<SEC-DOCUMENT>0001193125-22-266752-index.html : 20221021
<SEC-HEADER>0001193125-22-266752.hdr.sgml : 20221021
<ACCEPTANCE-DATETIME>20221021161642
ACCESSION NUMBER:		0001193125-22-266752
CONFORMED SUBMISSION TYPE:	424B5
PUBLIC DOCUMENT COUNT:		4
FILED AS OF DATE:		20221021
DATE AS OF CHANGE:		20221021

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Zymeworks Inc.
		CENTRAL INDEX KEY:			0001937653
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B5
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-259970-01
		FILM NUMBER:		221323939

	BUSINESS ADDRESS:	
		STREET 1:		108 PATRIOT DRIVE, SUITE A
		CITY:			MIDDLETOWN
		STATE:			DE
		ZIP:			19709
		BUSINESS PHONE:		206-337-1030

	MAIL ADDRESS:	
		STREET 1:		108 PATRIOT DRIVE, SUITE A
		CITY:			MIDDLETOWN
		STATE:			DE
		ZIP:			19709

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Zymeworks Delaware Inc.
		DATE OF NAME CHANGE:	20220712
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B5
<SEQUENCE>1
<FILENAME>d410387d424b5.htm
<DESCRIPTION>424B5
<TEXT>
Document 1 - file: d410387d424b5.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>2
<FILENAME>d410387dexfilingfees.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
Document 2 - file: d410387dexfilingfees.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>g410387g00a31.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: g410387g00a31.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>g410387g71w59.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: g410387g71w59.jpg

</DOCUMENT>
</SEC-DOCUMENT>