    <SEC-DOCUMENT>0001193125-23-205262-index.html : 20230808
    <SEC-HEADER>0001193125-23-205262.hdr.sgml : 20230808
    <ACCEPTANCE-DATETIME>20230807215127
    ACCESSION NUMBER:		0001193125-23-205262
    CONFORMED SUBMISSION TYPE:	PRE 14A
    PUBLIC DOCUMENT COUNT:		3
    CONFORMED PERIOD OF REPORT:	20230807
    FILED AS OF DATE:		20230808
    DATE AS OF CHANGE:		20230807

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Aeglea BioTherapeutics, Inc.
    		CENTRAL INDEX KEY:			0001636282
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				464312787
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		PRE 14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-37722
    		FILM NUMBER:		231149125

    	BUSINESS ADDRESS:
    		STREET 1:		221 CRESCENT STREET
    		STREET 2:		BUILDING 17, SUITE 102B
    		CITY:			WALTHAM
    		STATE:			MA
    		ZIP:			02453
    		BUSINESS PHONE:		6176515940

    	MAIL ADDRESS:
    		STREET 1:		221 CRESCENT STREET
    		STREET 2:		BUILDING 17, SUITE 102B
    		CITY:			WALTHAM
    		STATE:			MA
    		ZIP:			02453
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>PRE 14A
    <SEQUENCE>1
    <FILENAME>d520772dpre14a.htm
    <DESCRIPTION>PRE 14A
    <TEXT>
    Document 1 - file: d520772dpre14a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>g520772g00a02.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: g520772g00a02.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>g520772g00a56.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: g520772g00a56.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>