<SEC-DOCUMENT>0001564590-18-024570-index.html : 20181022
<SEC-HEADER>0001564590-18-024570.hdr.sgml : 20181022
<ACCEPTANCE-DATETIME>20181022080019
ACCESSION NUMBER:		0001564590-18-024570
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		5
CONFORMED PERIOD OF REPORT:	20181021
ITEM INFORMATION:		Regulation FD Disclosure
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20181022
DATE AS OF CHANGE:		20181022

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Aeglea BioTherapeutics, Inc.
		CENTRAL INDEX KEY:			0001636282
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				464312787
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37722
		FILM NUMBER:		181131547

	BUSINESS ADDRESS:	
		STREET 1:		901 S. MOPAC EXPRESSWAY, STE. 250
		STREET 2:		BARTON OAKS PLAZA ONE
		CITY:			AUSTIN
		STATE:			TX
		ZIP:			78746
		BUSINESS PHONE:		(512) 942-2935

	MAIL ADDRESS:	
		STREET 1:		901 S. MOPAC EXPRESSWAY, STE. 250
		STREET 2:		BARTON OAKS PLAZA ONE
		CITY:			AUSTIN
		STATE:			TX
		ZIP:			78746
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>agle-8k_20181022.htm
<DESCRIPTION>8-K
<TEXT>
Document 1 - file: agle-8k_20181022.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>agle-ex991_105.htm
<DESCRIPTION>EX-99.1
<TEXT>
Document 2 - file: agle-ex991_105.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.2
<SEQUENCE>3
<FILENAME>agle-ex992_7.htm
<DESCRIPTION>EX-99.2
<TEXT>
Document 3 - file: agle-ex992_7.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>g0kwip1iiwo3000001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: g0kwip1iiwo3000001.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>gkjsyb2sco2t000001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: gkjsyb2sco2t000001.jpg

</DOCUMENT>
</SEC-DOCUMENT>