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  <xsd:element id="iart_ComponentsOfInterestExpenseTableTableTextBlock" name="ComponentsOfInterestExpenseTableTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_ConcentrationRiskNumberofCustomersOverBenchmark" name="ConcentrationRiskNumberofCustomersOverBenchmark" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_ConfluentSurgicalInc.Member" name="ConfluentSurgicalInc.Member" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_DebtInstrumentConvertibleNumberofDebtInstrumentsPendingConversion" name="DebtInstrumentConvertibleNumberofDebtInstrumentsPendingConversion" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="iart_DeferredTaxAccountsin2011ErrorMember" name="DeferredTaxAccountsin2011ErrorMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_DeferredTaxAssetsCurrentClassificationAbstract" name="DeferredTaxAssetsCurrentClassificationAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_DeferredTaxAssetsFederalandStateTaxCreditCarryforwardsNoncurrent" name="DeferredTaxAssetsFederalandStateTaxCreditCarryforwardsNoncurrent" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="iart_DeferredTaxAssetsInventoryNoncurrent" name="DeferredTaxAssetsInventoryNoncurrent" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="iart_DeferredTaxAssetsNoncurrentClassificationAbstract" name="DeferredTaxAssetsNoncurrentClassificationAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_DeferredTaxAssetsOtherCurrent" name="DeferredTaxAssetsOtherCurrent" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="iart_DeferredTaxAssetsOtherNoncurrent" name="DeferredTaxAssetsOtherNoncurrent" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="iart_DeferredTaxAssetsTaxCreditCarryforwardsCurrent" name="DeferredTaxAssetsTaxCreditCarryforwardsCurrent" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="iart_DeferredTaxAssetsTaxCreditCarryforwardsNoncurrent" name="DeferredTaxAssetsTaxCreditCarryforwardsNoncurrent" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="iart_DeferredTaxAssetsTaxDeferredExpenseCompensationandBenefitsCompensatedAbsencesNoncurrent" name="DeferredTaxAssetsTaxDeferredExpenseCompensationandBenefitsCompensatedAbsencesNoncurrent" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="iart_DeferredTaxAssetsTaxDeferredExpenseCompensationandBenefitsEmployeeBonusesNoncurrent" name="DeferredTaxAssetsTaxDeferredExpenseCompensationandBenefitsEmployeeBonusesNoncurrent" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="iart_DeferredTaxAssetsTaxDeferredExpenseReservesandAccrualsAllowanceforDoubtfulAccountsNoncurrent" name="DeferredTaxAssetsTaxDeferredExpenseReservesandAccrualsAllowanceforDoubtfulAccountsNoncurrent" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="iart_DeferredTaxLiabilitiesCurrentClassificationAbstract" name="DeferredTaxLiabilitiesCurrentClassificationAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_DeferredTaxLiabilitiesGoodwillandIntangibleAssetsIntangibleandFixedAssets" name="DeferredTaxLiabilitiesGoodwillandIntangibleAssetsIntangibleandFixedAssets" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="iart_DeferredTaxLiabilitiesNetNoncurrent" name="DeferredTaxLiabilitiesNetNoncurrent" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="iart_DeferredTaxLiabilitiesNoncurrentClassificationAbstract" name="DeferredTaxLiabilitiesNoncurrentClassificationAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_DeferredTaxLiabilitiesOtherCurrent" name="DeferredTaxLiabilitiesOtherCurrent" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="iart_DeferredTaxLiabilitiesOtherNoncurrent" name="DeferredTaxLiabilitiesOtherNoncurrent" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="iart_DeferredTaxLiabilityMember" name="DeferredTaxLiabilityMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_DerivativeInstrumentsAndHedgingActivitiesDisclosureLineItems" name="DerivativeInstrumentsAndHedgingActivitiesDisclosureLineItems" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_DerivativePriceOfCallTransactionStrikePrice" name="DerivativePriceOfCallTransactionStrikePrice" nillable="true" substitutionGroup="xbrli:item" type="num:perShareItemType" xbrli:periodType="instant" />
  <xsd:element id="iart_DisposalGroupIncludingDiscontinuedOperationAccruedCompensationCurrent" name="DisposalGroupIncludingDiscontinuedOperationAccruedCompensationCurrent" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="iart_DisposalGroupIncludingDiscontinuedOperationDistributionofSpinoffSharesPercent" name="DisposalGroupIncludingDiscontinuedOperationDistributionofSpinoffSharesPercent" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_DisposalGroupIncludingDiscontinuedOperationOperatingExpenseandCostofGoodsSold" name="DisposalGroupIncludingDiscontinuedOperationOperatingExpenseandCostofGoodsSold" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="iart_DisposalGroupIncludingDiscontinuedOperationOtherIncomeExpenseNet" name="DisposalGroupIncludingDiscontinuedOperationOtherIncomeExpenseNet" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="iart_DisposalGroupIncludingDiscontinuedOperationSharesRequiredforIssuanceofSpinoffShare" name="DisposalGroupIncludingDiscontinuedOperationSharesRequiredforIssuanceofSpinoffShare" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_DocumentAndEntityInformationAbstract" name="DocumentAndEntityInformationAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_EarliestConversionDate" name="EarliestConversionDate" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_EffectiveForeignIncomeTaxRateReconciliationContinuingOperations" name="EffectiveForeignIncomeTaxRateReconciliationContinuingOperations" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_EffectiveForeignIncomeTaxRateReconciliationIncreaseDecreaseDuringPeriodPercent" name="EffectiveForeignIncomeTaxRateReconciliationIncreaseDecreaseDuringPeriodPercent" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_EffectiveIncomeTaxRateReconciliationChangeinDeferredTaxAssetsValuationAllowanceDuetoAcquisitionPercent" name="EffectiveIncomeTaxRateReconciliationChangeinDeferredTaxAssetsValuationAllowanceDuetoAcquisitionPercent" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_EffectiveIncomeTaxRateReconciliationDeductionIntercompanyInventoryPercent" name="EffectiveIncomeTaxRateReconciliationDeductionIntercompanyInventoryPercent" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_EffectiveIncomeTaxRateReconciliationIncreaseDecreaseDuringPeriodPercent" name="EffectiveIncomeTaxRateReconciliationIncreaseDecreaseDuringPeriodPercent" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseLegalandProfessionalPercent" name="EffectiveIncomeTaxRateReconciliationNondeductibleExpenseLegalandProfessionalPercent" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_EmployeeStockPurchasePlanProceeds" name="EmployeeStockPurchasePlanProceeds" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="iart_EstimatedTaxLiabilityonUndistributedEarningsofForeignSubsidiaries" name="EstimatedTaxLiabilityonUndistributedEarningsofForeignSubsidiaries" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="iart_ExtendedWarrantiesInYears" name="ExtendedWarrantiesInYears" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_FairValueInputProbabilityofEvent" name="FairValueInputProbabilityofEvent" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_FederalFundsMember" name="FederalFundsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_FiveYearOptionLeaseFromNovember12032ThroughOctober312037Member" name="FiveYearOptionLeaseFromNovember12032ThroughOctober312037Member" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_FiveYearOptionLeaseFromNovember12037ThroughOctober312042Member" name="FiveYearOptionLeaseFromNovember12037ThroughOctober312042Member" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_FoundationPolicyTextBlock" name="FoundationPolicyTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_GoodwillAndOtherIntangibleAssetsLineItems" name="GoodwillAndOtherIntangibleAssetsLineItems" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_ImpairmentofIntangibleAssetsFinitelivedNumberofAssetsImpaired" name="ImpairmentofIntangibleAssetsFinitelivedNumberofAssetsImpaired" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_IncomeTaxLineItems" name="IncomeTaxLineItems" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
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  <xsd:element id="iart_IncreaseDecreasetoUncertainTaxAccrual" name="IncreaseDecreasetoUncertainTaxAccrual" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="iart_IncreaseInAuthorizedShares" name="IncreaseInAuthorizedShares" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_IndemnificationPeriodOneMember" name="IndemnificationPeriodOneMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_IndemnificationPeriodTwoMember" name="IndemnificationPeriodTwoMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_InformationSystemsandHardwareMember" name="InformationSystemsandHardwareMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_InformationTechnologyandAdministrativeSupportMember" name="InformationTechnologyandAdministrativeSupportMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_IntegraSupplierContractMember" name="IntegraSupplierContractMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_InterestExpenseDebtExcludingAmortizationInterestCostsCapitalized" name="InterestExpenseDebtExcludingAmortizationInterestCostsCapitalized" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="iart_InventoryCapitalizedExpenses" name="InventoryCapitalizedExpenses" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_JulyTwoThousandFourteenAmendmentMember" name="JulyTwoThousandFourteenAmendmentMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_MaximumAverageConversionValueOfNotes" name="MaximumAverageConversionValueOfNotes" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_MaximumSellingPriceOfCompanysCommonStock" name="MaximumSellingPriceOfCompanysCommonStock" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_MedtronicMicroFranceMember" name="MedtronicMicroFranceMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_MetasurgMember" name="MetasurgMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_NetDeferredTaxAssetsCurrentAfterValuationAllowance" name="NetDeferredTaxAssetsCurrentAfterValuationAllowance" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="iart_NetDeferredTaxAssetsNoncurrentAfterValuationAllowance" name="NetDeferredTaxAssetsNoncurrentAfterValuationAllowance" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="iart_NonFormerChiefExecutiveOfficerMember" name="NonFormerChiefExecutiveOfficerMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_NonIssuedVestedRestrictedStockUnits" name="NonIssuedVestedRestrictedStockUnits" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="instant" />
  <xsd:element id="iart_NumberofReportableSegments.GoodwillReallocated" name="NumberofReportableSegments.GoodwillReallocated" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_OptionToExtendLeaseYears" name="OptionToExtendLeaseYears" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_OptionToRenewLease" name="OptionToRenewLease" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_OrthopedicsandTissueTechnologiesMember" name="OrthopedicsandTissueTechnologiesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_OtherComprehensiveIncomeLossNetofTaxPortionAttributabletoParentNetofSpinoff" name="OtherComprehensiveIncomeLossNetofTaxPortionAttributabletoParentNetofSpinoff" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="iart_PaymentOfAccretedInterestCashFlow" name="PaymentOfAccretedInterestCashFlow" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="iart_PaymentPerYearToRelatedPartyLessor" name="PaymentPerYearToRelatedPartyLessor" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="iart_PaymentstoAcquireBusinessesPaymentforBusinessInterest" name="PaymentstoAcquireBusinessesPaymentforBusinessInterest" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="iart_PaymentstoAcquireBusinessesPaymentsforTransitionalSupplyAgreement" name="PaymentstoAcquireBusinessesPaymentsforTransitionalSupplyAgreement" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="iart_PercentOfManufacturingFacilityOwnedByCorporationWhoseShareholdersAreTrustsWhoseBeneficiariesIncludeFamilyMembersOfCompanysFormerChairman" name="PercentOfManufacturingFacilityOwnedByCorporationWhoseShareholdersAreTrustsWhoseBeneficiariesIncludeFamilyMembersOfCompanysFormerChairman" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_PeriodForExtendedLease" name="PeriodForExtendedLease" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_PrincipalAmountOfNotesPerAverageTradingPrice" name="PrincipalAmountOfNotesPerAverageTradingPrice" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="iart_PrincipalAmountToBeConsideredForConversionPurpose" name="PrincipalAmountToBeConsideredForConversionPurpose" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_RelatedPartiesMember" name="RelatedPartiesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_RelatedPartyMember" name="RelatedPartyMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_RelatedPartySharedManagementNumberofCommonEmployees" name="RelatedPartySharedManagementNumberofCommonEmployees" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_ReleasedMember" name="ReleasedMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_RestOfWorldMember" name="RestOfWorldMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_RestrictedStockPerformanceStockAndContractStockMember" name="RestrictedStockPerformanceStockAndContractStockMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_SaltoandFuturaMember" name="SaltoandFuturaMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_ScheduleOfCompanysIdentifiableIntangibleAssetsTable" name="ScheduleOfCompanysIdentifiableIntangibleAssetsTable" nillable="true" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_ScheduleOfNetSalesAndOperatingIncomeByReportableSegmentTableTableTextBlock" name="ScheduleOfNetSalesAndOperatingIncomeByReportableSegmentTableTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_ScheduleOfShareBasedCompensationArrangementByShareBasedPaymentAwardVestedAndNonVestedAxis" name="ScheduleOfShareBasedCompensationArrangementByShareBasedPaymentAwardVestedAndNonVestedAxis" nillable="true" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_ScheduleOfShareBasedCompensationArrangementByShareBasedPaymentAwardVestedAndNonVestedDomain" name="ScheduleOfShareBasedCompensationArrangementByShareBasedPaymentAwardVestedAndNonVestedDomain" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_SeaSpineInc.Member" name="SeaSpineInc.Member" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_SeaSpineMember" name="SeaSpineMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_SegmentProfitLoss" name="SegmentProfitLoss" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="iart_SegmentReportingInformationNumberofProductsOffered" name="SegmentReportingInformationNumberofProductsOffered" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_SellingGeneralAndAdministrativeMember" name="SellingGeneralAndAdministrativeMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_SeniorCreditFacilityAxis" name="SeniorCreditFacilityAxis" nillable="true" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_SeniorCreditFacilityDomain" name="SeniorCreditFacilityDomain" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_SeniorCreditFacilityMember" name="SeniorCreditFacilityMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_ShareBasedCompensationArrangementByShareBasedPaymentAwardExpirationPeriodDirectors" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardExpirationPeriodDirectors" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_ShareBasedCompensationArrangementByShareBasedPaymentAwardExpirationPeriodEmployees" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardExpirationPeriodEmployees" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfPlans" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfPlans" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_ShareBasedCompensationArrangementByShareBasedPaymentAwardVestingPeriodEmployees" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardVestingPeriodEmployees" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_SharebasedCompensationArrangementbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsModificationUponSpinoffDescription" name="SharebasedCompensationArrangementbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsModificationUponSpinoffDescription" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_SharebasedCompensationArrangementbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsSurrenderedUponSpinoffDescription" name="SharebasedCompensationArrangementbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsSurrenderedUponSpinoffDescription" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsModificationUponSpinOff" name="SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsModificationUponSpinOff" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_SharebasedCompensationArrangementsbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsModificationUponSpinoffWeightedAverageGrantDateFairValueExercisePrice" name="SharebasedCompensationArrangementsbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsModificationUponSpinoffWeightedAverageGrantDateFairValueExercisePrice" nillable="true" substitutionGroup="xbrli:item" type="num:perShareItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_SharebasedCompensationArrangementsbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsSurrenderedUponSpinoffWeightedAverageGrantDateFairValueExercisePrice" name="SharebasedCompensationArrangementsbySharebasedPaymentAwardEquityInstrumentOtherthanOptionsSurrenderedUponSpinoffWeightedAverageGrantDateFairValueExercisePrice" nillable="true" substitutionGroup="xbrli:item" type="num:perShareItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_SharebasedCompensationArrangementsbySharebasedPaymentAwardOptionsModificationUponSpinOffWeightedAverageExercisePrice" name="SharebasedCompensationArrangementsbySharebasedPaymentAwardOptionsModificationUponSpinOffWeightedAverageExercisePrice" nillable="true" substitutionGroup="xbrli:item" type="num:perShareItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_SpecialtySurgicalSolutionsMember" name="SpecialtySurgicalSolutionsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_StrikePriceOfWarrantTransactions" name="StrikePriceOfWarrantTransactions" nillable="true" substitutionGroup="xbrli:item" type="num:perShareItemType" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="iart_SummaryOfSignificantAccountingPoliciesLineItems" name="SummaryOfSignificantAccountingPoliciesLineItems" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_SummaryOfSignificantAccountingPoliciesTable" name="SummaryOfSignificantAccountingPoliciesTable" nillable="true" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_SupplierRelationshipsIdentifiableIntangibleAssetsMember" name="SupplierRelationshipsIdentifiableIntangibleAssetsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_SurgicalInstrumentKitsMember" name="SurgicalInstrumentKitsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_SwinglineLoanMember" name="SwinglineLoanMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_TEIBiosciencesInc.Member" name="TEIBiosciencesInc.Member" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_TEIBiosciencesIncandTEIMedicalInc.Member" name="TEIBiosciencesIncandTEIMedicalInc.Member" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_TEIMedicalInc.Member" name="TEIMedicalInc.Member" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_TEIMember" name="TEIMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_TarsusMedicalIncMember" name="TarsusMedicalIncMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_TechnologyMember" name="TechnologyMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_TekmedMember" name="TekmedMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_TermLoanAmountOutstanding" name="TermLoanAmountOutstanding" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="iart_TermLoanMember" name="TermLoanMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_TermOfLease" name="TermOfLease" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_ThirdPartiesMember" name="ThirdPartiesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_ThirdPartyInsurerMember" name="ThirdPartyInsurerMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_ToeProductFamilyMember" name="ToeProductFamilyMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_TrademarksBrandNamesMember" name="TrademarksBrandNamesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_TrademarksBrandNamesMiltexCUSALuxtecandOmniTractMember" name="TrademarksBrandNamesMiltexCUSALuxtecandOmniTractMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_TwoThousandAndTwoThousandOnePlanMember" name="TwoThousandAndTwoThousandOnePlanMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_TwoThousandFourteenShareRepurchaseProgramMember" name="TwoThousandFourteenShareRepurchaseProgramMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_TwoThousandSixteenSeniorConvertibleNotesMember" name="TwoThousandSixteenSeniorConvertibleNotesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_TwoThousandThreePlanMember" name="TwoThousandThreePlanMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_USInstrumentsMember" name="USInstrumentsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_USNeurosurgeryMember" name="USNeurosurgeryMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_UnrecognizedTaxBenefitsDecreasesDuringPeriodAbstract" name="UnrecognizedTaxBenefitsDecreasesDuringPeriodAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="iart_UnrecognizedTaxBenefitsIncreasesDuringPeriodAbstract" name="UnrecognizedTaxBenefitsIncreasesDuringPeriodAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="iart_UnrecognizedTaxBenefitsReductionsResultingFromOther" name="UnrecognizedTaxBenefitsReductionsResultingFromOther" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
</xsd:schema>
