<SEC-DOCUMENT>0001209191-19-019753.txt : 20190315
<SEC-HEADER>0001209191-19-019753.hdr.sgml : 20190315
<ACCEPTANCE-DATETIME>20190315171725
ACCESSION NUMBER:		0001209191-19-019753
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20190313
FILED AS OF DATE:		20190315
DATE AS OF CHANGE:		20190315

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			CARUSO RICHARD E
		CENTRAL INDEX KEY:			0001187576

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-26224
		FILM NUMBER:		19685939

	MAIL ADDRESS:	
		STREET 1:		311 C ENTERPRISE DRIVE
		CITY:			PLAINSBORO
		STATE:			NJ
		ZIP:			08536

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			INTEGRA LIFESCIENCES HOLDINGS CORP
		CENTRAL INDEX KEY:			0000917520
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				510317849
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		311 ENTERPRISE DRIVE
		CITY:			PLAINSBORO
		STATE:			NJ
		ZIP:			08536
		BUSINESS PHONE:		6092750500

	MAIL ADDRESS:	
		STREET 1:		311 ENTERPRISE DRIVE
		CITY:			PLAINSBORO
		STATE:			NJ
		ZIP:			08536

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	INTEGRA LIFESCIENCES CORP
		DATE OF NAME CHANGE:	19950614
</SEC-HEADER>
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<TYPE>4
<SEQUENCE>1
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<DESCRIPTION>FORM 4 SUBMISSION
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        <issuerName>INTEGRA LIFESCIENCES HOLDINGS CORP</issuerName>
        <issuerTradingSymbol>IART</issuerTradingSymbol>
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            <rptOwnerName>CARUSO RICHARD E</rptOwnerName>
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            <rptOwnerStreet1>795 E LANCASTER AVENUE, SUITE 200</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>VILLANOVA</rptOwnerCity>
            <rptOwnerState>PA</rptOwnerState>
            <rptOwnerZipCode>19085</rptOwnerZipCode>
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                <directOrIndirectOwnership>
                    <value>I</value>
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                    <value>By Partnership</value>
                </natureOfOwnership>
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                <natureOfOwnership>
                    <value>By Son</value>
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        </nonDerivativeHolding>
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    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Non-Qualified Stock Option (right to buy)</value>
            </securityTitle>
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                <value>21.965</value>
            </conversionOrExercisePrice>
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                <value>2019-03-13</value>
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                    <value>9250</value>
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                <transactionPricePerShare>
                    <value>0.00</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
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            <exerciseDate>
                <footnoteId id="F1"/>
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            <expirationDate>
                <value>2019-05-17</value>
            </expirationDate>
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                <underlyingSecurityTitle>
                    <value>Common Stock</value>
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            <securityTitle>
                <value>Non-Qualified Stock Option (right to buy)</value>
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                <value>21.965</value>
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                    <value>20878</value>
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                    <value>0.00</value>
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                    <value>D</value>
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                <footnoteId id="F1"/>
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                <value>2019-05-17</value>
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    <footnotes>
        <footnote id="F1">25% of the stock options vest every quarter from the grant date of 5/17/2011</footnote>
        <footnote id="F2">This option was previously reported as covering 4,431 shares at an exercise price of $50.78 per share, but was adjusted pursuant to the anti-dilution provisions of the award in connection with the spin-off of SeaSpine Holdings Corporation on July 1, 2015 to 4,625 shares of common stock at an exercise price of $43.93 per share.</footnote>
        <footnote id="F3">In accordance with the terms of the stock option plan, the exercise price of the option and number of shares subject to the option have been adjusted to reflect the two-for-one stock split that occurred on December 21, 2016.</footnote>
        <footnote id="F4">This option was previously reported as covering 10,000 shares at an exercise price of $50.78 per share, but was adjusted pursuant to the anti-dilution provisions of the award in connection with the spin-off of SeaSpine Holdings Corporation on July 1, 2015 to 10,439 shares of common stock at an exercise price of $43.93 per share.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Dr. Richard E. Caruso</signatureName>
        <signatureDate>2019-03-15</signatureDate>
    </ownerSignature>
</ownershipDocument>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
