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| Name of Subsidiary | | State or Country of Incorporation or Organization | |
| Arkis Biosciences Inc. | | Delaware | |
| Ascension Orthopedics Limited | | United Kingdom | |
| Ascension Orthopedics, Inc. | | Delaware | |
| BIMECO, Inc. | | Florida | |
| BioD, LLC | | Delaware | |
| BioDlogics, LLC | | Delaware | |
| BioRecovery, LLC | | Delaware | |
| CardioDyne, Inc. | | Massachusetts | |
| Cathtec, Incorporated | | Massachusetts | |
| Caveangle Limited | | United Kingdom | |
| Confluent Surgical, Inc. | | Delaware | |
| Derma First Aid Products, Inc. | | Pennsylvania | |
| Derma Sciences Canada, Inc. | | Canada | |
| Derma Sciences Europe, Ltd. | | United Kingdom | |
| Derma Sciences, Inc. | | Delaware | |
| EndoSolutions, Inc. | | Delaware | |
| Fiber Imaging Technologies, Inc. | | Massachusetts | |
| GMS, Gesellschaft für medizinische Sondentechnik mbH | | Germany | |
| ILS Financing (Ireland) Limited | | Ireland | |
| ILS Financing Corporation | | Delaware | |
| ILS Services Switzerland Ltd. | | Switzerland | |
| INS Sweden AB | | Sweden | |
| Integra Burlington MA, Inc. (formerly known as Integra Radionics, Inc.) | | Delaware | |
| Integra Canada ULC (formerly known as Canada Microsurgical ULC) | | Canada | |
| Integra CI, Inc. | | Cayman Islands | |
| Integra Euro Holdings, Inc. | | Delaware | |
| Integra France Holdings SAS | | France | |
| Integra German Holdings GmbH | | Germany | |
| Integra GmbH | | Germany | |
| Integra Japan K.K. | | Japan | |
| Integra LifeSciences (Canada) Holdings, Inc. | | Delaware | |
| Integra LifeSciences (Ireland) Limited | | Ireland | |
| Integra LifeSciences (Shanghai) Co., Ltd. | | China | |
| Integra LifeSciences Austria GmbH | | Austria | |
| Integra LifeSciences Brazil Ltda. | | Brazil | |
| Integra LifeSciences Corporation | | Delaware | |
| Integra LifeSciences Italy S.r.l. | | Italy | |
| Integra LifeSciences Middle East FZ-LLC | | Dubai | |
| Integra LifeSciences NR Ireland Limited | | Ireland | |
| Integra LifeSciences Production Corporation | | Delaware | |
| Integra LifeSciences Sales LLC (f/k/a Integra Healthcare Products LLC) | | Delaware | |
| Integra LifeSciences Services (France) SAS | | France | |
| Integra LifeSciences Shared Services (Ireland) Limited | | Ireland | |
| Integra LifeSciences Singapore Pte. Ltd. | | Singapore | |
| Integra LifeSciences Spain, S.L. | | Spain | |
| Integra LifeSciences Switzerland Sárl | | Switzerland | |
| Integra LS (Benelux) NV | | Belgium | |
| Integra LS Mexico, S. DE R. L. DE C.V. | | Mexico | |
| Integra Luxtec, Inc. | | Massachusetts | |
| Integra ME GmbH | | Germany | |