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    <link:label id="lab_iart_ConfluentSurgicalInc.Member_346D7F86FD04ACA61FFDC8C2D2243D5C_terseLabel_en-US" xlink:label="lab_iart_ConfluentSurgicalInc.Member_346D7F86FD04ACA61FFDC8C2D2243D5C" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Confluent Surgical, Inc.</link:label>
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    <link:label id="lab_us-gaap_IncomeTaxExpenseBenefit_7E509C9A883709389CFCB7B2535BFD58_verboseLabel_en-US" xlink:label="lab_us-gaap_IncomeTaxExpenseBenefit_7E509C9A883709389CFCB7B2535BFD58" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Income tax benefit</link:label>
    <link:label id="lab_us-gaap_IncomeTaxExpenseBenefit_7E509C9A883709389CFCB7B2535BFD58_label_en-US" xlink:label="lab_us-gaap_IncomeTaxExpenseBenefit_7E509C9A883709389CFCB7B2535BFD58" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Income Tax Expense (Benefit)</link:label>
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    <link:label id="lab_us-gaap_NetIncomeLoss_AC09C11F75195F851A3AB7B2535B15E2_terseLabel_en-US" xlink:label="lab_us-gaap_NetIncomeLoss_AC09C11F75195F851A3AB7B2535B15E2" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Net income</link:label>
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    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NetIncomeLoss_AC09C11F75195F851A3AB7B2535B15E2" xlink:to="lab_us-gaap_NetIncomeLoss_AC09C11F75195F851A3AB7B2535B15E2" xlink:type="arc" />
    <link:label id="lab_us-gaap_ScheduleOfGoodwillTextBlock_31E4657C81D874814E8CA559794FF7B4_terseLabel_en-US" xlink:label="lab_us-gaap_ScheduleOfGoodwillTextBlock_31E4657C81D874814E8CA559794FF7B4" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Schedule of Changes in Carrying Amount of Goodwill</link:label>
    <link:label id="lab_us-gaap_ScheduleOfGoodwillTextBlock_31E4657C81D874814E8CA559794FF7B4_label_en-US" xlink:label="lab_us-gaap_ScheduleOfGoodwillTextBlock_31E4657C81D874814E8CA559794FF7B4" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Schedule of Goodwill [Table Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfGoodwillTextBlock" xlink:label="loc_us-gaap_ScheduleOfGoodwillTextBlock_31E4657C81D874814E8CA559794FF7B4" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ScheduleOfGoodwillTextBlock_31E4657C81D874814E8CA559794FF7B4" xlink:to="lab_us-gaap_ScheduleOfGoodwillTextBlock_31E4657C81D874814E8CA559794FF7B4" xlink:type="arc" />
    <link:label id="lab_iart_ScheduleOfDefiniteAndIndefiniteLivedIntangibleAssetsTableTableTextBlock_92493A18998A15D78AF3A559794F4B97_terseLabel_en-US" xlink:label="lab_iart_ScheduleOfDefiniteAndIndefiniteLivedIntangibleAssetsTableTableTextBlock_92493A18998A15D78AF3A559794F4B97" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Components of Company's Identifiable Intangible Assets</link:label>
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    <link:loc xlink:href="iart-20180630.xsd#iart_ScheduleOfDefiniteAndIndefiniteLivedIntangibleAssetsTableTableTextBlock" xlink:label="loc_iart_ScheduleOfDefiniteAndIndefiniteLivedIntangibleAssetsTableTableTextBlock_92493A18998A15D78AF3A559794F4B97" xlink:type="locator" />
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    <link:label id="lab_iart_TarsusMedicalInc.Member_90C9A671BD7A895395D5A559793F092F_terseLabel_en-US" xlink:label="lab_iart_TarsusMedicalInc.Member_90C9A671BD7A895395D5A559793F092F" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Tarsus</link:label>
    <link:label id="lab_iart_TarsusMedicalInc.Member_90C9A671BD7A895395D5A559793F092F_label_en-US" xlink:label="lab_iart_TarsusMedicalInc.Member_90C9A671BD7A895395D5A559793F092F" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Tarsus Medical, Inc. [Member]</link:label>
    <link:label id="lab_iart_TarsusMedicalInc.Member_90C9A671BD7A895395D5A559793F092F_documentation_en-US" xlink:label="lab_iart_TarsusMedicalInc.Member_90C9A671BD7A895395D5A559793F092F" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Tarsus Medical, Inc. [Member]</link:label>
    <link:loc xlink:href="iart-20180630.xsd#iart_TarsusMedicalInc.Member" xlink:label="loc_iart_TarsusMedicalInc.Member_90C9A671BD7A895395D5A559793F092F" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_iart_TarsusMedicalInc.Member_90C9A671BD7A895395D5A559793F092F" xlink:to="lab_iart_TarsusMedicalInc.Member_90C9A671BD7A895395D5A559793F092F" xlink:type="arc" />
    <link:label id="lab_us-gaap_ImpairmentOfIntangibleAssetsFinitelived_512316005F0F306054B9A559793FBE6E_verboseLabel_en-US" xlink:label="lab_us-gaap_ImpairmentOfIntangibleAssetsFinitelived_512316005F0F306054B9A559793FBE6E" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Impairment charge</link:label>
    <link:label id="lab_us-gaap_ImpairmentOfIntangibleAssetsFinitelived_512316005F0F306054B9A559793FBE6E_label_en-US" xlink:label="lab_us-gaap_ImpairmentOfIntangibleAssetsFinitelived_512316005F0F306054B9A559793FBE6E" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Impairment of Intangible Assets, Finite-lived</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsFinitelived" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsFinitelived_512316005F0F306054B9A559793FBE6E" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ImpairmentOfIntangibleAssetsFinitelived_512316005F0F306054B9A559793FBE6E" xlink:to="lab_us-gaap_ImpairmentOfIntangibleAssetsFinitelived_512316005F0F306054B9A559793FBE6E" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_024E0DC79CD2D62DE2ADA559793FEF25_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_024E0DC79CD2D62DE2ADA559793FEF25" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Expected annual amortization expense, 2018</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_024E0DC79CD2D62DE2ADA559793FEF25_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_024E0DC79CD2D62DE2ADA559793FEF25" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Remainder of Fiscal Year</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_024E0DC79CD2D62DE2ADA559793FEF25" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_024E0DC79CD2D62DE2ADA559793FEF25" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_024E0DC79CD2D62DE2ADA559793FEF25" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_A599B36B59CE5F5224F8A559793F04A3_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_A599B36B59CE5F5224F8A559793F04A3" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Expected annual amortization expense, 2019</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_A599B36B59CE5F5224F8A559793F04A3_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_A599B36B59CE5F5224F8A559793F04A3" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Year Two</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_A599B36B59CE5F5224F8A559793F04A3" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_A599B36B59CE5F5224F8A559793F04A3" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_A599B36B59CE5F5224F8A559793F04A3" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_C211D8EAD93F7B7156AEA559793F8889_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_C211D8EAD93F7B7156AEA559793F8889" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Expected annual amortization expense, 2020</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_C211D8EAD93F7B7156AEA559793F8889_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_C211D8EAD93F7B7156AEA559793F8889" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Year Three</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_C211D8EAD93F7B7156AEA559793F8889" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_C211D8EAD93F7B7156AEA559793F8889" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_C211D8EAD93F7B7156AEA559793F8889" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_9F90DB75B6CAD61934E4A559793F2315_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_9F90DB75B6CAD61934E4A559793F2315" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Expected annual amortization expense, 2021</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_9F90DB75B6CAD61934E4A559793F2315_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_9F90DB75B6CAD61934E4A559793F2315" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Year Four</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_9F90DB75B6CAD61934E4A559793F2315" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_9F90DB75B6CAD61934E4A559793F2315" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_9F90DB75B6CAD61934E4A559793F2315" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_542FC3EBE7A219096EEDA559793F4866_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_542FC3EBE7A219096EEDA559793F4866" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Expected annual amortization expense, 2022</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_542FC3EBE7A219096EEDA559793F4866_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_542FC3EBE7A219096EEDA559793F4866" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Year Five</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_542FC3EBE7A219096EEDA559793F4866" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_542FC3EBE7A219096EEDA559793F4866" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_542FC3EBE7A219096EEDA559793F4866" xlink:type="arc" />
    <link:label id="lab_iart_FiniteLivedIntangibleAssetsAmortizationExpenseYearSix_76277BC7F368C0F02F46A559793F7611_terseLabel_en-US" xlink:label="lab_iart_FiniteLivedIntangibleAssetsAmortizationExpenseYearSix_76277BC7F368C0F02F46A559793F7611" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Expected annual amortization expense, 2023</link:label>
    <link:label id="lab_iart_FiniteLivedIntangibleAssetsAmortizationExpenseYearSix_76277BC7F368C0F02F46A559793F7611_label_en-US" xlink:label="lab_iart_FiniteLivedIntangibleAssetsAmortizationExpenseYearSix_76277BC7F368C0F02F46A559793F7611" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Year Six</link:label>
    <link:label id="lab_iart_FiniteLivedIntangibleAssetsAmortizationExpenseYearSix_76277BC7F368C0F02F46A559793F7611_documentation_en-US" xlink:label="lab_iart_FiniteLivedIntangibleAssetsAmortizationExpenseYearSix_76277BC7F368C0F02F46A559793F7611" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Year Six</link:label>
    <link:loc xlink:href="iart-20180630.xsd#iart_FiniteLivedIntangibleAssetsAmortizationExpenseYearSix" xlink:label="loc_iart_FiniteLivedIntangibleAssetsAmortizationExpenseYearSix_76277BC7F368C0F02F46A559793F7611" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_iart_FiniteLivedIntangibleAssetsAmortizationExpenseYearSix_76277BC7F368C0F02F46A559793F7611" xlink:to="lab_iart_FiniteLivedIntangibleAssetsAmortizationExpenseYearSix_76277BC7F368C0F02F46A559793F7611" xlink:type="arc" />
    <link:label id="lab_iart_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearSix_2CC50FD9ADE79906123FA559793F4A7E_terseLabel_en-US" xlink:label="lab_iart_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearSix_2CC50FD9ADE79906123FA559793F4A7E" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Expected annual amortization expense, thereafter</link:label>
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