriesNetDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_9480B1B315B2DC37E0C355ED5A3F1398" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InventoryFinishedGoods" xlink:label="loc_us-gaap_InventoryFinishedGoods_F1CC5D7A695236922AF355ED5A3F5504" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9480B1B315B2DC37E0C355ED5A3F1398" xlink:to="loc_us-gaap_InventoryFinishedGoods_F1CC5D7A695236922AF355ED5A3F5504" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InventoryWorkInProcess" xlink:label="loc_us-gaap_InventoryWorkInProcess_8B055DE0E063D11A8D5055ED5A3F724E" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9480B1B315B2DC37E0C355ED5A3F1398" xlink:to="loc_us-gaap_InventoryWorkInProcess_8B055DE0E063D11A8D5055ED5A3F724E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InventoryRawMaterials" xlink:label="loc_us-gaap_InventoryRawMaterials_81B18E958DA7BE22177B55ED5A3F4572" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9480B1B315B2DC37E0C355ED5A3F1398" xlink:to="loc_us-gaap_InventoryRawMaterials_81B18E958DA7BE22177B55ED5A3F4572" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_InventoryNet" xlink:label="loc_us-gaap_InventoryNet_B804AD51C39744FDE60A55ED5A3F79C2" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9480B1B315B2DC37E0C355ED5A3F1398" xlink:to="loc_us-gaap_InventoryNet_B804AD51C39744FDE60A55ED5A3F79C2" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/SummaryOfSignificantAccountingPoliciesScheduleOfPropertyPlantAndEquipmentBalancesAndCorrespondingLivesDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_54B0B1BB30F3109D8BF618EF1EA6B868" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfPropertyPlantAndEquipmentTable" xlink:label="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_49B0AC7C2AFDFA358A9518EF1EA62EDA" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_54B0B1BB30F3109D8BF618EF1EA6B868" xlink:to="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_49B0AC7C2AFDFA358A9518EF1EA62EDA" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PropertyPlantAndEquipmentByTypeAxis" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_603771D9FCBE68900C8718EF1EA64ACA" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_49B0AC7C2AFDFA358A9518EF1EA62EDA" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_603771D9FCBE68900C8718EF1EA64ACA" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PropertyPlantAndEquipmentTypeDomain" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_2187E51424C87D4EF31F18EF1EA604F2" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_603771D9FCBE68900C8718EF1EA64ACA" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_2187E51424C87D4EF31F18EF1EA604F2" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LandMember" xlink:label="loc_us-gaap_LandMember_17F902A033B7EE219D5018EF1EA66B7A" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_2187E51424C87D4EF31F18EF1EA604F2" xlink:to="loc_us-gaap_LandMember_17F902A033B7EE219D5018EF1EA66B7A" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_BuildingAndBuildingImprovementsMember" xlink:label="loc_us-gaap_BuildingAndBuildingImprovementsMember_CA6FD0C9E5C426E9020818EF1EA60D67" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_2187E51424C87D4EF31F18EF1EA604F2" xlink:to="loc_us-gaap_BuildingAndBuildingImprovementsMember_CA6FD0C9E5C426E9020818EF1EA60D67" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_LeaseholdImprovementsMember" xlink:label="loc_us-gaap_LeaseholdImprovementsMember_20EA97F67A2F5F7898BC18EF1EA644BB" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_2187E51424C87D4EF31F18EF1EA604F2" xlink:to="loc_us-gaap_LeaseholdImprovementsMember_20EA97F67A2F5F7898BC18EF1EA644BB" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_MachineryAndEquipmentMember" xlink:label="loc_us-gaap_MachineryAndEquipmentMember_31118B830887A1A45ECA18EF1EA6E698" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_2187E51424C87D4EF31F18EF1EA604F2" xlink:to="loc_us-gaap_MachineryAndEquipmentMember_31118B830887A1A45ECA18EF1EA6E698" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_SurgicalInstrumentKitsMember" xlink:label="loc_iart_SurgicalInstrumentKitsMember_B67B2AE7C2F356AE45E218EF1EA63EE4" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_2187E51424C87D4EF31F18EF1EA604F2" xlink:to="loc_iart_SurgicalInstrumentKitsMember_B67B2AE7C2F356AE45E218EF1EA63EE4" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_InformationSystemsandHardwareMember" xlink:label="loc_iart_InformationSystemsandHardwareMember_1D837DA7CF5EDAD91C4718EF1EA65EBC" xlink:type="locator" />
    <presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_2187E51424C87D4EF31F18EF1EA604F2" xlink:to="loc_iart_InformationSystemsandHardwareMember_1D837DA7CF5EDAD91C4718EF1EA65EBC" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_FurnitureAndFixturesMember" xlink:label="loc_us-gaap_FurnitureAndFixturesMember_6EF828B7CA9D176DDB8518EF1EA64310" xlink:type="locator" />
    <presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_2187E51424C87D4EF31F18EF1EA604F2" xlink:to="loc_us-gaap_FurnitureAndFixturesMember_6EF828B7CA9D176DDB8518EF1EA64310" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ConstructionInProgressMember" xlink:label="loc_us-gaap_ConstructionInProgressMember_1CAC604D9D48BF8A89D018EF1EA65E4C" xlink:type="locator" />
    <presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_2187E51424C87D4EF31F18EF1EA604F2" xlink:to="loc_us-gaap_ConstructionInProgressMember_1CAC604D9D48BF8A89D018EF1EA65E4C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RangeAxis" xlink:label="loc_us-gaap_RangeAxis_CB09B1654BB9AA726D0D18EF1EA7329F" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_49B0AC7C2AFDFA358A9518EF1EA62EDA" xlink:to="loc_us-gaap_RangeAxis_CB09B1654BB9AA726D0D18EF1EA7329F" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_6DE6C73F4ED891BC140318EF1EA70A52" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeAxis_CB09B1654BB9AA726D0D18EF1EA7329F" xlink:to="loc_us-gaap_RangeMember_6DE6C73F4ED891BC140318EF1EA70A52" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_MinimumMember" xlink:label="loc_us-gaap_MinimumMember_166CFC50B77BC9BDEEE018EF1EA77612" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeMember_6DE6C73F4ED891BC140318EF1EA70A52" xlink:to="loc_us-gaap_MinimumMember_166CFC50B77BC9BDEEE018EF1EA77612" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_MaximumMember" xlink:label="loc_us-gaap_MaximumMember_36D5372E985474C0B3D418EF1EA72661" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeMember_6DE6C73F4ED891BC140318EF1EA70A52" xlink:to="loc_us-gaap_MaximumMember_36D5372E985474C0B3D418EF1EA72661" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PropertyPlantAndEquipmentLineItems" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentLineItems_7C966939D3A4EAAEFB6C18EF1EA75BC9" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_49B0AC7C2AFDFA358A9518EF1EA62EDA" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentLineItems_7C966939D3A4EAAEFB6C18EF1EA75BC9" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PropertyPlantAndEquipmentGross" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_3A1D7854D484EEEB930A18EF1EA7F254" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_7C966939D3A4EAAEFB6C18EF1EA75BC9" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_3A1D7854D484EEEB930A18EF1EA7F254" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_4C03F3CD041E166A5FCE18EF1EA78666" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_7C966939D3A4EAAEFB6C18EF1EA75BC9" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_4C03F3CD041E166A5FCE18EF1EA78666" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_CEF74E1329124A9D96FD18EF1EA7C507" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_7C966939D3A4EAAEFB6C18EF1EA75BC9" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_CEF74E1329124A9D96FD18EF1EA7C507" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PropertyPlantAndEquipmentUsefulLife" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentUsefulLife_ABE3FF2BF407F2C9D63E18EF1EA71BE9" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_7C966939D3A4EAAEFB6C18EF1EA75BC9" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentUsefulLife_ABE3FF2BF407F2C9D63E18EF1EA71BE9" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/SummaryOfSignificantAccountingPoliciesTables" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_D8992DEA5F54882D1D455C56BD356388" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfInventoryCurrentTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_E95AA8F5903DD6856FB25C56BD352A66" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_D8992DEA5F54882D1D455C56BD356388" xlink:to="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_E95AA8F5903DD6856FB25C56BD352A66" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_PropertyPlantAndEquipmentTextBlock" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTextBlock_14F1F6C39E43B99928165C56BD35048C" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_D8992DEA5F54882D1D455C56BD356388" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTextBlock_14F1F6C39E43B99928165C56BD35048C" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfGoodwillTextBlock" xlink:label="loc_us-gaap_ScheduleOfGoodwillTextBlock_9826C98740949E5E62A35C56BD3516D6" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_D8992DEA5F54882D1D455C56BD356388" xlink:to="loc_us-gaap_ScheduleOfGoodwillTextBlock_9826C98740949E5E62A35C56BD3516D6" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTableTextBlock_7203B05CA809704336445C753B1CF480" xlink:type="locator" />
    <presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_D8992DEA5F54882D1D455C56BD356388" xlink:to="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTableTextBlock_7203B05CA809704336445C753B1CF480" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTableTextBlock_1EA01F67465AD5EEEE975C76F5D8C7DA" xlink:type="locator" />
    <presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_D8992DEA5F54882D1D455C56BD356388" xlink:to="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTableTextBlock_1EA01F67465AD5EEEE975C76F5D8C7DA" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/TreasuryStock" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_TreasuryStockTransactionsExcludingValueOfSharesReissuedAbstract" xlink:label="loc_us-gaap_TreasuryStockTransactionsExcludingValueOfSharesReissuedAbstract_C41B672234F0E386964855ED5926A0C2" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_TreasuryStockTextBlock" xlink:label="loc_us-gaap_TreasuryStockTextBlock_1E39D6112066F148758C55ED59263BB5" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TreasuryStockTransactionsExcludingValueOfSharesReissuedAbstract_C41B672234F0E386964855ED5926A0C2" xlink:to="loc_us-gaap_TreasuryStockTextBlock_1E39D6112066F148758C55ED59263BB5" xlink:type="arc" />
  </presentationLink>
  <presentationLink xlink:role="http://integralife.com/role/TreasuryStockNarrativeDetails" xlink:type="extended">
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_TreasuryStockTransactionsExcludingValueOfSharesReissuedAbstract" xlink:label="loc_us-gaap_TreasuryStockTransactionsExcludingValueOfSharesReissuedAbstract_9E8C41E722F45AB7EE37227F1ABAB07D" xlink:type="locator" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AcceleratedShareRepurchasesTable" xlink:label="loc_us-gaap_AcceleratedShareRepurchasesTable_1FF6FC81EFC04185D904227F1ABAEC2E" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TreasuryStockTransactionsExcludingValueOfSharesReissuedAbstract_9E8C41E722F45AB7EE37227F1ABAB07D" xlink:to="loc_us-gaap_AcceleratedShareRepurchasesTable_1FF6FC81EFC04185D904227F1ABAEC2E" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareRepurchaseProgramAxis" xlink:label="loc_us-gaap_ShareRepurchaseProgramAxis_7A79A091309F27590FE4227F1ABA6B59" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AcceleratedShareRepurchasesTable_1FF6FC81EFC04185D904227F1ABAEC2E" xlink:to="loc_us-gaap_ShareRepurchaseProgramAxis_7A79A091309F27590FE4227F1ABA6B59" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_ShareRepurchaseProgramDomain" xlink:label="loc_us-gaap_ShareRepurchaseProgramDomain_50B67AAFDCBC0096D7C9227F1ABAE17A" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareRepurchaseProgramAxis_7A79A091309F27590FE4227F1ABA6B59" xlink:to="loc_us-gaap_ShareRepurchaseProgramDomain_50B67AAFDCBC0096D7C9227F1ABAE17A" xlink:type="arc" />
    <loc xlink:href="iart-20151231.xsd#iart_TwoThousandFourteenShareRepurchaseProgramMember" xlink:label="loc_iart_TwoThousandFourteenShareRepurchaseProgramMember_DAAF0CC74CC405C5514B227F1ABA420D" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareRepurchaseProgramDomain_50B67AAFDCBC0096D7C9227F1ABAE17A" xlink:to="loc_iart_TwoThousandFourteenShareRepurchaseProgramMember_DAAF0CC74CC405C5514B227F1ABA420D" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_AcceleratedShareRepurchasesLineItems" xlink:label="loc_us-gaap_AcceleratedShareRepurchasesLineItems_C95493735FEC46F50C5D227F1ABA2EC4" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AcceleratedShareRepurchasesTable_1FF6FC81EFC04185D904227F1ABAEC2E" xlink:to="loc_us-gaap_AcceleratedShareRepurchasesLineItems_C95493735FEC46F50C5D227F1ABA2EC4" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockRepurchaseProgramAuthorizedAmount1" xlink:label="loc_us-gaap_StockRepurchaseProgramAuthorizedAmount1_643A6517082E19D08513227F1ABA1458" xlink:type="locator" />
    <presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AcceleratedShareRepurchasesLineItems_C95493735FEC46F50C5D227F1ABA2EC4" xlink:to="loc_us-gaap_StockRepurchaseProgramAuthorizedAmount1_643A6517082E19D08513227F1ABA1458" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1" xlink:label="loc_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_30F1A8117BC571D578F2227F1ABAC602" xlink:type="locator" />
    <presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AcceleratedShareRepurchasesLineItems_C95493735FEC46F50C5D227F1ABA2EC4" xlink:to="loc_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_30F1A8117BC571D578F2227F1ABAC602" xlink:type="arc" />
    <loc xlink:href="http://xbrl.fasb.org/us-gaap/2015/elts/us-gaap-2015-01-31.xsd#us-gaap_TreasuryStockSharesAcquired" xlink:label="loc_us-gaap_TreasuryStockSharesAcquired_134CFAD95DB6F9B48269227F1ABA4C53" xlink:type="locator" />
    <presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AcceleratedShareRepurchasesLineItems_C95493735FEC46F50C5D227F1ABA2EC4" xlink:to="loc_us-gaap_TreasuryStockSharesAcquired_134CFAD95DB6F9B48269227F1ABA4C53" xlink:type="arc" />
  </presentationLink>
</linkbase>
