EX-21.1 31 d518298dex211.htm EX-21.1

Exhibit 21.1

Subsidiaries of Aeglea BioTherapeutics, Inc.

Name of Subsidiary |  | Jurisdiction
Aeglea Development Company, Inc. |  | Delaware
AERase, Inc. |  | Delaware
AECase, Inc. |  | Delaware
AEMase, Inc. |  | Delaware
AE4ase, Inc. |  | Delaware
AE5ase, Inc. |  | Delaware
AE6ase, Inc. |  | Delaware
Aeglea Biotherapeutics UK Limited |  | England and Wales
Aeglea Ireland Limited |  | Ireland
Aeglea BioTherapeutics US LLC |  | Delaware
Spyre Therapeutics, LLC |  | Delaware