<SEC-DOCUMENT>0000899140-22-000301-index.html : 20220214
<SEC-HEADER>0000899140-22-000301.hdr.sgml : 20220214
<ACCEPTANCE-DATETIME>20220214162549
ACCESSION NUMBER:		0000899140-22-000301
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20220214
DATE AS OF CHANGE:		20220214
GROUP MEMBERS:		CUBIST SYSTEMATIC STRATEGIES, LLC
GROUP MEMBERS:		POINT72 CAPITAL ADVISORS, INC.
GROUP MEMBERS:		POINT72 HONG KONG LTD
GROUP MEMBERS:		STEVEN A. COHEN

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Aeglea BioTherapeutics, Inc.
		CENTRAL INDEX KEY:			0001636282
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				464312787
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-89456
		FILM NUMBER:		22632715

	BUSINESS ADDRESS:	
		STREET 1:		805 LAS CIMAS PARKWAY
		STREET 2:		SUITE 100
		CITY:			AUSTIN
		STATE:			TX
		ZIP:			78746
		BUSINESS PHONE:		(512) 942-2935

	MAIL ADDRESS:	
		STREET 1:		805 LAS CIMAS PARKWAY
		STREET 2:		SUITE 100
		CITY:			AUSTIN
		STATE:			TX
		ZIP:			78746

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Point72 Asset Management, L.P.
		CENTRAL INDEX KEY:			0001603466
		IRS NUMBER:				465064661
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		72 CUMMINGS POINT ROAD
		CITY:			STAMFORD
		STATE:			CT
		ZIP:			06902
		BUSINESS PHONE:		203-890-2000

	MAIL ADDRESS:	
		STREET 1:		72 CUMMINGS POINT ROAD
		CITY:			STAMFORD
		STATE:			CT
		ZIP:			06902
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>a011822a.htm
<DESCRIPTION>SCHEDULE 13G (AMENDMENT #2)
<TEXT>
Document 1 - file: a011822a.htm

</DOCUMENT>
</SEC-DOCUMENT>