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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
OPERATING ACTIVITIES: |  |  |
Net income | $ 180,550 | $ 169,075 | $ 133,892
Adjustments to reconcile net income to net cash provided by operating activities: |  |  |
Depreciation and amortization | 118,299 | 119,836 | 116,031
Non-cash in-process research and development expense | 0 | 0 | 519
Non-cash impairment charges | 0 | 2,754 | 0
Deferred income tax (benefit) provision | (4,585) | (2,755) | (64,138)
Share-based compensation | 27,725 | 36,210 | 19,590
Amortization of debt issuance costs and expenses associated with debt refinancing | 6,845 | 7,030 | 12,076
Non-cash lease expense | 2,816 | 3,834 | 2,955
Accretion of bond issuance discount | 0 | 0 | 15,415
Loss (Gain) on disposal of property and equipment and construction in-progress | (6,813) | 2,240 | 7,855
Gain from the sale of businesses | (644) | (41,798) | 0
Change in fair value of contingent consideration and others | (20,304) | (2,162) | 951
Changes in assets and liabilities: |  |  |
Accounts receivable | (33,905) | 7,265 | 52,105
Inventories | (29,124) | 5,374 | (48,348)
Prepaid expenses and other current assets | 8,612 | (21,143) | 1,632
Other non-current assets | (2,182) | 7,875 | 13,735
Accounts payable, accrued expenses and other current liabilities | 17,343 | 32,874 | (57,512)
Contract liabilities | 4,274 | 28 | (37)
Other non-current liabilities | (4,438) | (14,110) | (2,889)
Net cash provided by operating activities | 264,469 | 312,427 | 203,832
INVESTING ACTIVITIES: |  |  |
Purchases of property and equipment | (42,343) | (48,022) | (38,890)
Proceeds from sale of business | 23,960 | 190,468 | 0
Acquired in-process research and development and intangibles | (4,742) | (58) | (25,000)
Cash paid for business acquisitions, net of cash acquired | (51,509) | (303,910) | 0
Proceeds from sales of property and equipment | 11,145 | 3 | 3,657
Net proceeds (payments) on swaps designated as net investment hedges | 4,909 | 76 | (7,840)
Net cash used in investing activities | (58,580) | (161,443) | (68,073)
FINANCING ACTIVITIES: |  |  |
Proceeds from borrowings of long-term indebtedness | 40,750 | 25,500 | 171,500
Payments on debt | (148,550) | (125,500) | (441,000)
Purchase of option hedge on convertible notes | 0 | 0 | (104,248)
Proceeds from convertible notes issuance | 0 | 0 | 575,000
Proceeds from sale of stock purchase warrants | 0 | 0 | 44,563
Payment of debt issuance costs | 0 | (249) | (24,347)
Purchase of treasury stock | (125,000) | 0 | (100,000)
Proceeds from exercised stock options | 5,465 | 6,824 | 5,232
Cash taxes paid in net equity settlement | (24,618) | (4,801) | (5,075)
Net cash (used in) provided by financing activities | (251,953) | (98,226) | 121,625
Effect of exchange rate changes on cash and cash equivalents | (10,723) | (9,476) | 13,871
Net increase (decrease) in cash and cash equivalents | (56,787) | 43,282 | 271,255
Cash and cash equivalents at beginning of period | 513,448 | 470,166 | 198,911
Cash and cash equivalents at end of period | $ 456,661 | $ 513,448 | $ 470,166

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