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Condensed Consolidated Statements of Loss and Comprehensive Loss - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Revenue    
Research and development collaborations (note 9) $ 27,110 $ 10,030
Operating expenses:    
Research and development 35,738 32,042
General and administrative 16,985 15,790
Total operating expenses 52,723 47,832
Loss from operations (25,613) (37,802)
Other income:    
Interest income 3,424 5,920
Other income, net (note 10) 49 304
Total other income, net 3,473 6,224
Loss before income taxes (22,140) (31,578)
Income tax expense (496) (75)
Net loss (22,636) (31,653)
Other comprehensive income (loss):    
Unrealized income (loss) on available for sale securities, net of tax of nil (note 5) 546 (1,121)
Total other comprehensive income (loss) 546 (1,121)
Comprehensive loss $ (22,090) $ (32,774)
Net loss per common share (note 4):    
Basic (in dollars per share) $ (0.30) $ (0.42)
Diluted (in dollars per share) $ (0.30) $ (0.42)
Weighted-average common stock outstanding (note 4):    
Basic (in shares) 75,171,020 76,214,833
Diluted (in shares) 75,226,387 76,248,158