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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
 12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
OPERATING ACTIVITIES:      
Net income $ 50,201,000 $ 60,801,000 $ 64,743,000
Adjustments to reconcile net income to net cash provided by operating activities:      
Depreciation and amortization 109,462,000 110,730,000 88,945,000
Non-cash in-process research and development expense 64,916,000 0 0
Non-cash impairment charges 5,764,000 4,941,000 3,290,000
Deferred income tax benefit (19,046,000) (8,184,000) (67,304,000)
Share-based compensation 21,255,000 20,779,000 21,550,000
Amortization of debt issuance costs 5,390,000 6,270,000 2,722,000
Non-cash lease expense 5,060,000    
Non-cash lease expense   0 0
Realized loss on sale of short-term investments 0 0 2,287,000
Loss on disposal of property and equipment 1,821,000 1,385,000 6,989,000
Gain on divestiture of business 0 0 (2,645,000)
Change in fair value of contingent consideration and others 1,119,000 1,214,000 (4,710,000)
Changes in assets and liabilities, net of business acquisitions:      
Accounts receivable (9,428,000) (17,021,000) (89,698,000)
Inventories (43,308,000) 8,300,000 99,000
Prepaid expenses and other current assets 13,071,000 3,933,000 (33,808,000)
Other non-current assets 13,156,000 1,052,000 (914,000)
Accounts payable, accrued expenses and other current liabilities 14,666,000 3,588,000 95,321,000
Contract liabilities (607,000) 1,504,000 3,874,000
Other non-current liabilities (2,059,000) 391,000 23,803,000
Net cash provided by operating activities 231,433,000 199,683,000 114,544,000
INVESTING ACTIVITIES:      
Proceeds from sale of short-term investments 0 0 16,951,000
Proceeds from note receivable 752,000 910,000 483,000
Cash used in business acquisitions, net of cash acquired (30,509,000) 26,704,000 (1,241,946,000)
Acquired in-process research and development (64,995,000) 0 0
Purchases of property and equipment (69,537,000) (77,741,000) (43,503,000)
Proceeds from sales of property and equipment 37,000 422,000 293,000
Proceeds from divestiture of business 0 0 46,387,000
Net proceeds on swaps designated as net investment hedges 1,584,000 0 0
Net cash used in investing activities (162,668,000) (49,705,000) (1,221,335,000)
FINANCING ACTIVITIES:      
Proceeds from borrowings of long-term indebtedness 236,900,000 171,200,000 1,307,000,000
Payments on debt (246,100,000) (660,000,000) (117,000,000)
Net cash paid for contingent consideration 0 (38,196,000) (4,661,000)
Proceeds from the issuance of common stock, net of issuance costs 0 349,590,000 0
Debt issuance costs 0 (5,037,000) (19,043,000)
Proceeds from exercised stock options 6,948,000 9,392,000 9,774,000
Cash taxes paid in net equity settlement (6,514,000) (7,821,000) (7,123,000)
Net cash provided by (used in) financing activities (8,766,000) (180,872,000) 1,168,947,000
Effect of exchange rate changes on cash and cash equivalents 74,000 (5,203,000) 10,724,000
Net increase (decrease) in cash and cash equivalents 60,073,000 (36,097,000) 72,880,000
Cash and cash equivalents at beginning of period 138,838,000 174,935,000 102,055,000
Cash and cash equivalents at end of period $ 198,911,000 $ 138,838,000 $ 174,935,000