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Equity (Details) (USD $)
 3 Months Ended 6 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended
Jun. 30, 2013
Jun. 30, 2012
Jun. 30, 2013
Jun. 30, 2012
Jun. 30, 2013
Warrants [Member]
Dec. 31, 2012
Warrants [Member]
Jun. 30, 2013
Contingent Warrants Related to Private Placement of Common Stock [Member]
Warrants [Member]
Jun. 30, 2013
Callable Warrants [Member]
Warrants [Member]
Jun. 30, 2013
Other [Member]
Warrants [Member]
Jun. 30, 2013
Cost of Products Sold [Member]
Jun. 30, 2012
Cost of Products Sold [Member]
Jun. 30, 2013
Cost of Products Sold [Member]
Jun. 30, 2012
Cost of Products Sold [Member]
Jun. 30, 2013
Research and Development [Member]
Jun. 30, 2012
Research and Development [Member]
Jun. 30, 2013
Research and Development [Member]
Jun. 30, 2012
Research and Development [Member]
Jun. 30, 2013
Selling, General and Administrative [Member]
Jun. 30, 2012
Selling, General and Administrative [Member]
Jun. 30, 2013
Selling, General and Administrative [Member]
Jun. 30, 2012
Selling, General and Administrative [Member]
Jun. 30, 2013
$0.50-$0.76 [Member]
Jun. 30, 2013
$0.87-$1.35 [Member]
Jun. 30, 2013
$1.40-$2.29 [Member]
Jun. 30, 2013
$2.33-$3.75 [Member]
Jun. 30, 2013
$3.95-$6.53 [Member]
Jun. 30, 2013
$6.60-$6.75 [Member]
Jun. 30, 2013
Maximum [Member]
Jun. 30, 2012
Maximum [Member]
Jun. 30, 2013
Minimum [Member]
Jun. 30, 2012
Minimum [Member]
Jun. 30, 2013
Stock Options [Member]
Jun. 30, 2013
Restricted Stock [Member]
Jun. 30, 2013
Restricted Stock [Member]
Maximum [Member]
Jun. 30, 2013
Restricted Stock [Member]
Minimum [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                                      
Number of share-based compensation plans 3                                                                    
Outstanding assumed options (in shares) 375,000   375,000                                                                
Additional shares authorized by Board of Directors (in shares) 6,000,000                                                                    
Shares authorized (in shares) 22,500,000   22,500,000                                                                
Expenses expected to be recognized over a weighted-average period                                                               2 years 4 months 24 days 2 years 6 months    
Number of shares granted (in shares)                                                                 280,000    
Weighted-average grant date fair value (in dollars per share)                                                                 $ 5.23    
Vesting period                                                                   3 years 1 year
Total unrecognized stock-based compensation related to time-based, nonvested restricted stock                                                                 $ 1,267,000    
Total unrecognized compensation expense 11,717,000   11,717,000                                                                
Number of shares [Roll forward]                                                                      
Outstanding, beginning of period (in shares)     13,614,135                                                                
Granted (in shares)     3,024,500                                                                
Exercised (in shares)     (489,197)                                                                
Unvested options forfeited (in shares)     (179,167)                                                                
Vested options expired (in shares)     (52,999)                                                                
Outstanding, end of period (in shares) 15,917,272   15,917,272                                                                
Vested at end of period (in shares) 7,044,063   7,044,063                                                                
Exercisable options, vested and expected to vest (in shares) 15,576,624   15,576,624                                                                
Weighted-Average Exercise Price [Roll forward]                                                                      
Outstanding, weighted average exercise price, beginning of period (in dollars per share)     $ 1.42                                                                
Granted, weighted average exercise price (in dollars per share)     $ 5.09                                                                
Exercised, weighted average exercise price (in dollars per share)     $ 1.11                                                                
Unvested options forfeited weighted-average exercise price (in dollars per share)     $ 3.82                                                                
Vested options expired weighted-average exercise price (in dollars per share)     $ 1.11                                                                
Outstanding, weighted average exercise price, end of period (in dollars per share) $ 2.10   $ 2.10                                                                
Vested at end of period weighted average exercise price (in dollars per share) $ 1.12   $ 1.12                                                                
Vested and expected to vest, weighted average exercise price (in dollars per share) $ 2.10   $ 2.10                                                                
Stock options, additional disclosures [Abstract]                                                                      
Vested at end of period weighted average remaining contractual term     6 years 6 months                                                                
Vested and expected to vest, weighted average remaining contractual term     7 years 10 months 24 days                                                                
Outstanding intrinsic value 78,906,155   78,906,155                                                                
Vested at end of period aggregate intrinsic value 41,809,325   41,809,325                                                                
Vested and expected to vest, aggregate intrinsic value 77,742,045   77,742,045                                                                
Exercised options, intrinsic value 2,345,000                                                                    
Exercise Price Range, lower range limit (in dollars per share)                                           $ 0.50 $ 0.87 $ 1.40 $ 2.33 $ 3.95 $ 6.6                
Exercise Price Range, upper range limit (in dollars per share)                                           $ 0.76 $ 1.35 $ 2.29 $ 3.75 $ 6.53 $ 6.75                
Number of outstanding options (in shares) 15,917,272   15,917,272                                     2,169,500 6,814,572 1,816,700 2,164,500 2,804,000 148,000                
Outstanding Options, weighted average remaining contractual term 7 years 10 months 24 days   7 years 10 months 24 days                                     4 years 9 months 18 days 8 years 1 month 6 days 6 years 4 months 24 days 9 years 2 months 12 days 9 years 8 months 12 days 9 years 10 months 24 days                
Outstanding Options, weighted average exercise price (in dollars per share) $ 2.10   $ 2.10                                     $ 0.67 $ 1.19 $ 1.63 $ 2.75 $ 5.00 $ 6.61                
Number of exercisable options (in shares) 7,044,063   7,044,063                                     2,169,500 3,356,198 1,518,365 0 0 0                
Exercisable Options, weighted average exercise price (in dollars per share) $ 1.12   $ 1.12                                     $ 0.67 $ 1.18 $ 1.65 $ 0 $ 0 $ 0                
Fair value options valuation assumptions [Abstract]                                                                      
Expected volatility (in hundredths)                                                       64.27% 57.60% 62.15% 57.30%        
Expected life       6 years                                               6 years   5 years 6 months          
Expected dividend yield (in hundredths)     0.00% 0.00%                                                              
Risk-free interest rate, minimum (in hundredths)     1.13% 2.24%                                                              
Risk-free interest rate, maximum (in hundredths)     0.85% 1.48%                                                              
Share-based Compensation [Abstract]                                                                      
Share-based compensation expense $ 1,502,447 $ 585,215 $ 2,487,239 $ 1,086,200           $ 72,669 $ 29,479 $ 122,831 $ 53,489 $ 122,789 $ 75,610 $ 198,767 $ 147,130 $ 1,306,989 $ 480,126 $ 2,165,641 $ 885,581                            
Weighted-average grant date fair value for options granted during the period (in dollars per share) $ 2.95                                                                    
Warrants, term 5 years                                                                    
Warrants, Number of Warrants [Roll Forward]                                                                      
Warrants outstanding, beginning of period (in shares)         2,132,002 3,129,168                                                          
Warrants exercised (in shares)             (62,500) (266,666) (668,000)                                                    
Warrants outstanding, end of period (in shares)         2,132,002 3,129,168                                                          
Warrants, Weighted-Average Exercise Price per Warrant [Roll Forward]                                                                      
Warrants outstanding, beginning of period (in dollars per share)         0.98 1.04                                                          
Warrants exercised (in dollars per share)             0.01 1.50 1.15                                                    
Warrants outstanding, end of period (in dollars per share)         0.98 1.04