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Asset Acquisition - Asset Acquisition Cost (Details) - USD ($) $ in Thousands |  | 3 Months Ended | 9 Months Ended
--- | --- | --- | ---
Jun. 22, 2023 | Sep. 30, 2023 | Sep. 30, 2022 | Sep. 30, 2023 | Sep. 30, 2022
Asset Acquisition [Line Items] |  |  |  |  |
Acquired in-process research and development |  | $ (298) | $ 0 | $ 130,188 | $ 0
Cash acquired |  |  |  | $ 3,035 | $ 0
Cost to acquire asset | $ 113,200 |  |  |  |
Spyre Therapeutics, Inc. |  |  |  |  |
Asset Acquisition [Line Items] |  |  |  |  |
Consideration transferred in Series A Preferred Stock and common stock | 109,979 |  |  |  |
Transaction costs incurred by Aeglea | 3,197 |  |  |  |
Acquired in-process research and development | 130,188 |  |  |  |
Cash acquired | 3,035 |  |  |  |
Assumed liabilities | (20,000) |  |  |  |
Cost to acquire asset | $ 113,176 |  |  |  |

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- Definition Amount of consideration transferred in asset acquisition. Includes, but is not limited to, cash, liability incurred by acquirer, and equity interest issued by acquirer. + References Reference 1: http://www.xbrl.org/2003/role/exampleRef -Topic 805 -SubTopic 50 -Name Accounting Standards Codification -Section 55 -Paragraph 1 -Publisher FASB -URI https://asc.fasb.org//1943274/2147479908/805-50-55-1 Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 805 -SubTopic 50 -Name Accounting Standards Codification -Section 25 -Paragraph 1 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480060/805-50-25-1 Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 805 -SubTopic 50 -Name Accounting Standards Codification -Section 30 -Paragraph 1 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480027/805-50-30-1 Reference 4: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 805 -SubTopic 50 -Name Accounting Standards Codification -Section 30 -Paragraph 2 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480027/805-50-30-2 + Details
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